GenBank-Updates@genbank.bio.net (01/08/91)
LOCUS HUMG0S19B 4788 bp ds-DNA PRI 08-JAN-1991
DEFINITION Human homologue-2 of gene encoding alpha subunit of murine cytokine
(MIP1/SCI), complete cds.
ACCESSION M24110 M32338
KEYWORDS Alu repetitive sequence; cytokine; macrophage inflammatory protein.
SOURCE Human lymphocyte DNA, clone LG0S1906.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 4788)
AUTHORS Blum,S., Forsdyke,R.E. and Forsdyke,D.R.
TITLE Three human homologs of a murine gene encoding an inhibitor of stem
cell proliferation
JOURNAL DNA Cell Biol. 9, 589-602 (1990)
STANDARD full staff_review
COMMENT Draft entry and computer-readable sequence for
[DNA Cell Biol. 9, 589-602 (1990)] kindly submitted
by D.R.Forsdyke, 30-JUN-1989 and 23-FEB-1990.
The G0S19 genes are members of the 'small inducible' family of
genes. The G0S19-2 product is homologous to the alpha subunit of
the murine cytokine MIP1.
FEATURES Location/Qualifiers
CDS join(2217..2292,2978..3092,
3514..3604)
/note="G0S19-2 peptide precursor"
mat_peptide join(2286..2292,2978..3092,
3514..3601)
/note="G0S19-2 peptide"
misc_feature 1126..1132
/note="CK-2 element"
misc_feature 1154..1163
/note="serum-response element"
repeat_region 1525..1821
/note="Alu repeat"
misc_signal 2103..2108
/note="TATA box"
precursor_RNA 2134..4018
/note="G0S19-2 mRNA and introns"
exon 2217..2292
/note="G0S19-2 peptide precursor, exon 1"
sig_peptide 2217..2285
/note="G0S19-2 peptide signal peptide"
intron 2293..2977
/note="G0S19-2, intron A"
exon 2978..3092
/note="G0S19-2 peptide precursor, exon 2"
intron 3093..3513
/note="G0S19-2, intron B"
exon 3514..3604
/note="G0S19-2 peptide precursor, exon 3"
BASE COUNT 1299 a 1121 c 1050 g 1318 t
ORIGIN EcoRI site.
1 gaattcaagg cctgtcctgg tttggtccca atttaccttt atcatccata ttcaccccca
61 ctgctctgca gctccactga agcaccccct ctttcctctg agccacaatg tcacacccag
121 gactctgcct cagctgggcc tccactgccc acccatctat agatgcctaa atcccgggca
181 gttatccaga cacaactaaa gttccatccc ttccatgaag ccttccccaa ccctctggtg
241 gaaggtcact tcttcctcat ggggttctga gctttcattt ctttttctac taagagtttt
301 acaattacct gttcatacac tctacctgcc cccatgagac caggggcatc tcagaaacaa
361 agatcattaa aaccaactaa atctatttct cattataaaa tgagatatgc tgattgattg
421 caaaataata aaataacaaa gtatggaaaa gaaaaaaaaa agcatataat ctggctgaga
481 aggtagagac ccttccacac cactgaaatt atgtgttgaa aagaataagg aaaaaactgc
541 ttcagtttgg cattatttat gtaagtatag tataggatcc ttaaaatggt tcaaagaaat
601 gggaaatcaa gacttcattt tggcaaagcc attgaacaga aactgtagca tatttatcag
661 taatttcttt cagattaaac aactgacaac aacccacttt tcaaccagtg atgttggaaa
721 tgttttaaaa caaaattagt tcataaattt gtgggttgac caagaaggta ataaagtctc
781 actaaataaa atgaggaaaa ttcagaaaaa gaaaaaaata agaaaataaa tcacccatgg
841 atctaagcac tattcattct ttaaggcatg tatttccaag ccttttaatt ttttcatgcc
901 tagagttggc atggcatata tatatcttta tacaattctt caaattttat agaatttgta
961 taatgtttta tcttgctttt tttttaacca ctgatgttat aagcatattt atgccacttc
1021 attcacgtta gagacttaat aataaaggat cttgtggata atttatcatt ccctgataga
1081 gaaaaattta gctttgctta ttttagagtt ataaatgatg ctgggtcagg tatctttatg
