GenBank-Updates@genbank.bio.net (11/06/90)
LOCUS HUMIGHWMA 1290 bp ds-DNA PRI 06-NOV-1990
DEFINITION Human Ig germline H-chain D-region Dxp1 and Dxp'1 genes, 3' end.
ACCESSION M37485
KEYWORDS diversity exon; germline; immunoglobin heavy chain.
SOURCE Human fetal liver germline DNA, library of T. Maniatis, clone D12.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 1290)
AUTHORS Huang,C. and Stollar,B.David.
TITLE Analysis of members of the Dxp family of human immunoglobulin
diversity gene segments
JOURNAL Unpublished (1990)Tufts Health ,136 Harrison Ave, Boston, MA 02111
STANDARD full staff_review
COMMENT Draft entry and computer-readable sequence for [Unpublished (1990)
Tufts Univ Health Sci Campus, 136 Harrison Ave ,Boston, MA 02]
kindly submitted by B.D.Stollar, 03-AUG-1990.
FEATURES from to/span description
pept / 983 1012 Ig Dxp1 heavy-chain gene
pept / 1166 1195 Ig Dxp'1 heavy-chain gene
signal 954 963 nonamer recognition sequence
signal 976 982 heptamer recognition sequence
signal 1014 1020 heptamer recogntion sequence
signal 1033 1041 heptamer recognition sequence
signal 1137 1145 nonamer recognition sequence
signal 1159 1165 heptamer recognition sequence
signal 1197 1203 heptamer recognition sequence
signal 1216 1224 nonamer recognition sequence
BASE COUNT 269 a 401 c 371 g 249 t
ORIGIN Chromosome 14.
1 cccggacagg ttgcaggctc actgtgcagc agggcaggcg ggtacctgct ggcagttcct
61 ggggcctgat gtggagcaag cgcagggcca tatatcccgg aggacggcac agtcagtgaa
121 ttccagagag aagcaactca gccacactcc ccaggcagag ccgagaggac gtcccacgca
181 cagggaggca gagccagcac ctccgcagcc agcaccacct gtgcacgggc caccaccttg
241 caggcacaga gtgggtgctg agaggagggg cagggacacc aggcagggtg agcacccaga
301 gaaaactgca gacgcctcac acatccacct cagcctcccc tgacctggac ctcactggcc
361 tgggctcact taacctgggc ttcacctgac cttggcctca cctgacttgg acctcgcctg
421 tccaagcttt acctgacctg ggcctcacct gacctggacc tcatctggcc tggacctcac
481 ctggcctgga cttcacctgg cctgggcttc acctgacctg gacctcacct ggcctcgggc
541 tcacctgcac ctgctccagg tcttgctgga gcctgagtag cactgagggt gcagaagctc
601 atccagggtt ggggaatgac tctagaagtc tcccacatct gacctttctg ggtggaggca
661 gctggtggcc ctgggaatat aaaaatctcc agaatgatga ctctgtgatt tgtgggcaac
721 ttatgaaccc gaaaggacat ggccatgggg tgggtaggga catagggaca gatgccagcc
781 tgaggtggag cctcaggaca caggtgggca cggacactat ccacataagc gagggataga
841 cccgagtgtc cccacagcag acctgagagc gctgggccca cagcctcccc tcagagccct
901 gctgcctcct ccggtcagcc ctggacatcc caggtttccc caggcctgcc ggtaggttta
961 gaatgaggtc tgtgtcactg tggtattacg atattttgac tggttattat aaccacagtg
1021 tcacagagtc catcaaaaac ccatgcctgg aagcttcccg ccacagccct cccatggggc
1081 cctgctgcct cctcaggtca gccccggaca tcccgggttt ccccaggctg ggcggtaggt
1141 ttggggtgag gtctgtgtca ctgtggtatt actatggttc ggggagttat tataaccaca
1201 gtgtcacaga gtccatcaaa aacccatccc tgggagcctc ccgccacagc cctccctgca
1261 ggggaccggt acgtgccatg ttaggatttt
//