GenBank-Updates@genbank.bio.net (01/10/91)
LOCUS RABIGHVDJG 734 bp ds-DNA MAM 10-JAN-1991
DEFINITION Rabbit rearranged Ig heavy chain gene VDJ-region, clone PCR4-7.
ACCESSION M55387
KEYWORDS diversity exon; immunoglobulin heavy chain; joining exon;
processed gene; variable region.
SOURCE Rabbit spleen DNA, clone PCR4-7.
ORGANISM Oryctolagus cuniculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Lagomorpha; Leporidae.
REFERENCE 1 (bases 1 to 734)
AUTHORS Becker,R.S. and Knight,K.L.
TITLE Somatic diversification of immunoglobulin heavy chain VDJ genes:
Evidence for somatic gene conversion in rabbits
JOURNAL Cell 63, 987-997 (1990)
STANDARD full staff_review
FEATURES Location/Qualifiers
sig_peptide join(236..281,384..394)
/gene="IgH"
CDS join(236..281,384..734)
/gene="IgH"
/partial
/product="Ig heavy chain"
misc_feature 1..29
/note="5' PCR primer"
exon 384..734
/number=2
/gene="IgH"
/partial
mat_peptide 395..734
/gene="IgH"
/codon_start=395
/partial
/product="Ig heavy chain"
misc_feature 710..734
/note="3' PCR primer"
BASE COUNT 161 a 225 c 199 g 149 t
ORIGIN
1 gaattcctat cacagccatc actctacata cccaggacac cacatctgcc ctgggccctc
61 tcctgtctga ggcgtctacc tcatgcctgc tatatagggg cagcacatgc aaatagggcc
121 tccctctgcc catgaaaacc agcccagccc tcaccctgca gctctggcac aggagctcca
181 gccccagcac tcccaggtgt ccactcagtg atcgcactca acacagacac tcaccatgga
241 gactgggctg cgctggcttc tcctggtcgc tgtgctcaaa ggtaatgatg gggaacgcgg
301 ggcactgagt ctgggagagg acgtgagtga gagacacaga cagtgtgagt gacagtacct
361 gaccatgtcg tctgtgtttg caggtgtcca gtgtcagtcg ttggaggagt ccgggggaga
421 cctggtcaag cctggggcat ccctgacact cacctgcaca gcctctagat tctccttcag
481 tagcagctac tacatgtgct gggtccgcca ggctccaggg aagaggcctg agtggatcgc
541 atgcatgtat gctgatagta gtggtagcac ttactacgcg agctgggcga aaggccgatt
601 caccatctcc aaaacctcgt cgaccacggt gacgctgcaa atgagcagtc tgacagtcgc
661 ggacacggcc acctatttct gtacgaagac cctaaacttg tggggcccag gcaccctggt
721 caccgtctcc tcag
//