1141 tttgaagatg gctccatatt tgggttgttt ccacagaact ctttccagaa atgctttttc
1201 taggttaatg gctacacata tttctaggca cctgacatac tgacacccac ctctaaagta
1261 tttttatgat ccacaactag cgtttaacac agcgccccag tcactccgag actaataaat
1321 agacaaatga ctgaaacgtg acctcatgct ttctattcct ccagctttca ttgagttcct
1381 ttcctctggg aggactgggg gttgtctagc cctccacagc atcagcccat tgaccctatc
1441 cttgtggtta tagcagctga ggaagcagaa ttacagctct gtgggaagga atggggctgg
1501 agagttcatg catagaccaa ttcttttttt tttttttttt tgagatggag tttcactttt
1561 gttgcccagg ctggagtgca atggcatgat ctcagctcac cacagccccc acctcctggg
1621 ttcaagcgat tctcctgccc tcagcctccc gagtagctgg gattacaggc atgtgccacc
1681 acgcctgact acttttgtat ttttagtaga gatggagttt ctctttcttg gtcaggttgg
1741 tctcaaactc ctgacctcag gtgatctgca gcctcggcct ccaaagtgtt gggattacag
1801 gtgtgagcga ccatgcctgg ctgcatagac cagttcttat gagaagggat caactaagaa
1861 tagccttggg ttgacacaca cccctcttca cactcacagg agaaacccca tgaagctaga
1921 accagtcatg agttgagagc tgagagttag agagtagctc agagatgcta ttcttggata
1981 tcctgagccc ctgtggtcac cagggaccct gagttgtgca acactcagca tgacagcatc
2041 actacactta aaaatttccc tcctcacccc cagattccat ttccccatcc gccagggctg
2101 cctataaaga ggagagatgg cttcagacat cagaaggacg caggcagcaa agagtagtca
2161 gtcccttctt ggctctgctg acactcgagc ccacattcca tcacctgctc ccaatcatgc
2221 aggtctccac tgctgccctt gccgtcctcc tctgcaccat ggctctctgc aaccaggtcc
2281 tctctgcacc acgtgagtcc atgttgttgt tgtgggtatc accactctct ggccatggtt
2341 agaccacatc agtctttttt tgtggcgtga gaggccccga agagaaaaga aggaagttct
2401 taaagcgctg ccaaacacct tggtcttttt cttcacaact tttattttta tctctagaag
2461 gggtcttagc cctcctagtc tccaggtatg agaatctagg caggggcagg ggagttacag
2521 tcccttgtac agatagaaaa acagggttca aaacgaatca gtttgcaaga ggcagaatcc
2581 agggctgctt acttcccagt ggggtctgtt cttcactctc cagctcaccc tagtctccca
2641 ggagccctgt cccttggatg tcttatgaga gatgtccagg gcttctcttg ggctggggta
2701 tgacttcttg aaccgacaaa attccatgaa gagagctaag agaacagtcc attcaggtat
2761 ctggatcaca tagagaaaca gagaacccac tatgaagagt caaggggaaa gaggaatata
2821 gacagaaaca aagagacatt tctctgcaaa accccccaaa tgccttgcag tcacttggtc
2881 tgagcaagcc tgccctcctc aaccactcag ggatcagaag ctgcctggcc ttttcttctg
2941 agctgtgact tgggcttatt ctctcctttc tccgcagttg ctgctgacac gccgaccgcc
3001 tgctgcttca gctacacctc ccgacagatt ccacagaatt tcatagctga ctactttgag
3061 acgagcagcc agtgctccaa gcccagtgtc atgtaagtgc cagtcttcct gctcacctct
3121 agggaggtag ggagtgtcag ggtgggggca gaaacaggcc agaaggccat cctggaaagg
3181 cccagccttc aggagcctat cggggataca ggacgcaggg cactgaggtg tgacctgact
3241 tggggctgga gtgaggtggg tgttacagag tcaggaaggg ctgccccagg ccagaggaaa
3301 gggacaggaa gaaggaggca gcaggacact ctgagggccc ccttgcctgg agtcactgag
3361 agaagctctc tagacggaga taggcagggg gcccctgaga gaggagcagg ccttgagctg
3421 cccaggacag agagcaggat gtcagggcca tggtgggccc aggattcccc ggctggattc
3481 cccagtgctt aactcttcct cccttctcca cagcttccta accaagagag gccggcaggt
3541 ctgtgctgac cccagtgagg agtgggtcca gaaatacgtc agtgacctgg agctgagtgc
3601 ctgaggggtc cagaagcttc gaggcccagc gacctcagtg ggcccagtgg ggaggagcag
