GenBank-Updates@genbank.bio.net (08/22/90)
LOCUS HPBHBVAA 3182 bp ds-DNA VRL 22-AUG-1990
DEFINITION Hepatitis B virus variant HBV-alpha1, complete genome.
ACCESSION M32138
KEYWORDS .
SOURCE Hepatitis B virus (isolate HBV-21) human blood cell viral DNA.
ORGANISM Hepatitis B virus
Viridae; ds-DNA enveloped viruses; Hepadnaviridae.
REFERENCE 1 (bases 1 to 3182)
AUTHORS Tong,S., Li,J., Vitvitski,L. and Trepo,C.
TITLE Active hepatitis B virus replication in the presence of anti-HBe is
associated with viral variants containing an inactive pre-C region
JOURNAL Virology 176, 596-603 (1990)
STANDARD full staff_entry
COMMENT Draft entry and computer-readable sequence for [1] kindly submitted
by S.Tong, 26-MAR-1990.
FEATURES from to/span description
pept 1376 1840 X protein
pept 1816 1896 pre-C/C protein
1900 2454 pre-C/C protein
pept 2850 837 pre-S/S protein
pept 2309 1625 P protein
site 1897 1899 pre-C/C protein in-frame stop codon
BASE COUNT 730 a 865 c 683 g 904 t
ORIGIN
1 aactccacaa ccttccacca aactctgcaa gatcccagag tgagaggcct gtatctccct
61 gctggtggct ccagttcagg aacagtaaac cctgttccga ctactgtctc tcccatatcg
121 tcaatcttct cgaggattgg ggaccctgcg ctgaacatgg agaacatcac atcaggattc
181 ctaggacccc tgctcgtgtt acaggcgggg tttttcttgt tgacaaaaat cctcacaata
241 ccgaagagtc tagactcgtg gtggacttct ctcaattttc tagggggaac caccgtgtgt
301 cttggccaaa attcgcagtc cccaacctcc aatcactcac caacctcctg tcctccaact
361 tgtcctggtt atcgctggat gtgtctgcgg cgttttatca tcttcctctt catcctgctg
421 ctatgcctca tcttcttgtt ggttcttctg gactatcaag gtatgttgcc cgtttgtcct
481 ctgattccag gatcttcaac caccagcacg ggaccatgca gaacctgcac gactcctgct
541 caaggaacct ctatgtatcc ctcctgttgc tgtaccaaac cttcggacgg aaattgcacc
601 tgtattccca tcccatcatc ctgggctttc ggaaaattcc tatgggagtg ggcctcagcc
661 cgtttctcct ggctcagttt actagtgcca tttgttcagt ggttcgtagg gctttccccc
721 actgtttggc ttttagttat atggatgatg tggtattggg ggccaaaact gttcaccatc
781 ttgagtccct ttttaccgct gttaccaatt ttcttttgtc tttgggtata catctaaacc
841 ctaacaaaac aaaaagatgg ggttactctt tacattttat gggctatgtc attggatgtt
901 atgggtcttt gccacaagat cacatcatac agaaaatcaa agaatgtttt agaaaacttc
961 ctgttaacag gcctattgat tggaaagtct gtcaacgtat tgtgggtctt ttgggatttg
1021 ctgctccttt tacacaatgt ggttatcctg ctttaatgcc cttgtatgca tgtattcaat
1081 ctaagcaggc tttcactttc tcgccaactt acaaggcctt tctgtgtaaa caatacctga
1141 acctttaccc cgttgcccgg caacgcccag gtctgtgcca agtgtttgct gacgcaaccc
1201 ccactggctg gggcttggtc atgggccatc agcgcatgcg tggaaccttt caggctcctc
1261 tgccgatcca tactgcggaa ctcctagccg cttgttttgc tcgcagccgg tctggagcaa
1321 acattctcgg gacggataac tctgttgttc tctcccgcaa atatacgtcg tttccatggc
1381 tgctaggctg tgctgccaac tggatcctgc gcgggacgtc ctttgtttac gtcccgtcgg
1441 cgctgaatcc cgcggacgac ccttctcggg gccgcttggg actctctcgt ccccttctcc
1501 gtctgccgtt tcgaccgacc acggggcgca cctctcttta cgcggactcc ccgtctgtgc
1561 cttctcatct gccggaccgt gtgcacttcg cttcacctct gcacgtcgca tggagaccac
1621 cgtgaacgcc caccaattct tgcccaaggt cttacataag aggactcttg gactctctgt
1681 aatgtcaacg accgaccttg aggcatactt caaagactgt ttgtttaagg actgggagga
1741 gtcgggggag gagattagat taatgatctt tgtactagga ggctgtaggc ataaattggt
1801 ctgcgcacca gcaccatgca actttttcac ctctgcctaa tcatctcttg ttcatgtcct
1861 actgttcaag cctccaagct gtgccttggg tggctttagg acatggacat tgatccttat
1921 aaagaatttg gagctactgt ggagttactc tcgtttctgc cttctgactt ctttccttca
1981 gtacgagatc ttctagatac cgcctcagct ctatatcggg aagccttaga atctcctgag
2041 cattgttcac ctcaccatac tgcactcagg caagcaattc tctgctgggg ggatctaata
2101 actctatcca cctgggtggg tggtaatttg gaagatccaa catctaggga cctagtagtc
2161 agttatgtta acactaatat gggcctaaag ttcaggcaac tattgtggtt tcacatttct
2221 tgtctcactt ttggaagaga aacggtcata gagtatttgg tgtcttttgg agtgtggatt
2281 cgcactcctc cagcttatag accaccaaat gcccctatct tatcaacact tccggagact
2341 actgttgtta gacgacgagg caggtcccct agaagaagaa ctccctcgcc tcgcagacga
2401 aggtctcaat cgccacgtcg cagaagaact caatctcggg aatctcaatg ttagtattcc
2461 ctggactcat aaggtgggaa actttacggg gctttattct tctactgttc ctgtctttaa
2521 ccctcattgg aaaacaccct cttttcctaa tatacattta caccaagaca ttatcaaaaa
2581 atgtgaacaa tttgtaggcc cactcacagt caatgagaaa agaagactgc aattgattat
2641 gcctgctagg ttttatccaa aggttaccaa atatttgcca ttggataagg gtattaaacc
2701 ttattatcca gaacatctag ttaatcatta cttccaaacc agacattatt tacacactct
2761 atggaaggcg ggtgtattat ataagagaga aactacacat agcgcctcat tttgtgggtc
2821 accatattcc tgggaacaag agctacagca tggggcagaa tctttccacc agcaatcctc
2881 tgggattctt tcccgaccac cagttggatc cagccttcag agcaaacact gcaaatccag
2941 attgggactt caatcccaac aaggactcct ggccagacgc caacaaggta ggagctggag
3001 cattcgggct gggattcacc ccaccgcacg gaggcctttt ggggtggagc cctcaggctc
3061 agggcatact acaaaccttg ccagcaaatc cgcctcctgc ctccaccaat cgccagtcag
3121 gaaggcaacc tacccctctg tctccacctt tgagaaacac tcatcctcag gccatgcagt
3181 gg
//