GenBank-Updates@genbank.bio.net (08/25/90)
LOCUS RATPAI1AA 14302 bp ds-DNA ROD 25-AUG-1990
DEFINITION Rat plasminogen activator inhibitor-1.
ACCESSION J05206
KEYWORDS plasminogen activator inhibitor-1.
SOURCE R.norvegicus (strain Buffalo) HTC hepatoma cells DNA, clones
lambda-[MZ,BL].
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 14302)
AUTHORS Bruzdzinski,C.J., Riordan,M.F., Nordby,E.C., Suter,S.M. and
Gelehrter,T.D.
TITLE Isolation and characterization of the rat plasminogen activator
inhibitor-1 gene
JOURNAL J. Biol. Chem. 265, 2078-2085 (1990)
STANDARD full staff_entry
COMMENT Draft entry and computer-readable sequence for [1] kindly submitted
by C.J.Bruzdzinski, 03-FEB-1990.
FEATURES from to/span description
pept 3586 3856 plasminogen activator inhibitor-1, exon 2
(first expressed exon)
5124 5357 plasminogen activator inhibitor-1, exon 3
6870 7064 plasminogen activator inhibitor-1, exon 4
7699 7897 plasminogen activator inhibitor-1, exon 5
9617 9717 plasminogen activator inhibitor-1, exon 6
9820 9906 plasminogen activator inhibitor-1, exon 7
10664 10747 plasminogen activator inhibitor-1, exon 8
11018 11055 plasminogen activator inhibitor-1, exon 9
pre-msg 236 11016 plasminogen activator inhibitor-1 mRNA and
introns
IVS 2536 3584 Intron 1
IVS 3857 5123 Intron 2
IVS 5358 6869 Intron 3
IVS 7065 7698 Intron 4
IVS 7898 9616 Intron 5
IVS 9718 9819 Intron 6
IVS 9907 10663 Intron 7
IVS 10748 11017 Intron 8
signal 2364 2368 TATA box
BASE COUNT 3973 a 3548 c 3617 g 3164 t
ORIGIN
1 gatccccggg tcccagaccc ctctgacttc caaggacaga agacaaggca tttggagaca
61 tagtactggg aggataagag cagagttgtg tcttcctcag agatggccaa gaacatctgc
121 ctgtccctcc cagccctaca gcctccctca gggcttccaa gcacagatga gaacagggaa
181 aaacataaac aagcaacagc tggtcctaca ggccgtggct gggcctatga gcctgagttt
241 ccagctgagg tttccctctt tcctcaacct tcccaccccc acctgactcg gttctcgggg
301 tcgccagaga aaactcgcgg gctggttgcc ctggtatctg tttactggaa attgaaaaca
361 aacaccaaac acgctgctgt gccgcccacc taagcttccc gtgattcgcc agacagctgt
421 ctccatggat actgccaagc gaacacccat cgcctataca aaagatgaca gtttgtgaat
481 ccggaggcta agagtgcccc tcctcaaccc cacccccccc cccccccccc cgccgccgca
541 ggaccacctt ggtcttttct agtccaagcc ctctctctag tcacaaaaat ctagagttac
601 aaagggtttt tgattctgtc caaccttcaa aggcacacag cctggtcctc ttaagtgctg
661 tgcaaatgtt tctctaaaga aatcgtggag ctggggcggt gtttcagttg gtggtttgtc
721 ttgtatgttg gaagtcctgg gttcgagccc ccgtacttgc ataagcccca ggtgtggtgc
781 tgtataccgg aagtctcaat aactgggagg tgaagggagg tggatcagaa tctccagggt
841 agcctcagct gtatatatat aatgaatttg aggctaacct gggctgcata cccatgagat
901 tgtccaaaaa ccacaaaaaa ctcttcagtc attcttcctc cacaggtcta agaacagaat
961 cccactatga tatatatata tatatataac atacatacta catacatact acacacatac
1021 tacacacata catactacac gcatacatac tacatgcgta catactacat gtgtgtgtgt
1081 gtgtgtgtgt gtgtgtgtgt gttctttcta tccctggccc tgtggctcca gtccagagga
1141 gaagaaacat cctctggggt ctagagagat ggctcaaccc ttgaaagcac acactgttct
1201 tgcagaggac ctaaattcta ttcccaacac ccacaacgaa tgacatgact gcctgtaact
1261 ccagctccag ggaatctgac actttccagc tttcacatgc acacacccac aagtggacac
1321 acacacacac acacacacac acacacacac acaccgcgca cgtaattaaa acgtaagaag
1381 aaagcggggc acggcggtac acacctctga tgccagcact caggaggcag aagcaggccg
1441 acctctgtga gttggaagcc agccagagct ccagcttgag ttccaggcta gccaggacta
1501 cataatgaat actctagcta aacaaacaaa aacgaatgaa caaacgaatg aaggataaaa
1561 taaaatcgta agaaaacacc tctttctgtc tcagtcatcc taggctgctc tactggtcct
1621 tgctccttga caaagctttc tgtggtaacc cctgtgctca tttgtggaaa agtctggtcc
1681 aatccagcca ccagcgcccc acccagtaca cctcaaaacc cagccacaca aggttattga
1741 cacaaagagc gagccctcag ggcaccagga gagtctggcc ccatgtgggg agtcagaggg
1801 cttcaccgaa ggcctggcgg gcacatggag ggaggaggaa aggacttgaa gttctctatt
1861 gggcttaagt ccaagaggaa ccagaactca gacaatcaca gggcacattt cgtgctctgg
1921 cactgggcag aaacccaaga gaaagccaag ccaacttttc ctggatatag gccgacggtg
1981 aacaaggggt agacagtact ggcagggtcc atagcttctc tgtgatggct gtctccaaag
2041 gacagagggt catgttgcca caggctgagg ctcaaggaag ggagtcctaa acaccaggca
2101 ctgtaggctc tgtggtaccg ccaagggtct agacgaccga ccagccaaag gcaaagggac
2161 agagatgttc cagtcaaggc aatcaggatt tgctcaatta tcccccatgc cctctcacac
2221 acgtacacac acgtgtccca gcaagttact gggagggagg gaaggagaga gggggcaggg
2281 cgggcgagca gcccagacat ttccagagtt agaaggtggg tggggctgga acatgagttc
2341 atctatttcc ggcccacatc tggtataaag ggagcctgca gccagggaca gagcacagct
2401 ggatcaggct gctgcagatc cccgagagct ttgtgaagga ggaacgctgc acacccgcct
2461 cccgcagcac acagccaacc acagctgagc gacacgcaac aagagccaat cacaaggcac
2521 ttccgaaagc tccaggtagg agaaaagctt tctctctctc tcaccttagg ctttaaatga
2581 aagtaggaaa catcccttcc cagaggtctc cgtctgtcac cctcgttttc cctcggttcc
2641 cttccactct tttctggaac tctgcagtcc gccctagccc aaccaggacc acaggtggtc
