GenBank-Updates@genbank.bio.net (12/22/90)
LOCUS MUSIGVH36 417 bp ds-DNA VRT 22-DEC-1990
DEFINITION Mouse IgM germline chain gene V-region (VH36-65).
ACCESSION M57241
KEYWORDS germline; immunoglobulin; immunoglobulin heavy chain;
mu-immunoglobulin; variable region.
SOURCE Mouse (strain C57BL/6J) kidney DNA.
ORGANISM Mus musculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 417)
AUTHORS Gerstein,R.M., Frankel,W.N., Hsieh,C.-L., Durdik,J.M., Rath,S.,
Coffin,J.M., Nisonoff,A. and Selsing,E.
TITLE Isotype switching of an immunoglobulin heavy chain transgene occurs
by DNA recombination between different chromosomes
JOURNAL Cell 63, 537-548 (1990)
STANDARD full staff_entry
FEATURES Location/Qualifiers
sig_peptide join(1..47,131..141)
/gene="IgM"
/codon_start=2
CDS join(1..47,131..141,142..>417)
/gene="IgM"
/codon_start=2
/partial
/product="immunoglobulin mu chain"
mat_peptide 142..>417
/gene="IgM"
/codon_start=142
/product="immunoglobulin mu chain"
BASE COUNT 107 a 98 c 105 g 107 t
ORIGIN Chromosome 12
1 catggaattg atctgggtct ttctcttcct cctgtcagta actgcaggta aggggctcac
61 catttccaaa tctgaagtag agaaatggcc tgggatgtca ctcaaatcca ctctgtcttt
121 ctcttcacag gtgtccactc tgaggttcag cttcagcagt ctggagctga gctggtgagg
181 cctgggtcct cagtgaagat gtcctgcaag acttctggat atacattcac aagctacggt
241 ataaactggg tgaagcagag gcctggacag ggcctggaat ggattggata tatttatatt
301 ggaaatggtt atactggata caatgagaag ttcaagggca aggccacact gacttcagac
361 acatcctcca gcacagccta catgcagctc agcagcctga catctgagga ctctgca
//