GenBank-Updates@genbank.bio.net (09/20/90)
LOCUS BOVPAS 3589 bp ss-mRNA MAM 20-SEP-1990
DEFINITION Bovine poly(ADP-ribose) synthetase mRNA, complete cds.
ACCESSION D90073
KEYWORDS DNA binding protein; poly(ADP-ribose) synthetase;
zinc finger protein.
SOURCE Bovine thymus, cDNA to mRNA, clone pSO-7.
ORGANISM Bos taurus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Artiodactyla; Ruminantia; Pecora; Bovidae.
REFERENCE 1 (bases 1 to 3589)
AUTHORS Saito,I., Hatakeyama,K., Kido,T., Ohkubo,H., Nakanishi,S. and
Ueda,K.
TITLE Cloning of a full-length cDNA encoding bovine thymus
poly(ADP-ribose) synthetase: Evolutionally conserved segments and
their potential functions
JOURNAL Gene 90, 249-254 (1990)
STANDARD full staff_entry
COMMENT These data kindly submitted in computer readable form by: Isao
Saito Department of Clinical Science and Laboratory Medicine
Faculty of Medicine, Kyoto University Shogoinkawahara-cho 54,
Sakyo-ku Kyoto 606 Japan Phone: 075-751-3467 Fax: 075-771-4792
Zinc-binding finger motifs are observed in seq. 21-51 and 128-165.
The sequences, 200-220 and 250-270, showed helix-turn-helix
structure. Nucleotide-binding fold was found in seq. 890-903.
FEATURES from to/span description
pept 77 3127 poly(ADP-ribose) synthetase (EC 2.4.2.30)
signal 224 231 nuclear location signal
BASE COUNT 975 a 879 c 1010 g 725 t
ORIGIN
1 tggatgagac ggcactagca gcagcgggtc tccaggtcgc ggcgtcgggc ttccggagct
61 gtgagcggtt agaaggatgg cggagtcttc agacaagctc taccgggtcg agtacgccaa
121 gagcgggcgc gcgtcttgca agaaatgcaa agagagcatc cccaaggact cgatccggat
181 ggccttcatg gtggagtcgc ccatgttcga tgggaaaatc ccgcactggt accacctctc
241 ctgcttctgg aaggtcggct tctccatctg gcaccctgat gtcgaggtgg aggggttctc
301 tgagctccgc tgggatgacc agcagacgat caagaagatg gccgagactg gcggacggac
361 agatgtttca ggcaaaggcc aagatggagt tggcagcaag accgagaaga cgttgattga
421 cttcggggca gggtacgcca agtccaacag aagcacgtgc aagagctgca tggagaagat
481 agacaagggc caggtgcgcc tgtctaagaa ggtggtgtac cccgataagc cccagctggg
541 catggttgac tgctggtacc acccaaagtg ttttgttcag aaacgggagg agctgggctt
601 ccgtcccgag ttcagcgcaa cgcacctcat gggcttcagc gtcctcaccg cagaggacca
661 agaaaccctc aagaagcaac tcccggccat caagggtgaa agaaagagaa aaggtgatga
721 ggtggatgga atagatgaag tgaccaagaa gaagtctaaa aaagaaaaag acaaggagat
781 taaacttgaa aaggccctta aggcccagaa cgacctgatc tggaatgtca aggacgagct
841 aaagaaagcg tgctctacga acgacctgaa agagttgctc atcttcaaca agcaggaagt
901 gccttccggg gagtcggcga tcttggaccg cgtggccgac ggtatggtgt ttggcgccct
961 ccttccctgc gaggaatgct cgggccagct ggtcttcaag ggcgacgcct attactgtac
1021 cggggatgtg actgcctgga ccaagtgtat ggtcaagaca cagacgccca accggaagga
1081 gtgggtgacc ccaaaggaat tccgagaaat ctcttacttc aagaaactga agatcaaaaa
1141 gcaggaccgt atattccccc cagagagcag caccccagtg ggggcagcag ccccaccctc
1201 cgcagcttca gcgcctgccg ctgtgcactc tggcccccca gacaagccat tatccaacat
