GenBank-Updates@genbank.bio.net (08/18/90)
LOCUS HUMR21A 2132 bp ds-DNA PRI 18-AUG-1990
DEFINITION Human ring chromosome 21 [r(21)] breakpoint DNA.
ACCESSION M22485 J04504
KEYWORDS chromosome 21; ring chromosome; ring chromosome 21.
SOURCE Human (genomic library) DNA, clone lambda-21BP.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2132)
AUTHORS Wong,C., Kazazian,H.H.Jr., Stetten,G., Earnshaw,W.C.,
Van Keuren,M.L. and Antonarakis,S.E.
TITLE Molecular mechanism in the formation of a human ring chromosome 21
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 86, 1914-1918 (1989)
STANDARD full staff_review
COMMENT Draft entry and computer-readable sequence [1] kindly submitted by
S.E.Antonarakis, 10-FEB-1989.
BASE COUNT 515 a 554 c 570 g 493 t
ORIGIN Unreported.
1 gaattcagga atataatgca tcattcagta acttcagtaa tccccatcct gggggagcca
61 cagaacgggg gtgagaaatc acagaattac gacaaggtgt ctgggaactc aggtgtccaa
121 caagcattgt ctgaaatctg aacaaatctg attgactgtt ttgcaataaa tatgtaggtg
181 ctattaaggc tagcaaaacc ccaattgcct taaaagggtc aataatttat ttataacacc
241 tatttgacaa tagttatttt ctcaaccaac aaataccaac ctatcccatg agtcttcaag
301 atgtgttgac attacaaagg accctcattc caaaacactg ggaacccctg atccaagcag
361 tctgtgtcct gggaggtgaa gatatggggg tcacctcagc agggcctggg gaaaggctct
421 ttgaggggag gggcttctca cctgcttttg tacaggcagt ggggtggcag tgggacttag
481 gtaagtgggc agtgagtggg cagggcaatt ccccaaaggg aagagactgc ggaggtgtgg
541 gggaagaaac agtctgccct cagcttttgt tgtgtcctcc ctgcactttc ttactagcag
601 ctggaggtca gaaaagggtg tttgttcagg gctgcttgag tgggtaacga gctgaacctc
661 tctgaacatg gcttcctctt cacagcctca gaccatgacc tggctcactc ccctcctggc
721 cagccaagac cggccattga aataacagcc cccagagcca agctgacgct ggcccaaggc
781 actggctgtg tgttctgcgc gcgcacctgt cgggccagcg cctccagtaa ggaaaagaga
841 cttgctccgt ggagcttcca atgtgttttg gggtgggagg tagggatttg gagaggaagt
901 tggatcacct aaaatgctga caaacagacg tacctttgca caaacaatgc caacatgctg
961 gcaggattaa agtcattctt gttgctgtga aaccattttg attatataaa taaaatagtg
1021 catccccatt gctgacctcc aagataagga aagcttgccc cacatccata aaataagaat
1081 attcttttga actagccaca cctagaggct ggtgtcaggg ctcctgaggg gccctactgg
1141 aatcacaagc catcctagcc ggcttctgtg ccctcattcc tgatgcagcc tcttcctggg
1201 gggataattg agaaaaccca acgcggatca ggccctggtc tccattggct ccctgacctc
1261 gcagcaggct actatcctga gtcttaagct cagtggcacc agtagcttta cctccaacag
1321 ccagaccccg ctcccagttt caatccttgc tcctccccat ggcttccagg atggacccaa
1381 gctccggaga gatgtgcgaa gccctcccag ctctggcctg ctggctccca ggcacgacca
1441 cacacacacc ctctctcctg ccacccccag gcctccctcc agctccccta gccaggcttc
1501 cctagctggt gtcccaggag cccggccact tcatctgtgc cgctgctgtt gcacaagttc
1561 ctgccccccg tgctcctggt ggacacaccc tagcctttgc attccatgtt catctacccc
1621 ttggtcactc cacaactctt tgtggccctg ccctggggtg ggtgctgggg ggtattgaag
1681 aagacagagg ttctggggtc tcatgaggct tattgatcta ttctactaga gagaagctga
1741 acagttatgc atgttgctat ttagtgacaa ctggtatcag cgctacctcg gaaaagaagg
1801 ctgaatgcag gaagaggatg ccaggctggg gcactgagga agaggtggcg tgtggcccgc
1861 gggaaggcat gaggggctgt ccttctggaa caggaagtag aacattctga agggcatgtc
1921 acacgttctt caagctcact ctgccagcca ctggagaatg gacgtaatgg agccaaggat
1981 ggcaccagga agtcacgggg gcatgtttgc tgctgtccag gtaggagatg gtgatgggtg
2041 ccctgtcccg gggggaagtt gtggaggctg atccaagtgc acagaacaac tctgagctgt
2101 aggagaggaa gggggcatat ccttcagaat tc
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