GenBank-Updates@genbank.bio.net (08/21/90)
LOCUS HUMCRYGBC 22775 bp ds-DNA PRI 21-AUG-1990
DEFINITION Human gamma-B-crystallin (gamma 1-2) and gamma-C-crystallin (gamma
2-1) genes, complete cds.
ACCESSION M19364 M19365 M19354
KEYWORDS .
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (sites)
AUTHORS den Dunnen,J.T., van Neck,J.W., Cremers,F.P.M., Lubsen,N.H. and
Schoenmakers,J.G.G.
TITLE Nucleotide sequence of the rat gamma-crystallin gene region and
comparison with an orthologous human region
JOURNAL Gene 87, 225-232 (1990)
STANDARD full staff_entry
REFERENCE 2 (bases 1 to 22775; for [1])
AUTHORS den Dunnen,J.T., van Neck,J.W., Cremers,F.P.M., Lubsen,N.H. and
Schoenmakers,J.G.G.
JOURNAL Unpublished (1988)
STANDARD full staff_entry
COMMENT Submitted in computer readable form by J.G.G. Schoenmakers
23-MAY-1988
FEATURES from to/span description
pept 2152 2160 gamma-B-crystallin, exon 1
2255 2497 gamma-B-crystallin, exon 2
5313 5588 gamma-B-crystallin, exon 3
pept 18410 18418 gamma-C-crystallin, exon 1
18519 18761 gamma-C-crystallin, exon 2
19723 19995 gamma-C-crystallin, exon 3
pre-msg 2116 5653 CRY-gamma-B mRNA+introns
IVS 2161 2254 CRY-gamma-B intron A
IVS 2498 5312 CRY-gamma-B intron B
pre-msg 18374 20060 CRY-gamma-C mRNA+introns
IVS 18419 18518 CRY-gamma-C intron A
IVS 18762 19722 CRY-gamma-C intron B
BASE COUNT 6513 a 4984 c 5205 g 5948 t 125 others
ORIGIN
1 ctgcagttat ctcagcttta ttttcttctt gtagtggacg ctctggtgct gcctggactt
61 ccactgtgga ctgaagcact ccttctccca gatagctgac ngcttaaagc tgagtttgtc
121 tccaagaatt ttcttctgct ggaggaagct gccttgccca aagttacact tctccatngc
181 agcagcccac atcaaattac ggggcaatgc agaggcacag attcccggtc cacttgccta
241 agttcctgac aactctagcc ctagccttnt gcgggatggg atgaagtcac cattattgca
301 ataggctctc tctcagctca cacttacaac tgcctgcagg ggtcccttct gaccagctga
361 tagagtgggg gaaggctgag cttgatacac taataaattg gcatggcatt tgggtacaag
421 cccaaaatag aatgctgctg cagaatagct cactcaggag tcaccctaaa gacagcagtg
481 agggaaatcc tcccaaaagg caaccttgag gtagtgcacc tggctgctca ctcggtgcag
541 aaagaaaagt agcccaaggt caagcatata tggaattatt gagcagtaat gtgtggcttg
601 gctggctggt ccagggcctg gaaggagaaa gattggaaga ttagggacaa gaaggtctgg
661 ggataggaat gtgcagggag atatgggatt gggcacaaag ggcgaagata gttgtatccc
721 atgtgaaggc ccagtgtagg gcatccacca ttgaagaggc actaaacaac caagtagaaa
781 aaatgatttg gtcatttgat tccagtcagc gtctgccatc agccacccta ctgctggcag
841 tgagctcact aagagagcgt tcatagtggt atggatgaag gctatgcatt aacttctact
901 tattaaggct aatccagcta tttccactgt agaatgtcca atctgccagc aatagggacc
961 aactctgagc ccttttggtc ccatgccttg agaagaccaa tcagccactt agtggtaaca
1021 tttgaggcag agcaggaaca ccaaacagca ggcaggactc tggacagcca ccagcagaag
1081 gagggattag gcccttagga agatctgaaa gggggaagaa agccacaact ctctgttttt
1141 gctcaggtca gagccaatta ttgaggacct gcaatgtgcc aaccctctgc tctagggctc
1201 agggatagac atgaacaaga aataataccc agcccccaga agcctacaaa ttccaggcaa
1261 gtatcagttt tattcaagac aagcccccaa acaccaacaa tgatgatcac agaatttttt
1321 tttttttttt ttttgcgaca gggtcttgct ctgttgccca ggctggagtg cagtggtgca
1381 atcatggctc actgcaacct cgacctcctg agcttaagcg atcctctcac ctcagcctcc
1441 caaatagctg ggactacagg tatgcgccac catgccgggc taatttttgt atttgttgta
1501 gagatggggt ctcaccatgt tacctaggct ggtctctaac tcctgagctc aagcaatcca
1561 cctgcctcag cctcccaaag tcctgggatt ataggtgtgc accacctcgc ctggctgatc
1621 acagaatttt gaatttgaac taagctttat gggttttaac acactttcac agattacttc
1681 acttgattcc ctcttcttta agattcctta ctatttaaat tctggctttt agaactaaaa
1741 cacacacaca cacacacaaa aacaccacca gtccctgagc agaattcatt acttagttta
1801 atgacttttg agaagtcaat taagcagagt aaactataaa ataaaagcac agagacagaa
