GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS RATTRO06 101 bp ds-DNA ROD 16-JAN-1991 DEFINITION Rat skeletal muscle beta-tropomyosin and fibroblast tropomyosin 1 gene, alternative exon 6. ACCESSION L00377 M12080 M14127 KEYWORDS alternate splicing; tropomyosin. SEGMENT 6 of 11 SOURCE Rat adult rat skeletal muscle, cDNA to mRNA, clone pRSkM-22 [Mol. Cell. Biol. 6, 3582-3595 (1986)]; embryonic fibroblast, cDNA to mRNA [J. Biol. Chem. 260, 14440-14445 (1985)]; DNA, library of R.O.Hynes [Mol. Cell. Biol. 6, 3582-3595 (1986)]. ORGANISM Rattus norvegicus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 101) AUTHORS Helfman,D.M., Cheley,S., Kuismanen,E., Finn,L.A. and Yamawaki-Kataoka,Y. TITLE Nonmuscle and muscle tropomyosin isoforms are expressed from a single gene by alternative RNA splicing and polyadenylation JOURNAL Mol. Cell. Biol. 6, 3582-3595 (1986) STANDARD full staff_review REFERENCE 2 (bases 16 to 91) AUTHORS Valiante,N.M. and Caton,A.J. TITLE A new Igk-V gene family in the mouse JOURNAL Immunogenetics 32, 345-350 (1990) STANDARD full staff_review FEATURES Location/Qualifiers precursor_RNA <1..>101 /note="beta mRNA and intron" precursor_RNA <1..>101 /note="trop1 mRNA and intron" intron <1..15 /note="trop1 intron E" intron <1..>101 /note="beta intron E" exon 16..91 /note="embryonic fibroblast tropomyosin 1, exon 6" intron 92..>101 /note="trop1 intron F" BASE COUNT 22 a 31 c 33 g 15 t ORIGIN About 150 bp after segment 5. 1 gccccctgcc cccagccgag ctaggcagct ggaggaggag cttcgaacca tggaccaggc 61 tctcaagtcg ctgatagcct cagaggagga ggtagtagcc t //
GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS RATTRO05 96 bp ds-DNA ROD 16-JAN-1991 DEFINITION Rat skeletal muscle beta-tropomyosin and fibroblast tropomyosin 1 gene, exon 5. ACCESSION L00376 M12080 M14127 KEYWORDS alternate splicing; tropomyosin. SEGMENT 5 of 11 SOURCE Rat adult rat skeletal muscle, cDNA to mRNA, clone pRSkM-22 [Mol. Cell. Biol. 6, 3582-3595 (1986)]; embryonic fibroblast, cDNA to mRNA [J. Biol. Chem. 260, 14440-14445 (1985)]; DNA, library of R.O.Hynes [Mol. Cell. Biol. 6, 3582-3595 (1986)]. ORGANISM Rattus norvegicus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 96) AUTHORS Helfman,D.M., Cheley,S., Kuismanen,E., Finn,L.A. and Yamawaki-Kataoka,Y. TITLE Nonmuscle and muscle tropomyosin isoforms are expressed from a single gene by alternative RNA splicing and polyadenylation JOURNAL Mol. Cell. Biol. 6, 3582-3595 (1986) STANDARD full staff_review REFERENCE 2 (bases 16 to 86) AUTHORS Valiante,N.M. and Caton,A.J. TITLE A new Igk-V gene family in the mouse JOURNAL Immunogenetics 32, 345-350 (1990) STANDARD full staff_review FEATURES Location/Qualifiers precursor_RNA <1..>96 /note="beta mRNA and intron" precursor_RNA <1..>96 /note="trop1 mRNA and intron" intron <1..15 /note="beta intron D" intron <1..15 /note="trop1 intron D" exon 16..86 /note="skeletal muscle beta-tropomyosin, exon 5" exon 16..86 /note="embryonic fibroblast tropomyosin 1, exon 5" intron 87..>96 /note="beta intron E" intron 87..>96 /note="trop1 intron E" BASE COUNT 21 a 22 c 38 g 15 t ORIGIN About 100 bp after segment 3. 1 cccgcttccc ctcaggtggc caggaagctg gtgatcctgg aaggagagct ggagcgctct 61 gaagagagag ccgaggtggc tgagaggtag ggatac //
GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS RATTRO02 151 bp ds-DNA ROD 16-JAN-1991 DEFINITION Rat skeletal muscle beta-tropomyosin and fibroblast tropomyosin 1 gene, exon 2. ACCESSION L00373 M12080 M14127 KEYWORDS alternate splicing; tropomyosin. SEGMENT 2 of 11 SOURCE Rat adult rat skeletal muscle, cDNA to mRNA, clone pRSkM-22 [Mol. Cell. Biol. 6, 3582-3595 (1986)]; embryonic fibroblast, cDNA to mRNA [J. Biol. Chem. 260, 14440-14445 (1985)]; DNA, library of R.O.Hynes [Mol. Cell. Biol. 6, 3582-3595 (1986)]. ORGANISM Rattus norvegicus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 151) AUTHORS Helfman,D.M., Cheley,S., Kuismanen,E., Finn,L.A. and Yamawaki-Kataoka,Y. TITLE Nonmuscle and muscle tropomyosin isoforms are expressed from a single gene by alternative RNA splicing and polyadenylation JOURNAL Mol. Cell. Biol. 6, 3582-3595 (1986) STANDARD full staff_review REFERENCE 2 (bases 16 to 141) AUTHORS Valiante,N.M. and Caton,A.J. TITLE A new Igk-V gene family in the mouse JOURNAL Immunogenetics 32, 345-350 (1990) STANDARD full staff_review FEATURES Location/Qualifiers precursor_RNA <1..>151 /note="beta mRNA and intron" precursor_RNA <1..>151 /note="trop1 mRNA and intron" intron <1..15 /note="beta intron A" intron <1..15 /note="trop1 intron A" exon 16..141 /note="skeletal muscle beta-tropomyosin, exon 2" exon 16..141 /note="embryonic fibroblast tropomyosin 1, exon 2" intron 142..>151 /note="beta intron B" intron 142..>151 /note="trop1 intron B" BASE COUNT 45 a 32 c 53 g 21 t ORIGIN About 0.5 kb after segment 1. 1 ccccttcttc cacagctgga ggaagagcag caggccctcc agaagaaact gaaggggaca 61 gaggatgagg tggaaaagta ttccgagtct gtgaaggatg cccaggagaa actggagcag 121 gccgagaaga aggccaccga tgtgagtgtg g //
GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS RATTRO03 159 bp ds-DNA ROD 16-JAN-1991 DEFINITION Rat skeletal muscle beta-tropomyosin and fibroblast tropomyosin 1 gene, exon 3. ACCESSION L00374 M12080 M14127 KEYWORDS alternate splicing; tropomyosin. SEGMENT 3 of 11 SOURCE Rat adult rat skeletal muscle, cDNA to mRNA, clone pRSkM-22 [Mol. Cell. Biol. 6, 3582-3595 (1986)]; embryonic fibroblast, cDNA to mRNA [J. Biol. Chem. 260, 14440-14445 (1985)]; DNA, library of R.O.Hynes [Mol. Cell. Biol. 6, 3582-3595 (1986)]. ORGANISM Rattus norvegicus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 159) AUTHORS Helfman,D.M., Cheley,S., Kuismanen,E., Finn,L.A. and Yamawaki-Kataoka,Y. TITLE Nonmuscle and muscle tropomyosin isoforms are expressed from a single gene by alternative RNA splicing and polyadenylation JOURNAL Mol. Cell. Biol. 6, 3582-3595 (1986) STANDARD full staff_review REFERENCE 2 (bases 16 to 149) AUTHORS Valiante,N.M. and Caton,A.J. TITLE A new Igk-V gene family in the mouse JOURNAL Immunogenetics 32, 345-350 (1990) STANDARD full staff_review FEATURES Location/Qualifiers precursor_RNA <1..