GenBank-Updates@genbank.bio.net (09/13/90)
LOCUS HUMSTATH2 4723 bp ds-DNA PRI 13-SEP-1990
DEFINITION Human salivary statherin gene, exons 2-6.
ACCESSION M32639
KEYWORDS statherin.
SEGMENT 2 of 2
SOURCE Human (individuals #563, #8136,and J.F.) fibroblast, cell line
#563, DNA, clones 1-3.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 4723)
AUTHORS Sabatini,L.M., He,Y.-Z. and Azen,E.A.
TITLE Structure and sequence determination of the gene encoding human
salivary statherin
JOURNAL Gene 89, 245-251 (1990)
STANDARD full staff_review
COMMENT Draft entry and computer-readable sequence for [1] kindly submitted
by L.M.Sabatini, 03-JAN-1990.
FEATURES from to/span description
pept 302 352 statherin precursor, exon 2 (first translated
exon) /nomgen="STATH" /map="4q11-q13"
/hgml_locus_uid="LT0081T"
1532 1552 statherin precursor, exon 3
1645 1674 statherin precursor, exon 4
2728 2814 statherin precursor, exon 5
sigp 302 352 statherin signal peptide
1532 1537 statherin signal peptide
matp 1538 1552 statherin
1645 1674 statherin
2728 2811 statherin
pre-msg < 1 4309 STATH mRNA and introns
IVS < 1 286 STATH intron A
IVS 353 1531 STATH intron B
IVS 1553 1644 STATH intron C
IVS 1675 2727 STATH intron D
IVS 2848 4051 STATH intron E
signal 4294 4299 poly-A signal
BASE COUNT 1570 a 797 c 722 g 1634 t
ORIGIN About 1.8 kb after segment 1.
1 aagctttact ttcttcttta ccttcatacc cctattctct tggtctgtgt aaggtgttga
61 tttgtgtgtt actctaatgc cttagcattt ccatatcaat acactcactt ttacttatca
121 gtgtctccaa caagtctcca agtttcatga tgtcaggcaa tgggttttaa ttgtctttct
181 atctggagtg tgtctcccag tgctttggag cgtagtataa tcaataaact tttgatgggc
241 gaatcgaaga aaaaatgtga tactgaattt ccacatatgt tttcagagaa cccagccaac
301 tatgaagttc cttgtctttg ccttcatctt ggctctcatg gtttccatga ttgtaagtat
361 atcaggacat ttgaagaata tgttctcagt acctatccca agagtctctc tattccttgt
421 gttctggcat atattggtgt ttacttgaat acagctttat atgtttaaat gtttccatat
481 gaactttttt tttgtactaa cctacataag ctatataagg atttagaata aatagtcatt
541 attcatctac agacactaaa gtatatttag cttagtgtga aataaaagaa agttttactg
601 aacttcttaa atatgtggaa ctgagagctt ctaaaagtat ctttaaacat gtaatgctct
661 agacaatctg aagttagaaa tctcaggaat gaactaggtg cacttgagtg gaattcaagt
721 attagaagat gtcaaagtag aaattttcag atcattcctt gcaaaaacta acttaaaatt
781 agtatacaat tatttagcac acactttcta aaataaagct gcttattttt aactataaaa
841 caaaacttca gatctatgac atgttatgag ttcccagctt ttattgtcat ttactactat
901 gtatcactag gtaaagcact tgacttctct ggagctcttt cttctactct acttccttct
961 atttctcctg tcccttttct atgacattag taggaaactg gccatgaaag aataaaaata
1021 gttcaactta cctggtaaat tctaacagat atttcaaaaa ctaatttgat tataaaatca
1081 cagtatacca cattatttgt tataaaagga taggtgtcta aaaaataaaa aataaaaatg
1141 taaggaaaac agagaaaaac ataatgcttg tctctgtcag taaataaaag ttatgtgtaa
1201 gtagcctttg agctgctgaa aacatattct tatgaaaaaa tacaaagttt cacttttcat
1261 tcaccaatga taaccattta ctccctttta cacacaaaac aagtataaat ccaaataaat
1321 ttatatttga atatagcaca ctaattacag aaaagcatac tcttaactca ttttaaagat
1381 gtcataagca aaaatgaact aatttagtgt ctatcgatga tttgcctaca tcctgtttac
1441 tcacaactgt agctgctgag ttcatttttg tactcaatct ggaattataa cattaagata
1501 ctaactattg tctaattttc tgttttctaa gggagctgat tcatctgaag aggtgagtca
1561 ttttcattca ctggaaaact tgttttcagt tttgtcctcc ctacatttgt attgaattat
1621 taaacttttc ttcatttttc acagaaattt ttgcgtagaa ttggaagatt cggtgtaagt
1681 gttctctgat aatgctgtgt agtccaaata aattgtgttc tctgattact tattcttcta
1741 gaagaaccaa tacttatttc tcaaatatgt gtagtagttg caaaagtgtg ctttgttttc
