GenBank-Updates@genbank.bio.net (11/20/90)
LOCUS HUMGLI3A 5055 bp ss-mRNA PRI 20-NOV-1990
DEFINITION Human DNA-binding protein (GLI3) mRNA, complete cds.
ACCESSION M57609 M34366
KEYWORDS GLI3.
SOURCE Human glioblastoma multiforme xenograft D245MG, cDNA to mRNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 5055)
AUTHORS Ruppert,J., Michael Vogelstein,B., Arheden,K. and Kinzler,K.W.
TITLE GLI3 encodes a 190-kilodalton protein with multiple regions of GLI
similarity
JOURNAL Mol. Cell. Biol. 10, 5408-5415 (1990)
STANDARD simple staff_review
FEATURES from to/span description
pept 55 4845 DNA-binding protein (GLI3)
mRNA 1 5046 DNA-binding protein (GLI3) mRNA
BASE COUNT 1243 a 1591 c 1290 g 931 t
ORIGIN Chromosome 7p13.
1 cgatactacg tgggcatttt tggtcgaaga gagctgaagt aatgagaaga catcatggag
61 gcccagtccc acagctccac gaccactgaa aagaaaaaag ttgagaattc catagtgaag
121 tgctccactc gaacagatgt gagcgagaaa gccgttgcct ccagcaccac ttctaatgag
181 gatgaaagtc ctggacagac ttatcacaga gagagaagaa acgcaatcac tatgcagcca
241 cagaatgtcc aggggctcag caaagtcagt gaggaacctt caacatcgag tgacgagagg
301 gcctcattga tcaagaaaga gatccatggg tccctgccac acgtggcgga gccctctgtg
361 ccgtaccgcg ggacggtgtt tgccatggac cccaggaatg gttacatgga gccccactac
421 caccctcctc atcttttccc tgccttccat cctcctgtac caattgatgc cagacatcat
481 gagggccgtt accattacga tccatctccg attcctccat tgcatatgac ttccgcctta
541 tctagtagcc ctacgtatcc ggacctgccc ttcattagga tctccccaca ccggaacccc
601 gctgctgctt ccgagtctcc cttcagccct ccacatccct acattaatcc ctacatggac
661 tatatccgct ccttgcacag cagcccatcg ctctccatga tctcagcaac ccgtgggctg
721 agccctacag atgcgcccca tgcaggagtc agcccagcag aatactatca tcagatggcc
781 ctgctaactg gccagcgcag cccctatgca gacattattc cctcagctgc caccgccggc
841 acgggggcca tccacatgga atatcttcat gctatggata gcaccagatt ctccagcccc
901 aggctgtcag ccaggccgag ccgaaaacgt acactgtcca tatcaccact ctccgatcat
961 agctttgacc ttcagaccat gataaggacg tctcccaact ccttggtcac gattctcaat
1021 aattcccgta gcagctcttc agcaagtggc tcctatggtc acttatctgc aagtgcaatc
1081 agccctgcct tgagcttcac ctactcttcc gcgcccgtct ctctccacat gcatcagcag
1141 atcctaagcc gacaacagag cttaggttca gcctttggac acagccctcc actcatccac
1201 cctgccccaa cttttccaac acagaggcct attccaggga tccctacggt tctgaacccc
1261 gtccaggtca gctccggccc ttctgagtcc tcacagaaca agcccacgag tgagtctgca
1321 gtgagcagca ctggtgaccc gatgcacaac aagaggtcca agatcaaacc cgatgaagac
1381 ctccccagcc caggggctcg ggggcagcag gaacagcccg aaggaacaac ccttgtcaag
1441 gaggaagggg acaaagatga aagcaaacag gagcctgaag tcatctatga gacaaactgc
1501 cactgggaag gctgcgcgag ggagttcgac acccaagagc agcttgtgca ccatataaat
1561 aacgaccata ttcatggaga gaagaaggag ttcgtgtgca ggtggctgga ctgctcaaga
1621 gagcagaaac ccttcaaagc ccagtatatg ttggtagtgc atatgagaag acacacgggc
1681 gagaagcctc acaaatgcac ttttgaaggt tgcacaaagg cctactcgag actagaaaac
1741 ttgaaaacac acttgagatc tcacactgga gagaaaccat acgtctgtga gcacgaaggt
1801 tgcaacaagg ctttctcaaa tgcctctgat cgcgccaaac accaaaacag aacgcattcc
1861 aatgagaaac catatgtgtg caaaatccca ggctgcacta agcgttacac agacccaagc
1921 tccctccgga aacatgtgaa gacagtgcat ggcccagagg ctcatgtcac caagaagcag
1981 cgaggggaca tccatcctcg gccgccaccc ccgagagatt ccggcagcca ttcacagtcc
2041 aggtcgcctg gccgaccgac tcagggagcc cttggtgagc agcaggacct cagcaacact
2101 acctcaaagc gggaagaatg cctccaggtg aaaaccgtca aggcagagaa gccaatgaca
2161 tctcagccaa gccctggtgg tcagtcttca tgcagcagcc aacagtcccc catcagcaac
2221 tattccaaca gtgggctcga gcttcctctg accgatggag gtagtatagg agacctcagt
