GenBank-Updates@genbank.bio.net (08/30/90)
LOCUS DOGFIXA 3080 bp ss-mRNA MAM 30-AUG-1990
DEFINITION Canine blood clotting factor IX mRNA, complete cds.
ACCESSION M33826
KEYWORDS blood clotting cascade protein; blood clotting factor IX; protease.
SOURCE Dog liver, cDNA to mRNA, clone dF9.28.
ORGANISM Canis familiaris
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Carnivora; Caniformia; Canoidea; Canidae.
REFERENCE 1 (bases 1 to 3080)
AUTHORS Axelrod,J.H., Read,M.S., Brinkhous,K.M. and Verma,I.M.
TITLE Phenotypic correction of factor IX deficiency in skin fibroblasts
of hemophilic dogs
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 87, 5173-5177 (1990)
STANDARD full staff_entry
COMMENT Draft entry and computer-readable sequence for [1] kindly submitted
by J.H.Axelrod, 23-APR-1990, for release after publication.
FEATURES from to/span description
pept 22 1380 factor IX protein precursor
sigp 22 138 factor IX signal peptide
matp 139 1377 factor IX blood circulatory protein
matp 577 1377 factor IX activated protein
matp 673 1377 factor IX activated protein
mRNA < 1 3080 factor IX mRNA
BASE COUNT 878 a 640 c 677 g 885 t
ORIGIN Chromosome X.
1 aagcagcgcc tgaataggat catggcagaa gcatcgggcc tcgtcaccgt ctgcctttta
61 ggatatctac tcagtgccga atgtgcagtt tttcttgatc gtgaaaatgc caccaaaatt
121 ctgagtcggc caaagaggta taattcaggt aaactggaag agtttgttcg agggaacctt
181 gagagagaat gtatagaaga aaagtgcagt tttgaagaag cacgggaagt ttttgaaaac
241 actgaaaaaa ccactgaatt ttggaagcaa tatgttgatg gagatcaatg tgaatccaat
301 ccatgtttaa atgacggtgt atgcaaggat gacattaatt cctatgaatg ttggtgtcga
361 gctggatttg aaggaaagaa ctgtgaatta gatgtaacat gcaacattaa gaatggcaga
421 tgcaagcagt tttgtaaatt gggccccgat aacaaggtgg tttgttcctg tactacggga
481 taccaacttg cggaagacca aaggtcctgt gaaccagcag tgccatttcc atgtggaaga
541 gtttctgtcc ctcacatttc tatgacacgc acccgtgctg aaactctttt ttccaatatg
601 gactatgaaa attcaactga agtggaaaaa attttggata acgtcaccca accgcttaac
661 gacttcactc gagttgttgg tggaaaagat gccaaaccag gtcaattccc ttggcaggtc
721 cttttgaatg ggaaagttga tgcattctgc ggaggttcca tcatcaatga aaaatgggtg
781 gtaactgcag cccactgtat tgagcctgat gttaaaatta ccatagttgc aggtgagcat
841 aacaccgaga agagggaaca tacagagcag aagcgaaacg tgattcgcac tattcttcac
901 cacagctata atgcaactat taataagtac aaccatgaca tcgcccttct ggaactggat
961 gagcccttaa cgctgaacag ctatgtaaca cctatttgca ttgctgacag ggaatactcg
1021 aacatcttcc tcaaatttgg gtctggctat gtgagtggct gggggagagt cttcaacaaa
1081 gggcgatcgg cttcaattct tcaatacctt aaagttccac ttgttgaccg agccacgtgc
1141 cttcggtcca cgaagttcac catttataac aacatgttct gtgctggctt ccatgaggga
1201 ggtaaagatt catgccaggg cgatagtggg ggaccccatg tcaccgaagt agaaggcata
1261 agtttcttaa ctgggattat tagctggggt gaagagtgtg cgatgaaagg gaagtatgga
1321 atatatacca aggtgtcccg gtatgtcaac tggattaaag aaaagacgaa gctcacctaa
1381 agaataatgt atttccaagg ttgacacgtt tagggtagaa aatggacaag gtcctttact
1441 aactaatcac tttttttatc tctttagatt tgcactatat acattctctg catactgctt
1501 tttctctttc tggggagaaa tctatctaga attcctattt tactagacta agtgaattag
1561 aaaatgtaat cactacggga atgtactgtg atgggacttg tgaccactcc cacaggtcta
1621 gcccttggca ccattgtgag gttaggttat tcctccgtcc cgtcagtgtt aagtttctcc
1681 actggggcaa ctccctgatt ctccctcctt ggcagcattc catgttccag acctttctta
1741 cctttcccat ggaaagcatc atcaaaatgt gttagatcta catccaggat atttgatcta
1801 gttcagaaca agtctaacac ctcacttgtt aaggaagaac acaggagcaa ctgacaggtt
1861 gcaactcacc agaaaacact atttcctttt ctgtatgctt attcctgctt ccttatctct
1921 tctgtttcct aatcctgaaa tcagtgtctc tctttctctt tctctctctc tttttcctac
1981 agaggtttaa aggagggaag ggacacatca tgctgtttta ctactgtcca cagttataca
2041 tgtctatcaa acccagactt gctttcagtt tggtctttga cttgcttttc ggagcatagg
2101 gatgaagcca ggtgcctgaa gaccttcagg aaaatttgtc tgaaagagtc atgttactga
2161 aatacatggc atcgtggaag gaatgaccga cccatcagaa tacgtccaat aagcatttgt
2221 aattgtgttg tgatagaggt aactaagaag agtgacatca actcctgcgt ctcatccccc
2281 atgtgaaaaa actgtgaact aaaagagaac agccagtgtg caacgtagaa ctagtagagt
2341 cttaaggaag aattcattgg tgggtctcca gtactggccg gagctaagga agaagttgcc
2401 ctcgaccaaa gaacatgagc accctgtctc ttaaactagc atgtccccac agtggagaag
2461 gatgtactgg tggcttaaag gcatgagtca ggggtgtctg ggtggctcag tggttgagcc
2521 tttggctcag ggcatgatcc cagcgtcctg ggattgagtc ccgcatcagg cttcctgcag
2581 ggggcctgct tctccctctg cttatgtctc tgcttctctg tgtgtgtgtg tgtgtctctc
2641 atgaaaaaaa taaataaaat ctttaaaaaa aaaaaaggta tgagtcattc cagtgagcca
2701 tctcactccc ccttttctgg tttcaggttc tctaggcaac cttttgatta taattaggcc
2761 ttccatattg aattttctaa agagttgctg accaacctct gcatgtactt tagtgtgtta
2821 ggctggctcc ctttatgaat taataaactg ttgttctggt tgatactgta gctttttgtg
2881 aatgtggctg atgtgaatca gtcatcccac atgttgttat atatgagact actgacaaaa
2941 tcatgtttgg gaccactttg acctgaccaa gctgctgcct tcacctcacc cccagccagg
3001 catttacttt agtccttcaa atattaagta ccaataaatg tcttttcaaa tttcaaaaaa
3061 aaaaaaaaaa aaaaaaaaaa
//