GenBank-Updates@genbank.bio.net (09/29/90)
LOCUS HUMPAM12 3748 bp ss-mRNA PRI 28-SEP-1990
DEFINITION Human peptidylglycine alpha-amidating monooxygenase mRNA, complete
cds.
ACCESSION M37721
KEYWORDS peptidylglycine alpha-amidating monooxygenase.
SOURCE Human thyroid carcinoma, cDNA to mRNA, clones lambda-PAM[1-3].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3748)
AUTHORS Glauder,J., Ragg,H., Rauch,J. and Engels,J.W.
TITLE Human peptidylglycine alpha-amidating monooxygenase: cDNA, cloning
and functional expression of a truncated form in COS cells
JOURNAL Biochem. Biophys. Res. Commun. 169, 551-558 (1990)
STANDARD simple staff_entry
FEATURES from to/span description
pept 189 3113 peptidylglycine alpha-amidating monooxygenase
(EC 1.14.17.3)
variant 1857 1857 g could be c
variant 1108 1108 a could be c
variant 1109 1109 t could be g
variant 2564 2564 c could be t
BASE COUNT 1038 a 797 c 881 g 1032 t
ORIGIN
1 cggaccgaga cgcctcgccg cggccagctc gctgctctcg ctggcggatg gtgtgtggcc
61 gccgcaggac gcccgccgtg cccgggccat gaagtagcgg ctgctggcgg cgccgctgcc
121 caaccgccag ccccagcccc gcgctgcgct gcccggtcct ctcccggcgg ggtcgtatcg
181 gcgtggacat ggctggccgc gtccctagcc tgctagttct ccttgttttt ccaagcagct
241 gtttggcttt ccgaagccca ctttctgtct ttaagaggtt taaagaaact accagaccat
301 tttccaatga atgtcttggt accaccagac ccgtagttcc tattgattca tcagattttg
361 cattggatat tcgcatgcct ggggttacac ctaaacagtc cgatacatac ttctgcatgt
421 ctatgcgaat accagtggat gaggaagcct tcgtgattga cttcaagcct cgagccagca
481 tggatactgt ccatcacatg ttactttttg gatgcaatat gccttcatcc actggaagtt
541 actggttttg tgatgaagga acctgtacag ataaagccaa tattctgtat gcctgggcga
601 gaaatgctcc ccctacccgg ctccccaaag gtgttggatt cagagttgga ggagagactg
661 gaagtaaata ctttgtacta caggtacact atggggatat tagtgctttt agagataata
721 acaaggactg ttctggtgtg tccttacacc tcacacgtct gccacagcct ttaattgctg
781 gcatgtacct tatgatgtct gttgacactg ttatcccagc aggagaaaaa gtggtgaatt
841 ctgacatttc atgccattat aaaaattatc caatgcatgt ctttgcctat agagttcaca
901 ctcaccattt aggtaaggta gtaagtggat acagagtaag aaatggacag tggacactga
961 ttggacggca gagccctcag ctgccacagg ctttctaccc tgtggggcat ccagttgatg
1021 taagttttgg tgacctactg gctgcaagat gtgtattcac tggtgaagga aggacagaag
1081 ccacacacat tggtggcacg tctagtgatg aaatgtgcaa cttatacatt atgtattaca
1141 tggaagccaa gcatgcagtt tctttcatga cctgtaccca gaatgtagct ccagatatgt
1201 tcagaaccat accaccagag gccaacattc caattcccgt gaagtctgat atggttatga
1261 tgcatgaaca tcataaagaa acagaatata aagataagat tcctttacta cagcagccaa
1321 aacgagaaga agaagaagtg ttagaccagg gtgatttcta ttcactactt tccaagctgc
1381 taggagaaag ggaagatgtt gttcatgtgc acaaatataa tcctacagaa aaggcagaat
1441 cagagtcaga cctggtagct gagattgcaa atgtagtcca aaaaaaggat cttggtcgat
1501 ctgatgccag agagggtgca gaacatgaga ggggtaatgc tattcttgtc agagacagaa