2701 gagaaagatg gtcaaactgc gtttccaacc ctgtatccca gaagcgaaca cattgtcttt
2761 cagtcactct ccagcaaacc tcccctttat caatttagca aaggggcttt acttttaaag
2821 atttatttat ttattatata taagtacact gtagctgcct tcagatacac cagaagaggg
2881 catcggatct ctttacaaga tggttgtaag ccaccatgtg gttgctggga attgaactca
2941 ggacctctgg aagagtaatc gggtgctctt aaccgctgag ccatctctcc agcccggggc
3001 tttactttta aaaagaaagt tgcatttata tgtgtatgta tgtgtgtgtg caaattcgtg
3061 tatcacacaa atattcgtgt tcaagtgtga aaatcaggaa acaactttca ggggtcagct
3121 cccattttaa gccaaaagtc gtcactgtcc aaaggtctct gagccccacg gaagggacgg
3181 gagacgcaca ggaggagttt ttctaagatt cactcaggtt aaaaaaaaat gaggacagct
3241 tatgttaaaa atcaaatagc atctatgggc agtaattcat gcctgtaatc acagcatttg
3301 ggagaagcga aacaggagtg tcctgagttc aagaccagcc ctgattatgt agcaaacaag
3361 actctcagaa aaaaattaaa agaattgtgt ggaggtagaa ggagatgagc tcattatcca
3421 attgcattat ggggtcttaa tgaatgtgaa cttaaccaga ctggactctt acaggctaga
3481 ggcaaacaca gagagcccag tccacgactg aggaagcaac atatcccctt ctggacagtc
3541 ttccagaagg atctccttat tggattctct tctatttatc ctaggatgca gatgtcttca
3601 gccctcactt gcctcaccct gggcctggtt ctggtctttg ggaaagggtt cgcttcaccc
3661 cttccagagt cccatacagc ccagcaggcc accaacttcg gagtaaaagt gtttcagcat
3721 gtggtccagg cctccaaaga ccgaaatgtg gtcttctctc cctacggcgt gtcctcggtg
3781 ctggctatgc tgcagctgac cacagcaggg aaaacccggc agcagatcca agatgctatg
3841 ggattcaata tcagtggtaa gagatgggct agagggagac aggtgagagg gagacaggcg
3901 agaaagtaaa gatgtgctca cagaccaggg tccagagaaa cagagaaggc agggaaagct
3961 gctgcaacat caccaagtct actcacgtcc agccacagcc cagagaccac ccattttctc
4021 tcccactatt gggtcagttg accttgactt gtaccagcca gcgggttcaa ctcatgtgag
4081 cctggtgctg ggatatagtt tgcctagcat gcacaaaggc ctgggctcca ttcccaaata
4141 gagtgaaact ggaaatggtg atgtagaacc gtgaccacgt tctttgggaa gtggaggcag
4201 aagggtcagg tgttcaagct catattggct agtatcgagt tcagcgccag cctagattac
4261 gtgagacctt taaaaaaaaa taagggaggg ggcaaaacaa aacacatggt ctcaactctt
4321 ataaaccttg gttttattac ctatgaatag ggaacaagaa tgtttcccac ccaggctgag
4381 taaatatgta ataggattat gaattactcg atatccattg atataagacc aacctagcta
4441 ggtacggtgg tagagcctgt aattgcgctt aagaggctaa gagaggttga ttatgaagtc
4501 aaggccagcc taggctacat agcaagctcc actccaggct gagctataga gcaagccctg
4561 tcacaaacca aatagaagag gaagccaggc agagtgtctc gtgccaggat tcccagcagt
4621 tgtgaggcct gttagaggga ttgttataat atataagggg gtgtggggaa gaagcaaact
4681 aaagtttata atttaagaac aggatattca aatgcaaaga aaagattggg agctgagact
4741 tgaaagaagc tactaaacag atacgttgag gctgactgtg gatgacacac cctaatccca
4801 gtacaggcag aggcataagg caagagattt cctgttagct tccaagacat ctaggactct
4861 atagtgactg gtgaagcagt ctggcttaca ctgtgagagt ctcctcaggg aggggtgggg
4921 agaagagaag aaggaaggaa gaggagagga aagaatggga gacagtcagg catggcagtg
4981 cacatcttta gtcccagcac tcagagcatt ggaagagcca catgtgcctg gacaggggta
5041 gggtgctcct tgggaaacct ggcccagctg gaagcccttg gctcaacacg aggctaatgg
5101 atcctgtcct gatatctctg cagagagggg cacagctcct gccctccgaa agctctccaa
5161 ggagctcatg gggtcatgga acaagaatga gatcagtact gcggacgcca tctttgtcca
5221 gcgggaccta gagctggtcc agggcttcat gccccacttc ttcaagctct tccggaccac
5281 ggtgaagcag gtggacttct cagaggtgga aagagccaga ttcatcatca acgactgggt
5341 ggagaggcac accaaaggta ggcctcaagg aaagcaggcc catcccaagg gaagggagca
5401 gaggagggga acttggtgtc aaattcacat atctccggct ctcccttaca gctttgtctt
5461 tggggataaa agacaaatgc ctcagaaaac aaagcaaaat ggctaatgtt tgtgctatgg
5521 tgctgaggat gctcagagcc agggcctcat gcatgctggg taatctacac taccactgag
5581 ccacgccccc agtccctccc tggaggattc taggcaggtg ccactaccac tgagcctcgc
5641 ccccagtccc ctccctggag gattctaggc agggactcta ccactgagcc acgcccccca
5701 gcccctccct ggggattcta ggtccaggga ctctaccact gagctgtaac ccaaaactgt
5761 gtttatcttg gtaaggcttt gttataagca cacagtgctg ggtgtaatgg gtcatatctt
5821 gcaggacagt tcatgaagtt tggggttagc ccgaactaca taagcaagat actgctaccc
5881 tcccccccca cacacccctg caaaagaaaa cgtaaaagag cacagggaca aaaccaacca
5941 actaaagaca gttgcagtac ataagctgcc ccacaaacca aacaaacaat acaaaaccta
6001 gacccaaacc caccaggacc agtcgaggtg gctccatggg tacgtgctct tcctgtagag
6061 ctggtgatct gaatttgatt cctgaagcca cagaaatgtg aaggagagaa tcagttccac
6121 ataagttgcc ctctgacctc ccgcttgcgt gctcgccccc acccacggac tttatacctc
6181 ccgcccaccc cccacaatag taataacctt taaaataaat aagcaaaacc aaaatcaaca
6241 tgaaaggcat caaaaaaaat gaaaggcatc actgacaata agaacgtcag taactgtatt
6301 ggggggttgg ggttgggggg gacaaaagga aaagaagaga caagggaagt cggagcttct
6361 cttttttttt tttttttttt tttttttttt ggttcttttt ttttccggag ctggggaccg
6421 aactcagggc ctaggcaagc actctaccac tgagctaaat ccccaacccc aagacggagc
6481 tttctaattc tgatactaaa atggatccca gagccaagga aaacgtgctg aagccagggc
6541 tgtggctcag gcctatcatc ccagctctta gaaagctgag gcaggaggat tatcatgaac