1861 tttcgcccgt ccttttgctc aactaaaagt gtactctatt cattttgatg gcaacaacag
1921 ctttagtgaa ttagaacaac ccgaacctac cagaaagaat gagagtaaac cattcagcca
1981 acccagtgac ctgggcacgg agagcagcga gcttgcaaat ccccttactc accaaaatgg
2041 gcccttttgt gtgatttcct gtggaggcag cagtcagggc tgctatacat acagtgacgt
2101 tcctgcagtt cccacacagc aaccagaaaa catctgctca cttccttcaa aatgggaaag
2161 gtaagtcctg ggtaccggat gctcagcctt ggccctaatg cagtggcctc agtgggggca
2221 atcactccat gctcccacat cttccatttt tcagatcacc ttctacgagg acagggcctt
2281 ccagggccgc agctacgaat gcaccactga ctgccccaac ctacaaccct atttcagccg
2341 ctgcaactcc atcagggtgg agagcggctg ctggatgatc tatgagcgcc ccaactacca
2401 gggccaccag tacttcctgc ggcgtgggga gtaccccgac taccagcaat ggatgggcct
2461 cagcgactcc atccgctcct gctgcctcat ccccccggtg agtgtggctc tgtctttgcc
2521 ttccatcttt ttggaaataa aagctatttc atgatattct tttttttttt tttttttttt
2581 ttgaggcgga gtctcgctct gtccccaggg tgagtgcagt ggcatgatct cggctcactg
2641 caacttccgc tcccgggttc aagcaattcc cctgcctcag cctcctgagt agttgggatt
2701 acaggcatgc accaccatgc ccggccaatt tttgtattca tagtagagac gaggttgcac
2761 catgttgccc aggctgatct cgaactcctg gcctcaagtg atccgcccgc ctcggcctcc
2821 caaagtgctg ggattacagg tgtgaactac ggcatccggc ctatttaatc acattattct
2881 taaatcccag ctactcgggc ggctggggca ggagaattgc ttgcttgaag ccgggagatg
2941 gaggttgcag tgagccgaga tcgtgccact gcactccagc ctggcgacag agtgagactc
3001 catctcaaaa cgacaacaat aacaacaaca acaacaacaa caacaacaaa cttttgcttg
3061 ctttgtctta cttttctatt tgattattcc tcctgagaag ataggatcct gtcttctgat
3121 ttctattcta atttaatggt cagtacctat tagctcactt agaggtataa attagagaaa
3181 aggccaaatc tgaaactaaa gtttgagatt ccatattttc tgggcagtac tgcagaattc
3241 ttagaattgt ggtgtgtggg aggcatggga tacagtgtca taaaaacaga agttaatgaa
3301 ggtgatactt cctgctgagg gaaataaata agttgagagc aggaggctag aaaggaagct
3361 taaaagtcag ataggttgaa atttgaactg aaggctgggt gcggtggctc acgcctgtaa
3421 tcccagcact ttgggaggcc gaggtcagga ggtcaggagt tcaagaccac cctggccaat
3481 atggtgaaac cccctctcta ctaaaaatac aaaaattagc tgggcttggt ggcacgcgcc
3541 tgtagtctca gctacttggg aggctgaggc aggagaatcg cttgaacccg ggaaggtagg
3601 ttgcaatgag ctgagatcat gccactgcac tccagtctgg gtgacagagc aagattccgt
3661 ctcaaaaaaa aaaaaaaaag aaaagaaatt tgaactgaaa attagccaga tgtggtggtg
3721 catgcctgta gttccagcta ctcaggaggc tgaggtggga gggtcacttg agcccagaag
3781 gttgaggggg ctgtgaccca tgatcatgcc attgcactcc agcctaggtg acagagggag
3841 accctgtctc aagaaacaaa tacatatatg tgtgtgtgtg tgtgtgcgtg tgcatataat
3901 agtgaacccc aaatatctga gacaggtctc agtcaattta gaaagtttat tttgccaagg
3961 ctgggcacag tggctcatgc ctgtaatccc agcacttttg ggaggccaaa gcaggcagat
4021 cacctgaggt ccggagtttg agaccagcct gaccaacatg gagaaacctc tactaaaaat
4081 acaaaattag ctgggcgtgg tggcgcgtgc ctgtaatccc agctacttgg gaggctgagg
4141 caggagaatt gcttgaactt gggtggcaga ggttgtggtg agccgagatc acgccattgc
4201 actccagcct gggcaacaag agtgaaactc catctcaaaa aaaaaaaaaa aaaaacccag
4261 aaagaaggtt tattttgcca aggttgagga atgcacccat gacacagcct cagaaagtcc
4321 tgagacatgt gcccaaagtg gtcaggggta cagtttgctt ttatacattt tagggagaca
4381 tgagacatca atcaatacgt ataagttgta aattggttca gtctggtaag acaggaagta
4441 ggggcttcct ggttagacat ggataagaaa cagagctggg cacgtggctc acccctgtga
4501 tcccagcact ttgggaggct agaggtgggt ggatcgcctc aactcctgac agagtttaag
4561 accagcctgg ccaacatagt caaagcccgt ctctactaaa aatacaaaat attagctaat
4621 cgtggtggtg ggcgcctgta atcccgctac ccgggaggaa tcacttgaac ccagaaggtg
4681 gaggttgcag tgagctgaga ttgcgccatt aaaaaaacag tagataagag acaaaaggtt
4741 ctttgagccc ttgatcagct ttccactgaa tacacaattt agtctggctc gatgactctg
4801 catctttaca taaacaatag gggagaggaa gcaatcagag atgcatttgt ctcaggtgag
