GenBank-Updates@genbank.bio.net (09/18/90)
LOCUS MUSTNFB 2709 bp ds-DNA ROD 18-SEP-1990
DEFINITION Mouse tumor necrosis factor (TNF) gene, complete cds.
ACCESSION M38296
KEYWORDS tumor necrosis factor.
SOURCE Mouse DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 2709)
AUTHORS Shakhov,A.N. and Nedospasov,S.A.
TITLE Molecular cloning of the genes coding for tumor necrosis factors:
Complete nucleotide sequence of the genomic copy of TNF-alpha in
mice
JOURNAL Bioorg. Khim. 13, 701-705 (1987)
STANDARD simple staff_entry
FEATURES from to/span description
pept 215 400 tumor necrosis factor precursor, exon 1
910 964 tumor necrosis factor precursor, exon 2
1142 1189 tumor necrosis factor precursor, exon 3
1484 1902 tumor necrosis factor precursor, exon 4
sigp 215 400 tumor necrosis factor signal peptide
910 960 tumor necrosis factor signal peptide
matp 961 964 tumor necrosis factor
1142 1189 tumor necrosis factor
1484 1902 tumor necrosis factor
IVS 401 909 tumor necrosis factor intron A
IVS 965 1141 tumor necrosis factor intron B
IVS 1190 1483 tumor necrosis factor intron C
signal 2651 2656 poly-A signal
BASE COUNT 697 a 676 c 738 g 598 t
ORIGIN
1 cccgccctct tcccagggct ataaagcggc cgtctgcaca gccagccagc agaagctccc
61 tcagcgagga cagcaaggga ctagccagga gggagaacag aaactccaga acatcttgga
121 aatagctccc agaaaagcaa gcagccaacc aggcaggttc tgtccctttc actcactggc
181 ccaaggcgcc acatctccct ccagaaaaga caccatgagc acagaaagca tgatccgcga
241 cgtggaactg gcagaagagg cactccccca aaagatgggg ggcttccaga actccaggcg
301 gtgcctatgt ctcagcctct tctcattcct gcttgtggca ggggccacca cgctcttctg
361 tctactgaac ttcggggtga tcggtcccca aagggatgag gtagtgtctg ggcaccctta
421 ttctcgctca caagcaagac gggttaggag ggcaagaaga cagtgtgagg gaaagaagtg
481 ggctaatggg cagggcaagg tggaggagag tgtggagggg acagagtcag gacctcggac
541 ccatgcgtcc agctgactaa acatccttcg tcggatgcac agagagatga atgaacgaac
601 aagtgtgttc acacgtggag agatctggaa agatgtggcc aggggaagag gggataagca
661 agagataaaa ctcagagaca gaaatgagag aggcatgaga gataaggagg aagatgaagg
721 ggagataacg ggagatcaag cacagagggc accgcagaaa gaagccgtgg gttggacaga
781 tgaatgaatg aagaagaaaa cacaaagtgg ggggtgggtg gggcaaagag gaactgtaag
841 cggggcaatc agccgggagc ttctcctttg gggtgagtct gtcttaacta acctcctttt
901 cctacacaga agttcccaaa tggcctccct ctcatcagtt ctatggccca gaccctcaca
961 ctcagtaagt gttcccacac ctctctctta atttaagatg gagaagggca gttaggcatg
1021 ggatgagatg gggtgggggg aaaacttaaa gctttggttt gggaggaaag gggtctaagt
1081 gcatagatgc ttgctgggaa gcctaaaagg ctcatccttg cctttgtctc ttcccctcca
1141 ggatcatctt ctcaaaattc gagtgacaag cctgtagccc acgtcgtagg taagatttct
1201 ttacatgtgc cttgagaatg aaggggcatg attttggggg gggggttgag gggtgtcgag
1261 ccaggctgag aaaagacaga gctcttagag acagcacgtg agagtcagag cagtgactca
1321 aaagcaaggc atcagggggc cacccgggac ctcatagcca atgggatgtg gaaagacaga
1381 gggtgcagga accggaagtg aagtgtgggt agctgctgag gctcaggatg tggagtgtga
1441 actaagaggg tgacactgac tcaatcctcc ccccccccct cagcaaacca ccaagtggag
1501 gagcagctgg agtggctgag ccagcgcgcc aacgccctcc tggccaacgg catggatctc
1561 aaagacaacc aactagtggt gccagccgat gggttgtacc ttgtctactc ccaggttctc
1621 ttcaagggac aaggctgccc cgactacgtg ctcctcaccc acaccgtcag ccgatttgct
1681 atctcatacc aggagaaagt caacctcctc tctgccgtca agagcccctg ccccaaggac
1741 acccctgagg gggctgagct caaaccctgg tatgagccca tatacctggg aggagtcttc
1801 cagctggaga agggggacca actcagcgct gaggtcaatc tgcccaagta cttagacttt
1861 gcggagtccg ggcaggtcta ctttggagtc attgctctgt gaagggaatg ggtgttcatc
1921 cattctctac ccagccccca ctctgacccc tttactctga cccctttatt gtctactcct
1981 cagagccccc agtctgtatc cttctaactt agaaagggga ttatggctca gggtccaact
2041 ctgtgctcag agctttcaac aactactcag aaacacaaga tgctgggaca gtgacctgga
2101 ctgtgggcct ctcatgcacc accatcaagg actcaaatgg gctttccgaa ttcactggag
2161 tctcgaatgt ccattcctga gttctgcaaa gggagagtgg tcaggttgcc tctgtctcag
2221 aatgaggctg gataagatct caggccttcc taccttcaga cctttccaga ttcttccctg
2281 aggtgcaatg ccaagccttc ctcacagagc cagcccccct caatttatat ttgcacttat
2341 tatttattat ttatttatta tttatttatt tgcttatgaa tgtatttact tggaaggccg
2401 gggtgtcctg gaggacccag tgtgggaagc tgtcttcaga cagacatgtt ttctgtgaaa
2461 acggagctga gctgtcccca cctggcctct ctaccttgtt gcctcctctt ttgcttaatg
2521 tttaaaacaa aatatttatc taacccaatt gtcttaataa cgctgatttg gtgaccaggc
2581 tgtcgctaca tcactgaccc tcttgcccca cgggagccgt gactgtaatc gcctacggtc
2641 aattgagaaa aataaagatc gcttggaaaa gaaatgtgat ttctgtcttg ggatgaagtc
2701 tgcatccat
//