GenBank-Updates@genbank.bio.net (09/22/90)
LOCUS HUMCSDF1 3939 bp ss-mRNA PRI 22-SEP-1990
DEFINITION Human macrophage-specific colony-stimulating factor (CSF-1) mRNA,
complete cds.
ACCESSION M37435
KEYWORDS colony stimulating factor; hematopoetic growth factor.
SOURCE Human trophoblast cell line (TPA30-1), cDNA to mRNA, clone
3ACSF-69.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3939)
AUTHORS Wong,G.G., Temple,P.A., Leary,A.C., Witek-Giannotti,J.S.,
Yang Y,-C., Ciarletta,A.B., Chung,M., Murtha,P., Kriz,R.,
Kaufman,R.J., Ferenz,C.R., Sibley,B.S., Turner,K.J., Ferenz,C.R.,
Sibley,B.S., Turner,K.J., Hewick,R.M., Clark,S.C., Yanai,N.,
Yokota,H., Yamada,M., Saito,M., Motoyoshi,K. and Takaku,F.
TITLE Human CSF-1: Molecular cloning and expression of 4-kb cDNA encoding
the human urinary protein
JOURNAL Science 235, 1504-1508 (1987)
STANDARD simple staff_entry
FEATURES from to/span description
pept 106 1770 colony-stimulating factor (CSF-1) precursor
sigp 106 201 colony-stimulating factor signal peptide
matp 202 1767 colony stimulating factor
BASE COUNT 832 a 1259 c 1059 g 789 t
ORIGIN
1 cctgggtcct ctcggcgcca gagccgctct ccgcatccca ggacagcggt gcggccctcg
61 gccggggcgc ccactccgca gcagccagcg agccagctgc cccgtatgac cgcgccgggc
121 gccgccgggc gctgccctcc cacgacatgg ctgggctccc tgctgttgtt ggtctgtctc
181 ctggcgagca ggagtatcac cgaggaggtg tcggagtact gtagccacat gattgggagt
241 ggacacctgc agtctctgca gcggctgatt gacagtcaga tggagacctc gtgccaaatt
301 acatttgagt ttgtagacca ggaacagttg aaagatccag tgtgctacct taagaaggca
361 tttctcctgg tacaagacat aatggaggac accatgcgct tcagagataa caccgccaat
421 cccatcgcca ttgtgcagct gcaggaactc tctttgaggc tgaagagctg cttcaccaag
481 gattatgaag agcatgacaa ggcctgcgtc cgaactttct atgagacacc tctccagttg
541 ctggagaagg tcaagaatgt ctttaatgaa acaaagaatc tccttgacaa ggactggaat
601 attttcagca agaactgcaa caacagcttt gctgaatgct ccagccaaga tgtggtgacc
661 aagcctgatt gcaactgcct gtaccccaaa gccatcccta gcagtgaccc ggcctctgtc
721 tcccctcatc agcccctcgc cccctccatg gcccctgtgg ctggcttgac ctgggaggac
781 tctgagggaa ctgagggcag ctccctcttg cctggtgagc agcccctgca cacagtggat
841 ccaggcagtg ccaagcagcg gccacccagg agcacctgcc agagctttga gccgccagag
901 accccagttg tcaaggacag caccatcggt ggctcaccac agcctcgccc ctctgtcggg
961 gccttcaacc ccgggatgga ggatattctt gactctgcaa tgggcactaa ttgggtccca
1021 gaagaagcct ctggagaggc cagtgagatt cccgtacccc aagggacaga gctttccccc
1081 tccaggccag gagggggcag catgcagaca gagcccgcca gacccagcaa cttcctctca
1141 gcatcttctc cactccctgc atcagcaaag ggccaacagc cggcagatgt aactgctaca
1201 gccttgccca gggtgggccc cgtgatgccc actggccagg actggaatca caccccccag
1261 aagacagacc atccatctgc cctgctcaga gaccccccgg agccaggctc tcccaggatc
1321 tcatcactgc gcccccaggc cctcagcaac ccctccaccc tctctgctca gccacagctt
1381 tccagaagcc actcctcggg cagcgtgctg ccccttgggg agctggaggg caggaggagc
1441 accagggatc ggacgagccc cgcagagcca gaagcagcac cagcaagtga aggggcagcc
1501 aggcccctgc cccgttttaa ctccgttcct ttgactgaca caggccatga gaggcagtcc