4861 cctcagaggg atgactttga atagaatggg agacaggttt gccctaagca gttcctggct
4921 tgacttttcc ctttagctta gtgattttga ggtcccaaga tttattttcc tttcactgta
4981 tatacataat atgacattta actttccaat gactctcagt tttctccttt gagaaaggct
5041 ttctcaaata acaggcacta aagtgatgtg atattttatt gtaagcaaat cttaattccc
5101 aaagccctag ctctgcccat gaatcattag actcagcggt gggtgactgg ggagtgtgac
5161 agccccttaa ctttgcaaca gggttgttct agaagcaaac ttggcctggg agaacttctg
5221 ggcaggtgtg gccagggagg tgtagggact ggagctttaa tttccatctg tttttgtttg
5281 tttactcttg cgttttctgt ctgccactcc agcactctgg cgcttacaga atgaagatct
5341 acgacagaga tgaattgagg ggacaaatgt cagagctcac agacgactgt ctctctgttc
5401 aggaccgctt ccacctcact gaaattcact ccctcaatgt gctggagggc agctggatcc
5461 tctatgagat gcccaactac agggggaggc agtatctgct gaggccgggg gagtacagga
5521 ggtttcttga ttggggggct ccaaatgcca aagttggctc tcttagacga gtcatggatt
5581 tgtactgaag tatttacgtt ttccactttt ctcctttaaa atctaataaa atatttagct
5641 tgtgtttctg gcactagtag agccctgtct ttctttcaat ctattaagca tttataagtg
5701 ataatggcac tcagccaaac ataataacat gttttcatga tgggaagcaa tcttttataa
5761 ggggaataat gcagagatat tatttccagc actcttgtaa tgactaaaac actgtaggct
5821 caaataaaag ctcagttcac ttggactcag gccaattgta gttagtctca ccaggctaga
5881 tttgcagcta cggtggtgaa ttggtacttt ttgaaacacc tccaagttat ccctccaggt
5941 tatccctatt gtcttcccta atagtccagg ccttagctga tgaggaaagt tgttctcagc
6001 ctctagactc ctacctcagc tccataaaca aacaaataaa tgaactggtc cactcttacc
6061 tattgcactc ctgtcctcct aacagtcacc atccctttcc tctcacttcc actgccaata
6121 tctcattcca ctatgagatt tccagtccaa atagaattca ctgtgttttc gctatatgtg
6181 ctttgtggaa taatttcagg acatttacaa aaaccacatg cgcacgggaa gctcagcctc
6241 atgtcatttc agtagagagt aaaatattat gattacacat aataatacta agtggccggg
6301 cgtggtggct cacacctgta atcccagccc tgtaaacctg cgtctccagg gctcaagcga
6361 tcctcccacc tcagcctccc aaatagctgg gattacaggc gcacaccacc atgctcagct
6421 aatttttttt atttctagta gagacagggt cttgccatgt tgcccaggct ggtctcaaac
6481 tcctgagctc aagcgatcct cttgtctggg cctcccaaag tgccagaatt acaggtgtga
6541 gccaccacac ccagtcataa actcggtcat ttgttttgat tttgggtttt tttttttttt
6601 tttttttgag atggagtctc actctgtcac ccaggcggga gttcagtggt gcaatctcag
6661 ctcactgcaa cctctgcctc ccagttcaag cagttctcct gcttcagcct cccaagtagc
6721 cagaactaca ggcgtgtgcc accacgcccg gctaatgttt gtatttttag tagagacaga
6781 gtttcaccat gttggccagg ctggtctcaa actcctgacc tcaggtgatc cacccacctc
6841 ggcctcccaa agtgctggga ttacaggagt gagccaccac gcctggccta cactgggtca
6901 tttttgagag tgaaagtata tactattaat aattacactg ggacaagaga catgaaccag
6961 gactgttcta ggcaaacttg gatgcaagtt taccctactg tgtgtgtgtg tgtgtgtgct
7021 aaatattact acaaaagtgt caaaaaggtt taaaatgtta aaaagtttat gttacaaagt
7081 tacagtatgc taatgttagt ttattattga agaaagcaag cattttaaaa aaatgtgtag
7141 cctaagttta gcctactgta tgtatatgta tattagccta ctgtatgtgt gtatatatag
7201 agaacacaaa tacatataaa gatttatttc ctgaaaaaca gtcagaatct aggattattt
7261 agtgttaact cttcctaaat cttgggtctt taacctttaa actcgcaaca atagtgatgg
7321 cttcctggag ctattaatca gagtcctctg tttgtcaaca ataatatgtc aaacataatt
7381 cagaaaacca aaagcttctt aacgtgctga atttttacac tatttcctag aagacataaa
7441 atcacatatt ttggctgggt gcagtggctc acgcctgtaa tcccaacatt ttggaaggcc
7501 aagacaggcg gatcacttga ggccaggagt ttgagaccag cctgaccaac atgccgaaac
7561 cccgtctcta ctaaatttaa atacaaaaat tagctgcacg tggtgacaca tgcctgtaat
7621 cccagctact acagaagctg aagcacgaga atcgcttgaa cctgggaggc ggaggttgca
7681 gtgaggtgag atcacgtcac tgcactccag cctgggcaac agagagagac tctatctcta
7741 aaaataaaaa taaaagtaaa tcaccgtctt taggcatgaa aattattcta aaacatctga
7801 actgaaaggg attagagtcc ccgaatctct ttgatcaagt cattattctt agaaattttt
