GenBank-Updates@genbank.bio.net (09/13/90)
LOCUS HUMBCRA3 200 bp ds-DNA PRI 13-SEP-1990
DEFINITION Human chronic myelocytic leukemia c-abl oncogene breakpoint cluster
region (bcr) DNA, exon a2.
ACCESSION M25949
KEYWORDS break point cluster region; c-abl oncogene;
chronic myelocytic leukemia.
SEGMENT 3 of 3
SOURCE Human fibroblast cell line K562, cDNA to mRNA, clone pV1-3.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 200)
AUTHORS De Klein,A., Hermans,A., Bootsma,D., Grosveld,G., Heisterkamp,H.,
Stam,K. and Groffen,J.
TITLE The role of the Philadelphia translocation in chronic myelocytic
leukemia
JOURNAL Ann. Clin. Res. 18, 278-283 (1986)
STANDARD simple staff_entry
FEATURES from to/span description
pept + 16 > 200 bcr/c-abl oncogene protein, exon a2
IVS < 1 15 c-abl intron a2
BASE COUNT 53 a 53 c 50 g 44 t
ORIGIN About 2.5 kbp downstream of segment 2.
1 ttcctttctt ctcaggtgaa aagctccggg tcttaggcta taatcacaat ggggaatggt
61 ttgaagccca aaccaaaaat ggccaaggct gggtcccaag caactacatc acgccagtca
121 acagtctgga gaaacactcc tggtaccatg ggcctgtgtc ccgcaatgcc gctgagtatc
181 tgctgagcag cgggatcaat
//