GenBank-Updates@genbank.bio.net (01/08/91)
LOCUS HUMTPIA 645 bp ds-DNA PRI 08-JAN-1991
DEFINITION Human triosephosphate isomerase (TPI) gene, 5' end.
ACCESSION J04603 J04604
KEYWORDS triosephosphate isomerase.
SOURCE Human DNA (library of T.Maniatis).
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 645)
AUTHORS Boyer,T.G., Krug,J.R. and Maquat,L.E.
TITLE Transcriptional regulatory sequences of the housekeeping gene for
human triosephosphate isomerase
JOURNAL J. Biol. Chem. 264, 5177-5187 (1989)
STANDARD full staff_review
REFERENCE 2 (sites)
AUTHORS Boyer,T.G. and Maquat,L.E.
TITLE Minimal sequence and factor requirements for the initiation of
transcription from an atypical, TATATAA box-containing housekeeping
promoter
JOURNAL J. Biol. Chem. 265, 20524-20532 (1990)
STANDARD full staff_review
COMMENT Draft entry and printed sequence for [J. Biol. Chem. 264, 5177-5187
(1989)] kindly submitted by T.G.
Boyer, 5-MAY-1989.
FEATURES Location/Qualifiers
misc_binding 458..463
/note="Sp1 binding site"
misc_binding 470..475
/note="Sp1 binding site"
misc_binding 484..489
/note="Sp1 binding site"
misc_binding 488..493
/note="Sp1 binding site"
misc_binding 515..520
/note="Sp1 binding site"
misc_binding 543..548
/note="Sp1 binding site"
misc_signal 569..575
/note="TATA box"
precursor_RNA 596..>645
/note="TPI1 mRNA and introns"
CDS 631..>645
/note="triosephosphate isomerase (EC 5.3.1.1)
/hgml_locus_uid='LH0048S' /nomgen='TPI1' /map='12p13'"
BASE COUNT 105 a 199 c 231 g 110 t
ORIGIN Chromosome 12p13.
1 ctgcagttcc tgccaggcct tgccagccgg ggcgagggtt gggatgatcc tggcggccta
61 tgcctgtgtg ggctgcccct cccgctgtga accctgcatt tgtcccgcaa gttttcactc
121 aggtagactc cctgggtaca aagggtgcct gctcagcagt cgggcatgag ctgctccgat
181 gggcgaagga ggttgtctat tccacagttg gagagggccc tctctgccca gtgggcgatc
241 tgggctacgg ccaagttgcc accagctagt tccgcttgaa aaccacttct ggccccgtgg
301 gggactcaag cggtccaagc gagggttccc ctgagcgccg gagctcacag gtctcgcctt
361 gtcccgaaag cccccgcaat cgaggcggag gcgaccgagc ccccgactct cctagaacgt
421 tgccacaaga aggggaacgt cggaacagtg catcatcggg cggcggccgg ggcggcggca
481 ggagggcggg cggggggcag ggctccgggg gactgggcgg gccatggcgg aggacggcga
541 ggaggcggag ttccacttcg cggcgctcta tataagtggg cagtggccgg actgcgcgca
601 gacactgacc ttcagcgcct cggctcggcc atggcgccct ccagg
//GenBank-Updates@genbank.bio.net (01/15/91)
LOCUS HUMTPIA 645 bp ds-DNA PRI 14-JAN-1991
DEFINITION Human triosephosphate isomerase (TPI) gene, 5' end.
ACCESSION J04603 J04604
KEYWORDS triosephosphate isomerase.
SOURCE Human DNA (library of T.Maniatis).
ORGANISM Homo sapiens
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Primates; Haplorhini; Catarrhini; Hominidae.
REFERENCE 1 (bases 1 to 645)
AUTHORS Boyer,T.G., Krug,J.R. and Maquat,L.E.
TITLE Transcriptional regulatory sequences of the housekeeping gene for
human triosephosphate isomerase
JOURNAL J. Biol. Chem. 264, 5177-5187 (1989)
STANDARD full staff_review
REFERENCE 2 (sites)
AUTHORS Boyer,T.G. and Maquat,L.E.
TITLE Minimal sequence and factor requirements for the initiation of
transcription from an atypical, TATATAA box-containing housekeeping
promoter
JOURNAL J. Biol. Chem. 265, 20524-20532 (1990)
STANDARD full staff_review
COMMENT Draft entry and printed sequence for [J. Biol. Chem. 264, 5177-5187
(1989)] kindly submitted by T.G.
Boyer, 5-MAY-1989.
FEATURES Location/Qualifiers
misc_binding 458..463
/note="Sp1 binding site"
misc_binding 470..475
/note="Sp1 binding site"
misc_binding 484..489
/note="Sp1 binding site"
misc_binding 488..493
/note="Sp1 binding site"
misc_binding 515..520
/note="Sp1 binding site"
misc_binding 543..548
/note="Sp1 binding site"
misc_signal 569..575
/note="TATA box"
precursor_RNA 596..>645
/note="TPI1 mRNA and introns"
CDS 631..>645
/note="triosephosphate isomerase (EC 5.3.1.1)
/hgml_locus_uid='LH0048S' /nomgen='TPI1' /map='12p13'"
BASE COUNT 105 a 199 c 231 g 110 t
ORIGIN Chromosome 12p13.
1 ctgcagttcc tgccaggcct tgccagccgg ggcgagggtt gggatgatcc tggcggccta
61 tgcctgtgtg ggctgcccct cccgctgtga accctgcatt tgtcccgcaa gttttcactc
121 aggtagactc cctgggtaca aagggtgcct gctcagcagt cgggcatgag ctgctccgat
181 gggcgaagga ggttgtctat tccacagttg gagagggccc tctctgccca gtgggcgatc
241 tgggctacgg ccaagttgcc accagctagt tccgcttgaa aaccacttct ggccccgtgg
301 gggactcaag cggtccaagc gagggttccc ctgagcgccg gagctcacag gtctcgcctt
361 gtcccgaaag cccccgcaat cgaggcggag gcgaccgagc ccccgactct cctagaacgt
421 tgccacaaga aggggaacgt cggaacagtg catcatcggg cggcggccgg ggcggcggca
481 ggagggcggg cggggggcag ggctccgggg gactgggcgg gccatggcgg aggacggcga
541 ggaggcggag ttccacttcg cggcgctcta tataagtggg cagtggccgg actgcgcgca
601 gacactgacc ttcagcgcct cggctcggcc atggcgccct ccagg
//