GenBank-Updates@genbank.bio.net (09/21/90)
LOCUS HUMARA04 378 bp ds-DNA PRI 21-SEP-1990
DEFINITION Human androgen receptor gene, exon 4.
ACCESSION M35847
KEYWORDS androgen receptor.
SEGMENT 4 of 8
SOURCE Human prostate DNA and, cDNA to mRNA, clones A1 and J8.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 41 to 328)
AUTHORS Tilley,W.D., Marcelli,M., Wilson,J.D. and McPhaul,M.J.
TITLE Characterization and expression of a cDNA encoding the human
androgen receptor
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 86, 327-331 (1989)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 40; 329 to 378)
AUTHORS Marcelli,M., Tilley,W.D., Wilson,C.M., Griffin,J.E.,
Wilson,J.D. and McPhaul,M.J.
TITLE Definition of the human androgen receptor gene structure permits
the identification of mutations that cause androgenic resistance:
Premature termination of the receptor protein at amino acid residue
588 causes complete androgen resistance
JOURNAL Mol. Endocrinol. 4, 1105-1116 (1990)
STANDARD full staff_entry
COMMENT Draft entry and computer-readable sequence [1] kindly submitted by
M.J. McPhaul, 09-DEC-1988.
FEATURES from to/span description
pept + 41 + 328 androgen receptor, exon 4 /nomgen="AR"
/map="Xcen-q13" /hgml_locus_uid="LL0058U"
IVS < 1 40 androgen receptor intron C
IVS 329 > 378 androgen receptor intron D
BASE COUNT 107 a 91 c 101 g 79 t
ORIGIN
1 ccactgatga taaattcaag tctctcttcc ttcccaatag cccggaagct gaagaaactt
61 ggtaatctga aactacagga ggaaggagag gcttccagca ccaccagccc cactgaggag
121 acaacccaga agctgacagt gtcacacatt gaaggctatg aatgtcagcc catctttctg
181 aatgtcctgg aagccattga gccaggtgta gtgtgtgctg gacacgacaa caaccagccc
241 gactcctttg cagccttgct ctctagcctc aatgaactgg gagagagaca gcttgtacac
301 gtggtcaagt gggccaaggc cttgcctggt aaggaaaagg gaagtgggag catgagataa
361 gggggatcat atttagtg
//