GenBank-Updates@genbank.bio.net (08/17/90)
LOCUS STRPBP2BA 1455 bp ds-DNA BCT 17-AUG-1990
DEFINITION S.sanguis penicillin-binding protein 2B (penA) gene, 5' end.
ACCESSION M32226
KEYWORDS penicillin-binding protein 2B.
SOURCE S.sanguis (strain 1907-penicillin resistant) DNA.
ORGANISM Streptococcus sanguis
Prokaryota; Bacteria; Firmicutes; Gram-positive cocci;
Streptococcaceae.
REFERENCE 1 (bases 1 to 1455)
AUTHORS Dowson,C.G., Hutchison,A., Woodford,N., Johnson,A.P.,
George,R.C. and Spratt,B.G.
TITLE Penicillin-resistant viridans streptococci have obtained altered
penicillin-binding protein genes from penicillin-resistant strains
of Streptococcus pneumoniae
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 5858-5862 (1990)
STANDARD full staff_entry
COMMENT Draft entry and computer-readable sequence [1] kindly submitted by
B.G. Spratt, 16-FEB-1990, for release after publication.
FEATURES from to/span description
pept < 1 1436 penicillin-binding protein 2B (penA) (AA at 3)
site 549 551 residue acylated by penicillin
BASE COUNT 422 a 296 c 330 g 407 t
ORIGIN
1 ctgttattgc ctctatttca aaggagatgc ctggcattag tatttctact tcttgggatc
61 gaaaggtttt ggaaacttcc ctttcttcta tagtagggag tgtatccagt gaaaaagctg
121 gtctcccagc ggaagaagca gaatcctatc ttaaaaaagg ctattctcta aatgaccgtg
181 ttggaacctc ctatttggaa aagcaatatg aagagacctt acaaggaaaa cgctcggtaa
241 aagaaatcca tctggataaa tatggcaata tggaaagcgt ggacacaatt gaggaaggta
301 gtaagggaaa caatatcaaa ctgaccattg atttggcctt ccaagatagc gtggatgctt
361 tgctgaaaag ttatttcaat tccgagctag gaaatggtgg agctaaatat tctgaaggtg
421 tctatgcagt cgcccttaac ccaaaaacag gtgctgtttt atccatgtca gggatcaaac
481 atgacctgaa aacgggagag ttgactcctg attccttggg aacggtaacc aatgtctttg
541 tcccaggttc ggttgtcaag gctgcgacca tcagctcagg ttgggaaaat ggtgttttat
601 caggaaacca aaccttaaca gatcagccta ttgttttcca aggttcagct cccatttatt
661 cttggtataa attggcatat ggatcttttc ctattacagc tgtggaagcc ttggagtatt
721 catccaatgc ttacatggtt caaaccgctc ttggaatcat gggccagacc tatcaaccaa
781 atatgtttgt tggaaccagc aatttggaaa cagctatggg aaaacttcgt gcgacctttg
841 gcgaatatgg cttgggggct gcgaccggaa ttgacctacc agatgaatct actggatttg
901 ttcccaaaga gtatagcttt gctaattaca tcaccaattc ctttgggcag tttgataact
961 atacgcccat gcagttggct cagtatgtag caactattgc aaataatggt gttcgtgtgg
1021 ctcctcgtat tgttgaaggc atttatggta ataatgataa gggaggactg ggtgacttga
1081 ttcagcaact gcaaccgaca gagatgaata aggtcaatat atccgactcc gatatgagca
1141 tcttgcacca aggtttttat caggttgccc atggtactag tggattgaca actggacgtg
1201 ccttttcaaa tggtgccttg gtatccatta gcggaaaaac aggtacagcc gaaagctatg
1261 tggcagatgg tcagcaagca accaatacca atgcggtggc ctatgcccca tctgataatc
1321 cccaaatcgc tgtcgcagtg gtctttcctc ataataccaa tctaacaaat ggtgtaggac
1381 cttccattgc gcgtgacatt atcaatctgt atcaaaaata ccatccaatg aactagaaag
1441 gaagccatgc tttat
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