GenBank-Updates@genbank.bio.net (08/18/90)
LOCUS HUMC21DLA 2716 bp ds-DNA PRI 18-AUG-1990
DEFINITION Human chromosome 21 distal long arm DNA.
ACCESSION M22486 J04504
KEYWORDS chromosome 21.
SOURCE Human (hybrid cell line WA-17) DNA, clone pPW231C.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2716)
AUTHORS Wong,C., Kazazian,H.H.Jr., Stetten,G., Earnshaw,W.C.,
Van Keuren,M.L. and Antonarakis,S.E.
TITLE Molecular mechanism in the formation of a human ring chromosome 21
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 86, 1914-1918 (1989)
STANDARD full staff_review
COMMENT Draft entry and computer-readable sequence [1] kindly submitted by
S.E.Antonarakis, 10-FEB-1989.
BASE COUNT 813 a 561 c 527 g 808 t 7 others
ORIGIN Chromosome 21q22.3.
1 gaattcagga atataatgca tcattcagta acttcagtaa tccccatcct gggggagcca
61 cagaacgggg gtgagaaatc acagaattac gacaaggtgt ctgggaactc aggtgtccaa
121 caagcattgt ctgaaatctg aacaaatctg attgactgtt ttgcaataaa tatgtaggtg
181 ctattaaggc tagcaaaacc ccaattgcct taaaagggtc aataatttat ttataacacc
241 tatttgacaa tagttatttt ctcaaccaac aaataccaac ctatcccatg agtcttcaag
301 atgtgttgac attacaaagg accctcattc caaaacactg ggaacccctg atccaagcag
361 tctgtgtcct gggaggtgaa gatatggggg tcacctcagc agggcctggg gaaaggctct
421 ttgaggggag gggcttctca cctgcttttg tacaggcagt ggggtggcag tgggacttag
481 gtaagtgggc agtgagtggg cagggcaatt ccccaaaggg aagagactgc ggaggtgtgg
541 gggaagaaac agtctgccct cagcttttgt tgcgtcctcc ctgcactttc ttactagcag
601 ctggaggtca gaaaaggcat tcaccagcaa ttttgcttcc ctaacatctt ttatattgaa
661 gtcactctga cttagagagc atcctacatt ttagtcactg acccataaag tacaaatgaa
721 agctggtaaa aggataacaa tcagcattct gaataactcg ctgggaaatg cctcaaactt
781 gaaggatgtt ttaataataa ttcaccaatc aattccatta gtcttaaaga tgagacaagt
841 acaaagagaa aatttgaatt acacagctcc tcttgctaca atttaaagct attttgagct
901 aagtttaaac cttttgaaat gtagtatctt gctgtctttc agccagaaaa atgcaagata
961 ctaatagtaa aacccaatta ataataaact atatttctgt gcttcacatt tttgctcaag
1021 tgatatgccc tttatatctc aatgccatat tttaacagct ctctttattc aaaaaaccat
1081 gccaagcaaa ggtaatttaa actgctttta tcatgcaacc ttaacaccta ggtttttaaa
1141 aataaggatt tcttaaaaag tttttcatcc actgtagcct ttttttagtc actatctctc
1201 ttaacatact tatttgttct actcgtgctt tacctaatcc tagcatgctc tgctaatgaa
1261 tttatttgtt tctgatcact ttttcaaatg acagttttgt ttttttgttt gggggatttt
1321 gtttggggtt ttttgcatat atattaattt cctgaggctg ccatattaaa ctgtcatatc
1381 aaacatattc tataccacaa acttggaggc ttaaacaacg gaaatttatg gcctaacagc
1441 tctggaggtc agaagtccaa gatgaagggt cagccaggtt ggttcttctg aggactgtga
1501 ggggaaatct gttccttgcc tctgccttag cttctggtgg tttgcaggca acctgacatt
1561 ccttggtttg tagctgtatc atctccatct ctgccttcat cttcccatgg cattcttcct
1621 gtgtgtatgt ctttgtccaa atttctcctt tttgtaaagg caacagtcat cttggattag
1681 gggcccaccc tactccagta tgactttatc ttaactaact acatctgcaa tgaacctatt
1741 tccaaataag gttacattct gaggtcctag aggttagaac tccaacatat gaatttcaga
1801 gtgaaggagg aacatgattc aacgcataac agcttgtaac attgtgtaca gaaggtgcaa
1861 cttttttttt ttattctact tcaagtttta gggtacatgt gcacattgtg caggttagtt
1921 acatatgtat acatgtgcca tgctggtacg ctgcacccac taactcgtca tctagcatta
1981 ggtatatctc ccaatgctat ccctcccccc tccccccacc cctcagagaa ctgcaaatca
2041 aaaccactat gagataccat ctcacaccag ttagaatggc gatcattaaa aagtcaggaa
2101 acaacaggtg ctggagagga tgtggagaaa taggaacact tttacactgt tggtgggact
2161 gtaaactagt tcaaccattg tggaagacag tgtggcaatt cctcaaggat ctagaactag
2221 aaataccatt tgacccagcc atcccattac tgggtatata cccaaatgac tataaatcat
2281 gctgctataa agacacangc acacatgttt attgcggcat tattnacaan angcaaagac
2341 ttgggaccaa ncccnaaatg tccaacaatg atagactgga ttaagaaaaa tgtggcacat
2401 atacaccatg gaatactatt gcagccataa aaaatgatgg gttcatgtcc tttgtaggga
2461 catggatgaa attggaaatc atcattctca gtaaactatc gcaagaacaa aaaaccaaac
2521 gccgcatatt ctcactcata ggtgggaatt gaacaatgag atcacatgga cacaggaagg
2581 ggaatatcac actctgaagg tgcaactttt aaatgctgtg tttgaatggt ttcctactta
2641 ttgacggacc catcatgtat acgaattaag gtttaggatc ttgtaaccaa gccttcttga
2701 gattctnctt gccatt
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