6601 tcaaggccac cctaggctgc aaagtgaaca ttggactagg ctggactata aaaggggggt
6661 taggggggta gaagggaggg aaggagggga atagggagta agagggagaa aaggagggag
6721 ggctgaaagg catccctttt gttctactta agcatcacag ttctttgtgt cccttcacca
6781 tacatccatt taagagctgg gaacggaagg gaaaatatct cagatgctta aaacccattg
6841 cgcttcttga tcgccttgct tttccttagg tatgatcagt gacttactgg ccaagggggc
6901 tgtaaatgag ctgacacgcc tggtgctggt gaacgccctc tatttcaacg gccaatggaa
6961 gacccccttc ttagaggcca gcacccacca gcgcctgttc cacaagtctg atggtagcac
7021 catctccgtg cccatgatgg ctcagaacaa caagttcaac tacagtgagt ccaagatccc
7081 cagaccccac ctctcacaac tacagaccca gggcacgagg gagggaggac ggcagcagag
7141 gaggtggaca cacccaagtt attacaaaga cgtaccaagc aggagatact gagatagttc
7201 aagtagggga gaggggagga cagtttcttc ttgaattaga tagtctgcca gaccacatcg
7261 gctcaacaga cccttgagcc tgtctcttct cttaaggtct ctctagtgtg attatctagg
7321 gccaaggagc cagctagggt aaggctgtgc aggagttggg tgagcatgag aacgagttag
7381 tggctggagt cagacagaaa taatgaagat caagagggag aaagtaggca ggaagggtgg
7441 ggatgtggct taaggagaac gctcaccagt cttagtgaag ccctggggtc catgctcagc
7501 tcataaacca gttacggtgg ataagtcctc ggtcgtctac attgctagtt cagaaaagag
7561 aggagaagag agcctttgaa cgggatgtag agcctgacct tctagaagga gagaagggga
7621 gagaagcagg gaaagctggg aagacagcca catgagtcag agccgactcc aagcgccgcc
7681 atcttggtat ctccccagct gagttcacca ctccggatgg gcacgagtac gacatcctgg
7741 aactgcccta ccacggcgaa accctcagca tgttcattgc agcacccttt gaaaaagatg
7801 tgcccctctc cgccatcacc aacattttgg acgctgagct catcagacaa tggaagagca
7861 acatgaccag gctgccccgc ctcctcatcc tgcctaagta agccgtccca ttcgccaacg
7921 ccctaatccc gacacccacc acccctccta aagccactgt ccccttggga gtttcccaga
7981 tgggtaatgc ccacagggaa gggacatgcg tgggaggctg atgggaaacc tcctagcctg
8041 gctttgatta tggtttctaa tttcatcatc cttgtgcctg tttctactgt tggagaaaca
8101 cgtcccacat agaccatgca cagaatactc agtaagaatc aaccaaagta gaggggagtg
8161 gcacaagcct ctaaccccag tatcagactg caagattgct gaagatgtag cttagttagt
8221 tcatgcatgc tgggctagcg ttcaaatgca atactacata ggccagtcat ggtggtacaa
8281 actcgtaatc ctagcccaag aggataatga gttcaaggcc aacctgggtt agatacagca
8341 agaccctatc tcataaggga tagggggctg tcagggaaag agctggagtt gtcggggttc
8401 ttcctcacgc gcacagagcc ctaatccccc agcaccacgt gaaccagtaa tgatggtaca
8461 cagctacaat ccctaatctc atcactaggg gcggacggag ttcaaggatc atccttgttc
8521 tactggatca cgcaagaccc atcttaaaag tcagccgaag aggagctaga ggaggaaggg
8581 ggcctctgaa tcgttctaca ctcatttgta aatgtctcca atctcaaccg cccagccccc
8641 tccttccccc acccacaaac aatgaaaggc atcaattccc agagggcaga ggagacttcc
8701 aaaaacaaat ttttcttttc ttttttctct ttcccctaat ccttctgcag aatcaaaagg
8761 ggtggagagg gctgtggtcg ggtaattcca gaattacagg gaagctcccg gcccagactt
8821 cccccgtaaa ctccaagata gcaaaaatgc caggcttgga gacagaggag aattgagttg
8881 ctttagagac tagaccttct gctactgtct ttctctctca tcaagatgaa gataatgagt
8941 catgccctgg tgggaagcag aggggggccc cccaaagtct cattctcgtg cgctcaaaag
9001 cagcctgcag accacagtta gctcctacac cctcgagagg gagaatgtga acctgtcccc
9061 tcctgcagtc aaacggaata caattatgtt aaaactactg tcatatttga ggaaagccat
9121 tagtcacgga ttcgaggggg cggaaagatt gaacaatgtt cattaatatt agaagtttct
9181 ggcaaggagg aaaaataggc cagacctcct agccaaatga agtttcaaag acttctaatg
9241 ccgtactagg gggtggaggt aggaggatca gaagttcaag gtcagggctg gggtgggtat
9301 aattgagctg tgtagagtgc ttgcctgatt tgttcaaagc cccgggttca accccagggc
9361 tatataaacc agcacggtgg catacacctg taaattctag cactcaggac atagaggcag
9421 gaggatcaaa atcatctttg gatgcattaa ggaatttggg gctagcctgg gctacatgag
9481 attcagtgtc aagacaaaac aaaaaggcag acctctttcc ttcatgctca tgtccatgtc
9541 ctagagagat ccgaaggtcc tgggagaagc agcatgtgag agccaaacta acactgtccc
9601 ctgttcctgc ccataggttc tctctggaga ctgaagtgga cctcagaggg cccctggaga
9661 agctgggcat gactgacatc ttcagctcaa cccaggccga cttcacaagt ctttccggtg
9721 agaggcgatc cccctcattt tcttgattcc atgagtcaag gtttccctca gaggatagag
9781 tggaggctaa tctgtccttt gggtcccgct ctatttcaga ccaagagcag ctctctgtag
9841 cacaagcact acaaaaggtc aagatcgagg tgaacgagag cggcacagtg gcgtcttcct
9901 ccacaggtga gtgtggctct gcccgtgtcc gcccacctcc tgggatgaca gtcactacca
9961 ccacccccaa cccccacagg aaagctagtg ccagcccagt ctgcaccctt tcccaaaccc
10021 atttctcagt ggaaaatgga tccacttgcc ctgcaactct gctccctcat ctatggctct
10081 tgagatccca gtatatgatg aggaccccca aagaaagccc gaggtgttgt cacagtggga
10141 gtgaacttaa aggatgtgct tagcggtgag ccctaaatat gtttatgact gatggaaaac
10201 tggggctcag aggaagtctc aaaactttag agccaatgtc caggaacaaa gaaagcctga
10261 agccaagcac agtggtacat cctcaggaag ctgaggcaga aggatgcagg ttcaaaaacg
10321 cagggtcctg aaaaccaagg acagggagat atgagaggct gggggcgtgg cttagtggta
10381 gagcccctac ctagaatccc ccagtgaggg gctggggcat ggctcagtgg tagagcccct
10441 gcctagaatc ccccagtgat gggctagggg ggggctcagc cataatactc ttgctctagc
10501 atgccggaag ctctgggttc cattccccac tactagtttc ttttaagcca cctgaaagtc