1561 gagggatcct ccagcccgca gctccaggag tctgtcttcc acctgctggt gcccagtgtc
1621 atcctggtct tgctggctgt cggaggcctc ttgttctaca ggtggaggcg gcggagccat
1681 caagagcctc agagagcgga ttctcccttg gagcaaccag agggcagccc cctgactcag
1741 gatgacagac aggtggaact gccagtgtag agggaattct aagctggacg cacagaacag
1801 tctcttcgtg ggaggagaca ttatggggcg tccaccacca cccctccctg gccatcctcc
1861 tggaatgtgg tctgccctcc accagagctc ctgcctgcca ggactggacc agagcagcca
1921 ggctggggcc cctctgtctc aacccgcaga cccttgactg aatgagagag gccagaggat
1981 gctccccatg ctgccactat ttattgtgag ccctggaggc tcccatgtgc ttgaggaagg
2041 ctggtgagcc cggctcagga ccctcttccc tcaggggctg cagcctcctc tcactccctt
2101 ccatgccgga acccaggcca gggacccacc ggcctgtggt ttgtgggaaa gcagggtgca
2161 cgctgaggag tgaaacaacc ctgcacccag agggcctgcc tggtgccaag gtatcccagc
2221 ctggacaggc atggacctgt ctccagacag aggagcctga agttcgtggg gcgggacagc
2281 ctcggcctga tttcccgtaa aggtgtgcag cctgagagac gggaagagga ggcctctgca
2341 cctgctggtc tgcactgaca gcctgaaggg tctacaccct cggctcacct aagtccctgt
2401 gctggttgcc aggcccagag gggaggccag ccctgccctc aggacctgcc tgacctgcca
2461 gtgatgccaa gagggggatc aagcactggc ctctgcccct cctccttcca gcacctgcca
2521 gagcttctcc agcaggccaa gcagaggctc ccctcatgaa ggaagccatt gcactgtgaa
2581 cactgtacct gcctgctgaa cagcctcccc ccgtccatcc atgagccagc atccgtccgt
2641 cctccactct ccagcctctc cccagcctcc tgcactgagc tggcctcacc agtcgactga
2701 gggagcccct cagccctgac cttctcctga cctggccttt gactccccgg agtggagtgg
2761 ggtgggagaa cctcctgggc cgccagccag agccgctctt taggctgtgt tcttcgccca
2821 ggtttctgca tcttccactt tgacattccc aagagggaag ggactagtgg gagagagcaa
2881 gggaggggag ggcacagaca gagagcctac agggcgagct ctgactgaag atgggccttt
2941 gaaatatagg tatgcacctg aggttggggg agggtctgca ctcccaaacc ccagcgcagt
3001 gtcctttccc tgctgccgac aggaacctgg ggctgagcag gttatccctg tcaggagccc
3061 tggactgggc tgcatctcag ccccacctgc atggtatcca gctcccatcc acttctcacc
3121 cttctttcct cctgaccttg gtcagcagtg atgacctcca actctcaccc accccctcta
3181 ccatcacctc taaccaggca agccagggtg ggagagcaat caggagagcc aggcctcagc
3241 ttccaatgcc tggagggcct ccactttgtg gccagcctgt ggtgctggct ctgaggccta
3301 ggcaacgagc gacagggctg ccagttgccc ctgggttcct ttgtgctgct gtgtgcctcc
3361 tctcctgccg ccctttgtcc tccgctaaga gaccctgccc tacctggccg ctgggccccg
3421 tgactttccc ttcctgccca ggaaagtgag ggtcggctgg ccccaccttc cctgtcctga
3481 tgccgacagc ttagggaagg gcactgaact tgcatatggg gcttagcctt ctagtcacag
3541 cctctatatt tgatgctaga aaacacatat ttttaaatgg aagaaaaata aaaaggcatt
3601 cccccttcat ccccctacct taaacatata atattttaaa ggtcaaaaaa gcaatccaac
3661 ccactgcaga agctcttttt gagcacttgg tggcatcaga gcaggaggag ccccagagcc
3721 acctctggtg tcccccaggc tacctgctca ggaacccctt ctgttctctg agaactcaac
3781 agaggacatt ggctcacgca ctgtgagatt ttgtttttat acttgcaact ggtgaattat
3841 tttttataaa gtcatttaaa tatctattta aaagatagga agctgcttat atatttaata
3901 ataaaagaag tgcacaagct gccgttgacg tagctcgag
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