GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS RATVDCCA 8305 bp ds-DNA ROD 16-JAN-1991
DEFINITION Rat dihydropryridine-sensitive calcium channel alpha-1 subunit.
ACCESSION M59786 M34364
KEYWORDS DHP-sensitive channel alpha-1 subunit; L-type calcium channel;
L-type voltage-dependent calcium channel;
dihydropryridine-sensitive calcium channel alpha-1 subunit.
SOURCE Rat aorta cDNA to mRNA.
ORGANISM Rattus sp.
Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia;
Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae.
REFERENCE 1 (bases 1 to 8305)
AUTHORS Koch,W.J., Ellinor,P.T. and Schwartz,A.
TITLE cDNA cloning of a dihydropyridine-sensitive calcium channel from
rat aorta
JOURNAL J. Biol. Chem. 265, 17786-17791 (1990)
STANDARD simple staff_entry
FEATURES Location/Qualifiers
CDS 189..6698
/codon_start=189
/product="dihydropryridine-sensitive calcium
channel alpha-1 subunit"
BASE COUNT 1995 a 2234 c 2115 g 1961 t
ORIGIN
1 cgcagaattc taaatctgag agcaaaagct caaattcact gccaagcgat aaggccgtat
61 gagattttta tggccttcaa acgtggccac agacattgtt tctgagtttt taaaaagtac
121 aaggaaaaat acaagtggga tagctgttca gttgtgacat cagctgttgg tccccaactg
181 gagtcacaat gattcgggcc ttcgctcagc catccacacc cccataccag ccgctctcca
241 gttgcctgtc tgaggacaca gagaggaagt tcaagggcaa ggtggtacac gaagctcaac
301 tcaactgttt ctacatttct cctggaggtt ccaactatgg gagcccacgc ccagctcatg
361 ccaacatgaa tgccaatgca gctgcaggac ttgcccccga gcacatccct actccagggg
421 cagcactgtc ctggctggca gccatcgatg ccgcccggca ggccaagtta atgggcagtg
481 ctggcaatgc gaccatctct accgtcagtt ccacacagcg gaagcggcag cagtatggga
541 aacccaagaa gcaggggggc acaactgcca cacggccgcc ccgggctctg ctctgcctga
601 ctctgaagaa ccccatcagg agggcatgca tcagcattgt tgaatggaaa ccatttgaaa
661 taattatttt attgacgatt tttgccaatt gtgtggcctt agcaatctat attccctttc
721 cggaagatga ctccaacgcc accaactcca acctggaacg ggtggagtat ctcttcctca
781 tcatttttac cgtggaagca tttttaaaag tgattgccta cggactactc ttccacccca
841 acgcttacct ccgcaacggt tggaatttac tagattttat aatcgtggtt gtagggcttt
901 ttagtgcaat tttagaacaa gcaaccaaag ctgacggggc caacgctctg ggagggaaag
961 gagcgggatt cgatgtgaag gcactgagag ctttccgtgt gcttcgtccc ctgcggctgg
1021 tgtctggagt cccaagtctc caggtggtcc tgaactccat catcaaggcc atggtgcccc
1081 tgctgcacat tgccctcctc gtgctcttcg tcatcatcat ctatgccatt atcggcctgg
1141 agctcttcat ggggaagatg cacaagacct gctacaacca ggagggcata atagatgttc
1201 cagcggaaga ggatccctcc ccttgtgctt tggagacagg ccatgggcga cagtgtcaga
1261 acgggaccgt gtgcaagccc gggtgggatg ggcccaagca cggcatcacc aacttcgaca
1321 acttcgcctt cgccatgctg acggtgttcc agtgtatcac catggagggc tggacagacg
1381 tgctgtactg gatgcaagac gctatgggct atgagttgcc ctgggtgtat tttgtcagtc
1441 tggtcatctt tggatccttt ttcgttctaa atctggttct cggtgttttg agcggagagt
