GenBank-Updates@genbank.bio.net (10/13/90)
LOCUS FIVPPR 9468 bp ss-RNA VRL 13-OCT-1990
DEFINITION Feline immunodeficiency virus, PPR isolate, complete genome;
(San Diego isolate).
ACCESSION M36968
KEYWORDS complete genome.
SOURCE Feline immunodeficiency virus, clone PPR, genomic DNA. Infectious
clone.
REFERENCE 1 (bases 1 to 9468)
AUTHORS Phillips,T.R., Talbott,R.L., Lamont,C., Muir,S., Lovelace,K. and
Elder,J.H.
TITLE Comparison of two host cell range variants of feline
immunodeficiency virus
JOURNAL J. Virol. 64, 4605-4613 (1990)
STANDARD full automatic
COMMENT Draft entry and computer-readable copy of sequence [1] kindly
provided by T.Phillips.
Scripps Research Foundation, La Jolla CA.
The PPR isolate is approximately 91% homologous to the previously
characterized Petaluma isolate. The latter infected feline kidney
cells and the G355-5 cell line but replicated less efficiently on
feline PBL's. In contrast, PPR productively infects PBL's but not
the other cell lines. The authors point out interesting differences
in the LTRs and coding regions.
The small orfs include: orf 1, in size and position similar to vif
but without statistically significant homology; orf 2 that is "tat"
like; orfs 3 (denoted D in [1]) and 4 (denoted H in [1]) seen also
in the Petaluma strain.
FEATURES from to/span description
pept 628 1980 gag polyprotein
pept / 1869 5243 pol polyprotein (NH2-terminus uncertain; AA at
1869)
pept 5236 5991 orf 1
pept 5992 6225 orf 2
pept 6263 8827 env polyprotein
pept 6709 6915 orf 3 (orf D in [1])
pept 8950 9165 orf 4 (orf H in [1])
BASE COUNT 3605 a 1366 c 2092 g 2405 t
ORIGIN 5' terminus of 5'LTR.
1 tgggatgagt attgggaccc tgaagaaata gaaagaatgc ttatggacta agaactgtca
61 caaacaaatg ataaatggaa acagctgaac atgactcata gttaaagcgc tagcagctgc
121 ttaaccgcaa aaccacatcc tatgtaaagc ttgccaatga cgtataattt gctccactgt
181 aagagtatat aatcagtgct ttgtgaagct tcgaagagtc tctctgctga ggactttcga
241 gttctccctt gaggctccca cagatacaat aaatatttga gattgaaccc tgtcaagtat
301 ctgtgtagtc ttttctacct gtgaggtctc ggaatccggg ccgagaactt cgcagttggc
361 gcccgaacag ggacttgaga aagagtgatt gaggaagtga agctagagca gtagaaagct
421 gttaagcaga actcctgttg acctaaatag ggaagcagta gcagacgctg ctaaacagtg
481 agtatctcta gtgaagcaga ctcgagctca taatcaagtc actgtttaaa ggcccagata
541 aattacattt ggtgactctt cgcggacctt caagccagga gattcgccga gggacagcta
601 acaaggtagg agagactcta cagcaacatg gggaatggac aggggcgaga ttggaaaatg
661 gccattaaga gatgtagtaa tgttgctgta ggagtagggg ggaagagtaa aaaatttgga
721 gaggggaatt ttaggtgggc cataagaatg gctaatgtat ctacaggacg agaacctggt
781 gatataccag agactttaga tcaactaagg ttggttattt gcgatttaca agaaagaaga
841 gaaaaatttg gatctagcaa agaaattgac atggcaatta caacattaaa agtctttgca
901 gtagtgggac ttttaaatat gacagtgtct actgctgctg cagctgaaaa tatgtatact
961 cagatgggat tagacactag accgtctaca aaagaagcgg gaggaaaaga ggaaggccct
1021 ccacaggcat atcctattca aacagtaaat ggagcaccac aatatgtagc acttgaccca
1081 aaaatggtgt ccatttttat ggaaaaggca agagagggat taggaggtga ggaagttcaa
1141 ctatggttta cagccttctc tgcaaattta acacctactg acatggccac attaataatg
1201 gccgcacccg ggtgcgctgc agataaagaa atattggatg aaagcttaaa gcaattgaca
1261 gcagaatatg atcggacaaa tccccctgat ggtcctagac cattacccta ttttactgca
1321 gcagaaatta tgggtatagg attaactcaa gaacaacaag cagaagcaag atttgcacca
