GenBank-Updates@genbank.bio.net (08/18/90)
LOCUS HUMIGHHSG3 893 bp ds-DNA PRI 18-AUG-1990
DEFINITION Human mutant germline Ig H-chain DNA with a deletion of IgG1, IgG2,
IgG4 and IgA1, clone pBR0.9EZZ.
ACCESSION M25382 J03079 M29704
KEYWORDS alpha-immunoglobulin; constant region; gamma-immunoglobulin;
immunoglobulin heavy chain; minisatellite repeat; switch region.
SOURCE Human (TOU and HASS families) cell line EZZ DNA, clone pBR0.9EZZ.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 893)
AUTHORS Keyeux,G., Lefranc,G. and Lefranc,M.-P.
TITLE A multigene deletion in the human IGH constant region locus
involves highly homologous hot spots of recombination
JOURNAL Genomics 5, 431-441 (1989)
STANDARD full staff_entry
COMMENT Draft entry and computer-readable sequence for [1] kindly provided
by M.-P.Lefranc, 08-JUN-1989.
FEATURES from to/span description
site 64 71 chi sequence
site 146 155 core of hypervariable minisatellite
site 165 174 core of hypervariable minisatellite
site 215 219 switch sequence repeat tetranucleotide
rpt 847 854 direct repeat copy A
rpt 857 864 direct repeat copy B
BASE COUNT 215 a 213 c 216 g 249 t
ORIGIN 1 bp upstream of BamHI site; chromosome 14q32.
1 ggatccacca ttctggggtc tggaggacag tggccccctt cccacagctc cgctaggcag
61 tgccctggtg gggacattat atgggggttc aaccacattc tctttggcac tgctctagta
121 gaggttctct gtgagggctc catgctggca ggaggcttct gtctgggcag ctaggctttc
181 tcatacattt ctgaaatcta gagggaagat gccaagcttc cttcactctt gcattctggg
241 ggcctacagg cttaacacca gagtggaagt caccaaggct tatagtggct tgcactctcc
301 aaagcagcag cctaagctgt acttggggcc ctttgagcca aggctggagc cagaggaacc
361 aggatgtgga gagcagtgtc ccaaggctgc acaggcagag tggccatggc atggccacaa
421 aacatctttc ctcttggcct ctgggctgtg atgggaaaga ccacctcaga gatttccaaa
481 atgccttcaa ggcctttttc cctttgttct ggatatgagc acttagctcc cttttagtta
541 tgctaatctc tctagcaact ggctgctcca tagcctactt atatttgtct cctgaaaata
601 ccttttcttt tctaccacat ggccaggctg tgaattttcc acatttttta tgctctgctt
661 ccctttgttg atgaaaaaag ccaaactcca taaaacactt gaaaaattga ttctgagcca
721 aatatgagag ccatgaactg tggcacagcc tcaaaaggtc ctgagaacac ctgtgcaagg
781 tggttgggtt gcggcctgct tttatgtttt agggagacat atcaatcaat acatgtaaag
841 tatacattgg tttgatttgg tttggaaaag caggacaatt caaatgggaa ttc
//GenBank-Updates@genbank.bio.net (08/21/90)
LOCUS HUMIGHHSG3 893 bp ds-DNA PRI 21-AUG-1990
DEFINITION Human mutant germline Ig H-chain DNA with a deletion of IgG1, IgG2,
IgG4 and IgA1, clone pBR0.9EZZ.
ACCESSION M25382 J03079 M29704
KEYWORDS alpha-immunoglobulin; constant region; gamma-immunoglobulin;
immunoglobulin heavy chain; minisatellite repeat; switch region.
SOURCE Human (TOU and HASS families) cell line EZZ DNA, clone pBR0.9EZZ.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 893)
AUTHORS Keyeux,G., Lefranc,G. and Lefranc,M.-P.
TITLE A multigene deletion in the human IGH constant region locus
involves highly homologous hot spots of recombination
JOURNAL Genomics 5, 431-441 (1989)
STANDARD full staff_entry
COMMENT Draft entry and computer-readable sequence for [1] kindly provided
by M.-P.Lefranc, 08-JUN-1989.
FEATURES from to/span description
site 64 71 chi sequence
site 146 155 core of hypervariable minisatellite
site 165 174 core of hypervariable minisatellite
site 215 219 switch sequence repeat tetranucleotide
rpt 847 854 direct repeat copy A
rpt 857 864 direct repeat copy B
BASE COUNT 215 a 213 c 216 g 249 t
ORIGIN 1 bp upstream of BamHI site; chromosome 14q32.
1 ggatccacca ttctggggtc tggaggacag tggccccctt cccacagctc cgctaggcag
61 tgccctggtg gggacattat atgggggttc aaccacattc tctttggcac tgctctagta
121 gaggttctct gtgagggctc catgctggca ggaggcttct gtctgggcag ctaggctttc
181 tcatacattt ctgaaatcta gagggaagat gccaagcttc cttcactctt gcattctggg
241 ggcctacagg cttaacacca gagtggaagt caccaaggct tatagtggct tgcactctcc
301 aaagcagcag cctaagctgt acttggggcc ctttgagcca aggctggagc cagaggaacc
361 aggatgtgga gagcagtgtc ccaaggctgc acaggcagag tggccatggc atggccacaa
421 aacatctttc ctcttggcct ctgggctgtg atgggaaaga ccacctcaga gatttccaaa
481 atgccttcaa ggcctttttc cctttgttct ggatatgagc acttagctcc cttttagtta
541 tgctaatctc tctagcaact ggctgctcca tagcctactt atatttgtct cctgaaaata
601 ccttttcttt tctaccacat ggccaggctg tgaattttcc acatttttta tgctctgctt
661 ccctttgttg atgaaaaaag ccaaactcca taaaacactt gaaaaattga ttctgagcca
721 aatatgagag ccatgaactg tggcacagcc tcaaaaggtc ctgagaacac ctgtgcaagg
781 tggttgggtt gcggcctgct tttatgtttt agggagacat atcaatcaat acatgtaaag
841 tatacattgg tttgatttgg tttggaaaag caggacaatt caaatgggaa ttc
//