GenBank-Updates@genbank.bio.net (01/12/91)
LOCUS HUMLCK5PA 679 bp ds-DNA PRI 12-JAN-1991
DEFINITION Human lck gene, 5' promoter region.
ACCESSION M36824
KEYWORDS lck protein; tyrosine kinase.
SOURCE Human adult female peripheral blood leukocyte DNA, clone sp12.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 679)
AUTHORS Wildin,R.S., Garvin,A.M., Pawar,S., Lewis,D.B., Abraham,K.M.,
Forbush,K.A. and Perlmutter,R.M.
TITLE Developmental regulation of lck gene expression in T lymphocytes
JOURNAL J. Exp. Med. (1991) In press
STANDARD full staff_entry
COMMENT Draft entry and computer-readable sequence for [Unpublished (1990)
University of Washington, Medical Genetics,SL-15 Seattle, WA ]
kindly submitted
by R.S.Wildin, 20-JUL-1990.
Author address:
University of Washington
Medical Genetics,
SL-15 Seattle, WA 98195
wilddrb@u.washington.edu
FEATURES Location/Qualifiers
precursor_RNA 563..>679
/note="lck mRNA and introns"
misc_feature 563..670
/note="lck 1a untranslated exon"
BASE COUNT 132 a 176 c 230 g 141 t
ORIGIN Chromosome 1p35-p32.
1 tagcctgcca ttcacctacc cttggctata attaaagctt actggtccaa tgccctgagg
61 tggcatggga aatggtctct cggcctggcc tggctgtaac aatgcatggt ctgctcacca
121 gctatttaac agggatatgt cctctcctct gactctgacg atgctccttt gctgccaaga
181 cagaacaaag gtctctcagc tgcaacgtgt gctgagtgct gttgcctctc accataagct
241 gagtgtgtgt ccgcttgccc cctgctcact gggcccaaag gctgcccttg aatctcttgc
301 ccagatgcac cctggagggc agaagggagg gtctatcaga catcctcccc ctcaacttta
361 aacctcccag tgtcaccctg ggacagtagg ggaagatgga cctggtctgg agatgtaggg
421 gacccccagg ggctgagagg caggggtcta tggtggcagg aagcttggcg tgctagaggg
481 ttgtggttgg gctgctgggg cccggttggc tgcggagccc tccggaggag gcaggaagtc
541 agggtgggac gtgggcgcgg ggagacaggt ggtggctacg acggcgaagg gagctgagac
601 tgtccaggca gccaggttag gccaggagga ccatgtgaat ggggccagag ggctcccggg
661 ctgggcaggt aaggagcgc
//