GenBank-Updates@genbank.bio.net (01/08/91)
LOCUS HUMG0S19A 4102 bp ds-DNA PRI 08-JAN-1991
DEFINITION Human homologue-1 of gene encoding alpha subunit of murine cytokine
(MIP1/SCI), complete cds.
ACCESSION M23178 M32337
KEYWORDS cytokine; macrophage inflammatory protein.
SOURCE Human lymphocyte DNA, clone LG0S1907.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 4102)
AUTHORS Blum,S., Forsdyke,R.E. and Forsdyke,D.R.
TITLE Three human homologs of a murine gene encoding an inhibitor of stem
cell proliferation
JOURNAL DNA Cell Biol. 9, 589-602 (1990)
STANDARD full staff_review
COMMENT Draft entry and computer-readable sequence for
[DNA Cell Biol. 9, 589-602 (1990)] kindly submitted
by D.R.Forsdyke, 30-JUN-1989 and 23-FEB-1990.
The G0S19 genes are members of the 'small inducible' family of
genes. The
G0S19-1 product is homologous to the alpha subunit of the murine
cytokine MIP1.
FEATURES Location/Qualifiers
CDS join(2081..2153,2842..2956,
3377..3467)
/note="G0S19-1 peptide precursor"
mat_peptide join(2141..2153,2842..2956,
3377..3464)
/note="G0S19-1 peptide"
misc_feature 1298..1304
/note="CK-2 element"
misc_feature 1326..1335
/note="serum-response element (put.)"
misc_feature 1481..1488
/note="AP1-binding element (put.)"
misc_feature 1710..1717
/note="AP1-binding element (put.)"
misc_signal 1967..1972
/note="TATA box"
precursor_RNA 1998..3880
/note="G0S19-1 mRNA and introns"
exon 2081..2153
/note="G0S19-1 peptide precursor, exon 1"
sig_peptide 2081..2140
/note="G0S19-1 peptide signal peptide (put.)"
intron 2154..2841
/note="G0S19-1, intron A"
exon 2842..2956
/note="G0S19-1 peptide precursor, exon 2"
intron 2957..3376
/note="G0S19-1, intron B"
exon 3377..3467
/note="G0S19-1 peptide precursor, exon 3"
BASE COUNT 1143 a 945 c 903 g 1111 t
ORIGIN EcoRI site.
1 gaattccaaa ggcatggtcg cacttggctt ctgtcctctg ttattctcca gcatcaaatg
61 tatcaactct aacccctttg gggggaatac aaggcctgtc ctggtttggt cccaatttag
121 ctttatcatc catattcacc cccactgctc tgcagctcca ctgaagcacc ccctctttcc
181 tctgaaccca caatgtcaca ctcaggactc tgcctcagct gggcactcat ctatagatgc
241 ctaaatcccg ggcagttatc cagacacaac taaagttcca tcccttccat gaagccttcc
301 ccaaccctct ggtggaaggt cacttcttcc cctcgtggga ttctgagctt tcatttcttt
361 ttctactagg agtcctagca ctttcggcta aatgctacaa ttacctgttc atacactcta
421 cctgccccca cgagatcagg ggcatctcag aaacaaagat cattaaaacc aactaaatct
481 atttctcatt ataaaatgag gtatgctgat tgattgtgaa agaataaaat aacaaagtat
541 ggaaaagaaa aaaaagcata taatctggct gagaaggtag agacccttcc acaccactga
601 aattatgtat tgaaaagaat aagtaaaaaa ctgcttcaat ttggcatgat ttatgtaagt
661 atagtatagg atccttaaaa tggttcaaag aaatgggaaa tcaagacttc attttggcca
721 aaaccattga acagaaactt cagcatattt atcaataatt tctttcagat taaacaactg
781 acaacaacct atttttcaac cagtgatgtt ggaaatgttt ttttaaaaat tagtttataa
841 atttgtgggc tgaccaagaa ggtaataaag tctaactaag taaaatgaga aaaattcaga
