GenBank-Updates@genbank.bio.net (11/03/90)
LOCUS RATFILAG 2312 bp ss-mRNA ROD 03-NOV-1990
DEFINITION Rat profilaggrin mRNA, 3' end.
ACCESSION M21759
KEYWORDS filaggrin; filament associated protein;
keratin filament aggregating protein; profilaggrin.
SOURCE Rat (strain Sprague-Dawley) newborn epidermis, cDNA to mRNA, clone
R4D6.
ORGANISM Rattus norvegicus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 2312)
AUTHORS Haydock,P.V. and Dale,B.A.
TITLE Filaggrin, an intermediate filament-associated protein: Structural
and functional implications from the sequence of a cDNA from rat
JOURNAL DNA Cell Biol. 9, 251-261 (1990)
STANDARD full staff_review
COMMENT Draft entry and computer-readable sequence kindly submitted by
P.Haydock, 04-JAN-1989.
FEATURES from to/span description
mRNA < 1 2311 profilaggrin mRNA
pept < 1 1878 profilaggrin (AA at 1)
matp 1 1218 filaggrin
BASE COUNT 585 a 691 c 657 g 379 t
ORIGIN 246 bp upstream of PstI site.
1 agcagtgcca gtgagggtcc ggggccccag agggaggctg ccagggacag ctctgagcag
61 gcccagtcca gaaggaccga gaccatcagc cgtggacgct caggacactc cactgggaga
121 gcccacgaag accgccacga gcaggcaaca gaccggtctg ccggctccgg gtccagggga
181 ggccaggccg gctcccacag tgagagcgag gcctccggtg gtcaggccgg ccgcagaggc
241 actgcagcca ccaggcacac atctcgcccc gaacagtctc cagacactgc tggccggacc
301 ggatccagcc gtggacagca gtccgcccaa cgacatggtg actcaacccc gggcagcaca
361 agaaccggct ccagaggaag aggagagtcc ccagctggcc agcagtcccc cgacagagcc
421 aggcacatcg aatccaggag gggtagaacc cgggaggcca gcgccagcca gtccagtgac
481 agcgaaggcc attctggagc ccatgccggg atcgggcaag ggcagacctc aaccattcac
541 aggagggcag gctccagctc agggagccag cgggcctctg ctggtggcca agcagctgac
601 acctccagtc gctcaggggc cagtcaaggc caggcatcag gccagggtcg tgcagggtcc
661 cgaagcaggg aagctcaggg catcgctcgt catgggcagt cgacagacag ccacaggcac
721 tctggggccg ggcaagcaca agcccacaca gccacaagca ttgacagcag gaggcctcgc
781 gggtccagcg agagtcaggc cagcgacagc gagggccact ccgactactc agaagcacac
841 acacagggag cccacggtgg gatccaaaca agccagaggc acgagcagcg accctcccga
901 ggccagcagg gctccggaca cccccaggtg tactactatg gtgtagaaga aaccgaggac
961 gagtccgatg cccagcaggg gcaccagcag cagcagcagc agcagcggca gcagcagcgg
1021 cagcggcagc agcacgaaca agaacgagaa catgaacagc agcagccaga gtccagccag
1081 aggcagcagg ggtccagtgg gagaacgcaa cgtgcagctc gccatgaaca ggatagcgac
1141 agcaccaggc aacggggctc tcaccaggcg cacagctccg ctcgcaccca ggaggagatc
1201 gcacgcggaa ggtctggagc cactgcaagt gagggtccgg ggccccagag ggaggctgcc
1261 agggacagct ctgagcacgc ccagtccaga aggaccgaga ccagcagccg tggacgctca
1321 ggacactcca ctgggagagc ccacgaagac cgccaccagc aggcaacaga ccgctctgcc
1381 cgctccgggt ccaggggagg ccaggccggc tcccacagtg agagcgaggc ctccggtggt
1441 caggccggcc gcagaggcac tgcagccacc aggcacacat ctcgccccga acagtctcca
1501 gacactgctg gccggaccgg atccagccgt ggacagcagt ccgcccaacg acatggtgac
1561 tcaaccccgg gcagcacaag aaccggctcc agaggaagag gagagtcccc agctggccag
1621 cagtcccccg acagagccag gcacatcgaa tccaggaggg gtagaacccg ggaggccagc
1681 gccagccagt ccagtgacag cgaaggccat tctggagccc atgccgggat cgggcaaggg
1741 cagacctcaa ccactcacag gagggcaggc tccagctcag ggagccagca ggcctctgtt
1801 gaaggttctg atggctatga ttctgttgtt aaatctaaat atcttagttt tagtcaatca
1861 tattgctatt attattaaca atgagagcag tttgcaacaa ttaattgctg aaatataacc
1921 tcacataggg attgttcatt ttagtatttg ggtttttggt tccttattct ccttaattca
1981 tatcaggtat ttccttttcc tttatagttc ctttactcta tcatattttg agcctaaatc
2041 gcttaggatc aggaatttaa attttaaact catcttgttt cctatcacag ttctttcttt
2101 cgtctttaaa atgtttaaat tggttcactg aagactagac acaattttac ccaaaaattt
2161 taaaatactc aaaaatttat aatgagtctt ttgtatgcat aatgccctgc ctgcactatg
2221 aatttatcat gtctatcctt tgtactttct tcttcactca ttctttccca ttggacattt
2281 ctgataaacc aaattaaaat tgtctaataa at
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