GenBank-Updates@genbank.bio.net (08/17/90)
LOCUS STRPBP2BB 1455 bp ds-DNA BCT 17-AUG-1990
DEFINITION S.oralis penicillin-binding protein 2B (penA) gene, 5' end.
ACCESSION M32227
KEYWORDS penicillin-binding protein 2B.
SOURCE S.oralis (strain 3626-penicillin resistant) DNA.
ORGANISM Streptococcus oralis
Prokaryota; Bacteria; Firmicutes; Gram-positive cocci;
Streptococcaceae.
REFERENCE 1 (bases 1 to 1455)
AUTHORS Dowson,C.G., Hutchison,A., Woodford,N., Johnson,A.P.,
George,R.C. and Spratt,B.G.
TITLE Penicillin-resistant viridans streptococci have obtained altered
penicillin-binding protein genes from penicillin-resistant strains
of Streptococcus pneumoniae
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 5858-5862 (1990)
STANDARD full staff_entry
COMMENT Draft entry and computer-readable sequence [1] kindly submitted by
B.G. Spratt, 16-FEB-1990, for release after publication.
FEATURES from to/span description
pept < 1 1436 penicillin-binding protein 2B (penA) (AA at 3)
site 549 551 residue acylated by penicillin
BASE COUNT 429 a 292 c 322 g 412 t
ORIGIN
1 ctgttattgc ctctatttca aaggagatgc ctggcattag tatttctact tcttgggata
61 gaaaggtttt ggaaacttcc ctttcttcta tagtagggag tgtatccagt gaaaaagccg
121 gtctcccagc ggaagaagca gaatcctatc ttaaaaaagg ctattctcta aatgaccgtg
181 ttggaacctc ttatttggaa aagcaatatg aagagacctt acaaggaaaa cgctcggtaa
241 aagaaatcca tctggataaa tatggcaata tggaaagcgt ggacacaatt gaggaaggta
301 gtaaaggaaa caatatcaag ctgaccattg atttggcctt ccaagatagc gtggatgctt
361 tgctgaaaag ttatttcaat tccgagctag gaaatggtgg agccaagtat tctgagggtg
421 tgtatgcagt cgcccttaac ccaaaaacag gtgctgtttt gtctatgtca gggattaaac
481 atgacttgaa aacgggagag ttgactcctg attccttggg aacggtaacc aatgtctttg
541 tcccaggttc ggttgttaag gccgctacca tcagctcagg ttgggaaaat ggtgttttat
601 caggaaacca aaccttaaca gatcagccta ttgttttcca aggttcagct ccaatttatt
661 cttggtataa attggcatat ggatcttttc ctattacagc tgtggaagcc ttggagtatt
721 catccaatgc ttacatggtt caaaccgctc ttggaatcat gggccagacc tatcaaccca
781 atatgtttgt cggcaccagc aatctagagt ctgctatggg gaaattgcgt tcaacctttg
841 gtgaatatgg tttgggttct gcgactggga ttgacctacc agatgaatct actggatttg
901 ttcccaaaga gtatagcttt gcaaatttca tcaccaatgc ttttggccag tttgataact
961 acacaccgat gcaattagcc cagtacgttg caactattgc taacaatggt gttcgtctag
1021 ctccacatat tgttgacggg atatacggca acaatgataa gggtggcctt ggggacttaa
1081 tccaagaact agataccaag gaaatcaata aggtcaatat ttctgaatca gatatggcaa
1141 tcttgcacca aggattttac caagtatcgc atggaactag tccccttacg acaggacggg
1201 cgttttcaga tggcgccact gtttctatca gtggtaagac cggtacaggt gaaagctatg
1261 tagctggtgg tcaagaagct aataatacca atgccgtggc ctatgctcca acagaaaatc
1321 ctcaaattgc agttgcagta gtctttcctc ataataccaa tttaaccaaa aatgttgggc
1381 cagcaattgc tcgcgacatt atcaatttat ataaccaaca ccatccaatg aattagaaag
1441 gaagccatgc tttat
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