901 aaaagaaaaa aataagaaaa taaatcaccc agggacctat cacacaaata taagaactat
961 tcattcttta aggcatgtat ttccaagcct ttgtattttt ttccatgctt agggttggca
1021 aggaatatat atatatttgt acaaatatat atgtgtatat gtacaaatac atgtatatat
1081 agtacaaata tatatatata tttgtacaat tcttcagact ttgtagaatt tgtataatgt
1141 cgtatcttgc tttttttaac cactgatgtt ataagcatat ttatgccact tcattcattt
1201 tagagactta ataataaatg atctagtgga taatttatca ttccctgatg gagaaaaatt
1261 tagctttgtt tattttagag ttataaacga tgctgggtca ggtatcttta tgtttgaaga
1321 tggctccata tttgggttgt ttccacagaa ctctttccta gaaatgcttt ttctaggtta
1381 atggctacag atatttctag gcacctgaca tattgacacc cacctctaaa gtatttttat
1441 gatccacaac tagcgtttaa cacagcgccc tagtcactac atgactaata aatagacaaa
1501 tgactgaaac atgacctcat gctttctatt cctccagctt tcattcagtt ctttgcctct
1561 gggaggagga agggttgtgc agccctccac agcatcagcc catcaaccct atccctgtgg
1621 ttatagcagc tgaggaagca gaattgcagc tctgtgggaa ggaatggggc tggagagttc
1681 atgcacagac cagttcttat gagaagggac tgactaagaa tagccttggg ttgacatata
1741 cccctcttca cactcacagg agaaaccatt tccctatgaa actataacaa gtcatgagtt
1801 gagagctgag agttagagaa tagctcaaag atgctattct tggatatcct gagcccctgt
1861 ggtcaccagg gaccctgagt tgtgcaactt agcatgacag catcactacg cttaaaaatt
1921 tccctcctca cccccagatt ccatttcccc atccgccagg gctgcctata aagaggagag
1981 ctggtttcag acttcagaag gacacgggca gcagacagtg gtcagtcctt tcttggctct
2041 gctgacactc gagcccacat tccgtcacct gctcagaatc atgcaggtct ccactgctgc
2101 ccttgctgtc ctcctctgca ccatggctct ctgcaaccag ttctctgcat cacgtgagtc
2161 tgagtttcgt tgtgggtatc accactctct ggccatggtt agaccacatc aatcttttct
2221 tgtggcctaa aagcccccaa gagaaaagag aacttcttaa agggctgcca aacatcttgg
2281 tctttctctt taagactttt atttttatct ctagaagggg tcttagcccc ctagtctcca
2341 ggtatgagaa tctaggcagg ggcaggggag ttacagtccc ttttacagat agaaaaacag
2401 ggttcgaaac gaatcagtta gcaagaggca gaatccaggg ctgcttactt cccagtgggg
2461 tatgttgttc actctccagc tcactctagg tctcccagga gctctgtccc ttggatgtct
2521 tatgagagat gtccaaggct tctcttgggt tggggtatga cttcttgaac cagacaaaat
2581 tccctgaaga gaactgagat aagagaacag tccgttcagg tatctggatc acacagagaa
2641 acagagaacc cactatgaag agtcaaggag aaagaaggat acagacagaa acaaagagac
2701 atttctcagc aaaaatgccc aaatgccttc cagtcacttg gtctgagcaa gcctgccttc
2761 ctcaactgct cggggatcag aagctgcctg gccttttctt ctgagctgtg actcgggctc
2821 attctcttcc tttctccaca gttgctgctg acacgccgac cgcctgctgc ttcagctaca
2881 cctcccggca gattccacag aatttcatag ctgactactt tgagacgagc agccagtgct
2941 ccaagcccgg tgtcatgtaa gtgccagtct tcctgctcac ctctatggag gtagggaggg
3001 tcagggttgg ggcagagaca ggccagaagg ctatcctgga aaggcccagc cttcaggagc
3061 ctatcgggga tacaggacgc agggctccga ggtgtgacct gacttggagc tggagtgagg
3121 catgtgttac agagtcagga agggctgccc cagcccagag gaaagggaca ggaagaagga
3181 ggcagcggga cactctgagg gccaccccta ctgagtcact gagagaagct ctctagacag
