GenBank-Updates@genbank.bio.net (09/21/90)
LOCUS HUMARA02 269 bp ds-DNA PRI 21-SEP-1990
DEFINITION Human androgen receptor gene, exon 2.
ACCESSION M35845
KEYWORDS androgen receptor.
SEGMENT 2 of 8
SOURCE Human prostate DNA and, cDNA to mRNA, clones A1 and J8.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 45 to 196)
AUTHORS Tilley,W.D., Marcelli,M., Wilson,J.D. and McPhaul,M.J.
TITLE Characterization and expression of a cDNA encoding the human
androgen receptor
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 86, 327-331 (1989)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 44; 197 to 269)
AUTHORS Marcelli,M., Tilley,W.D., Wilson,C.M., Griffin,J.E.,
Wilson,J.D. and McPhaul,M.J.
TITLE Definition of the human androgen receptor gene structure permits
the identification of mutations that cause androgenic resistance:
Premature termination of the receptor protein at amino acid residue
588 causes complete androgen resistance
JOURNAL Mol. Endocrinol. 4, 1105-1116 (1990)
STANDARD full staff_entry
COMMENT Draft entry and computer-readable sequence [1] kindly submitted by
M.J. McPhaul, 09-DEC-1988.
FEATURES from to/span description
pept + 45 + 196 androgen receptor, exon 2 /nomgen="AR"
/map="Xcen-q13" /hgml_locus_uid="LL0058U"
IVS < 1 44 androgen receptor intron A
IVS 197 > 269 androgen receptor intron b
BASE COUNT 57 a 65 c 61 g 86 t
ORIGIN Chromosome Xcen-q13.
1 cattcagtga catgtgttgc attggttttt tgtgtctttt ccagtttgga gactgccagg
61 gaccatgttt tgcccattga ctattacttt ccaccccaga agacctgcct gatctgtgga
121 gatgaagctt ctgggtgtca ctatggagct ctcacatgtg gaagctgcaa ggtcttcttc
181 aaaagagccg ctgaaggtaa agggtcttgc acatgcagct tctctttccc tttctcgttt
241 accttccaga gagagacact aacctttca
//