1501 tttccaaaga gagggagaaa gccaaagctc gaggagactt ccagaagctt cgtgagaagc
1561 agcagctaga agaagatctc aaaggctacc tggactggat cacccaggcg gaagacatag
1621 accctgagaa tgaggacgag ggcatggatg aagacaaacc ccgaaacatg agcatgccca
1681 caagtgagac tgagtctgtc aacaccgaaa acgtggctgg aggtgacatc gagggtgaaa
1741 actgtggagc ccggcttgcc caccggatct ccaaatccaa gttcagccgc tactggcgcc
1801 ggtggaatag attctgcaga agaaagtgcc gtgccgcagt taagtccaac gtcttctact
1861 ggctggtgat cttcctggtg ttcctcaaca ccctcaccat tgcctccgaa cactacaacc
1921 agcctcattg gctcacagaa gtgcaagaca cggccaacaa ggccctcctg gcccttttca
1981 cggcagaaat gctcctgaag atgtacagcc tgggtctgca ggcctacttt gtatccctct
2041 tcaaccgctt tgactgtttc attgtgtgcg ggggcatcct ggagaccatc ctggtggaga
2101 cgaagatcat gtcgcccctg ggcatctcct gctggagatg tgtgcggctg ctcaggattt
2161 tcaagatcac caggtactgg aactccctga gcaacctcgt ggcgtccttg ctgaactcac
2221 tgcgctccat cgcctccctg ctgctactcc tcttcctctt catcatcatc ttctccctcc
2281 tggggatgca gctgtttggt ggaaagttca actttgatga gatgcagacc cgtaggagca
2341 cgtttgataa cttcccgcag tctctcctca ctgtgtttca gatcctgacc ggggaggact
2401 ggaattcggt gatgtatgat gggatcatgg cttatggcgg cccctctttt ccagggatgt
2461 tagtctgtat ttacttcatc atcctcttca tctctccaaa ttatatccta ctgaatctct
2521 tcttggccat tgcggtggac aacctggctg atgcggagag cctgacctct gcccaaaaag
2581 aggaagaaga agagaaggag agaaagaagc tggccaggac tgccagccca gaaaagaaac
2641 aggaggtgat ggagaaacca gcagtagagg agagcaaaga ggagaaaatt gagctgaagt
2701 ccattacagc agatggagaa tccccgccca ctaccaagat caacatggat gacctccagc
2761 ccagtgaaaa tgaggacaag agtccccact ccaacccaga cactgcaggt gaagaggatg
2821 aggaggagcc cgagatgcct gtgggcccac gcccccggcc cctgtctgag ctgcacctta
2881 aggaaaaggc agtccccatg ccggaagcca gtgcattttt catcttcagc ccaaacaaca
2941 ggttccgcct gcagtgccac cgcattgtca atgacacgat cttcaccaac ctcatcctct
3001 tcttcattct gctcagtagc atctccctgg cggctgagga ccccgtccag cacacctcct
3061 tcaggaacca cattctgttt tattttgaca ttgtttttac caccattttc accattgaaa
3121 ttgctctaaa gatgactgct tacggggctt tcctgcacaa gggctctttc tgccgaaatt
3181 acttcaatat cctggacctg ctggtggtta gcgtgtccct catctccttt ggcattcagt
3241 ccagcgcgat caacgttgtg aagattttaa gagtgcttcg tgtcctcagg cccctgagga
3301 tcaacagggc caaggggcta aagcacgtcg ttcagtgtgt gtttgtggcc atccggacca
3361 ttggaaacat tgtaattgtc accactctgc tgcagttcat gttcgcctgc attggggtcc
3421 agctcttcaa gggaaagctc tatacctgtt cggatagttc caaacagacg gaggcagaat
3481 cgaagggtaa ctatataaca tacaagaccg gagaagttga ccaccccatt atccagcctc
3541 gaagttggga gaacagcaag ttcgactttg acaatgttct ggcagccatg atggccctct
3601 ttaccgtctc caccttcgag gggtggccag agctgctgta ccgctccatt gactcccaca
3661 cagaagacaa gggtcccatc tacaactatc gtgtggagat ctccatcttc ttcatcatct
3721 acatcatcat cattgccttc ttcatgatga acatcttcgt gggtttcgtc attgtcacct
