GenBank-Updates@genbank.bio.net (09/21/90)
LOCUS HUMARA02 269 bp ds-DNA PRI 21-SEP-1990 DEFINITION Human androgen receptor gene, exon 2. ACCESSION M35845 KEYWORDS androgen receptor. SEGMENT 2 of 8 SOURCE Human prostate DNA and, cDNA to mRNA, clones A1 and J8. ORGANISM Homo sapiens Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae. REFERENCE 1 (bases 45 to 196) AUTHORS Tilley,W.D., Marcelli,M., Wilson,J.D. and McPhaul,M.J. TITLE Characterization and expression of a cDNA encoding the human androgen receptor JOURNAL Proc. Natl. Acad. Sci. U.S.A. 86, 327-331 (1989) STANDARD full staff_review REFERENCE 2 (bases 1 to 44; 197 to 269) AUTHORS Marcelli,M., Tilley,W.D., Wilson,C.M., Griffin,J.E., Wilson,J.D. and McPhaul,M.J. TITLE Definition of the human androgen receptor gene structure permits the identification of mutations that cause androgenic resistance: Premature termination of the receptor protein at amino acid residue 588 causes complete androgen resistance JOURNAL Mol. Endocrinol. 4, 1105-1116 (1990) STANDARD full staff_entry COMMENT Draft entry and computer-readable sequence [1] kindly submitted by M.J. McPhaul, 09-DEC-1988. FEATURES from to/span description pept + 45 + 196 androgen receptor, exon 2 /nomgen="AR" /map="Xcen-q13" /hgml_locus_uid="LL0058U" IVS < 1 44 androgen receptor intron A IVS 197 > 269 androgen receptor intron b BASE COUNT 57 a 65 c 61 g 86 t ORIGIN Chromosome Xcen-q13. 1 cattcagtga catgtgttgc attggttttt tgtgtctttt ccagtttgga gactgccagg 61 gaccatgttt tgcccattga ctattacttt ccaccccaga agacctgcct gatctgtgga 121 gatgaagctt ctgggtgtca ctatggagct ctcacatgtg gaagctgcaa ggtcttcttc 181 aaaagagccg ctgaaggtaa agggtcttgc acatgcagct tctctttccc tttctcgttt 241 accttccaga gagagacact aacctttca //