GenBank-Updates@genbank.bio.net (01/12/91)
LOCUS HUMTROC 4567 bp ds-DNA PRI 12-JAN-1991
DEFINITION Human slow twitch skeletal muscle/cardiac muscle troponin C gene,
complete cds.
ACCESSION M37984
KEYWORDS cardiac muscle troponin C; slow twitch skeletal muscle troponin C.
SOURCE Human blood (buffy coat) DNA.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 4567)
AUTHORS Schreier,T., Kedes,L. and Gahlmann,R.
TITLE Cloning, structural analysis, and expression of the human slow
twitch skeletal muscle/cardiac troponin C gene
JOURNAL J. Biol. Chem. 265, 21247-21253 (1990)
STANDARD simple staff_entry
COMMENT Draft entry and computer-readable sequence for [Unpublished (1990)]
kindly submitted
by R.J.Gahlmann, 23-AUG-1990.
University of Southern California
School of Medicine HMR413
2011 Zonal Ave.
Los Angeles, CA 90033
FEATURES Location/Qualifiers
mRNA join(1448..1498,2965..2995,
3226..3372,3621..3735,3952..4088,4173..4377)
/gene="TnC"
/partial
/product="troponin C"
CDS join(1475..1498,2965..2995,
3226..3372,3621..3735,3952..4088,4173..4204)
/gene="TnC"
/product="slow twitch skeletal/cardiac muscle
troponin C"
exon 1448..1498
/number=1
/gene="TnC"
/codon_start=1448
intron 1499..2964
/number=1
/gene="TnC"
exon 2965..2995
/number=2
/gene="TnC"
/codon_start=2965
intron 2996..3225
/gene="TnC"
exon 3226..3372
/number=3
/gene="TnC"
/codon_start=3226
intron 3373..3620
/gene="TnC"
exon 3621..3735
/number=4
/gene="TnC"
/codon_start=3621
intron 3736..3951
/gene="TnC"
exon 3952..4088
/number=5
/gene="TnC"
/codon_start=3952
intron 4089..4172
/number=5
/gene="TnC"
exon 4173..4377
/number=6
/gene="TnC"
/codon_start=4173
BASE COUNT 896 a 1291 c 1424 g 956 t
ORIGIN
1 cctcgcccgc cccgcgcgtg actgacaggg ccactcaggg cgcgcgtgcg aggtgctcgc
61 ttgggtaatc tacctgcgtg ggcccgccgg cggtaccctg cacagcctgc tagaaactga
121 gaccccgggt ggtgacagct ctggcatcgc ccctgggtcc tcgggaagag gggacagaag
181 gtcccgagtc tcccaggcca cacgaagcaa gtcactgctc ttcctggcct cagtttactc
241 ctcctgataa aggaggccat aatagtgcct cacctggctg ttggctcttt ctctttaggg
301 caaggcaggt tggaggggaa aataggacct gtgcttaccg ccggagcagg gcgagagtga
361 ttctgggcca gttctgaacc tctctgagat tcggagatct cttgtcagtg gggcttctgg
421 acaactgagt gggctgattg atgcgcggcc cagcacgcgg cccagtgctc gaggcaggga
481 gcgtgtttat caagagggat aaacttgata cgaactctgt acgaaggaag gtgtaggtgg
541 atggaggggt gtgtgctgcc actgagcaca agaacccacg gggtggcctg ccaaagttca
601 aaacgaggga gacaggttga tctggaccca ggaactacag tgctgaatcc taaaccgggg
661 aaagatgaga cctagaagag ggaggtggta acctaattgg agggtgagga gggaaagagc
721 ctgccacaga tggggcatct ataggggtgc tgttgataac agagcagctg acttaagccc
781 gaagtgggta cttctccctg ggcagatggg aggtctggga caggctcctc tggcagaagg
841 gctcctggcc accctgtcct aaggtgggtc agtcacttcc tccttcacca gttccacagc
901 atcttactat gagcttggca ttcgaggctt ctcttggcag ggccctgcac tcctagcctc
961 tccttgcaca ttgcaccccc attccagaga ggtttagtta aaggcggggg ttaccaagtc
1021 agtcagatct tgggcaagtc accactcctc cagagcctca gtttccttat ctggaaagtg
1081 gaggtcatgg caacccgcca acctggttgg atgggagcct gagctgttgt gttgcacctt
1141 gcctggggcc cacgactttg tagctcctgt cctgcactgg gcttatgttt tcattcattc
1201 cagaaacctt ttcagagagt ccctttgggg agtgtggggg acaggaggga aagaaacctg
1261 gtccttgtag ccgttcgtct gctccctgcc ctgggcagag gacatgggga ctcaggccag
1321 cctgagatca ctgggaccag aggaggggct ggaggatact acacgcaggg gtgggctggg
1381 ctgggctggg ctgggccagg aatgcagcgg ggcagggcta tttaagtcaa gggccggctg
1441 gcaaccccag caagctgtcc tgtgagccgc cagcatggat gacatctaca aggctgcggt
1501 gagggacagg gctgggtagg gctggggtgg gcaggcccac tgggggctca ctcagctgag