7861 tgctcctatc cctgggatac aggcaaagaa aaagatgtcc tgtcctcctc ctaaatccaa
7921 cataaagaga aagtcaatac tcaggtggtc cgcctgcctc ggcctcccaa agtgctggga
7981 ttatagtgtg agccaccgtg cccagcttgc tatactatac tttttatcat cactttagag
8041 tattctcctt ctacttatac ttttttaaaa aaaaaaaagt taactgtaaa cangcttcag
8101 cagagccttc aggaggtact acagaaggaa gcatcatcat cataggtgac agttccatgt
8161 gtgtttttgc ccgtgaagat cttccagtgg tacaacatgt ggaagtggta gacagtgata
8221 ttgatgatcc tgaccccgtg taggcctaaa ctaatgtgtg tgtttgtgtc ttagtttttc
8281 acaaaatttt aaaaagtaaa agaataggcc aggcgtagtg gctcacgcct gtaatcccaa
8341 cacgttggga ggtcgaggca ggcagatcac ttgagcccag cagtgtaagg ttcttgtatc
8401 agttccaacc ccaagagcgc gtccacagac aacacgagga ggtgtggagc aataagctgt
8461 tttaaggagc gcctgggtgc gcctgagtgc aggaaggccg aggcttaaaa tggcgtcagc
8521 accaagtgag gacggggcaa aggttttaca gtctcctgta aacaggaagt gtcctagtct
8581 gacgtaactg ctacgttgta cccggatggc ctctttctcg atcttcgggg gtacgtgtct
8641 tccagccggc tctcttcctg cttctgctat cctgctggcg cacactgctg acacaagtga
8701 ccttgcgcct tgggactggg cctgggaagg gaggggttac tcatcccctt aagctttcag
8761 actctgggga gaatcataca aggagtttga gaccaccctg ggcaacatag caaaacgcca
8821 tctctattaa aaaaaaaaaa aagaaaaaag tttatatagt aaggataaaa agaaaatatt
8881 tttgtacagc tatacaatgt ttgtgtttta agctaccaca aaggtgtcaa aaaggcttaa
8941 aatgttaaaa agtttataaa gttacaaagt tacagtatgc taatgttagt ttattattga
9001 agaaagaaaa gcattttaaa aaaatgttgt gtaccctaag tgcacagtgt gtataaagtc
9061 tacagtggtg tacagtaatg tcctaggcct tcacattcat tcaccctcct cactgactca
9121 cccagagcaa cttccagtcc tgcaagctcc attcaatggt aagtgtccta tacaggtgta
9181 caatcttttt tttttttttt ttgagacagn gtatcactct gtcacccagg ctggagngca
9241 gtggtgtgat cgcggctaac cgcaagctct gcctcctggg ttcatgccat tctcctgcct
9301 cagcctcccg agtggctggg actacaggca cccaccacca cgcccagcta atttttttgt
9361 atttttagta gagacggggt ttcaccgtgt tagccagaat ggtctctatc tcctgacctc
9421 gtgatccgcc ttgccttggc ctcccaaagt gctgagatta cangcgtcag ccactgtgcc
9481 tggccaggtg tacagttttt taatcattta taccatattt cttgttggga acaggccccc
9541 ccaaatctgc cataaactgg ccccaaaact agccataaac aaaatctctg cagcactgtg
9601 acatgttcat gagggccata acgcccacgc tggaaggttg tgggtttact ggaatgagga
9661 caaggaacac ctggcccacc caggtcggaa aaccgcttaa aggcgttctt aaaccatgaa
9721 caatagcatg agcaatctgt gccttaaggg catgttcctg ctgcagataa ctagccagac
9781 ccaccccttc atttcggccc atcccttctt ttcccataag ggatactttt agttaatcga
9841 gtatctatag aaacaatgct aatgactggc ttgctgttaa taaatacatg ggtaatctct
9901 gtttggggct ctcagctctg aaggctgtga ggccctgatt tcccacttta cacctctata
9961 tttctgtgtg tgtgtcttta attcctctag tgccactggg ttaggctgtc cccagtcgag
10021 ctggtctcgc atttctactg taccttttct atgtttagat ttgtttagat acacaaatac
10081 tagtgtagta ggctgatcca tctaggtttg tgttagtaca ctctatgatg ttcacacaac
10141 aatgaaattt ctcaaaatgt atcccattga taagagatgc atgggggaag aggaggctag
10201 agaatgtagg catgggccgg gcgtagtggc ttactcctgt aatcccagca atttgggagc
10261 ccgaggcggg aggattgctt gagcccagga gctcgagacc agcctgggca acatagtgag
10321 acctcatctc tacaaaaaat aaacaaaatt agccgggcat ggtagcaggc acctgtggtc
10381 ccaaattctt gggaagctga agtgggagaa tcccctgagc cagagagata gaggctgcag
10441 tgatccaaga tcagccactg tgctccagcc tgggcaacag agcgagacct tatctcaaaa
10501 aaataaaaat aaaaagagct agagaatgga ggtgcaagtc agtagcggtg gtgcaggcga
10561 gcttgcagcc caagaccctg cctctgccct cagcaaggcc cctggcaggc aacgactgca
10621 agctgcatgg tgagggccca ggtcataagg aatgggcaca tctggatgtg agagtggggt
10681 tgaaaaatat aggccagtaa agctgaatga aaatgacagg aatgaataca ctgtgggcag
10741 gctggagatc tttgcaagag aagggaatat gcctcacatc atctttgctg gcccctggaa
10801 ctgacaaagt tataagcatc ctgggcccag cactgaagga tgccatgctg gaactcagtg