3661 gagcctgagc cttgggaaca tgcgtgtgac ctccacagct acctcttcta tggactggtt
3721 attgccaaac agccacactg tgggactctt cttaacttaa attttaattt atttatacta
3781 tttagttttt ataatttatt tttgatttca cagtgtgttt gtgattgttt gctctgagag
3841 ttccccctgt cccctccacc ttccctcaca gtgtgtctgg tgacaaccga gtggctgtca
3901 tcggcctgtg taggcagtca tggcaccaaa gccaccagac tgacaaatgt gtatcagatg
3961 cttttgttca gggctgtgat cggcctgggg aaataataaa gatgttcttt taaacggtaa
4021 accagtattg agtttggttt tgtttttctg gcaaatcaaa atcactggtt aagaggaatc
4081 ataggcaaag attaggaaga ggtgaaatgg agggaaattg ggagagatgg ggagcgctgc
4141 gacagagtta tccacttcac aaaattctgg aacattgaaa ctacgaatat gttataactc
4201 aaatcgtaat atgcacgctc taggagaatt aactacttga atggccacca ttaagcagag
4261 tattctgtag ggcatattca tgatgaatca agctcttaat agcaattatt tacattgttg
4321 aggcttactc ctcctactga gtgcttttta tacattgttc atttaatctt accaatgcaa
4381 tagtacagct taggtactat taatacctcc acttgacaga aaagtaaccc agggctcaga
4441 aaggttagac aacttggctg aggttacaca gcacgtaaac ggtcaattgt gttccaaaac
4501 tggactttta ttgaactaca gactatgctg ttaaccattg accaagttat ttcccaaagt
4561 atgacccgcc tatactcaaa tcttacccca ttctttaaca gatgatactt tatccattgc
4621 aaccacttcc tgtcaggatt ctgagttgac atagagtgtt tcagcagtga ttatttaagc
4681 caattacatc aggatcttta ggtgtagacc tgggaactga tatttttatc aagctcatga
4741 ggtgttccat agcatgttaa tgactgagag ccactgtcaa tagaattc
//GenBank-Updates@genbank.bio.net (01/15/91)
LOCUS HUMG0S19B 4788 bp ds-DNA PRI 14-JAN-1991
DEFINITION Human homologue-2 of gene encoding alpha subunit of murine cytokine
(MIP1/SCI), complete cds.
ACCESSION M24110 M32338
KEYWORDS Alu repetitive sequence; cytokine; macrophage inflammatory protein.
SOURCE Human lymphocyte DNA, clone LG0S1906.
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 4788)
AUTHORS Blum,S., Forsdyke,R.E. and Forsdyke,D.R.
TITLE Three human homologs of a murine gene encoding an inhibitor of stem
cell proliferation
JOURNAL DNA Cell Biol. 9, 589-602 (1990)
STANDARD full staff_review
COMMENT Draft entry and computer-readable sequence for
[DNA Cell Biol. 9, 589-602 (1990)] kindly submitted
by D.R.Forsdyke, 30-JUN-1989 and 23-FEB-1990.
The G0S19 genes are members of the 'small inducible' family of
genes. The G0S19-2 product is homologous to the alpha subunit of
the murine cytokine MIP1.
FEATURES Location/Qualifiers
CDS join(2217..2292,2978..3092,
3514..3604)
/note="G0S19-2 peptide precursor"
mat_peptide join(2286..2292,2978..3092,
3514..3601)
/note="G0S19-2 peptide"
misc_feature 1126..1132
/note="CK-2 element"
misc_feature 1154..1163
/note="serum-response element"
repeat_region 1525..1821
/note="Alu repeat"
misc_signal 2103..2108
/note="TATA box"
precursor_RNA 2134..4018
/note="G0S19-2 mRNA and introns"
exon 2217..2292
/note="G0S19-2 peptide precursor, exon 1"
sig_peptide 2217..2285
/note="G0S19-2 peptide signal peptide"
intron 2293..2977
/note="G0S19-2, intron A"
exon 2978..3092
/note="G0S19-2 peptide precursor, exon 2"
intron 3093..3513
/note="G0S19-2, intron B"
exon 3514..3604
/note="G0S19-2 peptide precursor, exon 3"
BASE COUNT 1299 a 1121 c 1050 g 1318 t
ORIGIN EcoRI site.
