GenBank-Updates@genbank.bio.net (09/05/90)
LOCUS HUMIGKBC 1123 bp ds-DNA PRI 05-SEP-1990
DEFINITION Human rearranged Ig-kappa chain (subgroup II) gene VJ1-region.
variable kappa-gene of cell line RPMI 6410 together with the 5'
flanking region and J region.
ACCESSION M36859
KEYWORDS V-region; immunoglobulin light chain; kappa-immunoglobulin.
SOURCE Human cell line RPMI 6410 DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1123)
AUTHORS Weir,L. and Leder,P.
TITLE Structure and expression of a human subgroup II immunoglobulin
kappa-gene
JOURNAL Nucleic Acids Res. 14, 3957-3971 (1986)
STANDARD simple staff_entry
FEATURES from to/span description
pept 295 343 Ig-kappa chain VJ1-region precursor, exon 1
/hgml_locus_uid="LF0081F" /nomgen="IGKV"
/map="2p12"
774 > 1123 Ig-kappa-chain VJ1-region precursor, exon 2
sigp 295 343 Ig-kappa chain signal peptide
774 784 Ig-kappa chain signal peptide
matp 785 > 1123 Ig-kappa chain
recomb 1084 1085 V-region end/J1-region start
BASE COUNT 299 a 263 c 264 g 297 t
ORIGIN
1 acatgaacat gaacagaact tgaaggaaga cgaaggaaat aacttaattt ctccaacata
61 gacagcatag atttatgcct attcgttccc tccaaacaga gaagatatta agttcatttt
121 gctcacaaga gaggctccta ccctcccctt ggctctttcc accccactgc acccacccac
181 tagctgattt gcatattatc ccttagtgaa aatctttcct tgtgagtctg agataaaagc
241 tcagctctac ccttgccttg actgatcaga gtttcctcag ttcaccttct cacaatgagg
301 ctccctgctc agctcctggg gctgctaagg ctctgggtcc caggtaaggg tagaagggag
361 atgagggagg agaatggcat ggaacggtga gttctggggc cccatgcctc taacaacagt
421 gatctctggg ggtctcacta cactcctatg tgtgttcctt tcctgtattg gacatgcaca
481 tgttgtcctc cagagtgggg catgtgatga tcagatctgt gagagtgagg aagattcaag
541 cagaaacaag gatctgtgct ctggggaaga ctgacacaga aaggggatgg tgtggggtct
601 tctggagacc cctttgagcc ttggatccct tgagttccat tttgaaactg tgtatttttg
661 aaatatgaac aaatacatat atagcctgaa ataaacaaca aatcaaaatt taatgaatga
721 aaattacaca taaactttat acataacctt gctcttcttt ctatttattt caggatccag
781 tggggatgtt gtgatgactc agtctccact ctccctgccc gtcacccttg gacagccggc
841 ctccatctcc tgcaggtcta gtcaaagcct cgtatacagt gatcgaaaca cctacttgaa
901 ttggtttcag cagaggccag gccaatctcc aaggcgccta atttataagg tttctaaccg
961 ggactctggg gtcccagaca gattcagcgg cagtgggtca ggcactgatt tcacactgaa
1021 aatcagcagg gtggaggctg aggatgttgg ggtttattac tgcatgcaag gtacacactg
1081 gtcctggacg ttcggccaag ggaccaaggt ggaaatcaaa cgt
//