GenBank-Updates@genbank.bio.net (09/22/90)
LOCUS HUMGP3A08 4610 bp ds-DNA PRI 22-SEP-1990
DEFINITION Human platelet glycoprotein IIIa, exons 4, 5 and 6.
ACCESSION M32673 J05427
KEYWORDS Alu repetitive sequence; integrin; platelet fibrinogen receptor;
platelet glycoprotein.
SEGMENT 8 of 21
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 4610)
AUTHORS Zimrin,A.B., Gidwitz,S., Lord,S., Schwartz,E., Bennett,J.S.,
White,G.C.II. and Poncz,M.
TITLE The genomic organization of platelet glycoprotein IIIa
JOURNAL J. Biol. Chem. 265, 8590-8595 (1990)
STANDARD full staff_entry
COMMENT Draft entry and computer-readable sequence for [1] kindly submitted
by M.Poncz, 07-MAR-1990.
FEATURES from to/span description
pept + 244 499 platelet glycoprotein, exon 4
2016 2178 platelet glycoprotein, exon 5
2763 + 2924 platelet glycoprotein, exon 6
IVS < 1 243 GPPIIIA intron C
IVS 500 2015 GPPIIIA intron D (no splice consensus)
IVS 2179 2762 GPPIIIA intron E
IVS 2925 > 4610 GPPIIIA intron F
rpt 3299 3569 Alu repeat
rpt 3840 3577 (c) Alu repeat
BASE COUNT 1192 a 930 c 1113 g 1230 t 145 others
ORIGIN About 210 bp after segment 7.
1 aacccgtgga actcacagta gaatccctgg tttagagaag ctggaaaatt tagatggcaa
61 agaagaggtt aaaatagagg tcaagagtta gaaggtaata gaattgcaaa ggaagaggaa
121 aagggaccag ggctttctgg tttgctttga tcatgcaatt tcttagtccc aactgtatcc
181 aaatctgctt attcaatctt ggtgggagaa gaagataaaa agtaacatct ttctgccttc
241 cagatgattc gaagaatttc tccatccaag tgcggcaggt ggaggattac cctgtggaca
301 tctactactt gatggacctg tcttactcca tgccggatga tctgtggagc atccagaacc
361 tgggtaccaa gctggccacc cagatgcgaa agctcaccag taacctgcgg attggcttcg
421 gggcatttgt ggacaagcct gtgtcaccat acatgtatat ctccccacca gaggccctcg
481 aaaacccctg ctatgagtaa gtccctcctc cagacgccag gacagcatcc tttgcccagg
541 aaggtccaag tcctggttcc tatttctagc tctaggatca ctttgttggc tgtcttcttg
601 ccaaactata gctcctttct accttggtct ccctgtttgg caatgggcta gcttgtggat
661 ctggagtgtg tgtcaatgga gctaaggtcg tttggagacc tagaaagaaa attcatcagc
721 ttctcagtct tggtaacaaa taaatagaag gcaagagaga atgggaggga aatgacgtca
781 aaagtagaaa gaaatttatg gataaggaaa ccgagaaatt acgattacag aaggatcgat
841 tccattgttg gcattattgt cttcatcaag gccggcnncc tgcagggtga aaacagaaga
901 aatgaagtgc taaggaatat aaaagagtgg aaatgacatt tgttggacac ttttatagtc
961 tgtaaatgga taacttgtgc ctctgtttga cactttggct taaaactgaa tggcttattt
1021 atttaatcgg tggagactgt gcaaatccat gtattagaat acttacaatg ctggttgctg
1081 agcctgaaaa ggtgtgaatt tacttttagt ttcaaagtta cggccaggtg gggtgactca
1141 cttctgtaat cccagcactt tgggaggcca agatgggagg atcacttgag cctaggagtt
1201 tgagttcagc ctaggcaaca tagtgagacc cccatctcta caaaaattac aaaaaaatta
1261 gctatgtgtg atggcgcatg cctgcagtcc ccaggactac agggaggctg aggtgggagg
1321 attgattgag cctgggaggt tgaggctgca gtgagccatg atttggcact gcactcactg
1381 acatgagcca ctgtctctaa aaaagaaagt ttgagtatat gatgtgcatc acctctatct
1441 gggtgtagtc ccagcagctc agctattaat taaacacact atttgactgg ggcagaaatg
1501 ctccctgtct tgcatgatct atcaatttat tgatgggttc aggaccctta acttactgat
1561 ggacgtttgc tttattgttc tttaggaaag tgttaagtat aaggtgatag taatagcaac
1621 tcgagcctcg ctctggtcta agtgctttgt gtgtatgaac ttacttaagt ctcacaactc
1681 ttatgggata tgtgctatcc tggcatnnnn nnnnnnnnnn nnnnnnnnnc caaaggtccc
1741 atgactagta cagagggcac ctgggatcta agctcaggga gtcttgtttc cagcncaatc
1801 tcttatcttc taggttagct ggatgggggt aatgttgatg gggagcttca gataatttga
