GenBank-Updates@genbank.bio.net (10/17/90)
LOCUS HUMMHB27D 3649 bp ds-DNA PRI 17-OCT-1990
DEFINITION Human MHC class I HLA-B27d gene, complete cds.
ACCESSION M54883 M37272
KEYWORDS cell surface antigen; cell surface glycoprotein; class I gene;
integral membrane protein.
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3649)
AUTHORS Choo,S., Yoon,St., John,T., Orr,H.T. and Hansen,J.A.
TITLE Molecular analysis of the variant alloantigen HLA-B27d (HLA-B*2703)
identifies a unique single amino acid substitution
JOURNAL Hum. Immunol. 21, 209-219 (1988)
STANDARD simple staff_entry
FEATURES from to/span description
pept 87 159 MHC HLA-B27d, exon 1
287 556 MHC HLA-B27d, exon 2
798 1073 MHC HLA-B27d, exon 3
1649 1924 MHC HLA-B27d, exon 4
2018 2134 MHC HLA-B27d, exon 5
2576 2608 MHC HLA-B27d, exon 6
2715 2758 MHC HLA-B27d, exon 7
IVS 160 286 MHC HLA-B27d intron 1
IVS 557 797 MHC HLA-B27d intron 2
IVS 1074 1648 MHC HLA-B27d intron 3
IVS 1925 2017 MHC HLA-B27d intron 4
IVS 2135 2575 MHC HLA-B27d intron 5
IVS 2609 2714 MHC HLA-B27d intron 6
BASE COUNT 690 a 1024 c 1133 g 802 t
ORIGIN
1 ctagagaagc caatcagtgt cgccggggtc ccagttctaa agtccccacg cacccacccg
61 gactcagaat ctcctcagac gccgagatgc gggtcacggc gccccgaacc ctcctcctgc
121 tgctctgggg ggcagtggcc ctgaccgaga cctgggctgg tgagtgcggg gtcggcaggg
181 aaatggcctc tgtggggagg agcgagggga ccgcagcggg gcgcaggacc cggggagccg
241 cgccgggagg agggtcgggc gggtctcagc ccctcctcgc ccccaggctc ccactccatg
301 aggtatttcc acacctccgt gtcccggccc ggccgcgggg agccccgctt catcaccgtg
361 ggctacgtgg acgacacgct gttcgtgagg ttcgacagcg acgccgcgag tccgagagag
421 gagccgcggg cgccgtggat agagcaggag gggccggagc attgggaccg ggagacacag
481 atctgcaagg ccaaggcaca gactgaccga gaggacctgc ggaccctgct ccgctactac
541 aaccagagcg aggccggtga gtgaccccgg cccggggcgc aggtcacgac tccccatccc
601 ccacgtacgg cccgggtcgc cccgagtctc cgggtccgag atccgccccc gaggccgcgg
661 gacccgccca gaccctcgac cggcgagacg ccaggcgcgt ttacccggtt tcattttcag
721 ttgaggccaa aatccccgcg ggttggtcgg ggcggggcgg ggctcggggg gacggggctg
781 acgcggggcg gggccagggt ctcacaccct ccagaatatg tatggctgcg acgtggggcc
841 ggacgggcgc ctcctccgcg ggtaccacca ggacgcctac gacggcaagg attacatcgc
901 cctgaacgag gacctgagct cctggaccgc cgcggacacg gcggctcaga tcacccagcg
961 caagtgggag gcggcccgtg tggcggagca gctgagagcc tacctggagg gcgagtgcgt
1021 ggagtggctc cgcagatacc tggagaacgg gaaggagacg ctgcagcgcg cgggtaccag
1081 gggcagtggg gagccttccc catctcctat aggtcgccgg ggatggcctc ccacgagaag
1141 aggaggaaaa tgggatcagc gctagaatgt cgccctccct tgaatggaga atggcatgag
1201 ttttcctgag tttcctctga gggccccctc ttctctctag gacaattaag ggatgacgtc
1261 tctgaggaaa tggaggggaa gacagtccct agaatactga tcaggggtcc cctttgaccc
1321 ctgcagcagc cttgggaacc gtgacttttc ctctcaggcc ttgttctctg cctcacactc