10561 atctcgcaat gctgctgtct gatagactgg tgtcactaga tctcctggga tcactccagt
10621 gataatatcc cccaaccata acatattgtc tcttttcttt cagccattct agtctcagcc
10681 cgcatggccc ccacggagat ggttttagac cgatcctttc tctttgtggt tcggcacaat
10741 ccaacaggtg agcagaaccc tatagcattc tcctgtcctc aaggctgtac taggaaaatt
10801 attatatacc tgcccaccat gtagacatcc cccaagcccc tagggactct gcaaaggttc
10861 agaaactcag ctccgttcct tcctgagcac tctgtcacag cccacgcagg tccaggaccc
10921 cagtcctaac ttagtcaccg gggaagctgt gacccctggc aactcactca cctccttaga
10981 gctcagttct caactgtcat gcttcttctg tcctcagaga caatcctctt catgggccag
11041 ctgatggagc cttgagagtg ggatgagaag ctcttccttt gggacaaaac tggacgtgtt
11101 ataagcagag actctgaaga aaagaattgt tttaaggact ctttggggag aaagagaagg
11161 cctttctttc ttaccccggc actggtaaat ctttccaacc agcctcccag acctcagact
11221 ctcgaagagg aaagagtcta actccctcac tagggaccta tcttactaag gtctcatcca
11281 accatagaac tcacagaatc tggatctgcc cagcattcag cctttggacc cagttcccac
11341 caaggcccca gcagggccaa cccactacgc cttcactcag caaagtcttt tgtgttccag
11401 tcacactctg ggtacctctt gtatcgtcct ccattgctat gaaggatgac ccaggccaaa
11461 ggaagaagca ctgtcctatc tcaaggtcca ctgtggaaat gaacaccttg cccatcccca
11521 aggggcagca gatagacaga tcgaatgatc gcccgatatc aagccttctc ccagctcccg
11581 tcctgccctc ccttccctga ccaggcgctt gtgttatttc agagtgtaga tgacttgttt
11641 acagcttttt tcgacccaca aacttttctc attttgaaag cgtgaaagaa aggtcagatg
11701 tgcacgtgcc ttgctcttta tcctgggtct ccctgtgagg ggagaggggt cctggggaga
11761 ttccaggggt gtgattgaat atttatcttg tttatcttat acgtttgttg gggagaagaa
11821 gcactattaa ggagaaagcc ttttatttaa accatggcat atggtgtccc atttggggtc
11881 tgtatccctg tatgtcaggg aggcatcact ccacaaaccc gcccctcggg tggcccggcg
11941 tcggggctca cactgccgcc tagtggcagc cgaacacgcc cttgccccat ccctcccccg
12001 catcctcccc cgtggctctt ttccttaggg atcttgccaa ggtgatgctt ggcagcccac
12061 ggtaaaggaa gggggaaaaa gattaggtgg gagagagaga gagagagaga gagagagaga
12121 gagagagaga gagagagaga gagagagaga gagagagaaa gagagagaga tgtttgagag
12181 agggcaaagt ggtttcaaat ttttccaata cattcagaag ccgagtggga aagggggctg
12241 tgtgacctaa caggacagaa ctttctccaa ttactgggtg actcagctgc actggtgact
12301 cacttcaatg tgtcatttcc ggctgctgta agtgagcagt ggacacgtgg gggggggggg
12361 gtgaggatga aagaaacagc cagctcctgg tcaaccacct tagttagata atcttttttg
12421 aaagcttcct agctgggggt atgatcagaa aaccaattta ctgaaaaact gcacaggaag
12481 gtaacgtgaa tctaatttca tagcgggccg ctctgcatcc gttacatctc cactggaaaa
12541 aaataatcat tttctttttg tgtgtgtgtg tgtgttttag cttttctccc tctccctctt
12601 tctctctcat ttcattatgc actggataac catacaccgt gacccacagg ggcccaaatg
12661 tggggtcaca tggtcttgaa ttttgtgggg tacatatgcc tttgtttgtt tgttttcact
12721 tttgatatat aaacaggtaa atgtgttttt aaaaaataat aaaaatagag aatatgcaga
12781 caaaattgct tgctttttgc cttctgtgtc tgacccaagg caagggattc gagcagtatt
12841 gcgggctggt cagatggctc agtgggcaga acacaggcct cccaagacct gagctcaaac
12901 accctggatc ccacaggatg ggaggagaga accggctcct gaaagctgtc ctctgacctc
12961 cacacacaaa acatggcaca tgctccccca cacacagacg ataataatga aataaaggta
13021 agaggcaggc aagagggctc agatggtgaa agcacttctg agaagcctaa caatgaccgt
13081 ggtttgattc ccaggaccca cacgatagaa gacaagaacc gacaggagtt gctccctgac
13141 ttgcacacat gcatgatggg cacacttatg tgtgcacgcc catacataca cacacacaca
13201 cacacacaca cacacacaca cacacacaat gtaagtaaac cggatatgct agcacgcttt
13261 taatcccagc acttgggagg cagaagcagg caagatctct gagtttgagg gtagtctggt
13321 ctacagacag cattccagga tagccagggc tacacagaga gaccccatct cagaaaaaaa
13381 caaacgaaac tgagcagtgg gcgtggtggg acacacctgt gtgctagcta gtaagtagca
13441 cttgggaggc agaggcagga ggatcaccag ttggaggtga gttgggcctc gggtctaagg
13501 tgggctccat aacaaatgaa agcagcaaca gcagatcttg ggtggtcaca ggacttgcgt
13561 gaactgcaca cccagaggtc cgaacctgtg ggggaagccg tgagtcaccg taacactgta
13621 atgtgtctcc aggacaagtg gtgcagggct tgattctctc ccagaaacca tcctaagagg
13681 gggacaggat gggttgagga cacggctcag ttggatgaag ttgcccagca ttcgggaagc
13741 tctacaatta atccttggca cttccagccg tcgggagata gaggcaaaag agttggaaat
13801 tcaagaccat ctggggccaa cacgaactac acatgacctt gactccagga aaacagcagg
13861 agggagaaga agagagagag attggggcag gaggtaggct gggtttgagg gtactcaacc
13921 ttaatcccag cacttgagaa acagaggcag atggagatct gtgagttcaa agctagcctg
13981 gtttatacag cgtgtttcag gccagctaga gagacagata gatcctggca agaaaaaaga
14041 gagagagaga gagagagaga gagagagaga gagagagaga gagagagaga tggtgggtcg
14101 tggggagaga gaaagggaag gaagagagta tggaatatgc ctgtgcctag ggagttttat
14161 accagaataa ccttcgcagg agagccaggt ttggtgctgt atacctaaaa gcccagtgtt
14221 tgtaggtaga ggcaaaaaga tcaagagttc aaactcattc tgtgctacgt agtgagttca
14281 aggtgagcct gggatatgta aa
//GenBank-Updates@genbank.bio.net (09/19/90)
LOCUS RATPAI1AA 14302 bp ds-DNA ROD 19-SEP-1990
DEFINITION Rat plasminogen activator inhibitor-1.
