GenBank-Updates@genbank.bio.net (09/02/90)
LOCUS HUMGPD1A 4006 bp ds-DNA PRI 02-SEP-1990
DEFINITION Human glycerol-3-phosphate dehydrogenase (GPD1) gene, promoter
region.
ACCESSION M36917
KEYWORDS glycerol-3-phosphate dehydrogenase.
SOURCE Human fetal liver DNA, clones 1 and 3.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 4006)
AUTHORS Gwynn,B., Lyford,K.L. and Birkenmeier,E.H.
TITLE Sequence conservation and structural organization of the
glycerol-3-phosphate dehydrogenase promoter in mouse and man
JOURNAL Mol. Cell. Biol. (1990) In press
STANDARD full staff_entry
COMMENT Draft entry and computer-readable sequence for [1] kindly submitted
by E.H.Birkenmeier, 23-JUL-1990.
FEATURES from to/span description
pept 3965 / 4006 glycerol-3-phosphate dehydrogenase, exon 1 (EC
1.1.1.8)
binding 3860 3868 Sp1 binding site
site 3688 3701 FSE 2
site 3708 3719 FSE 1
site 3726 3739 FSE 2
site 3746 3758 FSE 1
signal 3894 3900 TATA box
BASE COUNT 889 a 1076 c 969 g 1072 t
ORIGIN
1 aagcttgcag acccctcagg tagcagcagg acctgtgatc ttggcccctt ggatctgaga
61 tggtttttgc atctttccag gagagcctca cattcttctt ccaggttgta tcacccccga
121 gttagcatat cccaggctcg cagactcaac acagcgaggg tgggagacag ctgggcacaa
181 agggggaatt ccgttcagca tgggctctaa acccacagaa ctgacaaagc ccctgcttcc
241 ccaccccctc ctcaggctcc gcgagcacac ccccaccccc aaatccctcc ctgttctaca
301 ctggggacag cagaatttct ccccgtcttc cccttcctgc cattttccct cccttaaagt
361 tgacactgga caaccttggg gcagctgagc cctggccgcc tcctggctgg aaccatgaga
421 aggaagctca gtacttccca cagtgtccct gttgataact gtttttatta actgaattgt
481 ttttttcatg gaccaaactt ttttttgtac tgtcccctta ttgatgttac ccagttttaa
541 taaaagaatc ttctgaagga tgggtcctcc tacctactgt gagagagctc ttccctgagc
601 tcttcttcct tcaataccat tagccacgct tgtagtgttt gttcatttta tttgacaagt
661 atttattgag cacctgctat gtgctagttg tgatgctaga cacgggagat aaagtggaaa
721 atgagatttc tacttttgtg gacctcaggg tcttacctta agagattgct gtctgcccca
781 gtggtccaag cagcctagtt gctggttggg attattgggc ttcaccactg gatcttaaga
841 gccctttccc gacttgctag gcaggtacta acaggttggt ggcagtcatt ttcccccttg
901 tccatctgag ctccccagag cacttgttgg ctggagtgag ccatagatgc ccgtgatccc
961 ttaggtttga cgaacctgag ccgcctttgg aggagtttca cttcttcccc agggcttctg
1021 tttagatgtg ggcaggatct ggacgaccaa agacattttt gctttttgtg cctgctactc
1081 tttttttttt ttttttttta gacggagtct cactgttgcc caggctggag tgcagtagtg
1141 cgatcttggc tcactgcaag ctctgcctcc tgggttcacg ccattctcct gcctcagcct
1201 cccgagtagc tgggactaca ggcgcctgcc accatgcccg gcaatttttg tattttttag
1261 tagagacagg gtaaaccgtg ttagccagga tggtctcgat ctcctgacct cgtgatccgc
1321 ccgcctcggt ctcccaaagt gctgggatta caggtgtgaa ccaccgtgcc cagcctgtgc
1381 ctgctactct aaggttccgc tttcatggtt caaataagag ttcagttttt gtttgcctgt
1441 tttgagatgg agttgtgttc ttgttcccca ggctggagtg caatggcgcg ttctcggctt
1501 actgcaacct ccgcctccca ggttcaagtg attttcctgc ctcagcctcc tgagtagctg
1561 gttcttaaga gcaccatgga agttctgtgt tgtcatcctc atactgtaga caactagccc
1621 ctccttggca gagtttggaa gacagctcag gagggattcc cattagcaat cacttgaaac