3781 tccaggagca gggggaacaa gaatacaaga actgtgagct ggacaagaac cagagacaat
3841 gtgtggaata tgccctcaag gcccgaccct tgccaaggta catccccaag aaccagcacc
3901 agtacaaagt gtggtacgtg gtcaactcca cctacttcga gtatctgatg ttcgtcctca
3961 tcctgctcaa caccatctgc ctggccatgc agcactacgg ccagagctgc ctcttcaaaa
4021 tcgccatgaa tatactcaac atgcttttca ctggcctctt cacggtggag atgatcctga
4081 agctcattgc cttcaaaccc aagcactatt tctgtgatgc atggaataca tttgacgcct
4141 tgattgttgt gggtagcatt gttgatatag caatcaccga ggtacaccca gctgaacata
4201 cccaatgctc tccctctatg agtgcagagg agaactcccg catctccatc accttcttcc
4261 gcctcttccg ggtcatgcgc ctggtgaagc tgctgagccg aggggaaggc atccggaccc
4321 tgctgtggac cttcatcaag tccttccagg ccctgcccta tgtggccctt ttgattgtga
4381 tgctgttctt tatctatgca gtgattggga tgcaggtatt tgggaagatt gccctgaatg
4441 acaccacaga gatcaatcgg aacaacaact tccagacgtt ccctcaggct gtgctactgc
4501 tcttcaggtg cgccactggg gaggcctggc aggatatcat gctagcctgt atgccaggca
4561 agaagtgtgc tccagagtct gagcccagca acagcacgga aggggagaca ccctgtggca
4621 gcagtttcgc tgtcttctac ttcatcagct tctacatgct ctgtgccttc ctgatcatca
4681 acctctttgt agctgttatc atggacaact ttgactacct gactagggat tggtctatcc
4741 ttggtcccca tcacctggat gaattcaaga gaatctgggc cgaatatgac cctgaagcca
4801 agggtcggat caaacacttg gatgtggtga ccctcctccg tcgaattcag cccccactgg
4861 gttttgggaa gttgtgtcct caccgtgtgg cctgcaaacg cctggtgtcc atgaacatgc
4921 ctctgaacag tgatgggacg gtcatgttca atgctacact gtttgccctt gtcaggacag
4981 ccctgaggat caaaacagaa gggaacctag agcaagccaa tgaggagctg agagccatca
5041 tcaagaaaat ctggaagagg accagcatga agctgttgga ccaggtggtg ccccctgcag
5101 gtgatgacga ggtcacagtg ggcaagttct atgccacctt cctgatccaa gagtacttca
5161 ggaaattcaa gaagcgaaaa gagcaggggc tggtcggcaa gccctcgcag aggaatgcac
5221 tgtctctgca ggctggctta cgcaccttgc atgacattgg gcctgagatc cggagagcca
5281 tctctgggga tctgacggct gaggaggagc tggacaaggc tatgaaggag gcagtgtctg
5341 ctgcctccga agacgacatc ttcaggaggg ctggaggcct gtttggcaac cacgtcagct
5401 actaccagag tgacagcagg agcaacttcc ctcagacgtt tgccacccaa cgcccactgc
5461 acatcaacaa gacagggaac aaccaagcgg acaccgaatc accgtcccat gagaagctgg
5521 tggactccac tttcaccccc agcagctact catccacggg ctccaatgcc aacatcaaca
5581 atgccaacaa cactgccctg ggccgcttcc cccaccctgc tggctactcc agcacggtca
5641 gcactgtgga gggccatggg cctcccttgt cccctgctgt ccgggtacag gaggcagcat
5701 ggaaactcag ctctaagagg tgccactccc gagagagcca gggggccacg gtgagtcagg
5761 atatgtttcc agatgagacc cgcagcagcg tgaggctgag cgaagaagtt gagtactgca
5821 gtgagcccag cctgctctcc acagatatac tctcctacca ggacgatgaa aaccgacaac
5881 tgacctgtct agaggaggac aagagggaga tccagccatg tccgaagagg agtttccttc
5941 gctctgcctc tctaggtcga agggcctcct tccatctgga atgtctaaag cgacaaaagg
6001 atcaaggggg agacatctct cagaagacag ccttgccctt gcatctggtt catcaccagg