1381 gctaggatgc aatgtagagc atggtatctt gaggcattag gaaaattagc cgccataaag
1441 gctaaatctc ctcgagctgt gcagttaaga caaggagcta aggaagatta ttcatccttt
1501 atagacagat tgtttgccca aatagatcaa gaacaaaata cagctgaagt taagttatat
1561 ctaaaacagt cattaagcat agctaatgct aatgcagaat gcaaaaaggc aatgagtcat
1621 cttaagccag aaagtaccct agaagaaaag ttgagagctt gtcaagagat aggatcccca
1681 ggatataaaa tgcaactctt ggcagaagct cttacaaaag ttcaagtagt gcaatcaaaa
1741 ggatcaggac cagtgtgttt taattgtaaa aaaccagggc atctagcaag acagtgtaga
1801 gatgtgaaaa aatgtaataa atgtggaaaa cctggtcatt tagctgccaa atgttggcaa
1861 ggtggtaaaa gaaattcggg aaactggaag gcggggcgag ctgcagcccc agtgaatcaa
1921 gtgcagcaaa cagtaatgcc atctgcacct ccaatggagg aaaaattatt ggatttataa
1981 attacaataa agtaggtact actacatcat tagaaaagag gccagaaata cttatatttg
2041 tgaatgggta ccctataaaa tttttattag atacaggagc agatataaca attttaaata
2101 ggagagattt tcaagtaaaa aactctatag aaaatggaag acaaaatatg attggagtag
2161 ggggaggaaa gagaggaaca aattatatca atgtgcattt agagattaga gatgaaaatt
2221 acaagacaca atgtatattt ggcaatgttt gtgtcttaga agataactca ttaatacaac
2281 cattattagg gagagataat atgattaaat ttaatatcag gttagtaatg gctcaaattt
2341 ctgataagat tccaatagta aaagtaaaga tgaaggatcc taataaagga cctcaaataa
2401 aacaatggcc attatcaaat gaaaaaattg aagctttaac agaaatagta gaaagactag
2461 aaagggaagg gaaagtaaaa agagcagatc caaataatcc atggaataca ccagtatttg
2521 ctataaaaaa gaaaagtgga aaatggagga tgctcataga ttttagagaa ttgaacaaat
2581 taactgagaa aggagcagaa gtccagttgg gactacctca ccctgctggt ttacaaatga
2641 aaaaacaaat aacagtatta gatatagggg atgcatattt caccaatccc cttgacccag
2701 attatgctcc ttatacagca tttactttac ctaggaagaa taatgcggga ccaggaagaa
2761 gatttgtgtg gtgtagtcta ccacaaggct ggattttaag tccattgata tatcaaagta
2821 cattagataa tataatacaa ccttttatta gacaaaatcc tcaattagat atttatcaat
2881 atatggatga catttatata ggatcaaact taagtaaaaa ggagcataaa gaaaaagtag
2941 aagaattaag aaaattacta ttatggtggg gatttgaaac tccagaggat aaattacagg
3001 aagaaccccc atataaatgg atgggttatg aattacatcc attaacatgg acaatacaac
3061 agaaacagtt agaaattcca gaaaagccta cattaaatga attacaaaaa ttagcaggaa
3121 aaattaattg ggctagccaa actattccag aattaagtat aaaatcatta actaacatga
3181 cgagaggaaa tcaaaaccta aattcaacaa gagagtggac tgaggaagct agactagaag
3241 tacagaaggc caaaagggct attgaagaac aagtacaact aggatattat gaccctagta
3301 aagaattgta tgctaaatta agcttagtgg gaccacatca aataagttat caagtatatc
3361 agaagtgtcc agaaaagatc ttatggtatg gaaaaatgag taggcaaaag aaaaaggcag
3421 aaaatacgtg tgatatagcg ttaagagcat gctacaaaat aagggaagaa tccattataa
3481 gaataggaaa agaaccaaga tatgaaatac ctacttctag agaagcctgg gaatcaaatt
3541 taattaattc accatatctt aaagccccac ctccagaagt agactatatc catgctgctt
3601 taaacataaa aagagcacta agtatgataa aagatcctcc aatatcagga gcagaaacgt
3661 ggtatataga tggaggtaga aagctaggaa aagcagcaaa agcagcctat tggacagata
3721 caggaaagtg gcaagtaatg gaattagaag gtagtaatca gaaggcggaa atacaagcat
3781 tattattggc attaaaggca ggaccagagg aaatgaatat tataacagat tctcagtata
3841 tgataaatat tcttagtcaa caaccagata agatggaagg aatctggcaa gaagttttag
3901 aagaattgga aaagaaaaca gcaatattta tagattgggt cccaggacat aaaggtattc
3961 caggaaatga ggaagtagat aagctttgtc aaacaatgat gataatagaa ggggatggga
4021 tattagataa aagaacagaa gatgcaggat atgatttatt agctgcaaaa gaaatacatc
4081 tattaccagg agaggtaaaa gtaataccaa cgggagtaaa actaatgttg cctaaaggac