1561 ttcacaaatt ccacagacta gtatctacct tgaggccacc agagagcaga gttttctcat
1621 tacagcagcc cccacctggt gaaggcacct gggaaccaga acacacagga gatttccaca
1681 tggaagaggc actggattgg cctggagtat acttgttacc aggccaggtt tctggggtgg
1741 ctctagaccc taagaataac ctggtgattt tccacagagg tgaccatgtc tgggatggaa
1801 actcgtttga cagcaagttt gtttaccagc aaataggact cggaccaatt gaagaagaca
1861 ctattcttgt catagatcca aataatgctg cagtactcca gtccagtgaa aaaaatctgt
1921 tttacttgcc acatggcttg agtatagata aagatgggaa ttattgggtc acagacgtgg
1981 ctctccatca ggtgttcaaa ctggatccaa acaataaaga aggccctgta ttaatcctgg
2041 gaaggagcat gcaaccaggc agtgaccaga atcacttctg tcaacccact gatgtggctg
2101 tggatccagg cactggagcc atttatgtat cagatggtta ctgcaacagc aggattgtgc
2161 agttttcacc aagtggaaag ttcatcacac agtggggaga agagtcttca gggagcagtc
2221 ctctgccagg ccagttcact gttcctcaca gcttggctct tgtgcctctt ttgggccaat
2281 tatgtgtggc agaccgggaa aatggtcgga tccagtgttt taaaactgac accaaagaat
2341 ttgtgagaga gattaagcat tcatcatttg gaagaaatgt atttgcaatt tcatatatac
2401 caggcttgct ctttgcagtg aatgggaagc ctcattttgg ggaccaagaa cctgtacaag
2461 gatttgtgat gaacttttcc aatggggaaa ttatagacat cttcaagcca gtgcgcaagc
2521 actttgatat gcctcatgat attgttgcat ctgaagatgg gaccgtgtac attggagatg
2581 ctcataccaa caccgtgtgg aagttcacct tgactgagaa attggaacat cgatcagtta
2641 aaaaggctgg cattgaggtc caggaaatca aagaagccga ggcagttgtt gaaaccaaaa
2701 tggagaacaa acccacctcc tcagaattgc agaagatgca agagaaacag aagctgatca
2761 aagagccagg ctcgggagtg cctgttgttc tcattacaac ccttctggtt attccggtgg
2821 ttgtcctgct ggccattgcc atatttattc ggtggaaaaa atcaagggcc tttggagcag
2881 attctgaaca caaactcgag acgagttcag gaagagtact gggaagattt agaggaaagg
2941 gaagtggagg cttaaacctt ggtaatttct ttgcaagccg taagggctac agtcgaaaag
3001 ggtttgaccg gcttagcact gagggcagtg accaagagaa agaggatgat ggaagtgaat
3061 cagaagagga gtattcagca cctctgcctg cgctcgcacc ttcctcctcc tgaaaaccaa
3121 gctttgattt agattgagta agatttaccc agaatgtcag attcctttcc ctttagcacg
3181 tttaaagttc tgtgtattta attgtaaact gtactagtct gtgtgggact gtacacactt
3241 tatttacttc gttttggtta agttggcttc tgtttctagt tgaggagttt cctaaaagtt
3301 cataacagtg ccattgtctt tatatgaaca tagactagag aaaccgtcct ctttttccat
3361 cataattcta atctaacaat ggaagatttg cccatttaca cttttgagac tttttggtgg
3421 atgtaaataa ccccattctt tgcttgaaca cagtatcttc ccaatagcac tttcattgcc
3481 agtgtctttc tttggtgcct ttcctgttca gcattcttag cctgtggcaa taaagagaaa
3541 ctttgtgcta catgacgaca aagctgctaa atctcctatt tttttaaaat cactaacatt
3601 atattgcaat gaaggaaata aaaaagtctc tatttaaatt cttttttaaa ttttcttcag
3661 ttggtgtgtt tttgggatgt cttattttta gatggttaca ctgttagaac actattttca
3721 gaatctgaat gtaatttgtg taataacg
//GenBank-Updates@genbank.bio.net (01/12/91)
LOCUS HUMPAM12 3748 bp ss-mRNA PRI 12-JAN-1991
DEFINITION Human peptidylglycine alpha-amidating monooxygenase mRNA, complete
cds.
