GenBank-Updates@genbank.bio.net (09/13/90)
LOCUS HUMCMLCABL 468 bp ss-mRNA PRI 13-SEP-1990
DEFINITION Human chronic myelocytic leukemia c-abl oncogene breakpoint cluster
region (bcr) DNA, partial cds.
ACCESSION M25946
KEYWORDS break point cluster region; c-abl oncogene;
chronic myelocytic leukemia.
SOURCE Human fibroblast cell line K562, cDNA to mRNA, clone pV1-3.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 468)
AUTHORS De Klein,A., Hermans,A., Bootsma,D., Grosveld,G., Heisterkamp,N.,
Stam,K. and Groffen,J.
TITLE The role of the Philadelphia translocation in chronic myelocytic
leukemia
JOURNAL Ann. Clin. Res. 18, 278-283 (1986)
STANDARD simple staff_entry
FEATURES from to/span description
pept < 1 > 468 bcr/c-abl oncogene protein (AA at 1)
recomb 109 110 breakpoint cluster region end/ c-abl oncogene
start
BASE COUNT 126 a 120 c 117 g 105 t
ORIGIN
1 gtccacagca ttccgctgac catcaataag gaagatgatg agtctccggg gctctatggg
61 tttctgaatg tcatcgtcca ctcagccact ggatttaagc agagttcaaa agcccttcag
121 cggccagtag catctgactt tgagcctcag ggtctgagtg aagccgctcg ttggaactcc
181 aaggaaaacc ttctcgctgg acccagtgaa aatgacccca accttttcgt tgcactgtat
241 gattttgtgg ccagtggaga taacactcta agcataacta aaggtgaaaa gctccgggtc
301 ttaggctata atcacaatgg ggaatggtgt gaagcccaaa ccaaaaatgg ccaaggctgg
361 gtcccaagca actacatcac gccagtcaac agtctggaga aacactcctg gtaccatggg
421 cctgtgtccc gcaatgccgc tgagtatctg ctgagcagcg ggatcaat
//