4141 attggggatt aataatggga aaaagctcga tagggagtaa aggattggat gtattaggag
4201 gggtaataga tgaaggatat cgaggtgaaa ttggagtaat aatgattaat ttatcaaaaa
4261 aatcaatcac tttgttggaa caacagaaga tagcacaatt aataatattg cctcataaac
4321 atgaagcatt agaacagggg aaagtagtaa tggattcaga gagaggagaa aaaggttatg
4381 ggtcaacagg agtattctcc tcttgggttg acagaattga ggaagcagaa acaaatcatg
4441 aaaaatttca ctcagatccg caatacttaa ggactgaatt taatttaccc aagatggtgg
4501 cagaagagat aagacgaaaa tgccctgtat gtaggattag aggagaacaa gtgggagggc
4561 aattgaagat agggcctggt atctggcaaa tggattgcac acactttgat ggcaaaataa
4621 ttcttgtggc tatacatgtg gaatcaggat atatatgggc acaaataatc tctcaagaaa
4681 ctgctgattg tacagttaaa gctgtcttac aattattgag tgctcatatt gttacggagt
4741 tacaaacaga taatggacca aattttaaaa atcaaaagat ggaaggagta ctcaattata
4801 tgggtgtgaa acataagttt ggtatcccag gaaacccaca atcacaagca ttagttgaaa
4861 atgtaaatca gacattaaaa gtctgggttc acaaattttt gcctgaaaca acctccttgg
4921 ataatgcatt agctctcgct gtgcattgtc tcaattttaa acaaaggggt agaataggag
4981 ggatggcccc ttatgaatta ttagcacaac aagaatcctt aagaatacaa gattatttct
5041 ctgcaatacc acaaaaattg caagcacaat ggatttatta taaagatcaa aaagataaga
5101 aatggaaagg gccaatgaga gtagaatact ggggacaagg atcagtgtta ttaaaggatg
5161 aagagaaggg atattttctt atacctagga gacacgtaaa gagagtccca gaaccctgcg
5221 ctcttcctga aggggatgag tgacgaagat tggcaggtaa gtagaagact ctttgcagtg
5281 ctccaaggag gggtatataa cgctatgcta tatatatcta gactacctca ggacgaaaga
5341 gaaaaatata aaaaggattt caagaaaaga cttttagata cagaaacagg atttataaaa
5401 agactaagga aagctgaagg aataaaatgg agctttcata ctagagatta tcatgtagga
5461 tatgttagag aaatggtagc aggacccact acaccacata gtctaaggct gtatgtgtat
5521 ataagtaatc cactatggca ttctcagtat cgtccaggct tggtaaattt taataaggaa
5581 tggccttttg taaatctatg gataaaaaca ggatttatgt gggatgatat tgaaaaacaa
5641 aatatttgta taggaggaga agtttcacca ggatggggac ctgggatgat aggtatagcg
5701 ataaaagctt ttagttgtgg cgaaagaaag attgaggcta ctcctgtaat gattataaga
5761 ggagaaataa atccaaaaaa atggtgtgga gactgttgga atttgatgtg tcttagaaac
5821 tcacctccag agactttaca aaggctcgct atgttggcat gtggagtaca ggctaagagc
5881 tggcgaggat gctgtaatca acgttttgtt tctccttaca gaacacctgc tgatttagag
5941 gttattcaat ccaaacccgg ctggtgcatg ttatggcgag gaaaactgtg aatggaagta
6001 atacggatat ttaataaggt cgctgaaaga ttagacaagg aagcagccat caggatattt
6061 gtattagcac atcaattaga gagggataaa ttgattagac ttctgcaagg actactttgg
6121 agactgagat ttagaaaacc taaatcaaaa gattgtttat gttggttttg ctgcagatta
6181 tattattggc agttgcagtc tacattatcc atagatactg cttagaaata tttataataa
6241 tatttcattt gcaacaataa ttatggcaga agggtttgca gccaatagac aatggatagg
6301 gccagaagaa gctgaagagc tattagattt tgataaagca acacaaatga atgaagaagg
6361 gccactaaat ccaggagtaa acccatttag agtacctgca gtaacagaag cagacaagca
6421 agaatattgt aagatattac aaccccgatt acaagagata aggaatgaaa ttcaagaagt
6481 aaaactagaa gaaggaaatg caggtaagtt tagaagagca agattcttga gatattctga
6541 tgaaagtata ttatccttaa ttcatttgtt catagggtat tgtacatact tagtaaatag
6601 aaggaggtta ggatctttaa ggcatgacat aaatatagaa gcgcctcaag aagagcagta
6661 tagcagtaga gagcagggca caactgagaa tataaaatat ggtagacgat gcttgatagg
6721 aacagcaagt ctgtacttgt tgctttttat aggagtggca atatatttag gtacaaccaa
6781 tgctcagata gtatggagac ttccaccatt agtagtccca gtagaagaat cagaaataat
6841 tttttgggat tgttgggcac cagaggagcc cgcctgtcaa gactttcttg gggcaatgat
