GenBank-Updates@genbank.bio.net (09/22/90)
LOCUS HUMGP3A21 6829 bp ds-DNA PRI 22-SEP-1990
DEFINITION Human platelet glycoprotein IIIa, exon 15.
ACCESSION M32686 J05427
KEYWORDS Alu repetitive sequence; integrin; platelet fibrinogen receptor;
platelet glycoprotein.
SEGMENT 21 of 21
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 6829)
AUTHORS Zimrin,A.B., Gidwitz,S., Lord,S., Schwartz,E., Bennett,J.S.,
White,G.C.II. and Poncz,M.
TITLE The genomic organization of platelet glycoprotein IIIa
JOURNAL J. Biol. Chem. 265, 8590-8595 (1990)
STANDARD full staff_entry
COMMENT Draft entry and computer-readable sequence for [1] kindly submitted
by M.Poncz, 07-MAR-1990.
FEATURES from to/span description
pept + 921 986 platelet glycoprotein, exon 15
IVS < 1 920 GPPIIIA intron N
rpt 250 7 (c) Alu repeat
rpt 386 544 Alu repeat
rpt 4055 3733 (c) Alu repeat
rpt 4388 4093 (c) Alu repeat
rpt 4891 4704 (c) Alu repeat
rpt 5178 4872 (c) Alu repeat
BASE COUNT 1788 a 1474 c 1517 g 2021 t 29 others
ORIGIN About 1121 bp after segment 20.
1 ggtggccatc atggctcaat ggcaggcctc catctcctgg gctcaagtga tcctcccacc
61 tcaccctccc aagtagccag gactacaggc acacatcacc gagccagcta atttttgtat
121 ttttttccct tgtagagaca gggtctcact ctgttaccca ggctggtcta gaactcctgg
181 gctcaagtga tcttcctacc ttggccccta aaagtgctgg gattataggc ataaaccacc
241 atgcctggcc atggttagtg cttggccagt tagatgaaaa caaattaata attatttgag
301 gcaaaagctt tcctctgtgt tctgaattcn nnnnnnnnnc cacctgatca ctcctatcac
361 tgtcacaggg aatggaaaat aggagaaggg caaaagagac nngggacaca ggggtgaaat
421 aggagaggtt ctatccccga atgctgtgga atcactgaag agtgataggc tgaatatagc
481 tccttagaaa tagtggcagg gaacaggtnn nngggctcat gcctgtaatt ccagcacttt
541 gggaggctga ggcaggtgga tcgcttgagc tcaggagttt gagaccagcc tgggcaacat
601 gaagaaaccc catctctaca aaaannnnnn nnnnccaata tgcactccag cctgggcaaa
661 caaatgagac cctgtctgaa aaaaaaaaaa aaaaaaagaa acggtggcag gatggcattc
721 tacctcatct cctcctgtta tttcctatca attcccatgc caagaactaa gtgtgagcaa
781 aatgaacatt attctgtttc attgatgatg tattccagag aacggtgcct tgggaaaact
841 tctgagatga attttaaaca ttcagggtag ggaaggactt aaggaagtca ctgtaagatg
901 ctattctgtt tcctccacag gccaacaacc cactgtataa agaggccacg tctaccttca
961 ccaatatcac gtaccggggc acttaatgat aagcagtcat cctcagatca ttatcagcct
1021 gtgccacgat tgcaggagtc cctgccatca tgtttacaga ggacagtatt tgtggggagg
1081 gatttggggc tcagagtggg gtaggttggg agaatgtcag tatgtggaag tgtgggtctg
1141 tgtgtgtgta tgtgggggtc tgtgtgttta tgtgtgtgtg ttgtgtgtgg gagtgtgtaa
1201 tttaaaattg tgatgtgtcc tgataagctg agctccttag cctttgtccc agaatgcctc
1261 ctgcagggat tcttcctgct tagcttgagg gtgactatgg agctgagcag gtgttcttca
1321 ttacctcagt gagaagccag ctttcctcat caggccattg tccctgaaga gaagggcagg
1381 gctgaggcct ctcattccag aggaagggac accaagcctt ggctctaccc tgagttcata
1441 aatttatggt tctcaggcct gactctcagc agctatggta ggaactgctg ggcttggcag
1501 cccgggtcat ctgtacctct gcctcctttc ccctccctca ggccgaagga ggagtcaggg
1561 agagctgaac tattagagct gcctgtgcct tttgccatcc cctcaaccca gctatggttc
1621 tctcgcaagg gaagtccttg caagctaatt ctttgacctg ttgggagtga ggatgtctgg