10861 cttcaaatgg caagggcatt gacgttgcga ggaataaaat caaaatgttt gcttgacaaa
10921 aagtcatcct tcccaaaggt caacataaga tcatcttcct ggatgaagca gacagcataa
10981 ctgatggagt ccagcaagcc ttcaggggaa ccattgaaat ctgctctaaa acgactcact
11041 gtgttcttgc ttttaatgct tcagataaga tcaccggaag gcccatgtga cagcagcata
11101 gatgaaggat cagagagagg ccaaattggg gtttggacat catgaagaag ctgttgtagt
11161 agtctaagga gaagaaaaag gagagtttta gaattctaca tttgtctgac tggtggttct
11221 tagctccagc tgcaggcagc acctccagtg gagctttaaa gaaactgtga gtgtcctgtt
11281 cctaccccca gccagaccga attgtcatct gcccagaagn nnccaacgcc cagcatacat
11341 tgtgattcca gagtcttcct gggcctgaat tgactcactg agggcttgtg gcacatggat
11401 gtctgccttg gaggatcatt tctccatctg aaaagccctg gccagccaag gccattgctg
11461 gggcagtgct ggctgaggcc tctgtctgat ttgcacttca actgggtgat ttggggaagg
11521 atcttaaaaa gctggagttc actctagatt agatgttagc agaaagcagg gttaattttg
11581 tgattagtta tctcaaggaa tcttacccat ggggagggga gactagaaca cggataaacc
11641 tgtaatccat aaagaagtag cagttaatca ttttggctga gagagagagg gcttggaatt
11701 ttgagagtgg agcattgact ttgtttttgt ctgcgcttag acaaagttaa gaagtggctt
11761 tattttatct catttcatcc tggtctcgga gtagccttgt ctgaagttgt tattctgtga
11821 gattgtttat gtctaatagg ggagtaacat gtcctcactg tgagtgccag gccagcatct
11881 gaatgtcaga gcctgctctt ttttctcact ttttttctca ttaatcagac tacagtccat
11941 agagataact catgctctgt gtggttatgt aatttgccat ggagctaatc agtgggcctt
12001 ctgagtgtag gcggcctgag tccaaagctc acactcttgc ccgtgaagct ttatagcctc
12061 cctcatgctt ggaaaaggaa aagcaattta taaagcaata ctttatactt tggttaatac
12121 tttgacattt agccttgttt ttactgcatt tctcttaagc acctgctgcc aaagaggagt
12181 cgcaccacca gcatggctgg gctttgtgga ttatgcagct gcatcctcgt aatcaaagca
12241 ctaatagggt gatgccagcc tctgagggaa acctcactgc cttcccgtct ctgttcagag
12301 gccactggat cccagtgcat agtcctccgc tacacaaagc tgaccgatgc ccggagcagt
12361 gtgaggccga tgaatgctag agagaagggt acagttctgt acactgactt tggcctagaa
12421 gccatcatcc tcatgggtca gggagacatg agacaggccc tgaacaactt gcagtccatc
12481 ttcccaggat ctggcttcag ttacagcgag aagtatgttc agggtctgtg acgagcccca
12541 ccccctgctc atgaaggaga tgatccagca ctgtgtgaat gcccatgtca aggaaaccta
12601 caagattcct gctcacctat ggcatctggg ctactcacca gaagatgtca ttggcaacat
12661 cttccaagtg tgtaaaactt tccaaatggc agaataactg ataaagtgga gtttgtnaag
12721 gaaattggat acactggtat gaaagcagag gaggagtgaa ctcccttctg cagacaacgg
12781 ggctcctggc caggctatgt cagaagacaa tggccccagt ggcatagagc agaggcttta
12841 ttgattgagt tacaagagcc ctaatccctg taatacagga ggtgcagcct tctgaagtgg
12901 agggggaagc gtgggtgggg aatgccacct taagctggtg ccagcataca ccatacttta
12961 aaccctcgtg gttttcacgt tgcttctagc tgatctctgc tccatgagtg tttgcattca
13021 acctcagact cactgacgag tgatggagca gggcagaaag gctcagagaa gctcagggca
13081 ggcacctgat ctgtgtgtga gttgacattt agctcataaa gccttgcagt gtttgttgta
13141 aggtgaccac atgaggcctc aaggaaaacc agcttcctgt ctctgccctt gcttgttcct
13201 cccctttcta cttgtggccc ctagcagcct gcaagtagga agatgactag agagtagatt
13261 ggacaagcta atctcaattc ttctagaagc atgaagggac cagttccctg gggtgagggc
13321 agagtttgct gtaatttatt tagatagact tctcaaaacc aggcaataag ccttcaggaa
13381 gggcttgctg agggggtcga ctggcaaagc accacacaaa aaccccagca tgatgccttt
13441 cccatgtcct cgagggaact cttggccttc gctttagaat tccccagtga attttatatt
13501 aatttgtaga attgcctttt tatttgcaag ggtactattt tttcccattt tttaaaatta
13561 aaattgcaat catataaaaa agagatgcat gactgcatag gataccaccg tatattaatt
13621 gctaagaagc aggaaggtgg gtggtaaaat caactgctgg ctggacctca gacaccagca
13681 aaactctaga attggctacc gctgttgtaa cattaatttc tcatctcaga agaaataaaa
13741 attagaatta ctaaggagtg ggaggactta gggcacaaca cagcattcct ggtttttccc
13801 ttttgcttat tatctccact gttataaagg cccattatgg ctgggtgtgg tggctcacac
