[net.math] simplex algorithsm for curve fittin

leimkuhl@uiucdcsp.CS.UIUC.EDU (02/16/86)

One of my roommates is a biophysicist.  He's been using that program
to study models lately.  The instability for some problems is the result
of local minima on the surface associated with the curve.  You can get
reasonable confidence by "shaking" the surface after simplex settles down
(i.e. perturb the data and restart).  And of course you can always do a
goodness-of-fit test afterwards to get reasonable confidence.

-Ben Leimkuhler