1681 gccactcagg ggtcattcat ggcctggggg atgtaccagc atctcccagt tcataatcac
1741 aacccttcag atttgcctta ttggcagctc tactctggag gtttgtttag aagaagtgtg
1801 tcacccttag gccagcacca tctctttacc tcctaattcc acaccctcac tgctgtagac
1861 atttgctatg agctggggat gtctctcatg accaaatgct tttcctcaaa gggagagagt
1921 gctattgtag agccagaggt ctggccctat gcttccggcc tcctgtccct catccatagc
1981 acctccacat acctggccct gagccttggt gtgctgtatc catccatggg gctgattgta
2041 tttaccttct acctcttggc tgccttgtga aggaattatt cccatgagtt ggctgggaat
2101 aagtgccagg atggaatgat gggtcagttg tatcagcacg tgtggcctgt tcttctatgg
2161 gttggacaac ctcattttaa ctcagtcttt aatctgagag gccacagtgc aattttattt
2221 tatttttctc atgatgaggt tttcttaact taaaagaaca tgtatataaa catgcttgca
2281 ttatatttgt aaatttatgt gtatggcaaa gaaggagagc ataggaaacc acacagactt
2341 gggcagggta cagacactcc cacttggcat cattcacagc aagtcactgg ccagtggctg
2401 gatctgtgag gggctctctc atgatagaag gctatgggga tagatgtgtg gacacattgg
2461 acctttcctg aggaagaggg actgttcttt tgtcccagaa aagcagtggc tccattggtg
2521 ttgacataca tccaacatta aaagccaccc ccaaatgccc aagaaaaaaa gaaagactta
2581 tcaacatttg ttccatgagc agaaaactgg agctctggcc tcagtgttac agctaaataa
2641 tctttaatta aggcaagtca ctttcttctt cttaaagctg ttttctagtt tgagaaatga
2701 tgggatttta gcagccagtc ttgaaggtct ctttcagtat caacattcta agatgctggg
2761 acttactgtg tcatcaaatg tgcggttaag attctctggg atattgatac tgtttgtgtt
2821 tttagttggg agatctgaga gacctggctt tggcaagagc agatgtcatt ccatatcacc
2881 tttctcaatg aaagtctcat tctatcctct ctccaaaccc gtttttccaa catttgttaa
2941 tagttacgtc tctcctgatg tagcacttaa gcttcattta gttattattt ctttcttcac
3001 tttgcacaca tttgcatcca catattaggg aagaggaatc cataagtagc tgaaatatct
3061 attctgtatt attgtgttaa cattgagaat aagccttgga attagatatg gggcaatgac
3121 tgagccctgt ctcacccatg gattactcct tactgtaggg aatggcagta tggtagaggg
3181 ataaataggg ggcggggagg gatagtcatg gatccaagaa gtccttagaa atagtggcag
3241 ggaacaggtg tggaagctca tgcctgtaat tataaccttc agctactaag acaggtgtgg
3301 tcgtcacgcc tgtaattata atcttcagtt actaagacag agtccatgag agtgttaatg
3361 ggacattttc tttagataag atgttttata tgaagaaact gtatcaaagg gggaagaaaa
3421 tgtatttaac aggtgaatca aatcaggaat cttgtctgag ctactggaat gaagttcaca
3481 ggtcttgaag accaatatta tttgtcaata tgtggggata acctgtagct gcattcatga
3541 ggtagcaaat agcagttttg gcctgtgggg tgaacagcta aacagtgttc tggcatcaga
3601 taacacggca caaagggatt gtgtctagct cttttggaga aaatttatgt ccagtctcag
3661 gatctgtgga caataacgga aaactttgaa tattcctgac aagttgccat attaggagtc
3721 agttctttac ttctctgaga ttcccaggtc atccatgatt ttttttttaa tttgagacaa
3781 agcctcactc ttgttgccca agctggaatg caatggcaag atctcagttc actgcaatct
3841 ctgcctctca ggttcaagcc attctcctgc ctcagcctcc ccagtagctg ggattacagg
3901 cacccgccac cacacccggc taatttttgt atttttagta gagacggggt ttcaccatgt
3961 tggccaggct ggtctcgaac tcctgacctt aggcgatcca ccttcctcgg cctcccacag
4021 tgctgggatt acaagtgtga agcactgtgc ccggccagtc atccatgatt ttaatggggt
4081 ccaaaggcct ctttttcttt gttaagtatt cctggttgaa atttcttttc tttttttttt
4141 tttttttgag acagagtctt gctctatcac ccaggctgga gtgcagtggc acgatctctg
4201 ctcactgcaa gcttcgcctc ccgggttcac gccattctcc tgcctcagcc tcccgagtag
