GenBank-Updates@genbank.bio.net (08/28/90)
LOCUS HUMIGHWD 596 bp ss-DNA PRI 28-AUG-1990
DEFINITION Human Ig germline heavy-chain gene V region.
ACCESSION M36530
KEYWORDS germline; immunoglobulin heavy-chain; joining exon.
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 596)
AUTHORS Buluwela,L., Albertson,D.G., Sherrington,P., Rabbitts,P.H.,
Spurr,N. and Rabbitts,T.H.
TITLE The use of chromosomal translocations to study human immunoglobulin
gene organization: Mapping D-H segments within 35 kb of the C-mu
gene and identification of a new D-H locus
JOURNAL EMBO J. 7, 2003-2010 (1988)
STANDARD simple staff_entry
FEATURES from to/span description
pept 87 132 Ig heavy chain V region precursor, exon 1
236 / 546 Ig heavy chain V region precursor, exon 2
sigp 87 132 Ig heavy chain V region signal peptide
236 246 Ig heavy chain V region signal peptide
matp 247 / 546 Ig heavy chain V region
BASE COUNT 150 a 122 c 183 g 141 t
ORIGIN
1 ctgcagctct gggagaggag ccccagccat gagattccca ggtgtttcca ttcagagaga
61 tcagcactga acacagaggg ctcaccatgg agtttgggct gagctgggtt ttccttgttg
121 ctattttaaa aggtgattca tggagaaata gagagattga gtgtgagggg acatgagtga
181 gagaaacagt ggatttctgt ggcagtttct gaccagggtg tctctgtgtt tgcaggtgtc
241 cagtgtgagg tgcagctgtt ggagtctggg ggaggcttgg tccagcctgg gggttctctg
301 agactctcat gtgctgcctc tggattcacc ttcagtgacc actacatgag ctgggtccgc
361 caggctcaag ggaaagggct agagttggta ggtttaataa gaaacaaagc taacagttac
421 acgacagaat atgctgcgtc tgtgaaaggc agacttacca tctcaagaga ggattcaaag
481 aacacgctgt atctgcaaat gagcagcctg aaaaccgagg acttggccgt gtattactgt
541 gctagagaca cagtgagggg aggtcagcgt gagcccagac acaaacctcc ctgcag
//