1681 tcgcctgcag ttctgcctgc ttcccacttg gaggctcatg acttttttcc tttgtcatta
1741 tgcaagaatg gggtttggaa tataggatca gagtacaacc actttccaaa gttgtagttt
1801 aaaaattatc ctttgcctgt ttggatggga acattctagt attgcctgtt caatatatgt
1861 aatcaaaccc accaaaaaat ccaaccactg ttcctactcc ggaacttggg gtttatcaga
1921 cttgagaagg gaaagcagag aggagtggtt gggccgataa ctaggagtgg agaaaattga
1981 tgtcaaggac attgaaatgg catctgtttt tacccaggct aattacatgt gtaatgaatg
2041 gctgatgaac cattattaat ttcaagcgaa atctacagtt tgcctctggg aaaagagctc
2101 tagtgataca gataacttcc tgtgatgagc cgattctgaa tctctgcacc ctctttattc
2161 ccatgtaaat gagcacattc ttagtctcca cactatctaa aatgattgta ggggcaaaat
2221 gagagaggga agcatttagg caaaaacaag ggggttattt tatgcataaa catccattct
2281 ttggggctcc catcatttgt gccagggaca gaagcatcct ttctcttcca tcacccgtaa
2341 tcagtgctcc cagctggcag cctggcactg gagccttcat ctcagtgcca gtgcaataaa
2401 ggagtggtct gtgggaggct gtttctgtat taggtataac attgtgctaa gaaaaacagc
2461 caactactga tttcatgtcc gtttccctat gggaaattac tggccatgga aggagaatat
2521 ggttggtttt ttcctgggca gtccccggaa cttagaaagc catttctccc cagtcttgac
2581 ctcctgcctg cttactccta cccatgggtt gcacacagac tcccctgtag cccagtgctt
2641 gttaccagtt gctggccagc aacagcccag ggggatggca acacccacct agccgtctgc
2701 caagccagga ggtcagcaca tgagcacaca gtggtgtctg ccctctaggc caaggtgcac
2761 agtgttagga gcctcttgct ccactctcca gatcagcctg gaaaccagag cttccctcgt
2821 cttagacaaa cagatggccg tgggcgatgc agagccctga actgctgagg gtgctccttc
2881 cattctcgcc cttccccaaa aaacatacac caaacttacc cccaatcaca gcatctgaga
2941 ccacaaagcc ccacggacac agctgccccg ggtactgcct gccttcccct tttctggcct
3001 ctgcaaacta gccattcacc tgatgaagcc cctggggcag taccttggaa acccctgaga
3061 ggaggagttg aaggaggctc aaagcctttc aaggacagtg tgcactctgc ctgcctccta
3121 ttctctcctg tcctcttaag cccagagtct acaacaaaat tgtgtaccgc aattctcaga
3181 gctctctaac tttaaccttt cccaccttcc ctagaacaca tttttgggtg gggatcatct
3241 gagaggccca tggatgagtc cccaagatga cctctgtggg tgaccaagac aatcttgtct
3301 tttgaggcac ctggagtctc tcatcctttt ttgagctggg ctgtcctcaa agcaggccct
3361 tacctcttat gtggcctcat ctttagaggt gggaagtggg cccacatccc ccaccccagc
3421 cctgcagtgg agctagcgtg ggcctgctgg aggacagaac tgtggaacag ggtcctgtga
3481 ggatatgtgg cagggttggc ggggggatag ggggtcatgg aggagcctac ctctgaaaag
3541 cattccccta gctgctactg aagctaaata caatttattt catgctgggg gacagaaagg
3601 agcaagggag agcagtcacc tgctccttat ctgggctatt ttcttagcag acctcaaaat
3661 gagaccatgg tgggaagctg ggctggggcc aagggaagaa gcttgccagc actgtcagcc
3721 gatgagccca ggagaaaaag ctgggcctag tctctgcccc attcctgttc cacacctgtc
3781 tgtacccctg tctctccttt ccctggctct gccagactct ctatctccct gggcgccagc
3841 ctccccaccc acccctggag ggcggggctt ggctgcaccc acgtgtggtg gagttaaatg
3901 ctcctagccg gcagaggagc tagggagtgt ggcactgagc cggctcaggc agagacgcgg
3961 caccatggct agcaagaaag tctgcattgt aggctccggg aactgg
//GenBank-Updates@genbank.bio.net (09/07/90)
LOCUS HUMGPD1A 4006 bp ds-DNA PRI 07-SEP-1990
DEFINITION Human glycerol-3-phosphate dehydrogenase (GPD1) gene, promoter
region.
