[sci.bio] Antibody Production

carey@m.cs.uiuc.edu (06/30/90)

I would like to get information about using animals to produce
antibodies.

I would like to get articles about the side effects of the hyper-immune 
response.  Apparently, the large amount of antibodies tend to clog up
the kidneys.  I would like to get information on that.

I don't have any experience doing "medical" searches.  I assume that
they can help me at the medical library.  (but if someone can give
me a quick rundown it would be great)  What would I search for --
if I searched for "antibodies" I would think I would come up with 
billions of articles.  Does anyone know the catch-words for the 
relevant topics?

What are the legalities of using animals in a commercial environment?
I know that universities have a committee that reviews experiment's
protocols.  But if the work is not sponsored by a University what
needs to be done?

Also, I have been told there might be opportunities to get funding through
NIH or some other government agencies.  How difficult is that to do
if you are not affiliated with a University Lab, and how interested are
they in antibodies?

What level of purification is most useful to people?  Does anyone have
a spare centrifuge they want to get rid of?

I have a microbiologist to help with the details so there will be 
expertise there (as you can tell I don't have)


-----
John Carey
University of Illinois
Dept. of Computer Science
carey@a.cs.uiuc.edu
{uu-net,pur-ee,convex,...}!uiucdcs!carey