6901 acatctaaaa gctagtacaa atataagtat acaagaagga cctaccttgg ggaattgggc
6961 tagagaaata tggggaacat tattcaaaaa agctactaga cattgtagga gaaataaaat
7021 atggaaaagg tggaatgaaa ctataacagg accagtagga tgtgctaata atacatgtta
7081 taatatctct gtaataatac ctgattatca atgttatcta gatagagtag atacttggtt
7141 acaagggaaa gtaaatatat cattatgcct aacaggagga aaaatgttgt ataatagaga
7201 tacaaaacaa ttaagctatt gtacagaccc attacaaatc ccactgatca attatacatt
7261 tgggcctaat caaacatgta tgtggaacac ttcacagatt caagacccgg agataccaaa
7321 atgtggatgg tggaatcaaa tagcctatta taacagttgt agatgggaaa gcacaaatgt
7381 aaagttttat tgtcaaagaa cacagagtca gcctggaaca tggattagaa caatctcatc
7441 atggagacaa aagaatagat gggaatggag accagacttt gaaagcgaaa aagttaaaat
7501 atcattacaa tgtaatagta cacataattt aacttttgca atgagaagtt caggagatta
7561 tggagaagta atgggagctt ggatagaatt tggatgtcat aggaacaaat caagattcca
7621 tactgaagca aggtttagaa ttagatgtag atggaatgta ggggataata cctcactcat
7681 tgatacatgt ggaaaaaatc taaatgtttc aggtgccaat cctgtagatt gtaccatgta
7741 tgcaaataaa atgtataact gttccttaca aaacgggttt actatgaagg tagatgacct
7801 tattatgcat ttcaatatga caaaagcagt agaaatgtat aacattgctg ggaattggtc
7861 ttgtaaatct gatttaccac aaaattgggg atatatgaat tgtaattgta cgaatggtac
7921 gagtaatgac aataaaatgg catgtcctga agataagggt atcttaagaa attggtataa
7981 tccagtagca ggattaagac aagcattaga aaaatatcaa gtggtaaaac agccagaata
8041 tatagtagta ccaacagaag ttatgaccta taaatacaaa cagaaaagag cagcaattca
8101 tattatgtta gctcttgcaa cagtattgtc tatagctggg gcaggaacag gtgctacagc
8161 aattgggatg gtgactcaat atcagcaagt tttagctact catcaagaag cattggataa
8221 aataactgaa gcattgaaaa taaataattt aaggttagtt actttagagc atcaaatgtt
8281 agtcatagga ttgaaagtag aagctataga aaaattttta tatactgctt ttgctatgca
8341 agaactagga tgtaatcaaa atcaattctt ttgtgaaatt cccaaagagc tatggctaag
8401 gtataatatg acattaaatc aaacaatttg gaatcatgga aatataactt taggggaatg
8461 gtacaatcag acaaaatatt tacaacaaaa attttatgaa ataattatgg atatagaaca
8521 aaataatgta caaggaaaac aaggattaca aaaattacaa aattggcaag attggatggg
8581 atggatagga aaaatacctc aatacttaaa gggactcttg ggaggcattt tgggaatagg
8641 tttgggaatt ctattattga ttttatgttt acccacttta gttgattgta ttagaaattg
8701 tattagtaaa gttctaggat atacagtaat cgcaatgcct gagatagatg atgaagaaga
8761 aacggtacaa atggaattga ggaaaaatgg caggcaatgt ggcatgtctg aaaaagagga
8821 ggaatgatgg agtgcctcag aactgcttaa tgcaggagag gtgctgagct gatttcttcc
8881 ctttgaggaa gatatgtcat atgaatccat tttgaatcaa aataataagt atttgtatta
8941 taaggtaaaa tgaaaaagaa aagacaaaga agaagaagaa agaagaaggc ctttaagaaa
9001 atgatgacag atttagaaga ccgcttcaga aaactattcg gctcaccctc taaagatgaa
9061 tacacagaaa ttgagataga agaagaccct cctaaaaaag aaaaaagggt ggactgggat
9121 gagtattggg accctgaaga aatagaaaga atgcttatgg actaagaact gtcacaaaca
9181 aatgataaat ggaaacagct gaacatgact catagttaaa gcgctagcag ctgcttaacc
9241 gcaaaaccac atcctatgta aagcttgcca atgacgtata atttgctcca ctgtaagagt
9301 atataatcag tgctttgtga agcttcgaag agtctctctg ctgaggactt tcgagttctc
9361 ccttgaggct cccacagata caataaatat ttgagattga accctgtcaa gtatctgtgt
9421 agtcttttct acctgtgagg tctcggaatc cgggccgaga acttcgca
//GenBank-Updates@genbank.bio.net (10/16/90)
LOCUS FIVPPR 9468 bp ss-RNA VRL 16-OCT-1990
DEFINITION Feline immunodeficiency virus, PPR isolate, complete genome;
(San Diego isolate).
