GenBank-Updates@genbank.bio.net (08/22/90)
LOCUS BOVMHWIA 1761 bp ds-DNA MAM 22-AUG-1990
DEFINITION Bovine MHC class II BoLA-DQA-alpha gene, exons 2-4.
ACCESSION M30117
KEYWORDS cell surface glycoprotein; class II gene;
integral membrane protein; major histocompatibility complex;
pseudogene.
SOURCE Bovine (Holstein, isolate 2042) DNA, clone WI.
ORGANISM Bos taurus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Artiodactyla; Ruminantia; Pecora; Bovidae.
REFERENCE 1 (bases 1 to 1761)
AUTHORS van der Poel,J.J., Groenen,M.A.M., Dijkhof,R.J.M., Ruyter,D. and
Giphart,M.J.
TITLE The nucleotide sequence of the bovine MHC class II alpha genes:
DRA, DQZ and DYA
JOURNAL Immunogenetics 31, 29-36 (1990)
STANDARD full staff_entry
COMMENT Draft entry and computer-readable sequence for [1] kindly submitted
by J.J.van der Poel, 21-NOV-1989.
FEATURES from to/span description
pept / 356 604 MHC BoLA-DQA-alpha chain, exon 2 (AA at 358)
1053 1334 MHC BoLA-DQA-alpha chain, exon 3
1573 1727 MHC BoLA-DQA-alpha chain, exon 4
pre-msg < 1 > 1761 MHC BoLA-DQA-alpha chain mRNA and introns
IVS < 1 355 MHC BoLA-DQA-alpha chain intron A
IVS 605 1052 MHC BoLA-DQA-alpha chain intron B
IVS 1335 1572 MHC BoLA-DQA-alpha chain intron C
IVS 1747 > 1761 MHC BoLA-DQA-alpha chain intron D
BASE COUNT 451 a 469 c 367 g 474 t
ORIGIN Chromosome 23.
1 ccagctaagg ctaaaactgt aaaagtgaat tagttccgac tgacacagtg gagggatgtt
61 cttcagcaac agttggtaac ccaggacaag taccagagga aaagatatta catatatcct
121 gtctggaaaa ggagtcaaga tgtgttcgaa agataaggag gctttgttcg aaggcttttt
181 aactaaccag acaactacca acacagagcc aagaaggagc aggtactggg aattttgtct
241 agaaactggg tcacaaatga agcccacaat gtttgatagt caatttcttc tttcactttg
301 cttaataagg gtcttttctc tatttttccc tttcttgctc ctcactccga ctcagctgac
361 cacattggca cctatggcat aagcatctac cacacatatg gtccctctgg ctactatacc
421 catgaatttg atggagatga agagttctac gtggacctgg aaaagaggga gactgtctgg
481 cgtctgcctg tgtttagtaa atttgcaact tttgaccctc agggtgcgct gagaaacata
541 gctacgtcga agcacgattt ggaggtcttg attcaaaggt ccaactctac tgctgctacc
601 aacagtatgt gtccccactc tgcctctctt tattaatcta ccccttcaaa ccaggcctca
661 ctcccttttc cctagggata gatacccttc accactctat aaaactctct cccttccaag
721 gacaccacat tttctcatgc taatagctga accctcatcc tctgccttct tccaactcac
781 gtatttccat atgattgaaa gatccctact cccataatgc aatctttgaa tattccatgg
841 agaggtccca cagacctccc acttgacagg tcgtcaaaaa cagggggaca aggataaagc
901 agaagcaaca tatagtgcct cccaacagaa gggaaacaag agctcctcct ctgtcagagt
961 gcaactgttg gtgggagggc tcccccaaga ggcagtgcag aatcagggca gaactactcc
1021 catttcacat ctgtgctgtt tcctcaccat agaggttcct gaggtgactg tgttttccaa
1081 gtctcccgtg atgctgggtc agcccaacac tctcatctgt catgtggaca acatctttcc
1141 ccctgtgatc aacatcacat ggttgaggaa tgggcactcg gtcacagagg gagtttctga
1201 gaccagtttt ctcatcaaga gtgattattc ttttctcaag atcaattatc tcaccttcct
1261 cccttctgat gatgacgttt atgactgcaa agtggagcac tggggtctgg atgagccact
1321 tctgaaacac tggggtatgt acgagttcca ccccttttgg gtaccttctt ttctctgtca
1381 ggtccacaac atcatgtttg ttatccccta atcctcgtgg ccttagactt cgagggattc
1441 taatgataga cctcactctc ttctctcagc tccatgcccc aaatctgtag aaccaacccc
1501 tcttcacccc attccacata cacacacaga aacactctgt attgtgactt ccacaaaact
1561 tcacttttgc agagcctgat attccagccc ctatgtcaga gctgacagag actgtggtct
1621 gtgccctggg gttgaccgtg ggcctcgtgg gcatcatggt gggcaccatc ctcatcatcc
1681 aaggtctgcg ctcaggtggc ccctccagac accaggggcc gttgtgagtc acactccaga
1741 aggaaggtag gaattcactg g
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