1 gaattcaagg cctgtcctgg tttggtccca atttaccttt atcatccata ttcaccccca
61 ctgctctgca gctccactga agcaccccct ctttcctctg agccacaatg tcacacccag
121 gactctgcct cagctgggcc tccactgccc acccatctat agatgcctaa atcccgggca
181 gttatccaga cacaactaaa gttccatccc ttccatgaag ccttccccaa ccctctggtg
241 gaaggtcact tcttcctcat ggggttctga gctttcattt ctttttctac taagagtttt
301 acaattacct gttcatacac tctacctgcc cccatgagac caggggcatc tcagaaacaa
361 agatcattaa aaccaactaa atctatttct cattataaaa tgagatatgc tgattgattg
421 caaaataata aaataacaaa gtatggaaaa gaaaaaaaaa agcatataat ctggctgaga
481 aggtagagac ccttccacac cactgaaatt atgtgttgaa aagaataagg aaaaaactgc
541 ttcagtttgg cattatttat gtaagtatag tataggatcc ttaaaatggt tcaaagaaat
601 gggaaatcaa gacttcattt tggcaaagcc attgaacaga aactgtagca tatttatcag
661 taatttcttt cagattaaac aactgacaac aacccacttt tcaaccagtg atgttggaaa
721 tgttttaaaa caaaattagt tcataaattt gtgggttgac caagaaggta ataaagtctc
781 actaaataaa atgaggaaaa ttcagaaaaa gaaaaaaata agaaaataaa tcacccatgg
841 atctaagcac tattcattct ttaaggcatg tatttccaag ccttttaatt ttttcatgcc
901 tagagttggc atggcatata tatatcttta tacaattctt caaattttat agaatttgta
961 taatgtttta tcttgctttt tttttaacca ctgatgttat aagcatattt atgccacttc
1021 attcacgtta gagacttaat aataaaggat cttgtggata atttatcatt ccctgataga
1081 gaaaaattta gctttgctta ttttagagtt ataaatgatg ctgggtcagg tatctttatg
1141 tttgaagatg gctccatatt tgggttgttt ccacagaact ctttccagaa atgctttttc
1201 taggttaatg gctacacata tttctaggca cctgacatac tgacacccac ctctaaagta
1261 tttttatgat ccacaactag cgtttaacac agcgccccag tcactccgag actaataaat
1321 agacaaatga ctgaaacgtg acctcatgct ttctattcct ccagctttca ttgagttcct
1381 ttcctctggg aggactgggg gttgtctagc cctccacagc atcagcccat tgaccctatc
1441 cttgtggtta tagcagctga ggaagcagaa ttacagctct gtgggaagga atggggctgg
1501 agagttcatg catagaccaa ttcttttttt tttttttttt tgagatggag tttcactttt
1561 gttgcccagg ctggagtgca atggcatgat ctcagctcac cacagccccc acctcctggg
1621 ttcaagcgat tctcctgccc tcagcctccc gagtagctgg gattacaggc atgtgccacc
1681 acgcctgact acttttgtat ttttagtaga gatggagttt ctctttcttg gtcaggttgg
1741 tctcaaactc ctgacctcag gtgatctgca gcctcggcct ccaaagtgtt gggattacag
1801 gtgtgagcga ccatgcctgg ctgcatagac cagttcttat gagaagggat caactaagaa
1861 tagccttggg ttgacacaca cccctcttca cactcacagg agaaacccca tgaagctaga
1921 accagtcatg agttgagagc tgagagttag agagtagctc agagatgcta ttcttggata
1981 tcctgagccc ctgtggtcac cagggaccct gagttgtgca acactcagca tgacagcatc
2041 actacactta aaaatttccc tcctcacccc cagattccat ttccccatcc gccagggctg
2101 cctataaaga ggagagatgg cttcagacat cagaaggacg caggcagcaa agagtagtca
2161 gtcccttctt ggctctgctg acactcgagc ccacattcca tcacctgctc ccaatcatgc
2221 aggtctccac tgctgccctt gccgtcctcc tctgcaccat ggctctctgc aaccaggtcc
2281 tctctgcacc acgtgagtcc atgttgttgt tgtgggtatc accactctct ggccatggtt
2341 agaccacatc agtctttttt tgtggcgtga gaggccccga agagaaaaga aggaagttct