>159 /note="beta mRNA and intron" precursor_RNA <1..>159 /note="trop1 mRNA and intron" intron <1..15 /note="beta intron B" intron <1..15 /note="trop1 intron B" exon 16..149 /note="skeletal muscle beta-tropomyosin, exon 3" exon 16..149 /note="embryonic fibroblast tropomyosin 1, exon 3" intron 150..>159 /note="beta intron C" intron 150..>159 /note="trop1 intron C" BASE COUNT 39 a 36 c 58 g 26 t ORIGIN About 2.5 kb after segment 2. 1 ccctctgacc cacaggctga agcagatgtg gcttctctga atcgacgcat tcagctcgta 61 gaggaggagt tggatcgggc acaggagcgc ctggctacag ccttgcaaaa gctggaggag 121 gctgagaaag ccgctgatga gagcgagagg tggggaagg //
GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS RATTRO04 143 bp ds-DNA ROD 16-JAN-1991 DEFINITION Rat skeletal muscle beta-tropomyosin and fibroblast tropomyosin 1 gene, exon 4. ACCESSION L00375 M12080 M14127 KEYWORDS alternate splicing; tropomyosin. SEGMENT 4 of 11 SOURCE Rat adult rat skeletal muscle, cDNA to mRNA, clone pRSkM-22 [Mol. Cell. Biol. 6, 3582-3595 (1986)]; embryonic fibroblast, cDNA to mRNA [J. Biol. Chem. 260, 14440-14445 (1985)]; DNA, library of R.O.Hynes [Mol. Cell. Biol. 6, 3582-3595 (1986)]. ORGANISM Rattus norvegicus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 143) AUTHORS Helfman,D.M., Cheley,S., Kuismanen,E., Finn,L.A. and Yamawaki-Kataoka,Y. TITLE Nonmuscle and muscle tropomyosin isoforms are expressed from a single gene by alternative RNA splicing and polyadenylation JOURNAL Mol. Cell. Biol. 6, 3582-3595 (1986) STANDARD full staff_review REFERENCE 2 (bases 16 to 133) AUTHORS Valiante,N.M. and Caton,A.J. TITLE A new Igk-V gene family in the mouse JOURNAL Immunogenetics 32, 345-350 (1990) STANDARD full staff_review FEATURES Location/Qualifiers precursor_RNA <1..>143 /note="beta mRNA and intron" precursor_RNA <1..>143 /note="trop1 mRNA and intron" intron <1..15 /note="beta intron C" intron <1..15 /note="trop1 intron C" exon 16..133 /note="skeletal muscle beta-tropomyosin, exon 4" exon 16..133 /note="embryonic fibroblast tropomyosin 1, exon 4" intron 134..>143 /note="beta intron D" intron 134..>143 /note="trop1 intron D" BASE COUNT 45 a 30 c 47 g 21 t ORIGIN About 250 bp after segment 3. 1 gtccctgctt ctcagaggaa tgaaggtcat tgagaaccgg gccatgaagg atgaggagaa 61 gatggagctg caggagatgc agctgaaaga agccaagcac atcgctgagg actcagaccg 121 caaatacgag gaggtgacag cct //
GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS RATTRO11 168 bp ds-DNA ROD 16-JAN-1991 DEFINITION Rat skeletal muscle beta-tropomyosin and fibroblast tropomyosin 1 gene, alternative exon 9. ACCESSION L00382 M14127 KEYWORDS alternate splicing; tropomyosin. SEGMENT 11 of 11 SOURCE Rat adult rat skeletal muscle, cDNA to mRNA, clone pRSkM-22 [Mol. Cell. Biol. 6, 3582-3595 (1986)]; embryonic fibroblast, cDNA to mRNA [J. Biol. Chem. 260, 14440-14445 (1985)]; DNA, library of R.O.Hynes [Mol. Cell. Biol. 6, 3582-3595 (1986)]. ORGANISM Rattus norvegicus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 168) AUTHORS Helfman,D.M., Cheley,S., Kuismanen,E., Finn,L.A. and Yamawaki-Kataoka,Y. TITLE Nonmuscle and muscle tropomyosin isoforms are expressed from a single gene by alternative RNA splicing and polyadenylation JOURNAL Mol. Cell. Biol. 6, 3582-3595 (1986) STANDARD full staff_review REFERENCE 2 (bases 16 to 168) AUTHORS Valiante,N.M. and Caton,A.J. TITLE A new Igk-V gene family in the mouse JOURNAL Immunogenetics 32, 345-350 (1990) STANDARD full staff_review FEATURES Location/Qualifiers precursor_RNA <1..168 /note="trop1 mRNA" intron <1..15 /note="trop1 intron H" CDS join(L00372:617..730, L00373:16..141,L00374:16..149,L00375:16..133, L00376:16..86,L00377:16..91,L00379:16..78, L00380:16..85,16..98) /note="embryonic fibroblast tropomyosin 1" exon 16..98 /note="embryonic fibroblast tropomyosin 1, exon 9" BASE COUNT 43 a 51 c 40 g 34 t ORIGIN About 0.85 kb after segment 10. 1 tgcttcccct cacagagact ttggctagtg ccaaggaaga gaacgtggag attcaccaga 61 ccttggacca gacccttctg gaactcaaca acctgtaagg gtggccctgc tacctgccga 121 ccagactaca tagatgcctc ctcaggccaa taaacggatg tctctggc //
GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS RATTRO08 88 bp ds-DNA ROD 16-JAN-1991 DEFINITION Rat skeletal muscle beta-tropomyosin and fibroblast tropomyosin 1 gene, exon 7. ACCESSION L00379 M12080 M14127 KEYWORDS alternate splicing; tropomyosin. SEGMENT 8 of 11 SOURCE Rat adult rat skeletal muscle, cDNA to mRNA, clone pRSkM-22 [Mol. Cell. Biol. 6, 3582-3595 (1986)]; embryonic fibroblast, cDNA to mRNA [J. Biol. Chem. 260, 14440-14445 (1985)]; DNA, library of R.O.Hynes [Mol. Cell. Biol. 6, 3582-3595 (1986)]. ORGANISM Rattus norvegicus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 88) AUTHORS Helfman,D.M., Cheley,S., Kuismanen,E., Finn,L.A. and Yamawaki-Kataoka,Y. TITLE Nonmuscle and muscle tropomyosin isoforms are expressed from a single gene by alternative RNA splicing and polyadenylation JOURNAL Mol. Cell. Biol. 6, 3582-3595 (1986) STANDARD full staff_review REFERENCE 2 (bases 16 to 78) AUTHORS Valiante,N.M. and Caton,A.J. TITLE A new Igk-V gene family in the mouse JOURNAL Immunogenetics 32, 345-350 (1990) STANDARD full staff_review FEATURES Location/Qualifiers precursor_RNA <1..>88 /note="beta mRNA and intron" precursor_RNA <1..>88 /note="trop1 mRNA and intron" intron <1..15 /note="beta intron F" intron <1..15 /note="trop1 intron F" exon 16..78 /note="skeletal muscle beta-tropomyosin, exon 7" exon 16..78 /note="embryonic fibroblast tropomyosin 1, exon 7" variation 74..74 /note="a in cDNA [J. Biol. Chem. 260, 14440-14445 (1985)],[Mol. Cell. Biol. 6, 3582-3595 (1986)]; g in DNA [Mol. Cell. Biol. 6, 3582-3595 (1986)] (table 1)" intron 79..>88 /note="beta intron G" intron 79..>88 /note="trop1 intron G" BASE COUNT 33 a 14 c 23 g 18 t ORIGIN About 150 bp after segment 7. 1 gtttgtctct taaagtattc caccaaagag gacaaatacg aagaagagat caaacttctg 61 gaggagaagc tgaaggaggt gagactac //