3241 agataggcag ggggcccctg aaagaggagc aagccctgag ctgcccagga cagagagcag
3301 aatggtgggg ccatggtggg cccaggattc ccctgctgga ttccccagtg cttaactctt
3361 cctcccttct ccacagcttc ctaaccaagc gaagccggca ggtctgtgct gaccccagtg
3421 aggagtgggt ccagaaatat gtcagcgacc tggagctgag tgcctgaggg gtccagaagc
3481 ttcgaggccc agcgacctcg gtgggcccag tggggaggag caggagcctg agccttggga
3541 acatgcgtgt gacctccaca gctacctctt ctatggactg gttgttgcca aacagccaca
3601 ctgtgggact cttcttaact taaattttaa tttatttata ctatttagtt tttgtaattt
3661 attttcgatt tcacagtgtg tttgtgattg tttgctctga gagttcccct gtcccctccc
3721 ccttccctca caccgcgtct ggtgacaacc gagtggctgt catcagcctg tgtaggcagt
3781 catggcacca aagccaccag actgacaaat gtgtatcgga tgcttttgtt cagggctgtg
3841 atcggcctgg ggaaataata aagatgctct tttaaaaggt aaaccagtat tgagtttggt
3901 tttgtttttc tggcaaatca aaatcactgg ttaagaggaa tcataggcaa agattaggaa
3961 gaggtgaaat ggagggaaat tgggagagat ggggagggct accacagagt tatccacttt
4021 acaacggaga cacagttctg gaacattgaa actacgaata tgttataact caaatcataa
4081 catgcatgct ctaggagaat tc
//GenBank-Updates@genbank.bio.net (01/15/91)
LOCUS HUMG0S19A 4102 bp ds-DNA PRI 14-JAN-1991
DEFINITION Human homologue-1 of gene encoding alpha subunit of murine cytokine
(MIP1/SCI), complete cds.
ACCESSION M23178 M32337
KEYWORDS cytokine; macrophage inflammatory protein.
SOURCE Human lymphocyte DNA, clone LG0S1907.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 4102)
AUTHORS Blum,S., Forsdyke,R.E. and Forsdyke,D.R.
TITLE Three human homologs of a murine gene encoding an inhibitor of stem
cell proliferation
JOURNAL DNA Cell Biol. 9, 589-602 (1990)
STANDARD full staff_review
COMMENT Draft entry and computer-readable sequence for
[DNA Cell Biol. 9, 589-602 (1990)] kindly submitted
by D.R.Forsdyke, 30-JUN-1989 and 23-FEB-1990.
The G0S19 genes are members of the 'small inducible' family of
genes. The
G0S19-1 product is homologous to the alpha subunit of the murine
cytokine MIP1.
FEATURES Location/Qualifiers
CDS join(2081..2153,2842..2956,
3377..3467)
/note="G0S19-1 peptide precursor"
mat_peptide join(2141..2153,2842..2956,
3377..3464)
/note="G0S19-1 peptide"
misc_feature 1298..1304
/note="CK-2 element"
misc_feature 1326..1335
/note="serum-response element (put.)"
misc_feature 1481..1488
/note="AP1-binding element (put.)"
misc_feature 1710..1717
/note="AP1-binding element (put.)"
misc_signal 1967..1972
/note="TATA box"
precursor_RNA 1998..3880
/note="G0S19-1 mRNA and introns"
exon 2081..2153
/note="G0S19-1 peptide precursor, exon 1"
sig_peptide 2081..2140
/note="G0S19-1 peptide signal peptide (put.)"
intron 2154..2841
/note="G0S19-1, intron A"
exon 2842..2956
/note="G0S19-1 peptide precursor, exon 2"
intron 2957..3376
/note="G0S19-1, intron B"
exon 3377..3467
/note="G0S19-1 peptide precursor, exon 3"
BASE COUNT 1143 a 945 c 903 g 1111 t
ORIGIN EcoRI site.