ACCESSION J05206
KEYWORDS plasminogen activator inhibitor-1.
SOURCE R.norvegicus (strain Buffalo) HTC hepatoma cells DNA, clones
lambda-[MZ,BL].
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 14302)
AUTHORS Bruzdzinski,C.J., Riordan,M.F., Nordby,E.C., Suter,S.M. and
Gelehrter,T.D.
TITLE Isolation and characterization of the rat plasminogen activator
inhibitor-1 gene
JOURNAL J. Biol. Chem. 265, 2078-2085 (1990)
STANDARD full staff_entry
COMMENT Draft entry and computer-readable sequence for [1] kindly submitted
by C.J.Bruzdzinski, 03-FEB-1990.
FEATURES from to/span description
pept 3586 3856 plasminogen activator inhibitor-1, exon 2
(first expressed exon)
5124 5357 plasminogen activator inhibitor-1, exon 3
6870 7064 plasminogen activator inhibitor-1, exon 4
7699 7897 plasminogen activator inhibitor-1, exon 5
9617 9717 plasminogen activator inhibitor-1, exon 6
9820 9906 plasminogen activator inhibitor-1, exon 7
10664 10747 plasminogen activator inhibitor-1, exon 8
11018 11055 plasminogen activator inhibitor-1, exon 9
pre-msg 236 11016 plasminogen activator inhibitor-1 mRNA and
introns
IVS 2536 3584 Intron 1
IVS 3857 5123 Intron 2
IVS 5358 6869 Intron 3
IVS 7065 7698 Intron 4
IVS 7898 9616 Intron 5
IVS 9718 9819 Intron 6
IVS 9907 10663 Intron 7
IVS 10748 11017 Intron 8
signal 2364 2368 TATA box
BASE COUNT 3973 a 3548 c 3617 g 3164 t
ORIGIN
1 gatccccggg tcccagaccc ctctgacttc caaggacaga agacaaggca tttggagaca
61 tagtactggg aggataagag cagagttgtg tcttcctcag agatggccaa gaacatctgc
121 ctgtccctcc cagccctaca gcctccctca gggcttccaa gcacagatga gaacagggaa
181 aaacataaac aagcaacagc tggtcctaca ggccgtggct gggcctatga gcctgagttt
241 ccagctgagg tttccctctt tcctcaacct tcccaccccc acctgactcg gttctcgggg
301 tcgccagaga aaactcgcgg gctggttgcc ctggtatctg tttactggaa attgaaaaca
361 aacaccaaac acgctgctgt gccgcccacc taagcttccc gtgattcgcc agacagctgt
421 ctccatggat actgccaagc gaacacccat cgcctataca aaagatgaca gtttgtgaat
481 ccggaggcta agagtgcccc tcctcaaccc cacccccccc cccccccccc cgccgccgca
541 ggaccacctt ggtcttttct agtccaagcc ctctctctag tcacaaaaat ctagagttac
601 aaagggtttt tgattctgtc caaccttcaa aggcacacag cctggtcctc ttaagtgctg
661 tgcaaatgtt tctctaaaga aatcgtggag ctggggcggt gtttcagttg gtggtttgtc
721 ttgtatgttg gaagtcctgg gttcgagccc ccgtacttgc ataagcccca ggtgtggtgc
781 tgtataccgg aagtctcaat aactgggagg tgaagggagg tggatcagaa tctccagggt
841 agcctcagct gtatatatat aatgaatttg aggctaacct gggctgcata cccatgagat
901 tgtccaaaaa ccacaaaaaa ctcttcagtc attcttcctc cacaggtcta agaacagaat
961 cccactatga tatatatata tatatataac atacatacta catacatact acacacatac
1021 tacacacata catactacac gcatacatac tacatgcgta catactacat gtgtgtgtgt
1081 gtgtgtgtgt gtgtgtgtgt gttctttcta tccctggccc tgtggctcca gtccagagga
1141 gaagaaacat cctctggggt ctagagagat ggctcaaccc ttgaaagcac acactgttct
1201 tgcagaggac ctaaattcta ttcccaacac ccacaacgaa tgacatgact gcctgtaact
1261 ccagctccag ggaatctgac actttccagc tttcacatgc acacacccac aagtggacac
1321 acacacacac acacacacac acacacacac acaccgcgca cgtaattaaa acgtaagaag
1381 aaagcggggc acggcggtac acacctctga tgccagcact caggaggcag aagcaggccg
1441 acctctgtga gttggaagcc agccagagct ccagcttgag ttccaggcta gccaggacta
1501 cataatgaat actctagcta aacaaacaaa aacgaatgaa caaacgaatg aaggataaaa
1561 taaaatcgta agaaaacacc tctttctgtc tcagtcatcc taggctgctc tactggtcct
1621 tgctccttga caaagctttc tgtggtaacc cctgtgctca tttgtggaaa agtctggtcc
1681 aatccagcca ccagcgcccc acccagtaca cctcaaaacc cagccacaca aggttattga
1741 cacaaagagc gagccctcag ggcaccagga gagtctggcc ccatgtgggg agtcagaggg
1801 cttcaccgaa ggcctggcgg gcacatggag ggaggaggaa aggacttgaa gttctctatt
1861 gggcttaagt ccaagaggaa ccagaactca gacaatcaca gggcacattt cgtgctctgg
1921 cactgggcag aaacccaaga gaaagccaag ccaacttttc ctggatatag gccgacggtg
1981 aacaaggggt agacagtact ggcagggtcc atagcttctc tgtgatggct gtctccaaag
2041 gacagagggt catgttgcca caggctgagg ctcaaggaag ggagtcctaa acaccaggca
2101 ctgtaggctc tgtggtaccg ccaagggtct agacgaccga ccagccaaag gcaaagggac
2161 agagatgttc cagtcaaggc aatcaggatt tgctcaatta tcccccatgc cctctcacac
2221 acgtacacac acgtgtccca gcaagttact gggagggagg gaaggagaga gggggcaggg
2281 cgggcgagca gcccagacat ttccagagtt agaaggtggg tggggctgga acatgagttc
2341 atctatttcc ggcccacatc tggtataaag ggagcctgca gccagggaca gagcacagct
2401 ggatcaggct gctgcagatc cccgagagct ttgtgaagga ggaacgctgc acacccgcct
2461 cccgcagcac acagccaacc acagctgagc gacacgcaac aagagccaat cacaaggcac
2521 ttccgaaagc tccaggtagg agaaaagctt tctctctctc tcaccttagg ctttaaatga
2581 aagtaggaaa catcccttcc cagaggtctc cgtctgtcac cctcgttttc cctcggttcc
2641 cttccactct tttctggaac tctgcagtcc gccctagccc aaccaggacc acaggtggtc
2701 gagaaagatg gtcaaactgc gtttccaacc ctgtatccca gaagcgaaca cattgtcttt