GenBank-Updates@genbank.bio.net (01/16/91)
LOCUS RATTRO01 755 bp ds-DNA ROD 16-JAN-1991 DEFINITION Rat skeletal muscle beta-tropomyosin and fibroblast tropomyosin 1 gene, exon 1. ACCESSION L00372 M12080 M14127 KEYWORDS alternate splicing; tropomyosin. SEGMENT 1 of 11 SOURCE Rat adult rat skeletal muscle, cDNA to mRNA, clone pRSkM-22 [Mol. Cell. Biol. 6, 3582-3595 (1986)]; embryonic fibroblast, cDNA to mRNA [J. Biol. Chem. 260, 14440-14445 (1985)]; DNA, library of R.O.Hynes [Mol. Cell. Biol. 6, 3582-3595 (1986)]. ORGANISM Rattus norvegicus Eukaryota; Animalia; Metazoa; Chordata; Vertebrata; Mammalia; Theria; Eutheria; Rodentia; Myomorpha; Muridae; Murinae. REFERENCE 1 (bases 1 to 755) AUTHORS Helfman,D.M., Cheley,S., Kuismanen,E., Finn,L.A. and Yamawaki-Kataoka,Y. TITLE Nonmuscle and muscle tropomyosin isoforms are expressed from a single gene by alternative RNA splicing and polyadenylation JOURNAL Mol. Cell. Biol. 6, 3582-3595 (1986) STANDARD full staff_review REFERENCE 2 (bases 555 to 729) AUTHORS Valiante,N.M. and Caton,A.J. TITLE A new Igk-V gene family in the mouse JOURNAL Immunogenetics 32, 345-350 (1990) STANDARD full staff_review FEATURES Location/Qualifiers precursor_RNA 505..>755 /note="beta mRNA (alt.)" precursor_RNA 505..>755 /note="trop1 mRNA (alt.)" precursor_RNA 507..>755 /note="beta mRNA (alt.)" precursor_RNA 507..>755 /note="trop1 mRNA (alt.)" exon 617..730 /note="skeletal muscle beta-tropomyosin, exon 1" exon 617..730 /note="embryonic fibroblast tropomyosin 1, exon 1" intron 731..>755 /note="beta intron A" intron 731..>755 /note="trop1 intron A" BASE COUNT 142 a 245 c 243 g 125 t ORIGIN 615 bp upstream of NcoI site. 1 cccggggtaa actgaggcac tcgaggcgtg caggagatcc gcctcccaag agacatttaa 61 tctgggggga tttacaggaa acttctaaat taagggtagc ggctgctgct agctgaggga 121 gggcacgcgg tctctgtgcc caggcagctg ccgtgacgtc acgccctgaa atagccccgg 181 ggccccagcc gcagctgccg ctgggcccgc ctgtcactca gaggaagcgc tgagcccccg 241 gcccaagggt cttgtagcct ctgctgacca aggtttttac agcccgcagt gagccagttt 301 tgcttccgac ggctggctgg ggaagaagga ggcgggggcc gggatccgag ggggcggacc 361 cgaggggtgg gcgcaaaggg tggccgcgcc caagaccggg cagtgcgtct gcccctacaa 421 ggtttgggcc ttggtggggg agggtcctgg tcccccggct ccgcccggct tctccccgcc 481 ttttagcgcc cgcgctgctg ggacatcaca gtccctcttg atcctcctaa cctgtcccgg 541 gtgcatcagt gctctcggct agcccggtct acctactctt caccgctcgc ccgccggccc 601 actccccacc gcagccatgg acgccatcaa gaagaagatg cagatgctga aactggacaa 661 ggagaatgcc atcgaccgcg cagagcaggc cgaagccgac aagaagcaag ctgaagaccg 721 atgcaagcag gtggggccca ccccttcttc cacag //