ACCESSION M36917
KEYWORDS glycerol-3-phosphate dehydrogenase.
SOURCE Human fetal liver DNA, clones 1 and 3.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 4006)
AUTHORS Gwynn,B., Lyford,K.L. and Birkenmeier,E.H.
TITLE Sequence conservation and structural organization of the
glycerol-3-phosphate dehydrogenase promoter in mouse and man
JOURNAL Mol. Cell. Biol. (1990) In press
STANDARD full staff_entry
COMMENT Draft entry and computer-readable sequence for [1] kindly submitted
by E.H.Birkenmeier, 23-JUL-1990.
FEATURES from to/span description
pept 3965 / 4006 glycerol-3-phosphate dehydrogenase, exon 1 (EC
1.1.1.8)
binding 3860 3868 Sp1 binding site
site 3688 3701 FSE 2
site 3708 3719 FSE 1
site 3726 3739 FSE 2
site 3746 3758 FSE 1
signal 3894 3900 TATA box
BASE COUNT 889 a 1076 c 969 g 1072 t
ORIGIN
1 aagcttgcag acccctcagg tagcagcagg acctgtgatc ttggcccctt ggatctgaga
61 tggtttttgc atctttccag gagagcctca cattcttctt ccaggttgta tcacccccga
121 gttagcatat cccaggctcg cagactcaac acagcgaggg tgggagacag ctgggcacaa
181 agggggaatt ccgttcagca tgggctctaa acccacagaa ctgacaaagc ccctgcttcc
241 ccaccccctc ctcaggctcc gcgagcacac ccccaccccc aaatccctcc ctgttctaca
301 ctggggacag cagaatttct ccccgtcttc cccttcctgc cattttccct cccttaaagt
361 tgacactgga caaccttggg gcagctgagc cctggccgcc tcctggctgg aaccatgaga
421 aggaagctca gtacttccca cagtgtccct gttgataact gtttttatta actgaattgt
481 ttttttcatg gaccaaactt ttttttgtac tgtcccctta ttgatgttac ccagttttaa
541 taaaagaatc ttctgaagga tgggtcctcc tacctactgt gagagagctc ttccctgagc
601 tcttcttcct tcaataccat tagccacgct tgtagtgttt gttcatttta tttgacaagt
661 atttattgag cacctgctat gtgctagttg tgatgctaga cacgggagat aaagtggaaa
721 atgagatttc tacttttgtg gacctcaggg tcttacctta agagattgct gtctgcccca
781 gtggtccaag cagcctagtt gctggttggg attattgggc ttcaccactg gatcttaaga
841 gccctttccc gacttgctag gcaggtacta acaggttggt ggcagtcatt ttcccccttg
901 tccatctgag ctccccagag cacttgttgg ctggagtgag ccatagatgc ccgtgatccc
961 ttaggtttga cgaacctgag ccgcctttgg aggagtttca cttcttcccc agggcttctg
1021 tttagatgtg ggcaggatct ggacgaccaa agacattttt gctttttgtg cctgctactc
1081 tttttttttt ttttttttta gacggagtct cactgttgcc caggctggag tgcagtagtg
1141 cgatcttggc tcactgcaag ctctgcctcc tgggttcacg ccattctcct gcctcagcct
1201 cccgagtagc tgggactaca ggcgcctgcc accatgcccg gcaatttttg tattttttag
1261 tagagacagg gtaaaccgtg ttagccagga tggtctcgat ctcctgacct cgtgatccgc
1321 ccgcctcggt ctcccaaagt gctgggatta caggtgtgaa ccaccgtgcc cagcctgtgc
1381 ctgctactct aaggttccgc tttcatggtt caaataagag ttcagttttt gtttgcctgt
1441 tttgagatgg agttgtgttc ttgttcccca ggctggagtg caatggcgcg ttctcggctt
1501 actgcaacct ccgcctccca ggttcaagtg attttcctgc ctcagcctcc tgagtagctg
1561 gttcttaaga gcaccatgga agttctgtgt tgtcatcctc atactgtaga caactagccc
1621 ctccttggca gagtttggaa gacagctcag gagggattcc cattagcaat cacttgaaac