ACCESSION M37721
KEYWORDS peptidylglycine alpha-amidating monooxygenase.
SOURCE Human thyroid carcinoma, cDNA to mRNA, clones lambda-PAM[1-3].
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 3748)
AUTHORS Glauder,J., Ragg,H., Rauch,J. and Engels,J.W.
TITLE Human peptidylglycine alpha-amidating monooxygenase: cDNA, cloning
and functional expression of a truncated form in COS cells
JOURNAL Biochem. Biophys. Res. Commun. 169, 551-558 (1990)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
CDS 189..3113
/note="peptidylglycine alpha-amidating monooxygenase (EC
1.14.17.3)"
variation 1108..1108
/note="a could be c"
variation 1109..1109
/note="t could be g"
variation 1857..1857
/note="g could be c"
variation 2564..2564
/note="c could be t"
BASE COUNT 1038 a 797 c 881 g 1032 t
ORIGIN
1 cggaccgaga cgcctcgccg cggccagctc gctgctctcg ctggcggatg gtgtgtggcc
61 gccgcaggac gcccgccgtg cccgggccat gaagtagcgg ctgctggcgg cgccgctgcc
121 caaccgccag ccccagcccc gcgctgcgct gcccggtcct ctcccggcgg ggtcgtatcg
181 gcgtggacat ggctggccgc gtccctagcc tgctagttct ccttgttttt ccaagcagct
241 gtttggcttt ccgaagccca ctttctgtct ttaagaggtt taaagaaact accagaccat
301 tttccaatga atgtcttggt accaccagac ccgtagttcc tattgattca tcagattttg
361 cattggatat tcgcatgcct ggggttacac ctaaacagtc cgatacatac ttctgcatgt
421 ctatgcgaat accagtggat gaggaagcct tcgtgattga cttcaagcct cgagccagca
481 tggatactgt ccatcacatg ttactttttg gatgcaatat gccttcatcc actggaagtt
541 actggttttg tgatgaagga acctgtacag ataaagccaa tattctgtat gcctgggcga
601 gaaatgctcc ccctacccgg ctccccaaag gtgttggatt cagagttgga ggagagactg
661 gaagtaaata ctttgtacta caggtacact atggggatat tagtgctttt agagataata
721 acaaggactg ttctggtgtg tccttacacc tcacacgtct gccacagcct ttaattgctg
781 gcatgtacct tatgatgtct gttgacactg ttatcccagc aggagaaaaa gtggtgaatt
841 ctgacatttc atgccattat aaaaattatc caatgcatgt ctttgcctat agagttcaca
901 ctcaccattt aggtaaggta gtaagtggat acagagtaag aaatggacag tggacactga
961 ttggacggca gagccctcag ctgccacagg ctttctaccc tgtggggcat ccagttgatg
1021 taagttttgg tgacctactg gctgcaagat gtgtattcac tggtgaagga aggacagaag
1081 ccacacacat tggtggcacg tctagtgatg aaatgtgcaa cttatacatt atgtattaca
1141 tggaagccaa gcatgcagtt tctttcatga cctgtaccca gaatgtagct ccagatatgt
1201 tcagaaccat accaccagag gccaacattc caattcccgt gaagtctgat atggttatga
1261 tgcatgaaca tcataaagaa acagaatata aagataagat tcctttacta cagcagccaa
1321 aacgagaaga agaagaagtg ttagaccagg gtgatttcta ttcactactt tccaagctgc
1381 taggagaaag ggaagatgtt gttcatgtgc acaaatataa tcctacagaa aaggcagaat
1441 cagagtcaga cctggtagct gagattgcaa atgtagtcca aaaaaaggat cttggtcgat
1501 ctgatgccag agagggtgca gaacatgaga ggggtaatgc tattcttgtc agagacagaa
