GenBank-Updates@genbank.bio.net (09/21/90)
LOCUS HUMARA01 1810 bp ds-DNA PRI 21-SEP-1990
DEFINITION Human androgen receptor gene, exon 1.
ACCESSION M35844
KEYWORDS androgen receptor.
SEGMENT 1 of 8
SOURCE Human prostate DNA and, cDNA to mRNA, clones A1 and J8.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1769)
AUTHORS Tilley,W.D., Marcelli,M., Wilson,J.D. and McPhaul,M.J.
TITLE Characterization and expression of a cDNA encoding the human
androgen receptor
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 86, 327-331 (1989)
STANDARD full staff_review
REFERENCE 2 (bases 1770 to 1810)
AUTHORS Marcelli,M., Tilley,W.D., Wilson,C.M., Griffin,J.E.,
Wilson,J.D. and McPhaul,M.J.
TITLE Definition of the human androgen receptor gene structure permits
the identification of mutations that cause androgenic resistance:
Premature termination of the receptor protein at amino acid residue
588 causes complete androgen resistance
JOURNAL Mol. Endocrinol. 4, 1105-1116 (1990)
STANDARD full staff_entry
COMMENT Draft entry and computer-readable sequence [1] kindly submitted by
M.J. McPhaul, 09-DEC-1988.
FEATURES from to/span description
pept 163 + 1769 androgen receptor, exon 1 /nomgen="AR"
/map="Xcen-q13" /hgml_locus_uid="LL0058U"
IVS 1770 > 1810 androgen receptor intron A
BASE COUNT 353 a 565 c 585 g 307 t
ORIGIN
1 tttttgcgtg gttgctcccg aagtttcctt ctctggagct tcccgcacgt gggcagctag
61 ctgcagcgac taccgcatca tcacagcctg ttgaactctt ctgagcaaga gaaggggagg
121 cggggtaagg gaagtaggtg gaagattcag ccaagctcaa ggatggaagt gcagttaggg
181 ctgggaaggg tctaccctcg gccgccgtcc aagacctacc gaggagcttt ccagaatctg
241 ttccagagcg tgcgcgaagt gatccagaac ccgggcccca ggcacccaga ggccgcgagc
301 gcagcacctc ccggcgccag tttgctgctg ctgcagcagc agcagcagca gcagcagcag
361 cagcagcagc agcagcagca gcagcagcag caagagacta gccccaggca gcagcagcag
421 cagcagggtg aggatggttc tccccaagcc catcgtagag gccccacagg ctacctggtc
481 ctggatgagg aacagcaacc ttcacagccg cagtcggccc tggagtgcca ccccgagaga
541 ggttgcgtcc cagagcctgg agccgccgtg gccgccagca aggggctgcc gcagcagctg
601 ccagcacctc cggacgagga tgactcagct gccccatcca cgttgtccct gctgggcccc
661 actttccccg gcttaagcag ctgctccgct gaccttaaag acatcctgag cgaggccagc
721 accatgcaac tccttcagca acagcagcag gaagcagtat ccgaaggcag cagcagcggg
781 agagcgaggg agcgctcggg ggctcccact tcctccaagg acaattactt agggggcact
841 tcgaccattt ctgacaacgc caaggagttg tgtaaggcag tgtcggtgtc catgggcctg
901 ggtgtggagg cgttggagca tctgagtcca ggggaacagc ttcgggggga ttgcatgtac
961 gccccacttt tgggagttcc acccgctgtg cgtcccactc cttgtgcccc attggccgaa
1021 tgcaaaggtt ctctgctaga cgacagcgca ggcaagagca ctgaagatac tgctgagtat
1081 tcccctttca agggaggtta caccaaaggg ctagaaggcg agagcctagg ctgctctggc
1141 agcgctgcag cagggagctc cgggacactt gaactgccgt ctaccctgtc tctctacaag
1201 tccggagcac tggacgaggc agctgcgtac cagagtcgcg actactacaa ctttccactg
1261 gctctggccg gaccgccgcc ccctccgccg cctccccatc cccacgctcg catcaagctg
1321 gagaacccgc tggactacgg cagcgcctgg gcggctgcgg cggcgcagtg ccgctatggg
1381 gacctggcga gcctgcatgg cgcgggtgca gcgggacccg gttctgggtc accctcagcc
1441 gccgcttcct catcctggca cactctcttc acagccgaag aaggccagtt gtatggaccg
1501 tgtggtggtg gtgggggtgg tggcggcggc ggcggcggcg gcggcggcgg cggcggcggc
1561 ggcggcggcg gcgaggcggg agctgtagcc ccctacggct acactcggcc ccctcagggg
1621 ctggcgggcc aggaaagcga cttcaccgca cctgatgtgt ggtaccctgg cggcatggtg
1681 agcagagtgc cctatcccag tcccacttgt gtcaaaagcg aaatgggccc ctggatggat
1741 agctactccg gaccttacgg ggacatgcgg taagtttttc cttccagaaa tgtcgctttc
1801 ggcccaggga
//