ACCESSION M36968
KEYWORDS complete genome.
SOURCE Feline immunodeficiency virus, clone PPR, genomic DNA. Infectious
clone.
ORGANISM Feline immunodeficiency virus
Viridae; ss-RNA enveloped viruses; Positive strand RNA virus;
Retroviridae; Lentivirinae.
REFERENCE 1 (bases 1 to 9468)
AUTHORS Phillips,T.R., Talbott,R.L., Lamont,C., Muir,S., Lovelace,K. and
Elder,J.H.
TITLE Comparison of two host cell range variants of feline
immunodeficiency virus
JOURNAL J. Virol. 64, 4605-4613 (1990)
STANDARD full automatic
COMMENT Draft entry and computer-readable copy of sequence [1] kindly
provided by T.Phillips.
Scripps Research Foundation, La Jolla CA.
The PPR isolate is approximately 91% homologous to the previously
characterized Petaluma isolate. The latter infected feline kidney
cells and the G355-5 cell line but replicated less efficiently on
feline PBL's. In contrast, PPR productively infects PBL's but not
the other cell lines. The authors point out interesting differences
in the LTRs and coding regions.
The small orfs include: orf 1, in size and position similar to vif
but without statistically significant homology; orf 2 that is "tat"
like; orfs 3 (denoted D in [1]) and 4 (denoted H in [1]) seen also
in the Petaluma strain.
FEATURES from to/span description
pept 628 1980 gag polyprotein
pept / 1869 5243 pol polyprotein (NH2-terminus uncertain; AA at
1869)
pept 5236 5991 orf 1
pept 5992 6225 orf 2
pept 6263 8827 env polyprotein
pept 6709 6915 orf 3 (orf D in [1])
pept 8950 9165 orf 4 (orf H in [1])
BASE COUNT 3605 a 1366 c 2092 g 2405 t
ORIGIN 5' terminus of 5'LTR.
1 tgggatgagt attgggaccc tgaagaaata gaaagaatgc ttatggacta agaactgtca
61 caaacaaatg ataaatggaa acagctgaac atgactcata gttaaagcgc tagcagctgc
121 ttaaccgcaa aaccacatcc tatgtaaagc ttgccaatga cgtataattt gctccactgt
181 aagagtatat aatcagtgct ttgtgaagct tcgaagagtc tctctgctga ggactttcga
241 gttctccctt gaggctccca cagatacaat aaatatttga gattgaaccc tgtcaagtat
301 ctgtgtagtc ttttctacct gtgaggtctc ggaatccggg ccgagaactt cgcagttggc
361 gcccgaacag ggacttgaga aagagtgatt gaggaagtga agctagagca gtagaaagct
421 gttaagcaga actcctgttg acctaaatag ggaagcagta gcagacgctg ctaaacagtg
481 agtatctcta gtgaagcaga ctcgagctca taatcaagtc actgtttaaa ggcccagata
541 aattacattt ggtgactctt cgcggacctt caagccagga gattcgccga gggacagcta
601 acaaggtagg agagactcta cagcaacatg gggaatggac aggggcgaga ttggaaaatg
661 gccattaaga gatgtagtaa tgttgctgta ggagtagggg ggaagagtaa aaaatttgga
721 gaggggaatt ttaggtgggc cataagaatg gctaatgtat ctacaggacg agaacctggt
781 gatataccag agactttaga tcaactaagg ttggttattt gcgatttaca agaaagaaga
841 gaaaaatttg gatctagcaa agaaattgac atggcaatta caacattaaa agtctttgca
901 gtagtgggac ttttaaatat gacagtgtct actgctgctg cagctgaaaa tatgtatact
961 cagatgggat tagacactag accgtctaca aaagaagcgg gaggaaaaga ggaaggccct
1021 ccacaggcat atcctattca aacagtaaat ggagcaccac aatatgtagc acttgaccca
1081 aaaatggtgt ccatttttat ggaaaaggca agagagggat taggaggtga ggaagttcaa
1141 ctatggttta cagccttctc tgcaaattta acacctactg acatggccac attaataatg
1201 gccgcacccg ggtgcgctgc agataaagaa atattggatg aaagcttaaa gcaattgaca
1261 gcagaatatg atcggacaaa tccccctgat ggtcctagac cattacccta ttttactgca
1321 gcagaaatta tgggtatagg attaactcaa gaacaacaag cagaagcaag atttgcacca