13861 ctgtaattcc agcatttggg aggccgaggt gggcagatcc cctgaggtca ggagttcaag
13921 accagcctgg ccaacatggt gaaaccctga ctctactaaa ggtacaaaaa ttagctgggc
13981 gtggtggcag gcgcctgtaa tcccagctac tcgggaggct gaggcaggag aatctcttga
14041 acccaggagg cagaggttgc agtgagccaa gatcgcacca ctgcactcca gcctgggtga
14101 caagagcaag atttcatctc aaaaaaaaaa aaagaaggcc tggcacagtg gctcagtctt
14161 gtaatcccag cactttggga ggccgaggcg ggcggatcac aaggtcagga gatcgagacc
14221 atggtgaaac ctcgtctcta ctaaaaatac aaaaaattag ccgggcgtgg tggcgggcgc
14281 ctgtagtccc agctactcgg agaggctgag gcaggagaat ggcgtgaacc ctggaggcgg
14341 agcttgcagt gaactgagat tgcgccactg cactccagcc tgggcgacac agcgagactc
14401 cgcctcaaaa aaaaaaaaaa agccccatta aatcgatctt gtgcagggtg cctgtgtcat
14461 cctacacacc gaaagttgca catcctgaac ttcaatgtga gtgtgttatg cctgtgtata
14521 ttgaacattt gaaacaggct ccatagacca ttataataat aaatttcaga caaggaataa
14581 caatcacaca tccccccccg ggcatttatt gagtaacctt tatgtgccag tcctctaagc
14641 caattagtga gaacacaaaa ataaagatgg aatagactct gcctttatgg ggctctccca
14701 tctattttga gggactgatg tctaaacaaa ataattagat aagtgatagt tacccttata
14761 gtggtatgaa catgaggagc cacggaggca gtatttaatt cagcccagaa gattaggaag
14821 ggttcaggaa aatcttttac agacaaactg acgcttgagc tgagacttga agaaagggta
14881 aaatttctct ggttgaaaaa taaactggtg tctcattgag aaggatcaat atgttgaaaa
14941 acaagaacaa catgaaataa cattgtgcat ttgggaaatg acaagcggtt cggcgtgatc
15001 aatcagaaag cgtggggaca gacagcggag gccaggtcta ggatgccgcg ctaagggatc
15061 aatattggat cctgagacaa tggagtccag taaattttca agcaaatgaa cagcatgatt
15121 tgatgtgttt tagttctcat cactccagca tctgtctgag tgcagcttgg aggaagacaa
15181 cactgggcag agtcaggagg ctgttgaaag tccagctgag atatgataag accctatgta
15241 aggcagctac aatggcaggg gtttgggggt gggaggtggt tggggnagag gagagaagga
15301 gaaagatttg aaaaaaggtt agagaaatac aagactacgc cattaggaac aagagcgatg
15361 ttctgtaata tgcactttct ggccccttta ttgcttttcc tgtcttctta ccagtgctct
15421 aatttaagtg ctggtatctc tgctccgatt ctctcactgt gtacatatga aactttatag
15481 aacaagaaag agtgctggcc aggcgcggtg actcatgcct gtaatcctag cactttggga
15541 ggccgaggtg ggcagatcac gaggtcagga gatcgagacc atcctggcta acacggtgaa
15601 accctgtccc tactaaaaat acaaaaaaaa aaaaaaaatt aaccaggcgt ggtggtgggc
15661 gcctgcagtc ccagctactc aggaggctga ggcaggagaa ctgcttgaac ccaggaggcg
15721 gaggttgcag tgagctgaga tcacgccatg gcactccagc ctgggcgaca gagcgagact
15781 ccgtctcaaa aaaaaaaaaa aagagtgcta caaaacagag agcacatctg cctttaagtc
15841 taacgagaat gttaggcagg gcacagtgac tcacgcctgt catcccagca ctttgggagg
15901 cagaggaaaa tggattgctt gaggagatca agaccagact gggcaacata gtgagccctg
15961 tctctacata aagaaaatac aaaaaattag ctgggatgtg gatgacctgc agtcccagct
16021 actcaagaga ctgaggtggg agcttgagct tgagcgtggg aggcagaaac tgcagtgagc
16081 tgagattgtg tccctgcact ctagcctgga caacagagca gaactctatc tcaaaaaata
16141 aataaataga attaagagaa tgttagtaca attcctaata aggcattgcc tagggatggc
16201 taaaatacat gatttccttg tcaaaacatg aagggataaa ccacagcagt gttttggccc
16261 aagaactatt tggtgcttat taaaaatgta ggttctgggc tgggcgtggt ggctcatgcc
16321 tgtaatccca gcactttggg agaccgaggt gagtggatca cctgaggtca gaaattcgag
16381 accatcatgg ccaacatagc aaaaccctgt ctccaataaa aatacaaaaa ttagccgggc
16441 atggtgaccc gggcctataa tctcagctac tcaggaagct gagacagaag aatcacttga
16501 acccgggagg cagaggttgc agtgagctga gatcgcacca ctgcactcca gcctgggtaa
16561 cagagcaagg ctccatctca aaaaataaaa taaaataaat aaaataaaaa ataaaaatgt
16621 aggttctgag gtcttctcct gatctaatga tgcaggattt agccaaaaga tcaagatggt
16681 aatttgcatt tttaataagc aaggtgattc ttaggcacac tggagtttga aaaccacccg
16741 atggtttcga aagtcccttc caagcctaat ttnnctttaa tcacaaaatg gcttcataga
16801 ggataaattt tttcaggaat ctttgagagg attaaatatc tttgagaggg ataaacagga
