[sci.bio] The Mystery of the Golgi Stain

mmm@cup.portal.com (Mark Robert Thorson) (12/06/90)

When I was in college, it was unknown why the Golgi stain only affects
about one neuron in a thousand.  This stain has been crucial to the
understanding of neural structure at the cellular level (because it allows
individual cells in a tissue to be viewed in isolation), yet at that
time its selectivity was a mystery.

I'm wondering whether this mystery has been solved.  Does anyone yet
know why the Golgi stain seems to pick cells at random, while leaving
the surrounding tissue unstained?