1381 gctaggatgc aatgtagagc atggtatctt gaggcattag gaaaattagc cgccataaag
1441 gctaaatctc ctcgagctgt gcagttaaga caaggagcta aggaagatta ttcatccttt
1501 atagacagat tgtttgccca aatagatcaa gaacaaaata cagctgaagt taagttatat
1561 ctaaaacagt cattaagcat agctaatgct aatgcagaat gcaaaaaggc aatgagtcat
1621 cttaagccag aaagtaccct agaagaaaag ttgagagctt gtcaagagat aggatcccca
1681 ggatataaaa tgcaactctt ggcagaagct cttacaaaag ttcaagtagt gcaatcaaaa
1741 ggatcaggac cagtgtgttt taattgtaaa aaaccagggc atctagcaag acagtgtaga
1801 gatgtgaaaa aatgtaataa atgtggaaaa cctggtcatt tagctgccaa atgttggcaa
1861 ggtggtaaaa gaaattcggg aaactggaag gcggggcgag ctgcagcccc agtgaatcaa
1921 gtgcagcaaa cagtaatgcc atctgcacct ccaatggagg aaaaattatt ggatttataa
1981 attacaataa agtaggtact actacatcat tagaaaagag gccagaaata cttatatttg
2041 tgaatgggta ccctataaaa tttttattag atacaggagc agatataaca attttaaata
2101 ggagagattt tcaagtaaaa aactctatag aaaatggaag acaaaatatg attggagtag
2161 ggggaggaaa gagaggaaca aattatatca atgtgcattt agagattaga gatgaaaatt
2221 acaagacaca atgtatattt ggcaatgttt gtgtcttaga agataactca ttaatacaac
2281 cattattagg gagagataat atgattaaat ttaatatcag gttagtaatg gctcaaattt
2341 ctgataagat tccaatagta aaagtaaaga tgaaggatcc taataaagga cctcaaataa
2401 aacaatggcc attatcaaat gaaaaaattg aagctttaac agaaatagta gaaagactag
2461 aaagggaagg gaaagtaaaa agagcagatc caaataatcc atggaataca ccagtatttg
2521 ctataaaaaa gaaaagtgga aaatggagga tgctcataga ttttagagaa ttgaacaaat
2581 taactgagaa aggagcagaa gtccagttgg gactacctca ccctgctggt ttacaaatga
2641 aaaaacaaat aacagtatta gatatagggg atgcatattt caccaatccc cttgacccag
2701 attatgctcc ttatacagca tttactttac ctaggaagaa taatgcggga ccaggaagaa
2761 gatttgtgtg gtgtagtcta ccacaaggct ggattttaag tccattgata tatcaaagta
2821 cattagataa tataatacaa ccttttatta gacaaaatcc tcaattagat atttatcaat
2881 atatggatga catttatata ggatcaaact taagtaaaaa ggagcataaa gaaaaagtag
2941 aagaattaag aaaattacta ttatggtggg gatttgaaac tccagaggat aaattacagg
3001 aagaaccccc atataaatgg atgggttatg aattacatcc attaacatgg acaatacaac
3061 agaaacagtt agaaattcca gaaaagccta cattaaatga attacaaaaa ttagcaggaa
3121 aaattaattg ggctagccaa actattccag aattaagtat aaaatcatta actaacatga
3181 cgagaggaaa tcaaaaccta aattcaacaa gagagtggac tgaggaagct agactagaag
3241 tacagaaggc caaaagggct attgaagaac aagtacaact aggatattat gaccctagta
3301 aagaattgta tgctaaatta agcttagtgg gaccacatca aataagttat caagtatatc
3361 agaagtgtcc agaaaagatc ttatggtatg gaaaaatgag taggcaaaag aaaaaggcag
3421 aaaatacgtg tgatatagcg ttaagagcat gctacaaaat aagggaagaa tccattataa
3481 gaataggaaa agaaccaaga tatgaaatac ctacttctag agaagcctgg gaatcaaatt
3541 taattaattc accatatctt aaagccccac ctccagaagt agactatatc catgctgctt
3601 taaacataaa aagagcacta agtatgataa aagatcctcc aatatcagga gcagaaacgt
3661 ggtatataga tggaggtaga aagctaggaa aagcagcaaa agcagcctat tggacagata
3721 caggaaagtg gcaagtaatg gaattagaag gtagtaatca gaaggcggaa atacaagcat
3781 tattattggc attaaaggca ggaccagagg aaatgaatat tataacagat tctcagtata
3841 tgataaatat tcttagtcaa caaccagata agatggaagg aatctggcaa gaagttttag
3901 aagaattgga aaagaaaaca gcaatattta tagattgggt cccaggacat aaaggtattc
3961 caggaaatga ggaagtagat aagctttgtc aaacaatgat gataatagaa ggggatggga
4021 tattagataa aagaacagaa gatgcaggat atgatttatt agctgcaaaa gaaatacatc