1381 agtgtgtttg gggctctgat tccagcactt ctgagtcact ttacctccac tcagatcagg
1441 agcagaagtc cctgttcccc gctcagagac tcgaactttc caatgaatag gagattatcc
1501 caggtgcctg cgtccaggct ggtgtctggg ttctgtgccc cttccccacc ccaggtgtcc
1561 tgtccattct caggctggtc acatgggtgg tcctagggtg tcccatgaga gatgcaaagc
1621 gcctgaattt tctgactctt cccatcagac cccccaaaga cacacgtgac ccaccacccc
1681 atctctgacc atgaggccac cctgaggtgc tgggccctgg gcttctaccc tgcggagatc
1741 acactgacct ggcagcggga tggcgaggac caaactcagg acactgagct tgtggagacc
1801 agaccagcag gagatagaac cttccagaag tgggcagctg tggtggtgcc ttctggagaa
1861 gagcagagat acacatgcca tgtacagcat gaggggctgc cgaagcccct caccctgaga
1921 tggggtaagg agggggatga ggggtcatat ctcttctcag ggaaagcagg agcccttcag
1981 cagggtcagg gcccctcatc ttcccttcct ttcccagagc cgtcttccca gtccaccgtc
2041 cccatcgtgg gcattgttgc tggcctggct gtcctagcag ttgtggtcat cggagctgtg
2101 gtcgctgctg tgatgtgtag gaggaagagc tcaggtaggg aaggggtgag gggtggggtc
2161 tgagttttct tgtcccactg ggggtttcaa gccccaggta gaagtgttcc ctgcctcatt
2221 actgggaagc agcatccaca caggggctaa cgcagcctgg gaccctgtgt gccagcactt
2281 actcttttgt gcagcacatg tgacaatgaa tgacggatgt atcaccttgg tggttgtggt
2341 gttggggtcc tgattccagc attcatgagt caggggaagg tccctgctaa ggacagacct
2401 taggagggca gttggtccag gacccacact tgctttcctc gtgtttcctg atcctgcctt
2461 gggtctgtag tcatacttct ggaaattcct tttgggtcca agacgaggag gttcctctaa
2521 gatctcatgg ccctgcttcc tcccagtccc ctcacagggc attttcttcc cacaggtgga
2581 aaaggaggga gctactctca ggctgcgtgt aagtgatggg ggtgggagtg tggaggagct
2641 cacccacccc ctaattcctc ctgtcccacg tctcctgcgg gctctgacca ggtcctgttt
2701 ttgttctact ccaggcagcg acagtgccca gggctctgat gtgtctctca cagcttgaaa
2761 aggtgagatt cttggggtct agagtgggtg gggtggcagg tctgggggtg ggtggggcag
2821 tggggaaagg cctgggtaat ggagattctt tgattgggat gtttcgcgtg tggtgggctg
2881 tttagactgt catcacttac catgactaac cagaatttgt tcatgactgt tgttttctgt
2941 agcctgagac agctgtcttg tgagggactg agatgcagga tttcttcacg cctccccttt
3001 gtgacttcaa gagcctctgg catctctttc tgcaaaggca cctgaatgtg tctgcgtccc
3061 tgttagcata atgtgaggag gtggagagac cagcccaccc ccgtgtccac tgtgacccct
3121 gttcccatgc tgacctgtgt ttcctcccca gtcatctttc ctgttccaga gaggtggggc
3181 tggatgtctc catctctgtc tcaactttat gtgcactgag ctgcaacttc ttacttccct
3241 actgaaaata agaatctgaa tataaatttg ttttctcaaa tatttgctat gagaggttga
3301 tggattaatt aaataagtca attcctggaa tttgagagag caaataaaga cctgagaacc
3361 ttccagaatc tgcatgttgg ctgtgctgag tctgttgcag gtggggtgtg gagaaggctg
3421 tggggggccg agtgtggacg gggcctgtgc ccatttggtg ttgagtccat catgggcttt
3481 atgtggttag tcctcagctg ggtcaccttc actgctccat tgtccttgtc ccttcagtgg
3541 aaacttgtcc agcgggagct gtgaccacag aggctcacac atgccctggg cggcccctgc
3601 acacgggggt ctctgtgcat tctgagacaa attttcagag ccattcacc
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