1 gaattccaaa ggcatggtcg cacttggctt ctgtcctctg ttattctcca gcatcaaatg
61 tatcaactct aacccctttg gggggaatac aaggcctgtc ctggtttggt cccaatttag
121 ctttatcatc catattcacc cccactgctc tgcagctcca ctgaagcacc ccctctttcc
181 tctgaaccca caatgtcaca ctcaggactc tgcctcagct gggcactcat ctatagatgc
241 ctaaatcccg ggcagttatc cagacacaac taaagttcca tcccttccat gaagccttcc
301 ccaaccctct ggtggaaggt cacttcttcc cctcgtggga ttctgagctt tcatttcttt
361 ttctactagg agtcctagca ctttcggcta aatgctacaa ttacctgttc atacactcta
421 cctgccccca cgagatcagg ggcatctcag aaacaaagat cattaaaacc aactaaatct
481 atttctcatt ataaaatgag gtatgctgat tgattgtgaa agaataaaat aacaaagtat
541 ggaaaagaaa aaaaagcata taatctggct gagaaggtag agacccttcc acaccactga
601 aattatgtat tgaaaagaat aagtaaaaaa ctgcttcaat ttggcatgat ttatgtaagt
661 atagtatagg atccttaaaa tggttcaaag aaatgggaaa tcaagacttc attttggcca
721 aaaccattga acagaaactt cagcatattt atcaataatt tctttcagat taaacaactg
781 acaacaacct atttttcaac cagtgatgtt ggaaatgttt ttttaaaaat tagtttataa
841 atttgtgggc tgaccaagaa ggtaataaag tctaactaag taaaatgaga aaaattcaga
901 aaaagaaaaa aataagaaaa taaatcaccc agggacctat cacacaaata taagaactat
961 tcattcttta aggcatgtat ttccaagcct ttgtattttt ttccatgctt agggttggca
1021 aggaatatat atatatttgt acaaatatat atgtgtatat gtacaaatac atgtatatat
1081 agtacaaata tatatatata tttgtacaat tcttcagact ttgtagaatt tgtataatgt
1141 cgtatcttgc tttttttaac cactgatgtt ataagcatat ttatgccact tcattcattt
1201 tagagactta ataataaatg atctagtgga taatttatca ttccctgatg gagaaaaatt
1261 tagctttgtt tattttagag ttataaacga tgctgggtca ggtatcttta tgtttgaaga
1321 tggctccata tttgggttgt ttccacagaa ctctttccta gaaatgcttt ttctaggtta
1381 atggctacag atatttctag gcacctgaca tattgacacc cacctctaaa gtatttttat
1441 gatccacaac tagcgtttaa cacagcgccc tagtcactac atgactaata aatagacaaa
1501 tgactgaaac atgacctcat gctttctatt cctccagctt tcattcagtt ctttgcctct
1561 gggaggagga agggttgtgc agccctccac agcatcagcc catcaaccct atccctgtgg
1621 ttatagcagc tgaggaagca gaattgcagc tctgtgggaa ggaatggggc tggagagttc
1681 atgcacagac cagttcttat gagaagggac tgactaagaa tagccttggg ttgacatata
1741 cccctcttca cactcacagg agaaaccatt tccctatgaa actataacaa gtcatgagtt
1801 gagagctgag agttagagaa tagctcaaag atgctattct tggatatcct gagcccctgt
1861 ggtcaccagg gaccctgagt tgtgcaactt agcatgacag catcactacg cttaaaaatt
1921 tccctcctca cccccagatt ccatttcccc atccgccagg gctgcctata aagaggagag
1981 ctggtttcag acttcagaag gacacgggca gcagacagtg gtcagtcctt tcttggctct