2761 cagtcactct ccagcaaacc tcccctttat caatttagca aaggggcttt acttttaaag
2821 atttatttat ttattatata taagtacact gtagctgcct tcagatacac cagaagaggg
2881 catcggatct ctttacaaga tggttgtaag ccaccatgtg gttgctggga attgaactca
2941 ggacctctgg aagagtaatc gggtgctctt aaccgctgag ccatctctcc agcccggggc
3001 tttactttta aaaagaaagt tgcatttata tgtgtatgta tgtgtgtgtg caaattcgtg
3061 tatcacacaa atattcgtgt tcaagtgtga aaatcaggaa acaactttca ggggtcagct
3121 cccattttaa gccaaaagtc gtcactgtcc aaaggtctct gagccccacg gaagggacgg
3181 gagacgcaca ggaggagttt ttctaagatt cactcaggtt aaaaaaaaat gaggacagct
3241 tatgttaaaa atcaaatagc atctatgggc agtaattcat gcctgtaatc acagcatttg
3301 ggagaagcga aacaggagtg tcctgagttc aagaccagcc ctgattatgt agcaaacaag
3361 actctcagaa aaaaattaaa agaattgtgt ggaggtagaa ggagatgagc tcattatcca
3421 attgcattat ggggtcttaa tgaatgtgaa cttaaccaga ctggactctt acaggctaga
3481 ggcaaacaca gagagcccag tccacgactg aggaagcaac atatcccctt ctggacagtc
3541 ttccagaagg atctccttat tggattctct tctatttatc ctaggatgca gatgtcttca
3601 gccctcactt gcctcaccct gggcctggtt ctggtctttg ggaaagggtt cgcttcaccc
3661 cttccagagt cccatacagc ccagcaggcc accaacttcg gagtaaaagt gtttcagcat
3721 gtggtccagg cctccaaaga ccgaaatgtg gtcttctctc cctacggcgt gtcctcggtg
3781 ctggctatgc tgcagctgac cacagcaggg aaaacccggc agcagatcca agatgctatg
3841 ggattcaata tcagtggtaa gagatgggct agagggagac aggtgagagg gagacaggcg
3901 agaaagtaaa gatgtgctca cagaccaggg tccagagaaa cagagaaggc agggaaagct
3961 gctgcaacat caccaagtct actcacgtcc agccacagcc cagagaccac ccattttctc
4021 tcccactatt gggtcagttg accttgactt gtaccagcca gcgggttcaa ctcatgtgag
4081 cctggtgctg ggatatagtt tgcctagcat gcacaaaggc ctgggctcca ttcccaaata
4141 gagtgaaact ggaaatggtg atgtagaacc gtgaccacgt tctttgggaa gtggaggcag
4201 aagggtcagg tgttcaagct catattggct agtatcgagt tcagcgccag cctagattac
4261 gtgagacctt taaaaaaaaa taagggaggg ggcaaaacaa aacacatggt ctcaactctt
4321 ataaaccttg gttttattac ctatgaatag ggaacaagaa tgtttcccac ccaggctgag
4381 taaatatgta ataggattat gaattactcg atatccattg atataagacc aacctagcta
4441 ggtacggtgg tagagcctgt aattgcgctt aagaggctaa gagaggttga ttatgaagtc
4501 aaggccagcc taggctacat agcaagctcc actccaggct gagctataga gcaagccctg
4561 tcacaaacca aatagaagag gaagccaggc agagtgtctc gtgccaggat tcccagcagt
4621 tgtgaggcct gttagaggga ttgttataat atataagggg gtgtggggaa gaagcaaact
4681 aaagtttata atttaagaac aggatattca aatgcaaaga aaagattggg agctgagact
4741 tgaaagaagc tactaaacag atacgttgag gctgactgtg gatgacacac cctaatccca
4801 gtacaggcag aggcataagg caagagattt cctgttagct tccaagacat ctaggactct
4861 atagtgactg gtgaagcagt ctggcttaca ctgtgagagt ctcctcaggg aggggtgggg
4921 agaagagaag aaggaaggaa gaggagagga aagaatggga gacagtcagg catggcagtg
4981 cacatcttta gtcccagcac tcagagcatt ggaagagcca catgtgcctg gacaggggta
5041 gggtgctcct tgggaaacct ggcccagctg gaagcccttg gctcaacacg aggctaatgg
5101 atcctgtcct gatatctctg cagagagggg cacagctcct gccctccgaa agctctccaa
5161 ggagctcatg gggtcatgga acaagaatga gatcagtact gcggacgcca tctttgtcca
5221 gcgggaccta gagctggtcc agggcttcat gccccacttc ttcaagctct tccggaccac
5281 ggtgaagcag gtggacttct cagaggtgga aagagccaga ttcatcatca acgactgggt
5341 ggagaggcac accaaaggta ggcctcaagg aaagcaggcc catcccaagg gaagggagca
5401 gaggagggga acttggtgtc aaattcacat atctccggct ctcccttaca gctttgtctt
5461 tggggataaa agacaaatgc ctcagaaaac aaagcaaaat ggctaatgtt tgtgctatgg
5521 tgctgaggat gctcagagcc agggcctcat gcatgctggg taatctacac taccactgag
5581 ccacgccccc agtccctccc tggaggattc taggcaggtg ccactaccac tgagcctcgc
5641 ccccagtccc ctccctggag gattctaggc agggactcta ccactgagcc acgcccccca
5701 gcccctccct ggggattcta ggtccaggga ctctaccact gagctgtaac ccaaaactgt
5761 gtttatcttg gtaaggcttt gttataagca cacagtgctg ggtgtaatgg gtcatatctt
5821 gcaggacagt tcatgaagtt tggggttagc ccgaactaca taagcaagat actgctaccc
5881 tcccccccca cacacccctg caaaagaaaa cgtaaaagag cacagggaca aaaccaacca
5941 actaaagaca gttgcagtac ataagctgcc ccacaaacca aacaaacaat acaaaaccta
6001 gacccaaacc caccaggacc agtcgaggtg gctccatggg tacgtgctct tcctgtagag
6061 ctggtgatct gaatttgatt cctgaagcca cagaaatgtg aaggagagaa tcagttccac
6121 ataagttgcc ctctgacctc ccgcttgcgt gctcgccccc acccacggac tttatacctc
6181 ccgcccaccc cccacaatag taataacctt taaaataaat aagcaaaacc aaaatcaaca
6241 tgaaaggcat caaaaaaaat gaaaggcatc actgacaata agaacgtcag taactgtatt
6301 ggggggttgg ggttgggggg gacaaaagga aaagaagaga caagggaagt cggagcttct
6361 cttttttttt tttttttttt tttttttttt ggttcttttt ttttccggag ctggggaccg
6421 aactcagggc ctaggcaagc actctaccac tgagctaaat ccccaacccc aagacggagc
6481 tttctaattc tgatactaaa atggatccca gagccaagga aaacgtgctg aagccagggc
6541 tgtggctcag gcctatcatc ccagctctta gaaagctgag gcaggaggat tatcatgaac
