GenBank-Updates@genbank.bio.net (08/17/90)
LOCUS MUSMX2 2426 bp ss-mRNA ROD 17-AUG-1990 DEFINITION Mouse interferon-induced Mx2 mRNA, presumably non-functional. ACCESSION J03368 KEYWORDS Mx protein; influenza virus resistance protein; pseudogene. SOURCE Mouse (BALB/c) embryo, cDNA to mRNA. ORGANISM Mus musculus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 2426) AUTHORS Staeheli,P. and Sutcliffe,J.G. TITLE Identification of a second interferon-regulated murine Mx gene JOURNAL Mol. Cell. Biol. 8, 4524-4528 (1988) STANDARD full staff_entry COMMENT Draft entry and computer-readable sequence for [1] kindly provided by P.Staeheli, 08-SEP-1988. The insertion mutation at position 1366 causes a frameshift. It is the only difference between Mx2 and the viable Mx1 gene. FEATURES from to/span description pept.ps 120 2088 pseudo-Mx protein pept 120 1391 ORF1 pept 1282 2088 ORF2 mut 1365 1367 gca in Mx2; ga in Mx1 BASE COUNT 705 a 549 c 636 g 536 t ORIGIN 83 bp upstream of AccI site; chromosome 16. 1 acactctgtc tccaagccgg gaggggtgag tattgcacag gattctgtgg agggatagag 61 gataccttct aaggcttctt tgtagacact gagtacccaa ctgagagaag aaataaaaga 121 tggttcttag cacagaagaa aacacaggcg ttgattcagt caacttaccc agtggagaga 181 ctggcctagg agagaaagac caggagtctg tgaacaatct ctgcagtcag tatgaggaga 241 aggtgcggcc ctgcattgac ctcatcgact ccctgccggc tctgggtgtg gagcaggacc 301 tggccctgcc tgccatcgct gtcattgggg atcagagttc tgggaagagc tctgtactag 361 aagcactgtc tggagtggcc ctccccagag gcagtggtat tgtcaccaga tgccctctgg 421 tgctgaaatt gaggaagctg aatgagggag aggagtggag aggcaaagtc tcctatgatg 481 acatcgaagt ggagctctct gatccttcag aggtggaaga ggccatcaac aagggtcaga 541 acttcattgc tggggtaggt ctggggatca gtgataagct cattagcctg gatgtcagct 601 ccccaaatgt cccagacctg actctcattg acctgcctgg aattaccagg gtggctgtag 661 gcaaccagcc tgcagacata ggacgccaga tcaagagact catcaagaca tacatccaaa 721 aacaggagac catcaacctg gtggtggtcc ccagcaatgt ggacattgcc accacagagg 781 ctctgagcat ggctcaggag gtggaccctg aaggggatag gaccataggg atcttgacca 841 agcccgatct ggtggacaga ggtactgaag acaaggtcgt ggatgtggtg cggaacctgg 901 tgtaccatct gaagaagggc tacatgatag tcaagtgcag aggtcagcag gacatccaag 961 agcagctgag cctgactgag gctcttcaga atgagcaaat cttcttcaag gaacaccctc 1021 atttcagagt tcttctggag gatgggaagg ccacagtgcc ctgcctggca gagagactga 1081 ccgcagagct catctcacac atctgtaaat ctcttcctct gctagaaaat caaataaagg 1141 aaagtcacca gagtgcaagt gaggagctgc agaagtacgg tatggacata ccagaagatg 1201 acagtgaaaa aactttcttc ctgatcgaaa aaatcaatgc ttttaaccag gacatcactg 1261 ccctagtaca aggggaagag aatgtggcag agggagaatg tcgcctattc accaggctcc 1321 gaaaagagtt cttgtcctgg agtaaggaga tcgaaaagaa tttcgcaaaa aggttatgct 1381 gttttatata atgaagtctg ggcatttgaa aagcagtatc gtggacgaga attgccaggg 1441 tttgtgaatt acaaaacatt tgagaacatt ataagaagac aaatcaaaac cctggaagag 1501 ccagctatag aaatgctgca cacggtcact gaaattgtac gagctgcctt tacaagtgtt 1561 tctgagaaaa atttttctga gttttataac ctccacagaa ctaccaagtc caaacttgaa 1621 gacatcagat tagaacaaga aaaggaagca gagatgtcga tccgactcca cttcaagatg 1681 gaacaaatta tctactgcca ggaccagatt tacagaggag ccttgcagaa ggtcagagag 1741 gaggaagctg aggaggagaa gaagacaaag catggcactt ccagttcctc tcagtcccaa 1801 gatttacaga cctcatccat ggctgagatc ttccagcatc tgaatgccta ccgccaggag 1861 gctcacaacc gcatctccag ccacgttccc ttgatcatcc agtatttcat cctgaaaatg 1921 tttgctgagc ggctgcagaa gggcatgctc cagctcctgc aggacaagga ttcctgcagc 1981 tggctcctga aggagcagag tgacacaagc gagaagagga agttcctgaa ggagaggctg 2041 gcaaggctgg cccaggctcg gcgccggcta gccaaattcc ctggttaagc tggctctgtc 2101 cttccctgtg tttcctggat tgtgattcag ggacagaagg gctcctgcct ttcctggtag 2161 ctataccacc agcctttatg ctctgataag tgctagcact cagatttgaa ggagctttct 2221 gctcactctg agataggaag agaaagaggc tctcaaagct cagcaagtag atgggtagag 2281 gaagccactt tgctaataag acaacggctt caccctgagt actcttcttg cccaccattt 2341 agcacactgc tagaaataaa tatttgatgt acaaatggga gctgcctgtt acattcctta 2401 ataaaccact tttctttaaa aaaaaa //