GenBank-Updates@genbank.bio.net (08/24/90)
LOCUS MUSNGFX 2170 bp ds-DNA ROD 24-AUG-1990
DEFINITION Mouse nerve growth factor gene, 5' flank.
ACCESSION M33683
KEYWORDS nerve growth factor.
SOURCE Mouse (strain BALB/c) DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (sites)
AUTHORS Hengerer,B., Lindholm,D., Heumann,R., Ruether,U., Wagner,E.F. and
Thoenen,H.
TITLE Lesion-induced increase in nerve growth factor mRNA is mediated by
c-fos
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 3899-3903 (1990)
STANDARD full staff_entry
REFERENCE 2 (bases 1 to 2170)
AUTHORS Hengerer,B., Lindholm,D., Heumann,R., Ruether,U., Wagner,E. and
Toene,H.
JOURNAL Unpublished (1990)
STANDARD full staff_entry
COMMENT Draft entry and computer-readable sequence for [1] kindly submitted
by B.Hengerer, 26-MAR-1990.
FEATURES from to/span description
pre-msg 1882 > 2170 nerve growth factor mRNA and intron
IVS 1915 > 2170 nerve growth factor intron A
site 1882 1914 non-expressed exon 1
signal 1327 1332 CAAT box
signal 1493 1498 CAAT box
signal 1833 1838 TATA box
binding 1916 1922 AP-1 binding site
BASE COUNT 536 a 528 c 555 g 551 t
ORIGIN
1 tggcttagat cttactcact ttgcttttta aaatttcttc ttttccaaaa aacacaagtg
61 attgaaatcc ttctgtcctt caaggtgaca ccacaaggac acaaacaaaa gctcagcttg
121 tgtcatttgt agttccaccc ctgaatgcac aggtagttat tatttgagct tgtgctttaa
181 aaaaaataca gtgttatatg tgaaatgatt aatggagaaa tgtatcctat tatctggtaa
241 ttgttagttt ttcattaaca gtgataagtt tcctcacaga gcatcatggc catgatgtca
301 gctctgtttt ctgctatctg gtgttgcctg gtctctcacc tttactccta atgtgtgttc
361 atccaccagc ctggacctca cagagcatta acaaggaaaa aaaaagttca ctctcttctt
421 ccttcatcct cccagagtac ctgaaatggc atgatggtag gtgtgggaac aaagtcaaag
481 tcaaagggaa gttgaaattc agaggactgg aaatacatca ataggtcctc tccttcccac
541 gtgaccttca atggggaaaa aggaccacct gggcctcact ccatcccaac ttcatggagc
601 atgattcttg cctagactaa ggtgtcacct tcgtacctta ccttccctct gtcactcact
661 ttcctgcatc cattccttcc tgtggcattc atgaaggtgg gggtggggca tagaacatgt
721 ctttccgaag gaagtaagtc atctctaaca agtgtgtgtg tgtgtgtgtt catttccaaa
781 atccatagaa ttttattaca attgttagtg cacatttggt gaaaaagctg acttagggca
841 tatttctccc ttgaagctga gtgtaaacac catagaggaa ggggaggtca aacggggaag
901 accccatcag ctcctgaatc tatcagatcc aagacattct ggagggccaa ctgaggaccc
961 cccaccataa gtaagtagac aaaagaggtg agagagaatt gaggtgagcc ctggggtggt
1021 gcagaaggcc tggctttctc ctgggtctgt gtttactgac tcctaaaaac cgacagaagc
1081 cctaggaccc cagatctaga aacacgcagg gagcacatac agacacagtt ccatctacag
1141 tttccaaggg accagctctc ctgggaggcc cctgcaatgc cagtgctaag gctggcagtg
1201 ggagtgggag ttggggtaat ctgaacacct aaggtcctct tcctttgacc tcaggcagat
1261 atacctctgt cttgacattc tagttaattc tgcttctgcc tggtttcaga gcaacccctg
1321 gcactggcca atccaggagt ttccggtgtt gtgggtgttc tcagtgttcc ttcagctctc
1381 agatttgcag agatagcaac acctgatatc ctggccacca aagaagacta agtcacccca
1441 ggaggctagc aaggcagtga gccaggggaa gaggtaaagg gactccaact cagccaatca
1501 actcagccct gctcagcctg tctgcccatt ggtgtttgga gccagctacc ttgcctggtg
1561 ccctagaaaa tctctctctg catctgtgac ctccccccac catgcatttt catctaaacc
1621 aggggttttg aattcttccc tgactggctt ttcctggcta tgtcccatca actcgggagc
1681 tatccatccc ttgtccccag gacccttaca acccggaccc ctgggtctag tcacagcagg
1741 tgcgtgctgg gattggagtt ggccagagag ggaggggtcg ggtgagtggg gggcaggatt
1801 tggagagggt gtgacgagcc tggaggaggg gctaaataca gtcaggaagc ctgttaaaga
1861 agctctgtgc tccagcacgg cagagagcgc ctggagccgg aggggagcgc atcggtgagt
1921 caggcttctc tgagccgagc ccgatacggg tgcaacgcgg tgcggcggac tggggttgcc
1981 gggctccctg ggacggtgtg cttggatccc tgtctagcta gatctttgtg ggctgaagcg
2041 cacccttgaa agaactgtcc cgagtagatg taggaacacg agatcgtggg cacgcaaggg
2101 aagcgaaggg agtgagggtc tccctggtcg tgaaattccc tgttcctgga tgaccagaag
2161 taccaaagtc
//