6601 tcaaggccac cctaggctgc aaagtgaaca ttggactagg ctggactata aaaggggggt
6661 taggggggta gaagggaggg aaggagggga atagggagta agagggagaa aaggagggag
6721 ggctgaaagg catccctttt gttctactta agcatcacag ttctttgtgt cccttcacca
6781 tacatccatt taagagctgg gaacggaagg gaaaatatct cagatgctta aaacccattg
6841 cgcttcttga tcgccttgct tttccttagg tatgatcagt gacttactgg ccaagggggc
6901 tgtaaatgag ctgacacgcc tggtgctggt gaacgccctc tatttcaacg gccaatggaa
6961 gacccccttc ttagaggcca gcacccacca gcgcctgttc cacaagtctg atggtagcac
7021 catctccgtg cccatgatgg ctcagaacaa caagttcaac tacagtgagt ccaagatccc
7081 cagaccccac ctctcacaac tacagaccca gggcacgagg gagggaggac ggcagcagag
7141 gaggtggaca cacccaagtt attacaaaga cgtaccaagc aggagatact gagatagttc
7201 aagtagggga gaggggagga cagtttcttc ttgaattaga tagtctgcca gaccacatcg
7261 gctcaacaga cccttgagcc tgtctcttct cttaaggtct ctctagtgtg attatctagg
7321 gccaaggagc cagctagggt aaggctgtgc aggagttggg tgagcatgag aacgagttag
7381 tggctggagt cagacagaaa taatgaagat caagagggag aaagtaggca ggaagggtgg
7441 ggatgtggct taaggagaac gctcaccagt cttagtgaag ccctggggtc catgctcagc
7501 tcataaacca gttacggtgg ataagtcctc ggtcgtctac attgctagtt cagaaaagag
7561 aggagaagag agcctttgaa cgggatgtag agcctgacct tctagaagga gagaagggga
7621 gagaagcagg gaaagctggg aagacagcca catgagtcag agccgactcc aagcgccgcc
7681 atcttggtat ctccccagct gagttcacca ctccggatgg gcacgagtac gacatcctgg
7741 aactgcccta ccacggcgaa accctcagca tgttcattgc agcacccttt gaaaaagatg
7801 tgcccctctc cgccatcacc aacattttgg acgctgagct catcagacaa tggaagagca
7861 acatgaccag gctgccccgc ctcctcatcc tgcctaagta agccgtccca ttcgccaacg
7921 ccctaatccc gacacccacc acccctccta aagccactgt ccccttggga gtttcccaga
7981 tgggtaatgc ccacagggaa gggacatgcg tgggaggctg atgggaaacc tcctagcctg
8041 gctttgatta tggtttctaa tttcatcatc cttgtgcctg tttctactgt tggagaaaca
8101 cgtcccacat agaccatgca cagaatactc agtaagaatc aaccaaagta gaggggagtg
8161 gcacaagcct ctaaccccag tatcagactg caagattgct gaagatgtag cttagttagt
8221 tcatgcatgc tgggctagcg ttcaaatgca atactacata ggccagtcat ggtggtacaa
8281 actcgtaatc ctagcccaag aggataatga gttcaaggcc aacctgggtt agatacagca
8341 agaccctatc tcataaggga tagggggctg tcagggaaag agctggagtt gtcggggttc
8401 ttcctcacgc gcacagagcc ctaatccccc agcaccacgt gaaccagtaa tgatggtaca
8461 cagctacaat ccctaatctc atcactaggg gcggacggag ttcaaggatc atccttgttc
8521 tactggatca cgcaagaccc atcttaaaag tcagccgaag aggagctaga ggaggaaggg
8581 ggcctctgaa tcgttctaca ctcatttgta aatgtctcca atctcaaccg cccagccccc
8641 tccttccccc acccacaaac aatgaaaggc atcaattccc agagggcaga ggagacttcc
8701 aaaaacaaat ttttcttttc ttttttctct ttcccctaat ccttctgcag aatcaaaagg
8761 ggtggagagg gctgtggtcg ggtaattcca gaattacagg gaagctcccg gcccagactt
8821 cccccgtaaa ctccaagata gcaaaaatgc caggcttgga gacagaggag aattgagttg
8881 ctttagagac tagaccttct gctactgtct ttctctctca tcaagatgaa gataatgagt
8941 catgccctgg tgggaagcag aggggggccc cccaaagtct cattctcgtg cgctcaaaag
9001 cagcctgcag accacagtta gctcctacac cctcgagagg gagaatgtga acctgtcccc
9061 tcctgcagtc aaacggaata caattatgtt aaaactactg tcatatttga ggaaagccat
9121 tagtcacgga ttcgaggggg cggaaagatt gaacaatgtt cattaatatt agaagtttct
9181 ggcaaggagg aaaaataggc cagacctcct agccaaatga agtttcaaag acttctaatg
9241 ccgtactagg gggtggaggt aggaggatca gaagttcaag gtcagggctg gggtgggtat
9301 aattgagctg tgtagagtgc ttgcctgatt tgttcaaagc cccgggttca accccagggc
9361 tatataaacc agcacggtgg catacacctg taaattctag cactcaggac atagaggcag
9421 gaggatcaaa atcatctttg gatgcattaa ggaatttggg gctagcctgg gctacatgag
9481 attcagtgtc aagacaaaac aaaaaggcag acctctttcc ttcatgctca tgtccatgtc
9541 ctagagagat ccgaaggtcc tgggagaagc agcatgtgag agccaaacta acactgtccc
9601 ctgttcctgc ccataggttc tctctggaga ctgaagtgga cctcagaggg cccctggaga
9661 agctgggcat gactgacatc ttcagctcaa cccaggccga cttcacaagt ctttccggtg
9721 agaggcgatc cccctcattt tcttgattcc atgagtcaag gtttccctca gaggatagag
9781 tggaggctaa tctgtccttt gggtcccgct ctatttcaga ccaagagcag ctctctgtag
9841 cacaagcact acaaaaggtc aagatcgagg tgaacgagag cggcacagtg gcgtcttcct
9901 ccacaggtga gtgtggctct gcccgtgtcc gcccacctcc tgggatgaca gtcactacca
9961 ccacccccaa cccccacagg aaagctagtg ccagcccagt ctgcaccctt tcccaaaccc
10021 atttctcagt ggaaaatgga tccacttgcc ctgcaactct gctccctcat ctatggctct
10081 tgagatccca gtatatgatg aggaccccca aagaaagccc gaggtgttgt cacagtggga
10141 gtgaacttaa aggatgtgct tagcggtgag ccctaaatat gtttatgact gatggaaaac
10201 tggggctcag aggaagtctc aaaactttag agccaatgtc caggaacaaa gaaagcctga
10261 agccaagcac agtggtacat cctcaggaag ctgaggcaga aggatgcagg ttcaaaaacg
10321 cagggtcctg aaaaccaagg acagggagat atgagaggct gggggcgtgg cttagtggta
10381 gagcccctac ctagaatccc ccagtgaggg gctggggcat ggctcagtgg tagagcccct
10441 gcctagaatc ccccagtgat gggctagggg ggggctcagc cataatactc ttgctctagc