6061 cattggcagt ggcaggcttg agccccctcc tgcagagaag ccattctcct tccacgtttc
6121 ccaggccacg ccccacgccc cctgtcactc caggcagccg gggcaggccc ctacagccca
6181 tccctaccct gcggctggag ggggcggagt ccagtgagaa actcaacagc agcttcccgt
6241 ccatccactg cagctcctgg tcagaggaga ccacagcctg tagtgggggc agcagcatgg
6301 cccggagagc ccggcccgtc tccctcaccg tgcccagcca ggctggagct ccaggcagac
6361 agttccacgg cagtgccagc agcctggtgg aagcggtctt gatttcagaa ggactgggac
6421 agtttgctca agatcccaag ttcatcgagg tcaccacaca ggagctggct gacgcctgcg
6481 atatgacaat agaggagatg gagaacgccg cagacaacat cctcagcggg ggcgcccagc
6541 agagccccaa cggcaccctc ttaccttttg tgaactgcag ggacccaggg caggacaggg
6601 ctgtggtccc agaggacgag agctgtgtat atgccctggg gcgaggccgg agcgaggaag
6661 cgctcccgga cagcaggtcc tatgtcagca acctgtagtc cgcaggctgg cgagacgcgg
6721 gtgtttttta ttcgtttcaa tgttcctaat gggttcgttt cagaagtgcc tcactgttct
6781 cgtgacctgg aggtaaccgg aacagcgtct tcattcactg ctgtcgggat aagcctcaga
6841 gctgggcggt gtaccgaagt cggcttttca gggagaagcc aaggccgttg gtgcgggggc
6901 tccagcacct tcccacggca gcaccgccca aaggacccca ccccccctaa gcaaaagggt
6961 gttttcccct tgcttgtata aacagtcatt tgcacatgtt ctgtctgagc ctggccgtct
7021 ctatggagca gggccccagg gatctatggc aggaatgggc cagtgtcccc agtaggagcc
7081 ggaaggtggc tgcaaggttc ccagcagtgc agatctggtc cctatgtccc ttcagggacc
7141 cttcccctgc tggaactgag gagcaggtgc aggagccagt gcagaccaca ccacctgccc
7201 tcagctagcc agacctgggg gcgcaggctg cttgcctggt gctctgggtt tcatagtttg
7261 atggttcttg tcagcatgtt gcggttttct aggttttgat ttctttatta ctatttgttg
7321 tgttttccac ggggagggga ggaagaagag cgtttacaac tgcgcagcct cacttcaccg
7381 gttccacatt tgcatattta agttggattt ggtttattgt attctttaaa tggtgcggtc
7441 caacccccac cctcacccct attggagcaa gggttcatta tcaccaacgg ggttcattat
7501 caaccaacgg ggaggtttta cctgctctgt gtatgcccaa gtaacatgtt acaattttcc
7561 ttaagtcaaa gcaacttttt cccctttcgg tttggttgag catcacgacc tgcaggttaa
7621 cagtcagttt agataaggcg gtgtgtgcct gggcgactga gctgggctcc tttctgggca
7681 tatggattgg ttcaggagag aagaaatatg ggcatctttg cgtcacacgt gtgtccatag
7741 tgggtcgtct tgtgtgtctg tgcatccaca cggtacgtga gcaccccgcc ccacccccgc
7801 tcaaagtctg tagatcccgt tcgggtttga cggccgggga gttcaaaatc tggggcgatt
7861 cgaaagcaag aacaaaccac tgtctctgct tctgcttctg aaacgagaat ctggtaactg
7921 cattttctgt cccacgagat atgcaaaagc aatgcaataa tatccatttt aaaatacgat
7981 tgtgagttgt gtcacagcat taaaattcta ttttaaaaaa aacatgaaat ttaaggggaa
8041 aaactccaag aagacatttt gactttcgat atattctgtg taatgtttta ttgcattgat
8101 aatgtttctg ttgaagaaac tgttatactt gaattcaggt cagtttcagt atttttcaaa
8161 tattttttta aaactgaatt gcaattgtgc cttgcaaata taatgactta agtttgtttt
8221 aaaattcact tcttgtatat tttgctgcat gtaaagtaaa tcattttgta tttggaaaaa
8281 aaaaaaaaaa aaaaaaaaaa aaaaa
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