GenBank-Updates@genbank.bio.net (01/10/91)
LOCUS RABIGHVDJH 1096 bp ds-DNA MAM 10-JAN-1991
DEFINITION Rabbit rearranged Ig heavy chain gene VDJ-region, clone Ph1-1-a3.
ACCESSION M55388
KEYWORDS diversity exon; immunoglobulin heavy chain; joining exon;
processed gene; variable region.
SOURCE Rabbit spleen and mesenteric lymph node DNA, clone Ph1-1-a3.
ORGANISM Oryctolagus cuniculus
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Lagomorpha; Leporidae.
REFERENCE 1 (bases 1 to 1096)
AUTHORS Becker,R.S. and Knight,K.L.
TITLE Somatic diversification of immunoglobulin heavy chain VDJ genes:
Evidence for somatic gene conversion in rabbits
JOURNAL Cell 63, 987-997 (1990)
STANDARD full staff_review
FEATURES Location/Qualifiers
sig_peptide join(514..559,663..673)
/gene="IgH"
CDS join(514..559,663..1096)
/pseudo=493-494
/gene="IgH"
/partial
/product="Ig heavy chain"
exon 663..1096
/number=2
/gene="IgH"
/codon_start=663
/partial
mat_peptide 674..1096
/pseudo=1079-1081
/gene="IgH"
/codon_start=674
/partial
/product="Ig heavy chain"
BASE COUNT 254 a 298 c 265 g 279 t
ORIGIN
1 gatgtcatag gcatttggga tgtctggggc tgtcactcaa aggcagatat ctcctattgt
61 caacttttct gtccatctct acatttctgt attctctcct cttcatctat cactgtccca
121 atgtctttca tatagatgat aaggaaccaa tggttattta aataaatggg ggacatgata
181 ttgctaactc tggatattaa gggtacacac atattagaat gaagcaaggt atttgccttc
241 aactttttaa aataatggta acataaaaat tcatatgatc tgaatcctat cacagccatc
301 actctacata cccaggacac cacatctgcc ctgggccctc tcctgtctga ggcgtctacc
361 tcatgcctgc tatatagggg cagcacatgc aaatagggcc tccctctgcc ctgaaaacca
421 gcccagccct caccctgcag ctctggcaca ggagctccag ccccagcact cccaggtgtc
481 caccagtgat cgcactcaac acagacactc accatggaga ctgggctgcg ctggcttctc
541 ctggtcgctg tgctcaaagg taatgatgga gaacgcgggg cactgagtct gggagaggac
601 gtgagtgaga gacccagaga gtgtgagtga cagcttcctg accatgtctt ctgtgtttgc
661 aggtgtccag tgtcaggagc agctggtgga gtccggggga ggcctggtcc agcctgaggg
721 atccctgaca ctcacctgca cagcctctgg attctccttc agtagcagct actggatatg
781 ctgggtccgc caggctccag ggaaggggct ggagtggatc gcatgcattt atggtggtag
841 tggtggttac acttactacg cgacctgggc gaaaggccga ttaaccatct ccaaaacctc
901 gtcgaccacg gtgactctgc aaatgaccag tctgacggcc gcggacacgg ccacctattt
961 ctgtgccaga ccatatacga gtggtactac ttattatcat tttaacttgt ggggcccagg
1021 caccctggtc accgtctcct caggtgagtc cttgccaact ctctctccta ctcaactctg
1081 agcgattttt ctgcag
//