1261 gaagatcctg actctcggga aactctccca gaacaaggat gaagtgaagg ccacgattga
1321 gaaactcggg gggaaattga cagggacggc caacaaggcc tccctgtgta tcagcaccaa
1381 aaaggaggtg gacaagttga ataaaaagat ggaggaagta aaagaagcca acatccgtgt
1441 cgtgtctgag gacttcctcc aagacatctc cgcctccacc aagagccttc aggagttgct
1501 ctccacccac ctcttgtccc cctggggagc cgaggtgaag gtggagcctg ttgaagcagt
1561 gggcccaaag gggaagtcgg gggccgcgcc ctccaagaag agcaagggtc ccgtcaagga
1621 ggaaggtacc aacaaatctg aaaagaggat gaaattaact cttaaaggag gagcagctgt
1681 cgaccctgat tcaggtctgg aacacaatgc acacgtcctc gagaaaggcg ggaaggtctt
1741 cagcgccacc ctcgggctcg tggacatcgt caaagggacc aactcctatt acaagctgca
1801 gctcctggag gatgacaaag agagcaggta ctggatattc aggtcctggg gccgtgtggg
1861 cacggtgatt ggtagtaaca aactggagca gatgccatcc aaggaggatg ccattgagca
1921 ttttatgaaa ttatatgaag agaaaaccgg aaacgcctgg cactctaaaa actttacgaa
1981 gcatcccaaa aagttctacc ctctggagat tgactacggc caggatgaag aggcggtgaa
2041 gaagttgaca gtaaaccctg gcaccaagtc caagctcccc aagccagtgc agaacctcat
2101 taagatgatc tttgatgtag agagtatgaa gaaagccatg gtggagtatg agattgacct
2161 tcagaagatg cccttgggga agctgagcaa aaggcagatc caggctgcat actccatcct
2221 cagtgaggtc cagcaggcac tgtcccaggg cagcagtgac tctcacatcc tggatctctc
2281 caaccgcttc tacaccctga tcccccacga cttcgggatg aagaagcccc cgctgctgaa
2341 caacgcaaac agcgtgcagg ccaaggtgga aatgctagac aacctgctgg atattgaggt
2401 ggcctacagt ctacttaggg gtggttctga tgacagcagc aaggacccca ttgatgtcaa
2461 ctatgagaag ctcaaaactg acattaaggt tgtggacaaa gattccgaag aagccgagat
2521 cattaggaag tatgtgaaga acactcacgc gaccacacac aacgcgtacg acttagaagt
2581 cgtcgacatc ttcaagatag agcgcgaagg ggaaagccag cgttacaagc cgtttaagca
2641 gctgcataac cggaggctgc tgtggcacgg gtccaggacc accaacttcg cgggcatcct
2701 gtcccagggt ctccggatag ccccacctga agcacctgtg acgggctaca tgtttggtaa
2761 gggaatctat ttcgcggaca tggtctccaa gagtgccaac tactgccaca cgtcccaggg
2821 agacccaata ggcttgatcc tgttgggaga agctgccctt ggaaacatgt atgaattgaa
2881 acatgctcga catatcagca agttacccaa gggcaagcac agtgtcaaag gtttaggcaa
2941 aactacccct gacccatcgg ctagtattac tgtggatggt gtggaggtgc ctctcgggac
3001 agggatttca tctggtgtta atgacacctg tctgttgtat aacgagtaca tcgtctacga
3061 cattgctcag gtccacctga agtacctgct gaagctgaag ttcaacttta agacatccct
3121 gtggtgagct gtgaggtgcg caggctggtg actggcgtgc tttgcatgac tggccaggca
3181 gaaacctcag ctgagttgtc gaggcatagc tagcttcact cagtctcctt agaagggatt
3241 ttatatgaac acttggtcac atgtttcaga gcgattttcc cagcttttca aatcccttga
3301 ttgtgttggg cgggggagcg ggcggggggt ggtttcgggg tttttctcct gccagccata
3361 accctggtag gtgcaactga caatagagga gaagctgggg agggtcttac ctgtgtctag
3421 attagtccaa tgaaagagcc tcgcaggcca cattagaaca tctgccttac tggtttcccc
3481 agggaaggaa aaaaataatc ttctaccctt gtttttaagt attcatcttt agttttggaa
3541 aaatgttaag tgtttatttt gaggtcaaaa taaaaactaa tttcatact
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