GenBank-Updates@genbank.bio.net (01/10/91)
LOCUS HUMGMP1417 619 bp ds-DNA PRI 10-JAN-1991
DEFINITION Human granule membrane protein-140 gene, exon 17.
ACCESSION M60235
KEYWORDS granule membrane protein 140; leukocyte adhesion receptor;
selectin.
SEGMENT 17 of 17
SOURCE Human DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (sites)
AUTHORS Johnston,G.I., Cook,R.G. and McEver,R.P.
TITLE Cloning of GMP-140, a granule membrane protein of platelets and
endothelium: Sequence similarity to proteins involved in cell
adhesion and inflammation
JOURNAL Cell 56, 1033-1044 (1989)
STANDARD full staff_review
REFERENCE 2 (bases 1 to 619)
AUTHORS Johnson,G.I., Bliss,G.A., Newman,P.J. and McEver,R.P.
TITLE Structure of the human gene encoding granule membrane protein-140,
a member of the selectin family of adhesion receptors for
leukocytes
JOURNAL J. Biol. Chem. 265, 21381-21385 (1990)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
intron (M60234:66..75,1..9)
/number=17
/gene="GMP-140"
mRNA join(M60217:1..41,M60218:10..100,
M60219:10..396,M60222:10..117,M60223:10..195,
M60224:10..195,M60225:10..195,M60226:10..195,
M60227:10..195,M60228:10..195,M60229:10..195,
M60230:10..219,M60231:10..195,M60232:10..129,
M60233:10..40,M60234:10..65,10..619)
/gene="GMP-140"
/partial
/product="granule membrane protein-140"
exon 10..619
/number=17
/gene="GMP-140"
/codon_start=10
BASE COUNT 166 a 160 c 128 g 165 t
ORIGIN
1 ttgctgcagg tttccataaa cacccatgaa tcaaagacat ggaattacct tagattagct
61 ctggaccagc ctgttggacc cgctctggac caaccctgtt tcctgagttt gggattgtgg
121 tacaatctca aattctcaac ctaccacccc ttcctgtccc acctcttctc ttcctgtaac
181 acaagccaca gaagccagga gcaaatgttt ctgcagtagt ctctgtgctt tgactcacct
241 gttacttgaa ataccagtga accaaagaga ctggagcatc tgactcacaa gaagaccaga
301 ctgtggagaa ataaaaatac ctctttattt tttgattgaa ggaaggtttt ctccactttg
361 ttggaaagca ggtggcatct ctaattggaa gaaattcctg tagcatcttc tggagtctcc
421 agtggttgct gttgatgagg cctcttggac ctctgctctg aggcttccag agagtcctct
481 ggatggcacc agaggctgca gaaggccaag aatcaagcta gaaggccaca tgtcaccgtg
541 gaccttcctg ccaccagtca ctgtccctca aatgacccaa agaccaatat tcaaatgcgt
601 aattaaaaga attttcccc
//