GenBank-Updates@genbank.bio.net (01/10/91)
LOCUS RABIGHVDJC 1300 bp ds-DNA MAM 10-JAN-1991
DEFINITION Rabbit rearranged Ig heavy chain gene VDJ-region, clone MLN-a3.
ACCESSION M55383
KEYWORDS diversity exon; immunoglobulin heavy chain; joining exon;
processed gene; variable region.
SOURCE Rabbit adult spleen DNA, clone MLN-a3.
ORGANISM Oryctolagus cuniculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Lagomorpha; Leporidae.
REFERENCE 1 (bases 1 to 1300)
AUTHORS Becker,R.S. and Knight,K.L.
TITLE Somatic diversification of immunoglobulin heavy chain VDJ genes:
Evidence for somatic gene conversion in rabbits
JOURNAL Cell 63, 987-997 (1990)
STANDARD full staff_review
FEATURES Location/Qualifiers
sig_peptide join(787..832,935..945)
/gene="IgH"
CDS join(787..832,935..1300)
/gene="IgH"
/partial
/product="Ig heavy chain"
intron 833..934
/gene="IgH"
exon 935..1300
/number=2
/gene="IgH"
/codon_start=935
/partial
mat_peptide 946..1300
/gene="IgH"
/codon_start=946
/partial
/product="Ig heavy chain"
BASE COUNT 326 a 337 c 314 g 323 t
ORIGIN
1 tcggtaccca accttaaaaa atccatttgc aggccttcat ctgtttaaaa gtgggtgaca
61 ggcattagga caaaataggc tataagttct actaggggca cccctgttct catcagagaa
121 attactgagt gtatcctcat ggcttcccac attttccctc acaatgtatc atgggaaact
181 gtagatgacg ctacacatga atgaaccctt acccctgagg ttggaaatac agacagagtt
241 tcttgctccc gggttcagaa agactaactc ctagatgtca taggcatttg ggatgtctgg
301 ggctgtcact caaaggcaga tatctcctat tgtcaacttt tctgtccatc tctacatttc
361 tgtattctct cctcttcatc tatcactgtc ccaatgtctt tcatatagat gataaggaac
421 caatggttat ttaaataaat gggggacatg atattgctaa ctctggatat taagggtaca
481 cacatattag aatgaagcaa ggtatttgcc ttcaactttt taaaataatg gtaacataaa
541 aattcatatg atctgaatcc tatcacagcc atcactctac atacccagga caccacatct
601 gccctgggcc ctctcctgtc tgaggcgtct acctcatgcc tgctatatag gggcagcaca
661 tgcaaatagg gcctccctct gccctgaaaa ccagcccagc cctcaccctg cagctctggc
721 acaggagctc cagccccagc actcccaggt gtccaccagt gatcgcactc aacacagaca
781 ctcaccatgg agactgggct gcgctggctt ctcctggtcg ctgtgctcaa aggtaatgat
841 ggagaacgcg gggcactgag tctgggagag gacgtgagtg agagacacag acagtgtgag
901 tgacagtacc tgaccatgtc gtctgtgttt gcaggtgtcc agtgtcaggc gttggaggag
961 tccgggggag acctggtcaa gcctggggca tccctgacac tcacctgcaa agcctctgga
1021 ttctccttca gtagcggcta ctacatgtgc tgggtccgcc aggctccagg gaaggggctg
1081 gagtggatcg catgcattga tgttggtagt agtgttagca cttactacgc gagctgggcg
1141 aaaggccgat tcaccatcac cagaagcacc agcctgaaca cggtgactct gcaactgaac
1201 agtctgacag ccgcggacac ggccacctat ttctgtgcga gaggttatgc tggtagtagt
1261 caagccttta acttgtgggg cccaggcacc ctggtcacgg
//