GenBank-Updates@genbank.bio.net (09/14/90)
LOCUS HUMIGCTL1 2580 bp ds-DNA PRI 14-SEP-1990
DEFINITION Human Ig superfamily T-lymphocyte-associated serine esterase
(CTLA-4) gene, exon last-2.
ACCESSION M37243 X15070
KEYWORDS serine esterase.
SEGMENT 1 of 3
SOURCE Human LY67 library DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 2580)
AUTHORS Dariavach,P., Mattei,M.-G., Golstein,P. and Lefranc,M.-P.
TITLE Human Ig superfamily CTLA-4 gene: Chromosomal localization and
identity of protein sequence between murine and human CTLA-4
cytoplasmic domains
JOURNAL Eur. J. Immunol. 18, 1901-1905 (1988)
STANDARD simple staff_entry
FEATURES from to/span description
pept / 2177 + 2524 T-lymphocyte-associated serine esterase, exon
last-2 (AA at 2179) /hgml_locus_uid="LR0170S"
/nomgen="CTLA4" /map="2q33"
IVS < 1 2176 serine esterase intron last-2
IVS 2525 > 2580 serine esterase intron next to last
BASE COUNT 759 a 473 c 640 g 708 t
ORIGIN
1 gaattcgagc tcacaagttc ctttaaaaaa aattgactta agcaaatcct gggaagagtt
61 tttttgctat acaattcaag gttttaaggt cctcggattc atatacttta taaatgaatt
121 agccagcttg tttaaatgta gggaaattgt gggaagaatg ccttctttac ttaattcaag
181 gttttaaggt tctcttaatc aattctacta gctaattagc caattattta aaaataaaag
241 tttgaaattg ccaaaaaaaa aagacaagga aaaggaaaga aagaaagcca ccagtctgtt
301 tggcatacaa tacttaattg ttgcctgacc tacgtgtggg tttcagatgc agatcctcag
361 ttttcagctc ttcagagact gacaccaggt ttgttacacg gcttaaaatg atgagtatat
421 ccatgaatct caaccttatc tctctctaga ccttcttggc taagaaacca tgtagtttgt
481 atgaagtagg tactcaaaac atatttgatg atttaatttt tactggagaa gaaatattca
541 tatatgtttt cttattttta catgttttaa atatgtaaag attaaataaa cactcttaga
601 agtatttaaa tttcctaaag taaatttatc tcaaccagta acaggaccct cccaatactg
661 gaaagttgag tgtgaccgca tttagtggtg ataagtgtga gcttgcttgg ggagagggca
721 ggacatttag gatttcttaa gcttagagtc aatacaataa agattattga gtgctcactt
781 gggtgggcta taatcactgc tcacaggagt tcatgaacca caagtaaaag agtgaggaga
841 tatgattagc tcacaaataa tctttaatac agagcagaaa gtaatgaact actgcaatgg
901 agttatcaca gtgctaagga tgctcagagg gcatctctga taggcagagg tgagggttag
961 ggaaggaagc tgtagtctag ctagctagag ctgctggaat agacatgaca atgctgctgc
1021 caaactgttt tctcttctga ggacagaatg tcccgtgcaa gtggcttggt ggaagggact
1081 agtgctctaa tatagggtga tttataagca ggaaagtgtg tcctagaaat tcagaccaga
1141 gtgatagatt gaattggatc atgggggact catttgaatg ttatttattg tattgttttt
1201 gcgatcagtg ttagtaaagt gtcaaaggga ttgagcagat gagtgacatc atgcaacaca
1261 agttttgagt ttcacttgtc agactgactg gagaggggcc tggttagtta caggaaggta
1321 atttggcatg cagccactat ttttgagttg atgcaagcct ctctgtatgg agagctggtc
1381 tcctttatcc tgtgggaaaa gagaacaaag gagcatggga gtgttcaagg gaaggagaaa
1441 taaagggcag agaggcagcg gtggtgtcag ggaagcccac aggagttaac agcagggttg
1501 cctcaaccta gagaggaagc gacctggtgc cctcggctct gtggcttcct tcatctaaca
1561 acatcttcca ctctacaaca atgccaggga aggcggaggc tggtacagtg catcaagaca
1621 cagctactcc tgggtgacag aggttcaggg cagctcacta agtaggcaga agtttttgac
1681 atatactttg agagataaag caagattctg tacctcaacc ttcagaattt cccctaccac
1741 tcattatagt tccggagcta tatagctcct atcattctat cataacctta gaataccaga
1801 gaacatatca tctcatctaa ttatctctta ctatatgtga aaaaaatgaa ggacatgggg
1861 gaagtgtgac ttgccccaaa tcacatattt catggtagag ccaggtcttc tgtttgtcat
1921 atcagtgttc ttcctgccac aaccatcttg aagaatctat ttctcagtaa gaaaatatct
1981 ttatggagag tagctggaaa acagttgaga gatggagggg aggctggggg tgtggagagg
2041 ggaaggggta agtgtataga ttcgttgaag gggggagaaa aggccgtggg gatgaagcta
2101 gaaggcagaa gggcttgctg ggcttggcat gaaggagcat gagttcactg agttcccttt
2161 ggcttttcca tgctagcaat gcacgtggcc cagcctgctg tggtactggc cagcagccga
2221 ggcatcgcca gctttgtgtg tgagtatgca tctccaggca aagccactga ggtccgggtg
2281 acagtgcttc ggcaggctga cagccaggtg actgaagtct gtgcggcaac ctacatgatg
2341 gggaatgagt tgaccttcct agatgattcc atctgcacgg gcacctccag tggaaatcaa
2401 gtgaacctca ctatccaagg actgagggcc atggacacgg gactctacat ctgcaaggtg
2461 gagctcatgt acccaccgcc atactacctg ggcataggca acggagccca gatttatgta
2521 attggtgagc aaagccattt cactgagttg acacctgttg cattgcagtc ttctatgcac
//