werner@aecom.YU.EDU (Craig Werner) (06/05/87)
The following is a second in a series of eclectic table of contents
to the current issue of Science. (15 May 1987, Vol 236, No. 4803)
1. Cloning of DNA segments in E. coli is limited to about 50,000
base pairs. Genetic analysis of higher organisms can only resolve down
to about 500,000 bp. This gap has recently been bridged by pulse-field
gel electrophoresis, but there is still no way to clone such large fragments
in E. coli. There still isn't, but Burke, Carle, and *Olson* describe a
technique to clone such things in yeast. p. 806.
2. Everything you always wanted to know about HTLV-4 can be found
in the article by Kanki et al (Essex), Human T-lymphotrophic Virus Type
4 and the Human Immunodeficiency Virus in West Africa, p. 827.
3. It has been known for some time that rats and humans remember
best things they learned before eating (presumably an evolutionary
adaptation to remembering good restaurants). A mechanism is proposed
in "Modulation of Memory processing by Cholecystokinin: Dependence
on the Vagus Nerve." Flood, Smith, and Morley, p. 832.
4. They always knew it would be there, but up to now nobody
had ever visualized it: "A Tunnel in the Large Ribosomal Subunit
Revealed by 3-D image reconstruction" Yonath, Leonard, and Wittman,
p. 813.
--
Craig Werner (MD/PhD '91)
!philabs!aecom!werner
(1935-14E Eastchester Rd., Bronx NY 10461, 212-931-2517)
"Satis multum illius nunc circum fertur."