1681 tcgcctgcag ttctgcctgc ttcccacttg gaggctcatg acttttttcc tttgtcatta
1741 tgcaagaatg gggtttggaa tataggatca gagtacaacc actttccaaa gttgtagttt
1801 aaaaattatc ctttgcctgt ttggatggga acattctagt attgcctgtt caatatatgt
1861 aatcaaaccc accaaaaaat ccaaccactg ttcctactcc ggaacttggg gtttatcaga
1921 cttgagaagg gaaagcagag aggagtggtt gggccgataa ctaggagtgg agaaaattga
1981 tgtcaaggac attgaaatgg catctgtttt tacccaggct aattacatgt gtaatgaatg
2041 gctgatgaac cattattaat ttcaagcgaa atctacagtt tgcctctggg aaaagagctc
2101 tagtgataca gataacttcc tgtgatgagc cgattctgaa tctctgcacc ctctttattc
2161 ccatgtaaat gagcacattc ttagtctcca cactatctaa aatgattgta ggggcaaaat
2221 gagagaggga agcatttagg caaaaacaag ggggttattt tatgcataaa catccattct
2281 ttggggctcc catcatttgt gccagggaca gaagcatcct ttctcttcca tcacccgtaa
2341 tcagtgctcc cagctggcag cctggcactg gagccttcat ctcagtgcca gtgcaataaa
2401 ggagtggtct gtgggaggct gtttctgtat taggtataac attgtgctaa gaaaaacagc
2461 caactactga tttcatgtcc gtttccctat gggaaattac tggccatgga aggagaatat
2521 ggttggtttt ttcctgggca gtccccggaa cttagaaagc catttctccc cagtcttgac
2581 ctcctgcctg cttactccta cccatgggtt gcacacagac tcccctgtag cccagtgctt
2641 gttaccagtt gctggccagc aacagcccag ggggatggca acacccacct agccgtctgc
2701 caagccagga ggtcagcaca tgagcacaca gtggtgtctg ccctctaggc caaggtgcac
2761 agtgttagga gcctcttgct ccactctcca gatcagcctg gaaaccagag cttccctcgt
2821 cttagacaaa cagatggccg tgggcgatgc agagccctga actgctgagg gtgctccttc
2881 cattctcgcc cttccccaaa aaacatacac caaacttacc cccaatcaca gcatctgaga
2941 ccacaaagcc ccacggacac agctgccccg ggtactgcct gccttcccct tttctggcct
3001 ctgcaaacta gccattcacc tgatgaagcc cctggggcag taccttggaa acccctgaga
3061 ggaggagttg aaggaggctc aaagcctttc aaggacagtg tgcactctgc ctgcctccta
3121 ttctctcctg tcctcttaag cccagagtct acaacaaaat tgtgtaccgc aattctcaga
3181 gctctctaac tttaaccttt cccaccttcc ctagaacaca tttttgggtg gggatcatct
3241 gagaggccca tggatgagtc cccaagatga cctctgtggg tgaccaagac aatcttgtct
3301 tttgaggcac ctggagtctc tcatcctttt ttgagctggg ctgtcctcaa agcaggccct
3361 tacctcttat gtggcctcat ctttagaggt gggaagtggg cccacatccc ccaccccagc
3421 cctgcagtgg agctagcgtg ggcctgctgg aggacagaac tgtggaacag ggtcctgtga
3481 ggatatgtgg cagggttggc ggggggatag ggggtcatgg aggagcctac ctctgaaaag
3541 cattccccta gctgctactg aagctaaata caatttattt catgctgggg gacagaaagg
3601 agcaagggag agcagtcacc tgctccttat ctgggctatt ttcttagcag acctcaaaat
3661 gagaccatgg tgggaagctg ggctggggcc aagggaagaa gcttgccagc actgtcagcc
3721 gatgagccca ggagaaaaag ctgggcctag tctctgcccc attcctgttc cacacctgtc
3781 tgtacccctg tctctccttt ccctggctct gccagactct ctatctccct gggcgccagc
3841 ctccccaccc acccctggag ggcggggctt ggctgcaccc acgtgtggtg gagttaaatg
3901 ctcctagccg gcagaggagc tagggagtgt ggcactgagc cggctcaggc agagacgcgg
3961 caccatggct agcaagaaag tctgcattgt aggctccggg aactgg
//