4081 tattaccagg agaggtaaaa gtaataccaa cgggagtaaa actaatgttg cctaaaggac
4141 attggggatt aataatggga aaaagctcga tagggagtaa aggattggat gtattaggag
4201 gggtaataga tgaaggatat cgaggtgaaa ttggagtaat aatgattaat ttatcaaaaa
4261 aatcaatcac tttgttggaa caacagaaga tagcacaatt aataatattg cctcataaac
4321 atgaagcatt agaacagggg aaagtagtaa tggattcaga gagaggagaa aaaggttatg
4381 ggtcaacagg agtattctcc tcttgggttg acagaattga ggaagcagaa acaaatcatg
4441 aaaaatttca ctcagatccg caatacttaa ggactgaatt taatttaccc aagatggtgg
4501 cagaagagat aagacgaaaa tgccctgtat gtaggattag aggagaacaa gtgggagggc
4561 aattgaagat agggcctggt atctggcaaa tggattgcac acactttgat ggcaaaataa
4621 ttcttgtggc tatacatgtg gaatcaggat atatatgggc acaaataatc tctcaagaaa
4681 ctgctgattg tacagttaaa gctgtcttac aattattgag tgctcatatt gttacggagt
4741 tacaaacaga taatggacca aattttaaaa atcaaaagat ggaaggagta ctcaattata
4801 tgggtgtgaa acataagttt ggtatcccag gaaacccaca atcacaagca ttagttgaaa
4861 atgtaaatca gacattaaaa gtctgggttc acaaattttt gcctgaaaca acctccttgg
4921 ataatgcatt agctctcgct gtgcattgtc tcaattttaa acaaaggggt agaataggag
4981 ggatggcccc ttatgaatta ttagcacaac aagaatcctt aagaatacaa gattatttct
5041 ctgcaatacc acaaaaattg caagcacaat ggatttatta taaagatcaa aaagataaga
5101 aatggaaagg gccaatgaga gtagaatact ggggacaagg atcagtgtta ttaaaggatg
5161 aagagaaggg atattttctt atacctagga gacacgtaaa gagagtccca gaaccctgcg
5221 ctcttcctga aggggatgag tgacgaagat tggcaggtaa gtagaagact ctttgcagtg
5281 ctccaaggag gggtatataa cgctatgcta tatatatcta gactacctca ggacgaaaga
5341 gaaaaatata aaaaggattt caagaaaaga cttttagata cagaaacagg atttataaaa
5401 agactaagga aagctgaagg aataaaatgg agctttcata ctagagatta tcatgtagga
5461 tatgttagag aaatggtagc aggacccact acaccacata gtctaaggct gtatgtgtat
5521 ataagtaatc cactatggca ttctcagtat cgtccaggct tggtaaattt taataaggaa
5581 tggccttttg taaatctatg gataaaaaca ggatttatgt gggatgatat tgaaaaacaa
5641 aatatttgta taggaggaga agtttcacca ggatggggac ctgggatgat aggtatagcg
5701 ataaaagctt ttagttgtgg cgaaagaaag attgaggcta ctcctgtaat gattataaga
5761 ggagaaataa atccaaaaaa atggtgtgga gactgttgga atttgatgtg tcttagaaac
5821 tcacctccag agactttaca aaggctcgct atgttggcat gtggagtaca ggctaagagc
5881 tggcgaggat gctgtaatca acgttttgtt tctccttaca gaacacctgc tgatttagag
5941 gttattcaat ccaaacccgg ctggtgcatg ttatggcgag gaaaactgtg aatggaagta
6001 atacggatat ttaataaggt cgctgaaaga ttagacaagg aagcagccat caggatattt
6061 gtattagcac atcaattaga gagggataaa ttgattagac ttctgcaagg actactttgg
6121 agactgagat ttagaaaacc taaatcaaaa gattgtttat gttggttttg ctgcagatta
6181 tattattggc agttgcagtc tacattatcc atagatactg cttagaaata tttataataa
6241 tatttcattt gcaacaataa ttatggcaga agggtttgca gccaatagac aatggatagg
6301 gccagaagaa gctgaagagc tattagattt tgataaagca acacaaatga atgaagaagg
6361 gccactaaat ccaggagtaa acccatttag agtacctgca gtaacagaag cagacaagca
6421 agaatattgt aagatattac aaccccgatt acaagagata aggaatgaaa ttcaagaagt
6481 aaaactagaa gaaggaaatg caggtaagtt tagaagagca agattcttga gatattctga
6541 tgaaagtata ttatccttaa ttcatttgtt catagggtat tgtacatact tagtaaatag
6601 aaggaggtta ggatctttaa ggcatgacat aaatatagaa gcgcctcaag aagagcagta
6661 tagcagtaga gagcagggca caactgagaa tataaaatat ggtagacgat gcttgatagg
6721 aacagcaagt ctgtacttgt tgctttttat aggagtggca atatatttag gtacaaccaa