10501 atgccggaag ctctgggttc cattccccac tactagtttc ttttaagcca cctgaaagtc
10561 atctcgcaat gctgctgtct gatagactgg tgtcactaga tctcctggga tcactccagt
10621 gataatatcc cccaaccata acatattgtc tcttttcttt cagccattct agtctcagcc
10681 cgcatggccc ccacggagat ggttttagac cgatcctttc tctttgtggt tcggcacaat
10741 ccaacaggtg agcagaaccc tatagcattc tcctgtcctc aaggctgtac taggaaaatt
10801 attatatacc tgcccaccat gtagacatcc cccaagcccc tagggactct gcaaaggttc
10861 agaaactcag ctccgttcct tcctgagcac tctgtcacag cccacgcagg tccaggaccc
10921 cagtcctaac ttagtcaccg gggaagctgt gacccctggc aactcactca cctccttaga
10981 gctcagttct caactgtcat gcttcttctg tcctcagaga caatcctctt catgggccag
11041 ctgatggagc cttgagagtg ggatgagaag ctcttccttt gggacaaaac tggacgtgtt
11101 ataagcagag actctgaaga aaagaattgt tttaaggact ctttggggag aaagagaagg
11161 cctttctttc ttaccccggc actggtaaat ctttccaacc agcctcccag acctcagact
11221 ctcgaagagg aaagagtcta actccctcac tagggaccta tcttactaag gtctcatcca
11281 accatagaac tcacagaatc tggatctgcc cagcattcag cctttggacc cagttcccac
11341 caaggcccca gcagggccaa cccactacgc cttcactcag caaagtcttt tgtgttccag
11401 tcacactctg ggtacctctt gtatcgtcct ccattgctat gaaggatgac ccaggccaaa
11461 ggaagaagca ctgtcctatc tcaaggtcca ctgtggaaat gaacaccttg cccatcccca
11521 aggggcagca gatagacaga tcgaatgatc gcccgatatc aagccttctc ccagctcccg
11581 tcctgccctc ccttccctga ccaggcgctt gtgttatttc agagtgtaga tgacttgttt
11641 acagcttttt tcgacccaca aacttttctc attttgaaag cgtgaaagaa aggtcagatg
11701 tgcacgtgcc ttgctcttta tcctgggtct ccctgtgagg ggagaggggt cctggggaga
11761 ttccaggggt gtgattgaat atttatcttg tttatcttat acgtttgttg gggagaagaa
11821 gcactattaa ggagaaagcc ttttatttaa accatggcat atggtgtccc atttggggtc
11881 tgtatccctg tatgtcaggg aggcatcact ccacaaaccc gcccctcggg tggcccggcg
11941 tcggggctca cactgccgcc tagtggcagc cgaacacgcc cttgccccat ccctcccccg
12001 catcctcccc cgtggctctt ttccttaggg atcttgccaa ggtgatgctt ggcagcccac
12061 ggtaaaggaa gggggaaaaa gattaggtgg gagagagaga gagagagaga gagagagaga
12121 gagagagaga gagagagaga gagagagaga gagagagaaa gagagagaga tgtttgagag
12181 agggcaaagt ggtttcaaat ttttccaata cattcagaag ccgagtggga aagggggctg
12241 tgtgacctaa caggacagaa ctttctccaa ttactgggtg actcagctgc actggtgact
12301 cacttcaatg tgtcatttcc ggctgctgta agtgagcagt ggacacgtgg gggggggggg
12361 gtgaggatga aagaaacagc cagctcctgg tcaaccacct tagttagata atcttttttg
12421 aaagcttcct agctgggggt atgatcagaa aaccaattta ctgaaaaact gcacaggaag
12481 gtaacgtgaa tctaatttca tagcgggccg ctctgcatcc gttacatctc cactggaaaa
12541 aaataatcat tttctttttg tgtgtgtgtg tgtgttttag cttttctccc tctccctctt
12601 tctctctcat ttcattatgc actggataac catacaccgt gacccacagg ggcccaaatg
12661 tggggtcaca tggtcttgaa ttttgtgggg tacatatgcc tttgtttgtt tgttttcact
12721 tttgatatat aaacaggtaa atgtgttttt aaaaaataat aaaaatagag aatatgcaga
12781 caaaattgct tgctttttgc cttctgtgtc tgacccaagg caagggattc gagcagtatt
12841 gcgggctggt cagatggctc agtgggcaga acacaggcct cccaagacct gagctcaaac
12901 accctggatc ccacaggatg ggaggagaga accggctcct gaaagctgtc ctctgacctc
12961 cacacacaaa acatggcaca tgctccccca cacacagacg ataataatga aataaaggta
13021 agaggcaggc aagagggctc agatggtgaa agcacttctg agaagcctaa caatgaccgt
13081 ggtttgattc ccaggaccca cacgatagaa gacaagaacc gacaggagtt gctccctgac
13141 ttgcacacat gcatgatggg cacacttatg tgtgcacgcc catacataca cacacacaca
13201 cacacacaca cacacacaca cacacacaat gtaagtaaac cggatatgct agcacgcttt
13261 taatcccagc acttgggagg cagaagcagg caagatctct gagtttgagg gtagtctggt
13321 ctacagacag cattccagga tagccagggc tacacagaga gaccccatct cagaaaaaaa
13381 caaacgaaac tgagcagtgg gcgtggtggg acacacctgt gtgctagcta gtaagtagca
13441 cttgggaggc agaggcagga ggatcaccag ttggaggtga gttgggcctc gggtctaagg
13501 tgggctccat aacaaatgaa agcagcaaca gcagatcttg ggtggtcaca ggacttgcgt
13561 gaactgcaca cccagaggtc cgaacctgtg ggggaagccg tgagtcaccg taacactgta
13621 atgtgtctcc aggacaagtg gtgcagggct tgattctctc ccagaaacca tcctaagagg
13681 gggacaggat gggttgagga cacggctcag ttggatgaag ttgcccagca ttcgggaagc
13741 tctacaatta atccttggca cttccagccg tcgggagata gaggcaaaag agttggaaat
13801 tcaagaccat ctggggccaa cacgaactac acatgacctt gactccagga aaacagcagg
13861 agggagaaga agagagagag attggggcag gaggtaggct gggtttgagg gtactcaacc
13921 ttaatcccag cacttgagaa acagaggcag atggagatct gtgagttcaa agctagcctg
13981 gtttatacag cgtgtttcag gccagctaga gagacagata gatcctggca agaaaaaaga
14041 gagagagaga gagagagaga gagagagaga gagagagaga gagagagaga tggtgggtcg
14101 tggggagaga gaaagggaag gaagagagta tggaatatgc ctgtgcctag ggagttttat
14161 accagaataa ccttcgcagg agagccaggt ttggtgctgt atacctaaaa gcccagtgtt
14221 tgtaggtaga ggcaaaaaga tcaagagttc aaactcattc tgtgctacgt agtgagttca
14281 aggtgagcct gggatatgta aa
//