1561 agtgcggggt tagtagcccc agggaagtgg tggggaccaa ggagaaggcc tacgtgcctt
1621 caacccaggc cctcacaggg acagtgattc tggtgtttga ggatgcagaa gggggtaggg
1681 ggttccgggt ctgaagggtg gtggaggagg ttgcagcttt ctgatcgtgt ctcactctct
1741 gtttccaagt gtctgtggtc tgtggcactg tcgctcagcc acatgtctct gcatttgtct
1801 ctggacgttt ttgccttcct cttttcatct cttcctcctg agctgtctga gtccccatta
1861 ctgtctccct gtccccaacc cccactttct gcccctcaca ttctgcttct cacatgctca
1921 aaatctgcca cccactccag cccttggcgg gccgaagatg cttggagggt ggagggtgtg
1981 agaggagggg tctgtagagc ctgagtcctg ggctggagat ggggctttga agtttgaggc
2041 agggaagttc tggacatgag ggagaaccaa ggaagaagga acagagaact ggggccccag
2101 ctcccatcat gcctggcagg ctcagggctc agtggcttag ctaggggtga gagcgaggga
2161 atgagggctg gagagtggtc accccaagcc cctgcaacct cctgggtcac tgagggtctt
2221 cagatgctat tctatcctgg gtggtggtac ctccccaacc cagagcaagg acatcctggc
2281 atggccagct gtccccaggg gaacccctcc ctcagcctcc ctcactcctg ggcagggaag
2341 tgctatagcc agctctgggg gcacgcctgc ttatcctgtg ggagtccatg gagccggggt
2401 ggggacagcc ctccacccag tgcccataca aggcctggcg gagttgggga ctaattttgg
2461 cttctgaggc ggcactagca gccagggggc cagataacgc tgccccctgc atgccaaagt
2521 ccccagaaca atcaccaggt ttcactttgt tcctcgttaa aaatagccca gtggccaccc
2581 tggtcaggtt accgtgggtg gcttgcctgc ctccacactg gttttattat cccaacttag
2641 ggacagctgt ccttccggcc cacccagctt gagtttcatc aggggccgaa agggcattga
2701 gtggtcactg actattgtta ctgagggtca ccttggtcct gaagggggtg cccacctgtc
2761 accctggccc tgagcccagt cgcagtgagg ccagctgggt cacgtcaggg ctttgggggc
2821 agggagggag gactgagacc tccactctgt ggcctggaaa tagccagcct cctccagctc
2881 cagccttctc acctgtggaa tgggttggtt cctacgcagc agctatacct gagtctgaga
2941 ccttgagatt ccctttcctt ctaggtagag cagctgacag aagagcagaa aaatggtgag
3001 aatccctatc acacatgtgg gagaccagcg ggtccaggct ggcatgggga ccccttatca
3061 gaagaggacc ccaggccaga gaccagaggc ttggtccctc ttgctctgcc ctcagagagg
3121 tctccgaggg aggtgggcag gttggcaggt ggccccaggg ttctggccct ccgtggtcct
3181 ggctgctgag ccctgactac cgtgcccccc aacccctgaa cacagagttc aaggcagcct
3241 tcgacatctt cgtgctgggc gctgaggatg gctgcatcag caccaaggag ctgggcaagg
3301 tgatgaggat gctgggccag aaccccaccc ctgaggagct gcaggagatg atcgatgagg
3361 tggacgagga cggtgagccc ccctcctccc caggctccag aagaacccca gctggctggg
3421 ggctggaatg ctggctctgt ttagctggga gcaatttagc ctatccgagc cttggttgcc
3481 tcatctataa aatgggcata agggctacac aagcctggcg tttggtgtga ggatgcggtg
3541 agaacatggg ggttcgtgtc gaaggtgctg cctgcagtac ctaccctggc ctctgtaacg
3601 gccatgctgc ccacccccag gcagcggcac ggtggacttt gatgagttcc tggtcatgat
3661 ggttcggtgc atgaaggacg acagcaaagg gaaatctgag gaggagctgt ctgacctctt
3721 ccgcatgttt gacaagtgag cacgtgaccc ttgacctctg accctgaccc acactcaagc
3781 cgagctgtac aggagggcag tctcagattc caggcctagg gaccctgtgg cctctgcctg
3841 ataggggaga gggatgcccc atctcccagt gtccctgctc tgcctcctgg ggcatgggtg
3901 gggctgcctc atgccctccc cacagcccta ccctgagccc cctccccaca gaaatgctga
3961 tggctacatc gacctggatg agctgaagat aatgctgcag gctacaggcg agaccatcac
4021 ggaggacgac atcgaggagc tcatgaagga cggagacaag aacaacgacg gccgcatcga
4081 ctatgatggt aagcgggtgg gtgggctgat ctcctgcctc catgccctgc ccagccccta
4141 ccctcaaccc acacctgccc ctctttccac agagttcctg gagttcatga agggtgtgga
4201 gtagatgctg accttcaccc agagctgcct atgcccagcc tccaactcca gctgagtcct
4261 ggggttgggg agggggtcgg ggtcccagga cctgagcctg gccatgtcct caaccccaaa
4321 tcccccgact ccctccccag atctgtcctg ggggatgcaa ataaagcctg ctctcccaag
4381 gtctgctatc tggctctggt gtccctgggc cgtggactca tccccaggac ccactcttac
4441 ccaatggccg cttccttccc tgtcctaggc aggctggctg cagagcctgg cgcctgacca
4501 ccgctccaca ctgccttctg caggggggtg agatgagatc ggagactgcc gtgtggcctg
4561 ccctgct
//