2041 gctgacactc gagcccacat tccgtcacct gctcagaatc atgcaggtct ccactgctgc
2101 ccttgctgtc ctcctctgca ccatggctct ctgcaaccag ttctctgcat cacgtgagtc
2161 tgagtttcgt tgtgggtatc accactctct ggccatggtt agaccacatc aatcttttct
2221 tgtggcctaa aagcccccaa gagaaaagag aacttcttaa agggctgcca aacatcttgg
2281 tctttctctt taagactttt atttttatct ctagaagggg tcttagcccc ctagtctcca
2341 ggtatgagaa tctaggcagg ggcaggggag ttacagtccc ttttacagat agaaaaacag
2401 ggttcgaaac gaatcagtta gcaagaggca gaatccaggg ctgcttactt cccagtgggg
2461 tatgttgttc actctccagc tcactctagg tctcccagga gctctgtccc ttggatgtct
2521 tatgagagat gtccaaggct tctcttgggt tggggtatga cttcttgaac cagacaaaat
2581 tccctgaaga gaactgagat aagagaacag tccgttcagg tatctggatc acacagagaa
2641 acagagaacc cactatgaag agtcaaggag aaagaaggat acagacagaa acaaagagac
2701 atttctcagc aaaaatgccc aaatgccttc cagtcacttg gtctgagcaa gcctgccttc
2761 ctcaactgct cggggatcag aagctgcctg gccttttctt ctgagctgtg actcgggctc
2821 attctcttcc tttctccaca gttgctgctg acacgccgac cgcctgctgc ttcagctaca
2881 cctcccggca gattccacag aatttcatag ctgactactt tgagacgagc agccagtgct
2941 ccaagcccgg tgtcatgtaa gtgccagtct tcctgctcac ctctatggag gtagggaggg
3001 tcagggttgg ggcagagaca ggccagaagg ctatcctgga aaggcccagc cttcaggagc
3061 ctatcgggga tacaggacgc agggctccga ggtgtgacct gacttggagc tggagtgagg
3121 catgtgttac agagtcagga agggctgccc cagcccagag gaaagggaca ggaagaagga
3181 ggcagcggga cactctgagg gccaccccta ctgagtcact gagagaagct ctctagacag
3241 agataggcag ggggcccctg aaagaggagc aagccctgag ctgcccagga cagagagcag
3301 aatggtgggg ccatggtggg cccaggattc ccctgctgga ttccccagtg cttaactctt
3361 cctcccttct ccacagcttc ctaaccaagc gaagccggca ggtctgtgct gaccccagtg
3421 aggagtgggt ccagaaatat gtcagcgacc tggagctgag tgcctgaggg gtccagaagc
3481 ttcgaggccc agcgacctcg gtgggcccag tggggaggag caggagcctg agccttggga
3541 acatgcgtgt gacctccaca gctacctctt ctatggactg gttgttgcca aacagccaca
3601 ctgtgggact cttcttaact taaattttaa tttatttata ctatttagtt tttgtaattt
3661 attttcgatt tcacagtgtg tttgtgattg tttgctctga gagttcccct gtcccctccc
3721 ccttccctca caccgcgtct ggtgacaacc gagtggctgt catcagcctg tgtaggcagt
3781 catggcacca aagccaccag actgacaaat gtgtatcgga tgcttttgtt cagggctgtg
3841 atcggcctgg ggaaataata aagatgctct tttaaaaggt aaaccagtat tgagtttggt
3901 tttgtttttc tggcaaatca aaatcactgg ttaagaggaa tcataggcaa agattaggaa
3961 gaggtgaaat ggagggaaat tgggagagat ggggagggct accacagagt tatccacttt
4021 acaacggaga cacagttctg gaacattgaa actacgaata tgttataact caaatcataa
4081 catgcatgct ctaggagaat tc
//