1561 ttcacaaatt ccacagacta gtatctacct tgaggccacc agagagcaga gttttctcat
1621 tacagcagcc cccacctggt gaaggcacct gggaaccaga acacacagga gatttccaca
1681 tggaagaggc actggattgg cctggagtat acttgttacc aggccaggtt tctggggtgg
1741 ctctagaccc taagaataac ctggtgattt tccacagagg tgaccatgtc tgggatggaa
1801 actcgtttga cagcaagttt gtttaccagc aaataggact cggaccaatt gaagaagaca
1861 ctattcttgt catagatcca aataatgctg cagtactcca gtccagtgaa aaaaatctgt
1921 tttacttgcc acatggcttg agtatagata aagatgggaa ttattgggtc acagacgtgg
1981 ctctccatca ggtgttcaaa ctggatccaa acaataaaga aggccctgta ttaatcctgg
2041 gaaggagcat gcaaccaggc agtgaccaga atcacttctg tcaacccact gatgtggctg
2101 tggatccagg cactggagcc atttatgtat cagatggtta ctgcaacagc aggattgtgc
2161 agttttcacc aagtggaaag ttcatcacac agtggggaga agagtcttca gggagcagtc
2221 ctctgccagg ccagttcact gttcctcaca gcttggctct tgtgcctctt ttgggccaat
2281 tatgtgtggc agaccgggaa aatggtcgga tccagtgttt taaaactgac accaaagaat
2341 ttgtgagaga gattaagcat tcatcatttg gaagaaatgt atttgcaatt tcatatatac
2401 caggcttgct ctttgcagtg aatgggaagc ctcattttgg ggaccaagaa cctgtacaag
2461 gatttgtgat gaacttttcc aatggggaaa ttatagacat cttcaagcca gtgcgcaagc
2521 actttgatat gcctcatgat attgttgcat ctgaagatgg gaccgtgtac attggagatg
2581 ctcataccaa caccgtgtgg aagttcacct tgactgagaa attggaacat cgatcagtta
2641 aaaaggctgg cattgaggtc caggaaatca aagaagccga ggcagttgtt gaaaccaaaa
2701 tggagaacaa acccacctcc tcagaattgc agaagatgca agagaaacag aagctgatca
2761 aagagccagg ctcgggagtg cctgttgttc tcattacaac ccttctggtt attccggtgg
2821 ttgtcctgct ggccattgcc atatttattc ggtggaaaaa atcaagggcc tttggagcag
2881 attctgaaca caaactcgag acgagttcag gaagagtact gggaagattt agaggaaagg
2941 gaagtggagg cttaaacctt ggtaatttct ttgcaagccg taagggctac agtcgaaaag
3001 ggtttgaccg gcttagcact gagggcagtg accaagagaa agaggatgat ggaagtgaat
3061 cagaagagga gtattcagca cctctgcctg cgctcgcacc ttcctcctcc tgaaaaccaa
3121 gctttgattt agattgagta agatttaccc agaatgtcag attcctttcc ctttagcacg
3181 tttaaagttc tgtgtattta attgtaaact gtactagtct gtgtgggact gtacacactt
3241 tatttacttc gttttggtta agttggcttc tgtttctagt tgaggagttt cctaaaagtt
3301 cataacagtg ccattgtctt tatatgaaca tagactagag aaaccgtcct ctttttccat
3361 cataattcta atctaacaat ggaagatttg cccatttaca cttttgagac tttttggtgg
3421 atgtaaataa ccccattctt tgcttgaaca cagtatcttc ccaatagcac tttcattgcc
3481 agtgtctttc tttggtgcct ttcctgttca gcattcttag cctgtggcaa taaagagaaa
3541 ctttgtgcta catgacgaca aagctgctaa atctcctatt tttttaaaat cactaacatt
3601 atattgcaat gaaggaaata aaaaagtctc tatttaaatt cttttttaaa ttttcttcag
3661 ttggtgtgtt tttgggatgt cttattttta gatggttaca ctgttagaac actattttca
3721 gaatctgaat gtaatttgtg taataacg
//