1801 ctctatttat gatacacagg taacagtcac aaatgtattg tgtcctaaca acatttaagt
1861 tgaaactcat agtgccaacc tgaagaaacc agttactccc tgagccctca agcatcatct
1921 cctaagtaat cactttgacc taaaaaatag ttgaaattct aattctgtta attataatat
1981 atgcctcatg gagcataaag gctgataatt acacataaaa tatggtaagt ttgcaccttc
2041 tgattttttt tgacggtgat aaactcatta aattaaacag gtcatgataa atgagatagc
2101 aaatttcatt tatttaacat ttttcttaat gtatgtatct tgatgtccca gtatgttgac
2161 atataatgtc aatgtgatag ggttgcaaaa gatcccctaa ctaatatagt gaatacatgg
2221 attaaaataa caccaaataa aaagatactc taaaagggat gatggttatt tgtgttaaca
2281 gaaggaagaa gtattaagga atgtaggaat cgtaagagac agtaagctca ttaaaagagt
2341 gacttgaaga aacaccacat aagctgaatt tagtaaatgt ctccttccca taatactcaa
2401 aggtgggcaa aatggttgct gggaggtagt attttgaaga aaatttaaaa cctctttgga
2461 gtgatagcct ataatcggtg ttcctgcatg tgaaataaaa ccacaaaact gtgaacatgc
2521 agtacaaagg taaacactca atcattttta cctgctttta aaatgtgttt ataaccaaaa
2581 agaaaaatct aattgaaagt ttggaaaaaa atcttataag taatatgtaa gttcctaaaa
2641 ctttaacaat ctaagcttct aataaaaacg cttgcactgt cattatctca attttctgca
2701 attttctttc tccttgtgtg tatacagtat gggtatggcc cttatcagcc agttccagaa
2761 caaccactat acccacaacc ataccaacca caataccaac aatatacctt ttaatatcat
2821 cagtaactgc aggacatgat tattgaggta agatgggttt agtgacattt tttttacttt
2881 ctgtatcagt gctgacagtt aaaagaagaa aaacaaaaac aagacattaa accaacagca
2941 gttccagtat aagaaagcag ctgtatagct ccttgaaatg tattaattta tataaatgct
3001 tctgagataa agtctctgtc ctgctatggt tagaaggcag tgttatagag tgggggacac
3061 cagggtttgt atgctggccc tgacaactac tagtttcatg actttgaact actcctaatg
3121 ctcctgaacc tcagttttct cgtcaaaaaa ttgtgtatta tgataacact taaatgtgct
3181 ttttagaatt ggtgacactt ttgaaagaca tatcacataa aatctcttga tcagaaaggt
3241 ttgtagttat aactgcaggg cttccctgcc actaaatctg tacctaggtg ttgcttaaag
3301 ttttcactcc caaaatgcaa tctttggaga agcttccatc tgggaaccat ctgggaactt
3361 gtgagaaatt tgcattttgt accctaagta actctactga gcaattacta tagaaattat
3421 taacataatg ctaacaagaa aatatggaaa tgttatcaat ttctttttag aaagtcagtt
3481 ttacctatct ctacacaaca ttaaatgttc taaattctat gaaaaaataa tatttcaaaa
3541 caaaatagag caaactcttg gagataaggg aggattgttc tacaaagtta aaatagtcca
3601 aaggatttca attatttttc agtgcatttg ggagattata ttccaattca attctctatt
3661 gccattagtg atacagggaa gagcctgaac ttgatcccct aggttttagg taatagctga
3721 tgacatttaa tcaagaaaag atgtattgaa atattattta gaggaaatgc atataaatga
3781 aatgtgtagg ctatatttaa gtagaagaat aaaatagtat gatgattgaa aaataattta
3841 aattgtagat gctgaatgat aatttttatt tattcaggaa ccaatttaat aattgtttaa
3901 ttgtctactc tgtgtcaaat attattttgg gccctgcatt ttataaacta taattgtata
3961 taatatctac tctgtaccag gccagaatat aaatgtgttt acaggggtaa aaattttaca
4021 gataatctgt tatttttttt tttctgtgca ggcttgattg gcaaatacga cttctacatc
4081 catattctca tctttcatac catatcacac tactaccact ttttgaagaa tcatcaaaga
4141 gcaatgcaaa tgaaaaacac tataatttac tgtatactct ttgtttcagg atacttgcct
4201 tttcaattgt cacttgatga tataattgca atttaaactg ttaagctgtg ttcagtactg
4261 tttctgaata atagaaatca cttctctaaa agcaataaat ttcaagcaca tttttacatg
4321 tatgctcctt atttttctct tttctattta taggaataat gatttctttc atcatcttct
4381 ttcccagttt gactagcaca gattgaagcc cataatgtca gaggtcctta tttataattt
4441 agtctgtcat attttatatg ttacaaacat ggtactcaaa ctcacttatt attagagcta
4501 tttatgccaa gatttgattt gcccatggtt tcctttgcca caccacagtt gctaagcctc
4561 caaagcactc acatttttta tctcagtccc tgtaggtcag aagataacca ccatgtcact
4621 ctacagcagt atgtaggcac tctgcatgta aaccatctaa tgccctccat tagtttttca
4681 gcaatgactt ttattcaaga aatatttatt gaatgacccc ggc
//