2401 taaagcgctg ccaaacacct tggtcttttt cttcacaact tttattttta tctctagaag
2461 gggtcttagc cctcctagtc tccaggtatg agaatctagg caggggcagg ggagttacag
2521 tcccttgtac agatagaaaa acagggttca aaacgaatca gtttgcaaga ggcagaatcc
2581 agggctgctt acttcccagt ggggtctgtt cttcactctc cagctcaccc tagtctccca
2641 ggagccctgt cccttggatg tcttatgaga gatgtccagg gcttctcttg ggctggggta
2701 tgacttcttg aaccgacaaa attccatgaa gagagctaag agaacagtcc attcaggtat
2761 ctggatcaca tagagaaaca gagaacccac tatgaagagt caaggggaaa gaggaatata
2821 gacagaaaca aagagacatt tctctgcaaa accccccaaa tgccttgcag tcacttggtc
2881 tgagcaagcc tgccctcctc aaccactcag ggatcagaag ctgcctggcc ttttcttctg
2941 agctgtgact tgggcttatt ctctcctttc tccgcagttg ctgctgacac gccgaccgcc
3001 tgctgcttca gctacacctc ccgacagatt ccacagaatt tcatagctga ctactttgag
3061 acgagcagcc agtgctccaa gcccagtgtc atgtaagtgc cagtcttcct gctcacctct
3121 agggaggtag ggagtgtcag ggtgggggca gaaacaggcc agaaggccat cctggaaagg
3181 cccagccttc aggagcctat cggggataca ggacgcaggg cactgaggtg tgacctgact
3241 tggggctgga gtgaggtggg tgttacagag tcaggaaggg ctgccccagg ccagaggaaa
3301 gggacaggaa gaaggaggca gcaggacact ctgagggccc ccttgcctgg agtcactgag
3361 agaagctctc tagacggaga taggcagggg gcccctgaga gaggagcagg ccttgagctg
3421 cccaggacag agagcaggat gtcagggcca tggtgggccc aggattcccc ggctggattc
3481 cccagtgctt aactcttcct cccttctcca cagcttccta accaagagag gccggcaggt
3541 ctgtgctgac cccagtgagg agtgggtcca gaaatacgtc agtgacctgg agctgagtgc
3601 ctgaggggtc cagaagcttc gaggcccagc gacctcagtg ggcccagtgg ggaggagcag
3661 gagcctgagc cttgggaaca tgcgtgtgac ctccacagct acctcttcta tggactggtt
3721 attgccaaac agccacactg tgggactctt cttaacttaa attttaattt atttatacta
3781 tttagttttt ataatttatt tttgatttca cagtgtgttt gtgattgttt gctctgagag
3841 ttccccctgt cccctccacc ttccctcaca gtgtgtctgg tgacaaccga gtggctgtca
3901 tcggcctgtg taggcagtca tggcaccaaa gccaccagac tgacaaatgt gtatcagatg
3961 cttttgttca gggctgtgat cggcctgggg aaataataaa gatgttcttt taaacggtaa
4021 accagtattg agtttggttt tgtttttctg gcaaatcaaa atcactggtt aagaggaatc
4081 ataggcaaag attaggaaga ggtgaaatgg agggaaattg ggagagatgg ggagcgctgc
4141 gacagagtta tccacttcac aaaattctgg aacattgaaa ctacgaatat gttataactc
4201 aaatcgtaat atgcacgctc taggagaatt aactacttga atggccacca ttaagcagag
4261 tattctgtag ggcatattca tgatgaatca agctcttaat agcaattatt tacattgttg
4321 aggcttactc ctcctactga gtgcttttta tacattgttc atttaatctt accaatgcaa
4381 tagtacagct taggtactat taatacctcc acttgacaga aaagtaaccc agggctcaga
4441 aaggttagac aacttggctg aggttacaca gcacgtaaac ggtcaattgt gttccaaaac
4501 tggactttta ttgaactaca gactatgctg ttaaccattg accaagttat ttcccaaagt
4561 atgacccgcc tatactcaaa tcttacccca ttctttaaca gatgatactt tatccattgc
4621 aaccacttcc tgtcaggatt ctgagttgac atagagtgtt tcagcagtga ttatttaagc
4681 caattacatc aggatcttta ggtgtagacc tgggaactga tatttttatc aagctcatga
4741 ggtgttccat agcatgttaa tgactgagag ccactgtcaa tagaattc
//