2281 gccatcgatg aaaccccaat catggactca accatttcca ctgcaaccac agcccttgct
2341 ttgcaagcca ggagaaaccc ggcagggacc aaatggatgg agcacgtaaa actagaaagg
2401 ctaaaacaag tgaatggaat gtttccgcga ctgaacccca ttctaccccc taaagcccct
2461 gcggtctctc ctctcatagg aaatggcaca cagtccaaca acacctgcag cttgggtggg
2521 cccatgacgc ttctcccggg cagaagcgac ctctctgggg tggacgtcac tatgctgaac
2581 atgctcaaca gaagggacag cagcgccagc accatcagct cggcctacct gagcagccgc
2641 cgctcctcag ggatctcgcc ctgcttctcc agccgccgct ccagcgaggc gtcacaggcc
2701 gagggccggc cgcagaacgt gagcgtggcc gactcctacg accccatctc caccgacgcc
2761 tcgcgccgct ccagcgaagc cagccagagc gacggcctgc ccagcctgct cagcctcacg
2821 cccgcccagc agtaccgcct caaggccaag tacgcggctg ccacaggagg gccgccgccg
2881 acgcccctgc ccaacatgga gaggatgagc ctgaagacgc gcctggcgct gctcggggat
2941 gccctcgagc ctggcgtggc cctgcctcca gttcatgccc cgaggaggtg cagcgacggg
3001 ggagcccacg gctacgggcg gcgccacctg cagccgcacg atgcgctggg ccacggcgtg
3061 aggagggcca gcgacccggt gcggacaggc tccgagggcc tggccctgcc tcgtgtgccg
3121 cgcttcagca gcctcagcag ctgcaacccc ccggcgatgg ccacgtccgc ggagaagcgc
3181 agtctcgtgc ttcagaatta cacgcggccc gagggcggcc agtcccgaaa cttccactcg
3241 tccccctgtc ctcccagcat caccgagaac gtcaccctgg agtccctgac catggacgct
3301 gatgccaacc tgaacgatga ggatttcctg ccggacgacg tggtgcagta tttaaattcc
3361 cagaaccaag cagggtacga gcagcacttc cccagcgccc tcccggacga cagcaaagtg
3421 ccccacgggc ccggtgactt tgacgcgccc gggctgccag acagccacgc tggccagcag
3481 ttccatgccc tcgagcagcc ctgccccgag ggcagcaaaa ccgacctgcc cattcagtgg
3541 aacgaagtca gctccggaag cgccgacctg tcctcctcca agctcaagtg tgggccgcgg
3601 cccgctgtgc cgcagactcg cgcctttggg ttctgcaacg gcatggtcgt ccacccgcag
3661 aaccccttga ggagcgggcc tgctgggggc tatcagaccc tcggggagaa cagcaacccc
3721 tacggtggcc cagagcactt gatgctccac aacagccccg gaagtggcac cagtggaaac
3781 gccttccatg aacagccctg taaggccccg cagtatggga actgtctcaa caggcagcca
3841 gtggcccctg gtgcactcga cggtgcctgt ggtgccggga ttcaagcctc aaagctgaag
3901 agcaccccca tgcaagggag cgggggccag ctgaatttcg gcctgccggt agcgccaaat
3961 gagtcagctg gcagcatggt gaatggcatg cagaaccagg acccagtggg acaggggtac
4021 ctggctcacc agctcctcgg cgacagcatg cagcacccgg gggcaggccg ccccggtcag
4081 cagatgcttg ggcagattag tgctacctca cacatcaaca tctaccaagg gccagagagc
4141 tgcctgccag gggctcacgg catgggcagc cagccgtcaa gcttggcagt tgtcaggggc
4201 taccagccat gtgccagctt tgggggcagc aggcgccagg ctatgccgag ggacagcctt
4261 gctctgcagt caggacagct cagtgacaca agtcagacct gcagggtgaa tggtatcaag
4321 atggagatga aagggcagcc ccatccgctg tgctctaatc tgcagaatta ctctggtcag
4381 ttctatgacc aaaccgtggg cttcagtcag caagacacga aagctggttc attctctatt
4441 tcagacgcca gctgcctgct acaggggacc agcgccaaaa actctgagtt actttcccca
4501 ggtgctaatc aggtgacaag cacagtggac agcctcgaca gccatgacct ggaaggggta
4561 cagattgact tcgatgccat catagacgat ggggaccact ccagcctgat gtcgggggcc
4621 ctgagcccaa gtatcattca gaacctttcc catagctcct cccgcctcac cacgcctcgg
4681 gcgtccctcc cattcccagt cgctgtccat gagcaccacc aacatggcta tcggggacat
4741 gagttctttg ctgacctccc tagcggaaga aagcaaattc cttgcagtta tgcaataggc
4801 tttaggaaaa aaagactgca accaacggaa atcaatagga gttgaagaga ttaaactgac
4861 tttgttttgg ctgttttttt agttctgtat gtattttagc aatctcatct cacctaactg
4921 agatgtgttt caattatatt ccttttatgg aaaaggactc tgaaaaaccc taaagtattc
4981 tagggagaaa ctgtcttcca tttcagtttt gaatcagtat tgttacactc aaaccaccct
5041 ctttttaaaa aaaaa
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