16861 tgaagcaagc cttaacaatg tcactctatt actaataaca acatttattc agtgttcatt
16921 tgtgccaagt atgtgccaaa ttcgcttata cacataatcc cacttattca tgtcaatgtc
16981 cttnagctaa agaccaccag ggacacacct gtctttaaac aagttgagct tattacttgt
17041 tgcagcaagg gaggacatgc tccttgggga agcatggact gtctcagtaa cagagcttag
17101 aaagaaattg ttataggatt tgcacttcag ttgtgcgatt tggggaagga gctaaaaaag
17161 ttggagttca ctccagatta gatgttagca gaaagcaggg ttcaattttg tgatttagtt
17221 atctcaagaa atcttanccg tagggagggg gagactagaa cacggataac ctgtaatcca
17281 taaagaagtg gcagttaatc attttggctg agagagtgag ggcttgggat tttgagagtg
17341 gagcattgac tttgtttttg tctgcgctta ggcaaagtta agaagtggat ttattttatc
17401 tcatttcatc ctggtctcgg agtagccttg tctgaagttg ttattctgtg agactgttta
17461 tgtctaatag cggagtaaca tgtcctcact gcggagtgcc aggccagcat ctgaatgtca
17521 gaggctactc ttttttctca cttttgttct cattaatcag actatagtcc atgagatact
17581 cctgctctga gtggttatat aatttgccat ggagctaatc agtggccttc tgagtacagg
17641 cggcctgagt ccaaagctca cactcttgcc cgtgaagctt tatggcctcc ctcacgcttg
17701 aaaaagggaa agcaatctat aaagtagtat acggtacttc tcagtcttgg gcccagtgac
17761 catagaaacc tttcccttgc ttgttatcgt aagttcacta ccagggactg atctctagtt
17821 agacgacgtg cccacgaaag gcatagttaa aagctgtctt aaagcattgg gttaacgaag
17881 tcaaaactag ccaagataag aatctagatt tgtgtccggc cctggactgg aaaattgtgt
17941 aaagacaaaa atgtaaggta gagcagtctc tgccatccag ggaaatgagt cagtgctttt
18001 ggcattctac ctcagcaacc tctctggaat cctggagcaa ttctataatg gcatagatct
18061 ttcccagaaa attcacgggg aataattcaa tcatatagac agagccacga atttcaggtc
18121 aaaagttcag actgactgca cagataaatt tagaaaacac taacaatcca aataaaagca
18181 acacagagca gtatgtacag gcagcgttag aatataccag agaacaagaa cacaatctac
18241 aatcatttcc agtgaatgca ggatgttaaa gagatgcata aaatcccctt accgctgagg
18301 gccccttttg tgttgttctt gccaacgcag cagccatcct gctatataga ctggctgtgc
18361 agccgcaggc cccatcacac tgaactcgca tcatccgtgt caaccagcca tggggaaggt
18421 gagcagaaca caaattaaat aaaatgaaaa aaaagttgcc tttatataat gcctgttagg
18481 agcaaataat gtaattcgga acgattcttc ctttgcagat caccttctat gaggacaggg
18541 ccttccaggg ccgcagctac gaaaccacca ctgactgccc caacctgcag ccgtatttca
18601 gccgctgcaa ctccatccgg gtggagagcg gctgctggat gctctatgag cgtcccaact
18661 accaaggtca acaatacttg ctgcggcgag gggagtaccc cgactaccag caatggatgg
18721 gcctcagcga ctccatccgc tcctgttgtc tcatccccca agtgagtttt ctagatttcc
18781 atcatgccgc cagagtcccc actgtattgt caatgtgggt tacagggagg gaggtttgca
18841 tttaaaaaca cctaagggtt agatggacat cagagacctg aataagccag atagataaca
18901 tgcacaaaaa cagcagagaa tgtaaggaag aacccactta gaggaagaat ccgtttttac
18961 ttgaaatttt tgcatccaat aagtcaatta aaagaggtct gtaacaaatg taatatcata
19021 atgggatata aaacaaaact tgcaaatggg aagctggttg ggcataaaaa gacggtattt
19081 ttaacaaatt attttgtcta tagtaaaaga atttctaatg aatgaattag atagattcca
19141 ccatggacta gtaaacctca aagctgtatt gttaatatag gctattcaaa ggttgtgtcc
19201 aactttggaa aaggtaattt ttcttaattt ggaaaatcag ttaaattctc attccaaatg
19261 actatttaac tttacactga agtacaagat tttttaaatc ttactttagt ggtaatttat
19321 atgtttgtaa tttgggagat aataaccctt actaaagaaa tactagtgaa ataaattatt
19381 tctatttttc cccccaaatg tagtttgaat taacacaggt aattaggatc agatatctca
19441 gttcttgatg gattctaact cagagtttga acctcttaaa aattccatct cctaaataag
19501 aatgaatttc aggtcaaata gaaaatgagc gtgccagtat ttaggtgcta gtggaagaca
19561 gatccatgcg cagcaaccac agtaatctac attttacact gtctaaattt tacaatgaca
19621 attccatgcc acaacctacc aagttcatct gttctttggt tggacaaatt ctggaagaga
19681 ctcatttgct tttttccatc cttctttctg tggaccgagt agacagtctc ccacaggctg
19741 cggctgtacg agagggaaga ccacaaaggc ctcatgatgg agctgagtga agactgcccc