4261 ctgggattac aggcacctgc caccacgccc ggctaatttc tttttgtatt tttagtagag
4321 acggggtttc acggtgttag ccaggaaggt ctcgatctcc tgacctcgtg atcctcccgc
4381 ctcggcctcc caaagtgctg ggattacagg ctggacgact gcccccggct ttggttgaaa
4441 tttcttaagt gccttcctca cttcctaacc accttctctg tttgggtttg tgcaacagta
4501 aattaaatgt actttccaaa aagaattggc ctaaggctgc tcagtgcttc ctgtgttgtt
4561 atttctgttt cctttggatg aaaagaatag gagtcattga ctcagaaatg attattttag
4621 aacaagcatg tttccaaatg taacagaatg atgactacta tgggtactga agctagcttc
4681 agaatccaga gcttctcttt agattttttt gttgttgttg ttgagatgga gtctcgctct
4741 gttgcccagg ctggagtgaa gtgagcgcga tctcggctca ttgcaacctc tgcttcctgg
4801 gctcaggaga ttctcctgcc tcagcctccc gagtggctgg gattacaggc gcccaccacc
4861 atacctggca aatttttgta tttttattta tttttgagat ggagtctctc tctgttgccc
4921 aggctggagt gcagtggtgt gatccctgct cactacaaca tctgctccgg ggctcaagca
4981 attctcctgc ctcagcctcc tgagtagctg ggattacagg tgtgcatcat cacatccggc
5041 taatttttgt atttttagta gagacagggt ttcaccatgt tggccaggct ggtcacaaac
5101 tcctgacctc aactgatccg ccggccacgg cttcccaaaa tgctggaatt acaggtgtga
5161 gccaccaggc ccggccctct ttagacttaa aattttttaa atgagtaggt tattactgtt
5221 ctaagagttt gcggtttttt tttttaattg ggtattattt aggaacttgt gcaacctcaa
5281 aagaacagac tgccagtgta gcctagattt tgtttgtagg aagcataaat ggataaaata
5341 atagcttaat ggcaaattat ttacaggacc atttaaatgc ctaaatttta tttaaggcag
5401 tgggtgtcaa agtgtggtcc caagaccagc aacatcaata tcagctggaa acttgttaga
5461 aatgaaaatt gacaggcccc accccacagc tgctgaatca gaaaatctgg gagtggggac
5521 ccatgatctg ttttaagaag cctccctggt gattctaatt catgctcaag tttaagaaca
5581 actgatttaa ggagtcacat atttagcctt cttgcctaga aagaacttta tagtaaggca
5641 gcttagttac tatatacagt taatagcaaa ccttgcctga catactcaga agatgaaata
5701 tccacccaca caaaatgaaa atctactttg acctattttc caggttaaat gatcttgggt
5761 atcttgcttt cactcatgac cacaaattcc catgaaaaac tggaagaata gaatcctggg
5821 gaaaaactaa caggatactt tttatgtgta ctaagacaca agcaaggaaa tattcttaca
5881 gaatttattc acaggagata ggatcaaaat cttaattatt aacattatca tcctatagga
5941 tgctagaata atacttagaa ttttttactt tacagccann naaatttatt gaacaccaac
6001 agtgtggact gaagtacctt acagaacact gataacataa tctttgtctt taagtccttt
6061 tttttttttt cagacgggat ctcattttgt tgccagaatg cagtggcatc atcatggcca
6121 ctgcagcctt gacctcccaa gctcaaggat tctcctgcct tggccttcca aagcgttggg
6181 actacagaca catgccacca tactcggcta attaaataca tatttttttg tagagatgag
6241 gtctcactat attgccccgg ctggtctcaa actcctgggc tcaagcaatc cttccacctt
6301 tacctcctaa agtactggaa ttacaagtgt gagctacggt gcctggcctg agtcttaaat
6361 tcctaacata atgtacattt tttgagcata atacaataca tgacatcatt aagagattac
6421 gtgaacatag actgagacct tttatggtga aatcttgtga gattcactat gttttattta
6481 cgtcttggta actgctgact aaatgtctgg atgaaaatag aggatcttat gtaaaatgag
6541 atgaaaagct atatgtcaag ccacatttgt aatcctttaa cgcttggctt cggtagtcca
6601 aactctacag taacagagcc atctaatggc cactgggacc aattacaagc agattgcctg
6661 ggaattactc agttttcaca gtataatgga accataacgt atgctctgca aataagccat
6721 ttaaaaatca tttctaattg gttttataat acaatatatt tatggaagta tatattccta
6781 atttgtttta gtttggttaa aacatgcaag gaggcagtct tagaagctt
//