GenBank-Updates@genbank.bio.net (09/21/90)
LOCUS HUMARA05 286 bp ds-DNA PRI 21-SEP-1990
DEFINITION Human androgen receptor gene, exon 5.
ACCESSION M35848
KEYWORDS androgen receptor.
SEGMENT 5 of 8
SOURCE Human prostate DNA and, cDNA to mRNA, clones A1 and J8.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 80 to 224)
AUTHORS Tilley,W.D., Marcelli,M., Wilson,J.D. and McPhaul,M.J.
TITLE Characterization and expression of a cDNA encoding the human
androgen receptor
JOURNAL Proc. Natl. Acad. Sci. U.S.A. 86, 327-331 (1989)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 79; 225 to 286)
AUTHORS Marcelli,M., Tilley,W.D., Wilson,C.M., Griffin,J.E.,
Wilson,J.D. and McPhaul,M.J.
TITLE Definition of the human androgen receptor gene structure permits
the identification of mutations that cause androgenic resistance:
Premature termination of the receptor protein at amino acid residue
588 causes complete androgen resistance
JOURNAL Mol. Endocrinol. 4, 1105-1116 (1990)
STANDARD full staff_entry
COMMENT Draft entry and computer-readable sequence [1] kindly submitted by
M.J. McPhaul, 09-DEC-1988.
FEATURES from to/span description
pept + 80 + 224 androgen receptor, exon 5 /nomgen="AR"
/map="Xcen-q13" /hgml_locus_uid="LL0058U"
IVS < 1 79 androgen receptor intron D
IVS 225 > 286 androgen receptor intron E
BASE COUNT 59 a 87 c 69 g 71 t
ORIGIN
1 tgcccaacag ggagtcagac ttagctcaac ccgtcagtag tacccagact gaccactgcc
61 tctgcctctt cttctccagg cttccgcaac ttacacgtgg acgaccagat ggctgtcatt
121 cagtactcct ggatggggct catggtgttt gccatgggct ggcgatcctt caccaatgtc
181 aactccagga tgctctactt cgcccctgat ctggttttca atgagtaagt gctcctgggg
241 cccagagacc tcactaaaat acagcagctt ggccagacct ggttgg
//