19801 agcatccagg accgcttcca cctcagcgag atccgttccc tccacgtgct ggagggctgc
19861 tgggtcctct acgagctgcc caactaccgg gggcggcaat acctgctgag gccccaagag
19921 tacaggcggt gccaggactg gggggccatg gatgctaagg caggctcttt gcggagagtg
19981 gtggatttgt attaaaatag cttaacacta ccaatttccc attttggaac ctaataaata
20041 tttagtctgc attgctggca attgctgact tctgtcattc tttcattgtg caaatcagtt
20101 cacctttaaa tgctccttgt caaaagttaa gaagtgaatg gggtggggga cggggtctat
20161 tggagaagag cttcaaggta gagtgagttt gaacaagcct cagacgttgg ggtggaggca
20221 gggtgtagcc tgnccgagaa agaaaacgca gggcaatgcc agagacctgg gagaggctga
20281 ctggtgagag gggaggcaat tcaactangc accttgagga caatgattgg gaagtttcct
20341 tctaaccaaa atgggttagg acnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
20401 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
20461 ggccaccgca gccattgccg tacctttgaa caaagttaaa gactattcat cttcttttga
20521 aaatggctcc tgtccagaag tgtagctctt ggtcagtact acccctggcc caaatgctgt
20581 gtcaattata gaaactgcac atcagtttca tggtgaccag ctattgcaaa taaattaata
20641 ttaagagata cacatcaatc ttttaaatag attttcatgg tatagtgtaa cccaaacata
20701 aaaaataact acaaaaaaca tcgttctggc ataaggacgc atgtatgcat atgtttatca
20761 cagcactatt catgacagca aagacatgga atcaacctaa atgcccatca atggtaggct
20821 ggttttacaa atgtggtaca tatatacaat ggaatactat gcagccataa aaaagaatga
20881 gaccctgtcc tttgcagcaa catagatgga gctggaggcc attatcctaa gcaaactaac
20941 acaggaacag aaaacaaaat acctcatatt ctcgcttcta agtgggacct aaactttgag
21001 tacatgtgga caagaagaaa acaagagaca ctggggcctg cttgaggttg cagggtgggc
21061 ggttggagag gatcaaaaaa ctacctgtca ggtactatac ttatcacctg ggtgataaaa
21121 taatctgtac accaaacctt cacaacatgg caatttacct gtattacaaa cctggatacg
21181 tgcccctaaa tctaaaataa aagtttaaat aaacaaatac gtaagtcctg taattacaaa
21241 atgggctcaa atttaaaggt gctttaaaga agccataatt tctggagcct tttattaaac
21301 taaaatctgc ttgctcataa gcaaagccct aaaaagtaaa aataaaaaaa aaaaaaagaa
21361 agcaattacg agtcttttca tcagcagaga atttatttat tttaacttaa aaatctccct
21421 tcaaagtaaa aggcctccca taatcttact actgtacaaa ttctataaag aagttgaggg
21481 gagtccttct gacgcccctc attgctaact cttgtttata gttggtgggc acccttctgg
21541 gattttctcc ttgtttatat agctctctta taaacacatg cttcttttct ttacaaaaat
21601 ggaatcatgc tatacatatt agtctgcaac ttgcttttaa aatgtattat aatatggaca
21661 tatatctagg tcagtatctt attctgtttg atggttgaat tgcatcccat tgtttggagg
21721 tcccttagac catttcacca tttgtccact taagtgactg ggcttttcca atgttgcttt
21781 taccaacaat gctgcaaaga ataacattgt acatatacgc taatcctgac atgccataat
21841 tttaaaaaga tagcgaccta gaagtgagac taccggctca tagtgcaagt ttattttatt
21901 ttatttattt attttttgag acatggtcac actctgttgt ccaggatgga tgcagtggca
21961 caaacccagc tcactgcagc ctcgacctca caggctcaag cgatcctccc atctcagcct
22021 cctaagtagc tggggctaca ggcgcgcacc accatgcctg actaattttt tcactttttt
22081 gtagagaagg ggctcactat gttgccaggg ctggtctcga actcctgggc tcaagtgacc
22141 ctcccacctt ggcctccgaa agtgctggga ttacaggtgt gagccaccac acccagccac
22201 aagtttattt tccatttcaa tagcctccaa ttattagcca ctagagactc ttaacttcct
22261 tgagttagga tccttaccaa tttttgagca cctaccatac gcctgctata tgtagcaatg
22321 gggatgaaga aaacaatcaa aacaaaacaa aagaaaaagg tatttcccta ccaccgtaga
22381 gctctatata gaaagaatac aaaaaaaaaa aagcagccag aaaataagaa ttaaaataat
22441 ttgtattgca catagttggt gtttaattca taaataccac ttacaaagat ttatgactca
22501 aagacaagac aaagtacttc catgggttga cacagggctg taagcaattc tttaaacatg
22561 aaagaagctg gacacatagg tcatattcca ctccagtact cttcccagtc catcaaactg
22621 ctctcttcca ggccaataag tactttctga agtcttcctc gagtccaact tctagannnn
22681 nnnnnagctc ccctttgtgt tcatgcatta atttcgtctg agtcaaaggc cttgtgtact
22741 ctcgctcgtt caggggtaaa ggtgtattct agatc
//