1861 ggattttgga gtctgaactg tctgggtaac tgtggttgta tggaactggc cttggcatac
1921 cactatctat atttgtcccc tctctttcct tcccaattcc catgctgcct tttccatgaa
1981 ggtgtctgct taaattatct cccatccctc cccagtatga agaccacctg cttgcccatg
2041 tttggctaca aacacgtgct gacgctaact gaccaggtga cccgcttcaa tgaggaagtg
2101 aagaagcaga gtgtgtcacg gaaccgagat gccccagagg gtggctttga tgccatcatg
2161 caggctacag tctgtgatgt gagtttggag gacttggagt gccaggtgtg gctggcatag
2221 atcaaaatct gggaaaggaa gtgactgaac tctggggatt tctggtgtaa aatgagatga
2281 gaactaagca gggcttcctg cagttatgag tagtaagttg ctcctgatat tcagccttgg
2341 cttagatcca ctccctggcc tgagctgaca tttctttgaa cctcagtcgg tctcagatgt
2401 ccagggagag catctnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
2461 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
2521 nagagactca ttcagctgct tgaactaatc agctatgaga ctgttttctg aagagaatga
2581 aactcctgaa ctggaaagct tcagcttcgg ttccaaggac tgggactgag acccttgttt
2641 tgaagaaaat aagctgtcca gccctttagc cagggacgaa ccttgggtct ctgttctcta
2701 ccagtgacat ggctgaattt gttttgtctc ctctgccttt gttttttgtt ttattttaac
2761 aggaaaagat tggctggagg aatgatgcat cccacttgct ggtgtttacc actgatgcca
2821 agactcatat agcattggac ggaaggctgg caggcattgt ccagcctaat gacgggcagt
2881 gtcatgttgg tagtgacaat cattactctg cctccactac catggtgaga tctctggcac
2941 cacctatggt ttctattcat gattgtgagg gttgccctaa tctaggcaga gtctgtgtga
3001 atatgaaaat ggcagcccct ccttctgggc agggtgcagg gctcggtttc agcttgcccc
3061 tatcccttac caactggaca ccgtcatcca gcatacaacc tatataacca ttagagatgt
3121 cctgattgtg gtattatcac tgccttcact gtnnnggatc cagaatggac ccaaaggatt
3181 tttacaaccc agctggaaag caggtcttcc tctccactct gattagccct ttcttggaat
3241 accatactaa cttgtggtta ttggaagaag acagaggaaa aaaaagagaa agattggcca
3301 ggcatatgat ggctcatgcc tgtaatctca gcactttggg aggctgaggt gggaggatca
3361 cgtgagtcca ggagtttgaa accagccttc gggaaatata gtgagaccct gcctctacca
3421 agaaaatgca aaattcgttg agtgttgtgg tttgtgcctt gtgtccagct acttgtgggc
3481 tgaggcagaa agactcttag cccgtgttag gctgcagtga gctgtgatct tgccactaca
3541 ctccagcctg agtgacagag caagaaccac ccctgctttt tttttttttt tttttttttt
3601 tttttttgat acagagtctt gctttgttgc ccagctggag tgcagtagtg caatcttggc
3661 tcacaagctt caccacctca gtctcctgaa tagcttggga ccacaggcat gcactaccat
3721 gcccagctaa tttttgaaaa cagggtcttt ctatgttgcc caggctggtc tcaaactcct
3781 tggcttaagc aatctgccct cttaagcctc ccaaagtgct gggattacag gtgtgagcca
3841 ttgctcctag tggagacccc ttctcttaga aagagagaga gagagagaga gagagagaga
3901 gaggggaaag aacataaaag gcatggtgaa caggtcctac gaggaaagat taaagggcca
3961 gagtcattta gcttgaaaga aagaaggcta aggatgattt agcttataca tgagaaactt
4021 cttataagtt gttgttttat atggccatag aaggttaaac aagaggaaaa tatttaaatt
4081 gaatcaggag aaattactat aagccataag agaaatgtgc tgtaatgctc taggtatctg
4141 gggcaggtgt gaactcttcg tctcctaagg acaatatagc aacttcctca tctaggtgac
4201 ttaaaggtgt acctgtgtaa aggcaggaga ctgagctgag gatctaatga gctccctgca
4261 aggtctagga tccnnnnnnn nnncacgatt caccaccgcc cccgcacagt gtccttgagt
4321 tccttggtgt cagccatatc caagtcaagc actaccagac aatgagtcag caacatttga
4381 cccctaatct atgcaaggca ctgggccagg ggctgaggga ggtaacaaga ctatgtatgg
4441 ttctatcctt ggggagtttt tggtctactt gaggagaaag gatatatata tttacaataa
4501 cacaagatgc atgatagtgc caaatgggtg tggcacagcc aatgtggcta tacgtatcca
4561 agggaggaaa ggtcatcatg agctgggatg gccaaggagt tctcgaagaa
//