6781 tgctcagata gtatggagac ttccaccatt agtagtccca gtagaagaat cagaaataat
6841 tttttgggat tgttgggcac cagaggagcc cgcctgtcaa gactttcttg gggcaatgat
6901 acatctaaaa gctagtacaa atataagtat acaagaagga cctaccttgg ggaattgggc
6961 tagagaaata tggggaacat tattcaaaaa agctactaga cattgtagga gaaataaaat
7021 atggaaaagg tggaatgaaa ctataacagg accagtagga tgtgctaata atacatgtta
7081 taatatctct gtaataatac ctgattatca atgttatcta gatagagtag atacttggtt
7141 acaagggaaa gtaaatatat cattatgcct aacaggagga aaaatgttgt ataatagaga
7201 tacaaaacaa ttaagctatt gtacagaccc attacaaatc ccactgatca attatacatt
7261 tgggcctaat caaacatgta tgtggaacac ttcacagatt caagacccgg agataccaaa
7321 atgtggatgg tggaatcaaa tagcctatta taacagttgt agatgggaaa gcacaaatgt
7381 aaagttttat tgtcaaagaa cacagagtca gcctggaaca tggattagaa caatctcatc
7441 atggagacaa aagaatagat gggaatggag accagacttt gaaagcgaaa aagttaaaat
7501 atcattacaa tgtaatagta cacataattt aacttttgca atgagaagtt caggagatta
7561 tggagaagta atgggagctt ggatagaatt tggatgtcat aggaacaaat caagattcca
7621 tactgaagca aggtttagaa ttagatgtag atggaatgta ggggataata cctcactcat
7681 tgatacatgt ggaaaaaatc taaatgtttc aggtgccaat cctgtagatt gtaccatgta
7741 tgcaaataaa atgtataact gttccttaca aaacgggttt actatgaagg tagatgacct
7801 tattatgcat ttcaatatga caaaagcagt agaaatgtat aacattgctg ggaattggtc
7861 ttgtaaatct gatttaccac aaaattgggg atatatgaat tgtaattgta cgaatggtac
7921 gagtaatgac aataaaatgg catgtcctga agataagggt atcttaagaa attggtataa
7981 tccagtagca ggattaagac aagcattaga aaaatatcaa gtggtaaaac agccagaata
8041 tatagtagta ccaacagaag ttatgaccta taaatacaaa cagaaaagag cagcaattca
8101 tattatgtta gctcttgcaa cagtattgtc tatagctggg gcaggaacag gtgctacagc
8161 aattgggatg gtgactcaat atcagcaagt tttagctact catcaagaag cattggataa
8221 aataactgaa gcattgaaaa taaataattt aaggttagtt actttagagc atcaaatgtt
8281 agtcatagga ttgaaagtag aagctataga aaaattttta tatactgctt ttgctatgca
8341 agaactagga tgtaatcaaa atcaattctt ttgtgaaatt cccaaagagc tatggctaag
8401 gtataatatg acattaaatc aaacaatttg gaatcatgga aatataactt taggggaatg
8461 gtacaatcag acaaaatatt tacaacaaaa attttatgaa ataattatgg atatagaaca
8521 aaataatgta caaggaaaac aaggattaca aaaattacaa aattggcaag attggatggg
8581 atggatagga aaaatacctc aatacttaaa gggactcttg ggaggcattt tgggaatagg
8641 tttgggaatt ctattattga ttttatgttt acccacttta gttgattgta ttagaaattg
8701 tattagtaaa gttctaggat atacagtaat cgcaatgcct gagatagatg atgaagaaga
8761 aacggtacaa atggaattga ggaaaaatgg caggcaatgt ggcatgtctg aaaaagagga
8821 ggaatgatgg agtgcctcag aactgcttaa tgcaggagag gtgctgagct gatttcttcc
8881 ctttgaggaa gatatgtcat atgaatccat tttgaatcaa aataataagt atttgtatta
8941 taaggtaaaa tgaaaaagaa aagacaaaga agaagaagaa agaagaaggc ctttaagaaa
9001 atgatgacag atttagaaga ccgcttcaga aaactattcg gctcaccctc taaagatgaa
9061 tacacagaaa ttgagataga agaagaccct cctaaaaaag aaaaaagggt ggactgggat
9121 gagtattggg accctgaaga aatagaaaga atgcttatgg actaagaact gtcacaaaca
9181 aatgataaat ggaaacagct gaacatgact catagttaaa gcgctagcag ctgcttaacc
9241 gcaaaaccac atcctatgta aagcttgcca atgacgtata atttgctcca ctgtaagagt
9301 atataatcag tgctttgtga agcttcgaag agtctctctg ctgaggactt tcgagttctc
9361 ccttgaggct cccacagata caataaatat ttgagattga accctgtcaa gtatctgtgt
9421 agtcttttct acctgtgagg tctcggaatc cgggccgaga acttcgca
//